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Items: 34


IL-10 Impairs Local Immune Response in Lung Granulomas and Lymph Nodes during Early Mycobacterium tuberculosis Infection.

Wong EA, Evans S, Kraus CR, Engelman KD, Maiello P, Flores WJ, Cadena AM, Klein E, Thomas K, White AG, Causgrove C, Stein B, Tomko J, Mattila JT, Gideon H, Lin PL, Reimann KA, Kirschner DE, Flynn JL.

J Immunol. 2020 Feb 1;204(3):644-659. doi: 10.4049/jimmunol.1901211. Epub 2019 Dec 20.


Neutrophils express pro- and anti-inflammatory cytokines in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques.

Gideon HP, Phuah J, Junecko BA, Mattila JT.

Mucosal Immunol. 2019 Nov;12(6):1370-1381. doi: 10.1038/s41385-019-0195-8. Epub 2019 Aug 21.


Boosting BCG with proteins or rAd5 does not enhance protection against tuberculosis in rhesus macaques.

Darrah PA, DiFazio RM, Maiello P, Gideon HP, Myers AJ, Rodgers MA, Hackney JA, Lindenstrom T, Evans T, Scanga CA, Prikhodko V, Andersen P, Lin PL, Laddy D, Roederer M, Seder RA, Flynn JL.

NPJ Vaccines. 2019 May 28;4:21. doi: 10.1038/s41541-019-0113-9. eCollection 2019.


Developing a grass-roots method for monitoring medicines shortages in southern Africa: Report of a pilot in Namibia.

Rennie T, Kibuule D, Lates J, Gideon H, Nangombe V, Hunter CJ.

Res Social Adm Pharm. 2019 Apr 19. pii: S1551-7411(18)30996-3. doi: 10.1016/j.sapharm.2019.04.046. [Epub ahead of print]


CD4CD8 Double Positive T cell responses during Mycobacterium tuberculosis infection in cynomolgus macaques.

Diedrich CR, Gideon HP, Rutledge T, Baranowski TM, Maiello P, Myers AJ, Lin PL.

J Med Primatol. 2019 Apr;48(2):82-89. doi: 10.1111/jmp.12399. Epub 2019 Feb 5.


Lymph nodes are sites of prolonged bacterial persistence during Mycobacterium tuberculosis infection in macaques.

Ganchua SKC, Cadena AM, Maiello P, Gideon HP, Myers AJ, Junecko BF, Klein EC, Lin PL, Mattila JT, Flynn JL.

PLoS Pathog. 2018 Nov 1;14(11):e1007337. doi: 10.1371/journal.ppat.1007337. eCollection 2018 Nov.


Concurrent infection with Mycobacterium tuberculosis confers robust protection against secondary infection in macaques.

Cadena AM, Hopkins FF, Maiello P, Carey AF, Wong EA, Martin CJ, Gideon HP, DiFazio RM, Andersen P, Lin PL, Fortune SM, Flynn JL.

PLoS Pathog. 2018 Oct 12;14(10):e1007305. doi: 10.1371/journal.ppat.1007305. eCollection 2018 Oct.


Prospective Discrimination of Controllers From Progressors Early After Low-Dose Mycobacterium tuberculosis Infection of Cynomolgus Macaques using Blood RNA Signatures.

Thompson EG, Shankar S, Gideon HP, Braun J, Valvo J, Skinner JA, Aderem A, Flynn JL, Lin PL, Zak DE.

J Infect Dis. 2018 Mar 28;217(8):1318-1322. doi: 10.1093/infdis/jiy006.


PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis.

Lin PL, Maiello P, Gideon HP, Coleman MT, Cadena AM, Rodgers MA, Gregg R, O'Malley M, Tomko J, Fillmore D, Frye LJ, Rutledge T, DiFazio RM, Janssen C, Klein E, Andersen PL, Fortune SM, Flynn JL.

PLoS Pathog. 2016 Jul 5;12(7):e1005739. doi: 10.1371/journal.ppat.1005739. eCollection 2016 Jul.


Activation Profile of Mycobacterium tuberculosis-Specific CD4(+) T Cells Reflects Disease Activity Irrespective of HIV Status.

