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Items: 1 to 50 of 96

1.

Signaling Pathways, Chemical and Biological Modulators of Nucleotide Excision Repair: The Faithful Shield against UV Genotoxicity.

Kobaisi F, Fayyad N, Rezvani HR, Fayyad-Kazan M, Sulpice E, Badran B, Fayyad-Kazan H, Gidrol X, Rachidi W.

Oxid Med Cell Longev. 2019 Aug 7;2019:4654206. doi: 10.1155/2019/4654206. eCollection 2019. Review.

2.

Building blocks for a European Organ-on-Chip roadmap.

Mastrangeli M, Millet S, Mummery C, Loskill P, Braeken D, Eberle W, Cipriano M, Fernandez L, Graef M, Gidrol X, Picollet-D'Hahan N, Van Meer B, Ochoa I, Schutte M, Van den Eijnden-van Raaij J.

ALTEX. 2019;36(3):481-492. doi: 10.14573/altex.1905221. No abstract available.

3.

Androgen receptor-modulatory microRNAs provide insight into therapy resistance and therapeutic targets in advanced prostate cancer.

Fletcher CE, Sulpice E, Combe S, Shibakawa A, Leach DA, Hamilton MP, Chrysostomou SL, Sharp A, Welti J, Yuan W, Dart DA, Knight E, Ning J, Francis JC, Kounatidou EE, Gaughan L, Swain A, Lupold SE, de Bono JS, McGuire SE, Gidrol X, Bevan CL.

Oncogene. 2019 Jul;38(28):5700-5724. doi: 10.1038/s41388-019-0823-5. Epub 2019 May 1.

4.

MYPT1 is targeted by miR-145 inhibiting viability, migration and invasion in 2D and 3D HeLa cultures.

González-Torres A, Bañuelos-Villegas EG, Martínez-Acuña N, Sulpice E, Gidrol X, Alvarez-Salas LM.

Biochem Biophys Res Commun. 2018 Dec 9;507(1-4):348-354. doi: 10.1016/j.bbrc.2018.11.039. Epub 2018 Nov 14.

PMID:
30446228
5.

Lens-free microscopy for 3D + time acquisitions of 3D cell culture.

Berdeu A, Laperrousaz B, Bordy T, Mandula O, Morales S, Gidrol X, Picollet-D'hahan N, Allier C.

Sci Rep. 2018 Oct 31;8(1):16135. doi: 10.1038/s41598-018-34253-6.

6.

Lens-free Video Microscopy for the Dynamic and Quantitative Analysis of Adherent Cell Culture.

Allier C, Vincent R, Navarro F, Menneteau M, Ghenim L, Gidrol X, Bordy T, Hervé L, Cioni O, Bardin S, Bornens M, Usson Y, Morales S.

J Vis Exp. 2018 Feb 23;(132). doi: 10.3791/56580.

PMID:
29553497
7.

Direct transfection of clonal organoids in Matrigel microbeads: a promising approach toward organoid-based genetic screens.

Laperrousaz B, Porte S, Gerbaud S, Härmä V, Kermarrec F, Hourtane V, Bottausci F, Gidrol X, Picollet-D'hahan N.

Nucleic Acids Res. 2018 Jul 6;46(12):e70. doi: 10.1093/nar/gky030.

8.

High-Content Monitoring of Drug Effects in a 3D Spheroid Model.

Mittler F, Obeïd P, Rulina AV, Haguet V, Gidrol X, Balakirev MY.

Front Oncol. 2017 Dec 11;7:293. doi: 10.3389/fonc.2017.00293. eCollection 2017.

9.

Microtubule stabilization drives 3D centrosome migration to initiate primary ciliogenesis.

Pitaval A, Senger F, Letort G, Gidrol X, Guyon L, Sillibourne J, Théry M.

J Cell Biol. 2017 Nov 6;216(11):3713-3728. doi: 10.1083/jcb.201610039. Epub 2017 Oct 9.

10.

Deciphering Cell Intrinsic Properties: A Key Issue for Robust Organoid Production.

Picollet-D'hahan N, Dolega ME, Freida D, Martin DK, Gidrol X.

Trends Biotechnol. 2017 Nov;35(11):1035-1048. doi: 10.1016/j.tibtech.2017.08.003. Epub 2017 Sep 17. Review.

PMID:
28927991
11.

A large-scale RNAi screen identifies LCMR1 as a critical regulator of Tspan8-mediated melanoma invasion.

Agaësse G, Barbollat-Boutrand L, Sulpice E, Bhajun R, El Kharbili M, Berthier-Vergnes O, Degoul F, de la Fouchardière A, Berger E, Voeltzel T, Lamartine J, Gidrol X, Masse I.

Oncogene. 2017 Aug 31;36(35):5084. doi: 10.1038/onc.2017.195. Epub 2017 Jun 19.

PMID:
28628117
12.

Comparative study of fully three-dimensional reconstruction algorithms for lens-free microscopy.

Berdeu A, Momey F, Laperrousaz B, Bordy T, Gidrol X, Dinten JM, Picollet-D'hahan N, Allier C.

Appl Opt. 2017 May 1;56(13):3939-3951. doi: 10.1364/AO.56.003939.

PMID:
28463289
13.

Imaging of dense cell cultures by multiwavelength lens-free video microscopy.

Allier C, Morel S, Vincent R, Ghenim L, Navarro F, Menneteau M, Bordy T, Hervé L, Cioni O, Gidrol X, Usson Y, Dinten JM.

Cytometry A. 2017 May;91(5):433-442. doi: 10.1002/cyto.a.23079. Epub 2017 Feb 27.

14.

Distinct outcomes of CRL-Nedd8 pathway inhibition reveal cancer cell plasticity.

Rulina AV, Mittler F, Obeid P, Gerbaud S, Guyon L, Sulpice E, Kermarrec F, Assard N, Dolega ME, Gidrol X, Balakirev MY.

Cell Death Dis. 2016 Dec 1;7(12):e2505. doi: 10.1038/cddis.2016.395.

15.

Refilins are short-lived Actin-bundling proteins that regulate lamellipodium protrusion dynamics.

Gay O, Gilquin B, Assard N, Stuelsatz P, Delphin C, Lachuer J, Gidrol X, Baudier J.

Biol Open. 2016 Oct 15;5(10):1351-1361. doi: 10.1242/bio.019588.

16.

Label-Free Electric Monitoring of Human Cancer Cells as a Potential Diagnostic Tool.

Vaillier C, Honegger T, Kermarrec F, Gidrol X, Peyrade D.

Anal Chem. 2016 Sep 20;88(18):9022-8. doi: 10.1021/acs.analchem.6b01648. Epub 2016 Sep 1.

PMID:
27562118
17.

A 3D Toolbox to Enhance Physiological Relevance of Human Tissue Models.

Picollet-D'hahan N, Dolega ME, Liguori L, Marquette C, Le Gac S, Gidrol X, Martin DK.

Trends Biotechnol. 2016 Sep;34(9):757-769. doi: 10.1016/j.tibtech.2016.06.012. Epub 2016 Aug 4. Review.

PMID:
27497676
18.

A large-scale RNAi screen identifies LCMR1 as a critical regulator of Tspan8-mediated melanoma invasion.

Agaësse G, Barbollat-Boutrand L, Sulpice E, Bhajun R, El Kharbili M, Berthier-Vergnes O, Degoul F, de la Fouchardière A, Berger E, Voeltzel T, Lamartine J, Gidrol X, Masse I.

Oncogene. 2017 Jan 26;36(4):446-457. doi: 10.1038/onc.2016.219. Epub 2016 Jul 4. Erratum in: Oncogene. 2017 Jun 19;:.

PMID:
27375018
19.

Lensfree diffractive tomography for the imaging of 3D cell cultures.

Momey F, Berdeu A, Bordy T, Dinten JM, Marcel FK, Picollet-D'hahan N, Gidrol X, Allier C.

Biomed Opt Express. 2016 Feb 23;7(3):949-62. doi: 10.1364/BOE.7.000949. eCollection 2016 Mar 1.

20.

MicroRNA degeneracy and pluripotentiality within a Lavallière-tie architecture confers robustness to gene expression networks.