Wilkinson KA, Oni T, Gideon HP, Goliath R, Wilkinson RJ, Riou C.

Am J Respir Crit Care Med. 2016 Jun 1;193(11):1307-10. doi: 10.1164/rccm.201601-0116LE. No abstract available.


Computational and Empirical Studies Predict Mycobacterium tuberculosis-Specific T Cells as a Biomarker for Infection Outcome.

Marino S, Gideon HP, Gong C, Mankad S, McCrone JT, Lin PL, Linderman JJ, Flynn JL, Kirschner DE.

PLoS Comput Biol. 2016 Apr 11;12(4):e1004804. doi: 10.1371/journal.pcbi.1004804. eCollection 2016 Apr.


Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques.

Phuah J, Wong EA, Gideon HP, Maiello P, Coleman MT, Hendricks MR, Ruden R, Cirrincione LR, Chan J, Lin PL, Flynn JL.

Infect Immun. 2016 Apr 22;84(5):1301-1311. doi: 10.1128/IAI.00083-16. Print 2016 May.


Population tailored modification of tuberculosis specific interferon-gamma release assay.

Horvati K, Bősze S, Gideon HP, Bacsa B, Szabó TG, Goliath R, Rangaka MX, Hudecz F, Wilkinson RJ, Wilkinson KA.

J Infect. 2016 Feb;72(2):179-88. doi: 10.1016/j.jinf.2015.10.012. Epub 2015 Nov 26.


Immunology studies in non-human primate models of tuberculosis.

Flynn JL, Gideon HP, Mattila JT, Lin PL.

Immunol Rev. 2015 Mar;264(1):60-73. doi: 10.1111/imr.12258. Review.


Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization.

Gideon HP, Phuah J, Myers AJ, Bryson BD, Rodgers MA, Coleman MT, Maiello P, Rutledge T, Marino S, Fortune SM, Kirschner DE, Lin PL, Flynn JL.

PLoS Pathog. 2015 Jan 22;11(1):e1004603. doi: 10.1371/journal.ppat.1004603. eCollection 2015 Jan.


Computational modeling predicts IL-10 control of lesion sterilization by balancing early host immunity-mediated antimicrobial responses with caseation during mycobacterium tuberculosis infection.

Cilfone NA, Ford CB, Marino S, Mattila JT, Gideon HP, Flynn JL, Kirschner DE, Linderman JJ.

J Immunol. 2015 Jan 15;194(2):664-77. doi: 10.4049/jimmunol.1400734. Epub 2014 Dec 15.


Impairment of IFN-gamma response to synthetic peptides of Mycobacterium tuberculosis in a 7-day whole blood assay.

Gideon HP, Hamilton MS, Wood K, Pepper D, Oni T, Seldon R, Banwell C, Langford PR, Wilkinson RJ, Wilkinson KA.

PLoS One. 2013 Aug 8;8(8):e71351. doi: 10.1371/journal.pone.0071351. eCollection 2013.


Bioinformatic and empirical analysis of novel hypoxia-inducible targets of the human antituberculosis T cell response.

Gideon HP, Wilkinson KA, Rustad TR, Oni T, Guio H, Sherman DR, Vordermeier HM, Robertson BD, Young DB, Wilkinson RJ.

J Immunol. 2012 Dec 15;189(12):5867-76. doi: 10.4049/jimmunol.1202281. Epub 2012 Nov 19.


Smoking, BCG and employment and the risk of tuberculosis infection in HIV-infected persons in South Africa.

Oni T, Gideon HP, Bangani N, Tsekela R, Seldon R, Wood K, Wilkinson KA, Goliath RT, Ottenhoff TH, Wilkinson RJ.

PLoS One. 2012;7(10):e47072. doi: 10.1371/journal.pone.0047072. Epub 2012 Oct 9.


Conserved immune recognition hierarchy of mycobacterial PE/PPE proteins during infection in natural hosts.

Vordermeier HM, Hewinson RG, Wilkinson RJ, Wilkinson KA, Gideon HP, Young DB, Sampson SL.

PLoS One. 2012;7(8):e40890. doi: 10.1371/journal.pone.0040890. Epub 2012 Aug 1.