Bhajun R, Guyon L, Gidrol X.

Cell Mol Life Sci. 2016 Aug;73(15):2821-7. doi: 10.1007/s00018-016-2186-1. Epub 2016 Apr 1.

21.

Time-lapse contact microscopy of cell cultures based on non-coherent illumination.

Gabriel M, Balle D, Bigault S, Pornin C, Gétin S, Perraut F, Block MR, Chatelain F, Picollet-D'hahan N, Gidrol X, Haguet V.

Sci Rep. 2015 Oct 13;5:14532. doi: 10.1038/srep14532.

22.

Φ-score: A cell-to-cell phenotypic scoring method for sensitive and selective hit discovery in cell-based assays.

Guyon L, Lajaunie C, Fer F, Bhajun R, Sulpice E, Pinna G, Campalans A, Radicella JP, Rouillier P, Mary M, Combe S, Obeid P, Vert JP, Gidrol X.

Sci Rep. 2015 Sep 18;5:14221. doi: 10.1038/srep14221.

23.

Wss1 metalloprotease partners with Cdc48/Doa1 in processing genotoxic SUMO conjugates.

Balakirev MY, Mullally JE, Favier A, Assard N, Sulpice E, Lindsey DF, Rulina AV, Gidrol X, Wilkinson KD.

Elife. 2015 Sep 8;4. doi: 10.7554/eLife.06763.

24.

A kinome-targeted RNAi-based screen links FGF signaling to H2AX phosphorylation in response to radiation.

Benzina S, Pitaval A, Lemercier C, Lustremant C, Frouin V, Wu N, Papine A, Soussaline F, Romeo PH, Gidrol X.

Cell Mol Life Sci. 2015 Sep;72(18):3559-73. doi: 10.1007/s00018-015-1901-7. Epub 2015 Apr 18.

25.

Point-of-care diagnostics for ricin exposure.

Diakite ML, Rollin J, Jary D, Berthier J, Mourton-Gilles C, Sauvaire D, Philippe C, Delapierre G, Gidrol X.

Lab Chip. 2015 May 21;15(10):2308-17. doi: 10.1039/c5lc00178a.

PMID:
25892365
26.

Controlled 3D culture in Matrigel microbeads to analyze clonal acinar development.

Dolega ME, Abeille F, Picollet-D'hahan N, Gidrol X.

Biomaterials. 2015 Jun;52:347-57. doi: 10.1016/j.biomaterials.2015.02.042. Epub 2015 Mar 3.

PMID:
25818441
27.

Involvement of membrane proteins and ion channels on the self-rotation of human cells in a non-rotating AC electric field.

Vaillier C, Honegger T, Kermarrec F, Gidrol X, Peyrade D.

Electrophoresis. 2015 May;36(9-10):1123-9. doi: 10.1002/elps.201400478. Epub 2015 Apr 27.

PMID:
25808576
28.

A statistically inferred microRNA network identifies breast cancer target miR-940 as an actin cytoskeleton regulator.

Bhajun R, Guyon L, Pitaval A, Sulpice E, Combe S, Obeid P, Haguet V, Ghorbel I, Lajaunie C, Gidrol X.

Sci Rep. 2015 Feb 12;5:8336. doi: 10.1038/srep08336.

29.

The wind rose of human keratinocyte cell fate.

Wu N, Gidrol X.

Cell Mol Life Sci. 2014 Dec;71(24):4697-702. doi: 10.1007/s00018-014-1758-1. Epub 2014 Oct 18.

30.

High-throughput monitoring of major cell functions by means of lensfree video microscopy.

Kesavan SV, Momey F, Cioni O, David-Watine B, Dubrulle N, Shorte S, Sulpice E, Freida D, Chalmond B, Dinten JM, Gidrol X, Allier C.

Sci Rep. 2014 Aug 6;4:5942. doi: 10.1038/srep05942.

31.

An EWOD-based microfluidic chip for single-cell isolation, mRNA purification and subsequent multiplex qPCR.

Rival A, Jary D, Delattre C, Fouillet Y, Castellan G, Bellemin-Comte A, Gidrol X.