Risk factors associated with indeterminate gamma interferon responses in the assessment of latent tuberculosis infection in a high-incidence environment.

Oni T, Gideon HP, Bangani N, Tsekela R, Seldon R, Wood K, Wilkinson KA, Goliath RT, Ottenhoff TH, Wilkinson RJ.

Clin Vaccine Immunol. 2012 Aug;19(8):1243-7. doi: 10.1128/CVI.00166-12. Epub 2012 Jun 20.


The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection.

Lin PL, Dietrich J, Tan E, Abalos RM, Burgos J, Bigbee C, Bigbee M, Milk L, Gideon HP, Rodgers M, Cochran C, Guinn KM, Sherman DR, Klein E, Janssen C, Flynn JL, Andersen P.

J Clin Invest. 2012 Jan;122(1):303-14. doi: 10.1172/JCI46252. Epub 2011 Dec 1.


Interferon release does not add discriminatory value to smear-negative HIV-tuberculosis algorithms.

Rangaka MX, Gideon HP, Wilkinson KA, Pai M, Mwansa-Kambafwile J, Maartens G, Glynn JR, Boulle A, Fielding K, Goliath R, Titus R, Mathee S, Wilkinson RJ.

Eur Respir J. 2012 Jan;39(1):163-71. doi: 10.1183/09031936.00058911. Epub 2011 Jun 30.


Latent tuberculosis: what the host "sees"?

Gideon HP, Flynn JL.

Immunol Res. 2011 Aug;50(2-3):202-12. doi: 10.1007/s12026-011-8229-7. Review.


Immune responses to the enduring hypoxic response antigen Rv0188 are preferentially detected in Mycobacterium bovis infected cattle with low pathology.

Jones GJ, Pirson C, Gideon HP, Wilkinson KA, Sherman DR, Wilkinson RJ, Hewinson RG, Vordermeier HM.

PLoS One. 2011;6(6):e21371. doi: 10.1371/journal.pone.0021371. Epub 2011 Jun 21.


High prevalence of subclinical tuberculosis in HIV-1-infected persons without advanced immunodeficiency: implications for TB screening.

Oni T, Burke R, Tsekela R, Bangani N, Seldon R, Gideon HP, Wood K, Wilkinson KA, Ottenhoff TH, Wilkinson RJ.

Thorax. 2011 Aug;66(8):669-73. doi: 10.1136/thx.2011.160168. Epub 2011 May 31.


Hypoxia induces an immunodominant target of tuberculosis specific T cells absent from common BCG vaccines.

Gideon HP, Wilkinson KA, Rustad TR, Oni T, Guio H, Kozak RA, Sherman DR, Meintjes G, Behr MA, Vordermeier HM, Young DB, Wilkinson RJ.

PLoS Pathog. 2010 Dec 23;6(12):e1001237. doi: 10.1371/journal.ppat.1001237.


Enhanced diagnosis of HIV-1-associated tuberculosis by relating T-SPOT.TB and CD4 counts.

Oni T, Patel J, Gideon HP, Seldon R, Wood K, Hlombe Y, Wilkinson KA, Rangaka MX, Mendelson M, Wilkinson RJ.

Eur Respir J. 2010 Sep;36(3):594-600. doi: 10.1183/09031936.00171509. Epub 2010 Jan 14.


Eliminating latent tuberculosis.

Young DB, Gideon HP, Wilkinson RJ.

Trends Microbiol. 2009 May;17(5):183-8. doi: 10.1016/j.tim.2009.02.005. Epub 2009 Apr 16.


Midwifery practices in rural Punjab, India.

Gordon JE, Gideon H, Wyon JB.

Am J Obstet Gynecol. 1965 Nov 1;93(5):734-42. No abstract available.


[Traditional obstetrics in rural regions].

Gordon JE, Gideon H, Wyon JB.

Bol Oficina Sanit Panam. 1965 Oct;59(4):313-24. Spanish. No abstract available.


Asymptomatic infections in leprosy.

Taylor CE, Elliston EP, Gideon H.

Int J Lepr. 1965 Jul-Sep;33(3):Suppl:716-31. No abstract available.




Am J Med Sci. 1964 Mar;247:344-62. No abstract available.


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