Lab Chip. 2014 Oct 7;14(19):3739-49. doi: 10.1039/c4lc00592a.

PMID:
25080028
32.

Continuous microcarrier-based cell culture in a benchtop microfluidic bioreactor.

Abeille F, Mittler F, Obeid P, Huet M, Kermarrec F, Dolega ME, Navarro F, Pouteau P, Icard B, Gidrol X, Agache V, Picollet-D'hahan N.

Lab Chip. 2014 Sep 21;14(18):3510-8. doi: 10.1039/c4lc00570h. Epub 2014 Jul 11.

PMID:
25012393
33.

Facile bench-top fabrication of enclosed circular microchannels provides 3D confined structure for growth of prostate epithelial cells.

Dolega ME, Wagh J, Gerbaud S, Kermarrec F, Alcaraz JP, Martin DK, Gidrol X, Picollet-D'hahan N.

PLoS One. 2014 Jun 19;9(6):e99416. doi: 10.1371/journal.pone.0099416. eCollection 2014.

34.

Comprehensive analysis of human cells motion under an irrotational AC electric field in an electro-microfluidic chip.

Vaillier C, Honegger T, Kermarrec F, Gidrol X, Peyrade D.

PLoS One. 2014 Apr 15;9(4):e95231. doi: 10.1371/journal.pone.0095231. eCollection 2014.

35.

Human bone marrow mesenchymal stem cells regulate biased DNA segregation in response to cell adhesion asymmetry.

Freida D, Lecourt S, Cras A, Vanneaux V, Letort G, Gidrol X, Guyon L, Larghero J, Thery M.

Cell Rep. 2013 Nov 14;5(3):601-10. doi: 10.1016/j.celrep.2013.09.019. Epub 2013 Oct 17.

36.

The modulation of attachment, growth and morphology of cancerous prostate cells by polyelectrolyte nanofilms.

Picollet-D'hahan N, Gerbaud S, Kermarrec F, Alcaraz JP, Obeid P, Bhajun R, Guyon L, Sulpice E, Cinquin P, Dolega ME, Wagh J, Gidrol X, Martin DK.

Biomaterials. 2013 Dec;34(38):10099-108. doi: 10.1016/j.biomaterials.2013.08.093. Epub 2013 Sep 21.

37.

Immunogenic calreticulin exposure occurs through a phylogenetically conserved stress pathway involving the chemokine CXCL8.

Sukkurwala AQ, Martins I, Wang Y, Schlemmer F, Ruckenstuhl C, Durchschlag M, Michaud M, Senovilla L, Sistigu A, Ma Y, Vacchelli E, Sulpice E, Gidrol X, Zitvogel L, Madeo F, Galluzzi L, Kepp O, Kroemer G.

Cell Death Differ. 2014 Jan;21(1):59-68. doi: 10.1038/cdd.2013.73. Epub 2013 Jun 21.

38.

The opportunistic pathogen Pseudomonas aeruginosa activates the DNA double-strand break signaling and repair pathway in infected cells.

Elsen S, Collin-Faure V, Gidrol X, Lemercier C.

Cell Mol Life Sci. 2013 Nov;70(22):4385-97. doi: 10.1007/s00018-013-1392-3. Epub 2013 Jun 13.

39.

Label-free analysis of prostate acini-like 3D structures by lensfree imaging.

Dolega ME, Allier C, Kesavan SV, Gerbaud S, Kermarrec F, Marcoux P, Dinten JM, Gidrol X, Picollet-D'Hahan N.

Biosens Bioelectron. 2013 Nov 15;49:176-83. doi: 10.1016/j.bios.2013.05.001. Epub 2013 May 21.

PMID:
23747358
40.

The miR-17 family links p63 protein to MAPK signaling to promote the onset of human keratinocyte differentiation.

Wu N, Sulpice E, Obeid P, Benzina S, Kermarrec F, Combe S, Gidrol X.

PLoS One. 2012;7(9):e45761. doi: 10.1371/journal.pone.0045761. Epub 2012 Sep 24.

41.

Cardiac glycosides exert anticancer effects by inducing immunogenic cell death.

Menger L, Vacchelli E, Adjemian S, Martins I, Ma Y, Shen S, Yamazaki T, Sukkurwala AQ, Michaud M, Mignot G, Schlemmer F, Sulpice E, Locher C, Gidrol X, Ghiringhelli F, Modjtahedi N, Galluzzi L, André F, Zitvogel L, Kepp O, Kroemer G.

Sci Transl Med. 2012 Jul 18;4(143):143ra99. doi: 10.1126/scitranslmed.3003807.

42.

Transcriptome analysis of muscle in horses suffering from recurrent exertional rhabdomyolysis revealed energetic pathway alterations and disruption in the cytosolic calcium regulation.

Barrey E, Jayr L, Mucher E, Gospodnetic S, Joly F, Benech P, Alibert O, Gidrol X, Mata X, Vaiman A, Guérin G.

Anim Genet. 2012 Jun;43(3):271-81. doi: 10.1111/j.1365-2052.2011.02246.x. Epub 2011 Sep 27.

PMID:
22486498
43.

[Mitochondria, microRNA and RNA interference].

Bandiera S, Barrey E, Ernoult-Lange M, Gidrol X, Henrion-Caude A, Huang L, Saint-Auret G, Weil D.

Med Sci (Paris). 2012 Jan;28(1):23-6. doi: 10.1051/medsci/2012281008. Epub 2012 Jan 27. French. No abstract available.

44.

p63 regulates human keratinocyte proliferation via MYC-regulated gene network and differentiation commitment through cell adhesion-related gene network.

Wu N, Rollin J, Masse I, Lamartine J, Gidrol X.

J Biol Chem. 2012 Feb 17;287(8):5627-38. doi: 10.1074/jbc.M111.328120. Epub 2011 Dec 19.

45.

Pre-microRNA and mature microRNA in human mitochondria.

Barrey E, Saint-Auret G, Bonnamy B, Damas D, Boyer O, Gidrol X.

PLoS One. 2011;6(5):e20220. doi: 10.1371/journal.pone.0020220. Epub 2011 May 26.

46.

Large scale RNAi screen reveals that the inhibitor of DNA binding 2 (ID2) protein is repressed by p53 family member p63 and functions in human keratinocyte differentiation.

Wu N, Castel D, Debily MA, Vigano MA, Alibert O, Mantovani R, Iljin K, Romeo PH, Gidrol X.

J Biol Chem. 2011 Jun 10;286(23):20870-9. doi: 10.1074/jbc.M110.169433. Epub 2011 Apr 10.

47.

Characterization of the transcriptional signature of C/EBPbeta isoforms (LAP/LIP) in Hep3B cells: implication of LIP in pro-survival functions.

Saint-Auret G, Danan JL, Hiron M, Blache C, Sulpice E, Tendil S, Daveau M, Gidrol X, Salier JP.

J Hepatol. 2011 Jun;54(6):1185-94. doi: 10.1016/j.jhep.2010.09.021. Epub 2010 Oct 31.

PMID:
21145827
48.

Monitoring impedance changes associated with motility and mitosis of a single cell.

Ghenim L, Kaji H, Hoshino Y, Ishibashi T, Haguet V, Gidrol X, Nishizawa M.

Lab Chip. 2010 Oct 7;10(19):2546-50. doi: 10.1039/c004115g. Epub 2010 Aug 2.

PMID:
20676434
49.

Gene association networks from microarray data using a regularized estimation of partial correlation based on PLS regression.

Tenenhaus A, Guillemot V, Gidrol X, Frouin V.

IEEE/ACM Trans Comput Biol Bioinform. 2010 Apr-Jun;7(2):251-62. doi: 10.1109/TCBB.2008.87.

PMID:
20431145
50.

Natural single-nucleosome epi-polymorphisms in yeast.

Nagarajan M, Veyrieras JB, de Dieuleveult M, Bottin H, Fehrmann S, Abraham AL, Croze S, Steinmetz LM, Gidrol X, Yvert G.

PLoS Genet. 2010 Apr 22;6(4):e1000913. doi: 10.1371/journal.pgen.1000913.

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