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Items: 26

1.

Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans.

Finan B, Ma T, Ottaway N, Müller TD, Habegger KM, Heppner KM, Kirchner H, Holland J, Hembree J, Raver C, Lockie SH, Smiley DL, Gelfanov V, Yang B, Hofmann S, Bruemmer D, Drucker DJ, Pfluger PT, Perez-Tilve D, Gidda J, Vignati L, Zhang L, Hauptman JB, Lau M, Brecheisen M, Uhles S, Riboulet W, Hainaut E, Sebokova E, Conde-Knape K, Konkar A, DiMarchi RD, Tschöp MH.

Sci Transl Med. 2013 Oct 30;5(209):209ra151. doi: 10.1126/scitranslmed.3007218.

2.

Optimization of co-agonism at GLP-1 and glucagon receptors to safely maximize weight reduction in DIO-rodents.

Day JW, Gelfanov V, Smiley D, Carrington PE, Eiermann G, Chicchi G, Erion MD, Gidda J, Thornberry NA, Tschöp MH, Marsh DJ, SinhaRoy R, DiMarchi R, Pocai A.

Biopolymers. 2012;98(5):443-50. doi: 10.1002/bip.22072.

PMID:
23203689
3.

A new glucagon and GLP-1 co-agonist eliminates obesity in rodents.

Day JW, Ottaway N, Patterson JT, Gelfanov V, Smiley D, Gidda J, Findeisen H, Bruemmer D, Drucker DJ, Chaudhary N, Holland J, Hembree J, Abplanalp W, Grant E, Ruehl J, Wilson H, Kirchner H, Lockie SH, Hofmann S, Woods SC, Nogueiras R, Pfluger PT, Perez-Tilve D, DiMarchi R, Tschöp MH.

Nat Chem Biol. 2009 Oct;5(10):749-57. doi: 10.1038/nchembio.209. Epub 2009 Jul 13.

PMID:
19597507
4.

Syntheses and antifungal activities of novel 3-amido bearing pseudomycin analogues.

Zhang YZ, Sun X, Zeckner DJ, Sachs RK, Current WL, Gidda J, Rodriguez M, Chen SH.

Bioorg Med Chem Lett. 2001 Apr 9;11(7):903-7.

PMID:
11294388
5.

Pharmacology of butylthio[2.2.2] (LY297802/NNC11-1053): a novel analgesic with mixed muscarinic receptor agonist and antagonist activity.

Shannon HE, Sheardown MJ, Bymaster FP, Calligaro DO, Delapp NW, Gidda J, Mitch CH, Sawyer BD, Stengel PW, Ward JS, Wong DT, Olesen PH, Suzdak PD, Sauerberg P, Swedberg MD.

J Pharmacol Exp Ther. 1997 May;281(2):884-94.

PMID:
9152398
6.

Antagonism of serotonin3 (5-HT3) receptors within the blood-brain barrier prevents cisplatin-induced emesis in dogs.

Gidda JS, Evans DC, Cohen ML, Wong DT, Robertson DW, Parli CJ.

J Pharmacol Exp Ther. 1995 May;273(2):695-701.

PMID:
7752072
7.

Discovery of a potent, peripherally selective trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine opioid antagonist for the treatment of gastrointestinal motility disorders.

Zimmerman DM, Gidda JS, Cantrell BE, Schoepp DD, Johnson BG, Leander JD.

J Med Chem. 1994 Jul 22;37(15):2262-5.

PMID:
8057274
8.

Effects of LY267108, an erythromycin analogue derivative, on lower esophageal sphincter function in the cat.

Greenwood B, Dieckman D, Kirst HA, Gidda JS.

Gastroenterology. 1994 Mar;106(3):624-8.

PMID:
8119532
9.

Effect of zatosetron on ipecac-induced emesis in dogs and healthy men.

Schwartz SM, Goldberg MJ, Gidda JS, Cerimele BJ.

J Clin Pharmacol. 1994 Mar;34(3):250-4.

PMID:
7517409
10.

LY277359 maleate: a potent and selective 5-HT3 receptor antagonist without gastroprokinetic activity.

Cohen ML, Bloomquist W, Gidda JS, Lacefield W.

J Pharmacol Exp Ther. 1990 Jul;254(1):350-5.

PMID:
2366187
11.

Preclinical studies on quinelorane, a potent and highly selective D2-dopaminergic agonist.

Foreman MM, Fuller RW, Hynes MD, Gidda JS, Nichols CL, Schaus JM, Kornfeld EC, Clemens JA.

J Pharmacol Exp Ther. 1989 Jul;250(1):227-35.

PMID:
2526214
12.

General pharmacology of nizatidine in animals.

Bemis K, Bendele A, Clemens J, Deldar A, Gidda J, Hamelink J, Holland D, Lamishaw B, McGrath J, Shannon H, et al.

Arzneimittelforschung. 1989 Feb;39(2):240-50.

PMID:
2567169
13.

Comparison of the 5-HT3 receptor antagonist properties of ICS 205-930, GR38032F and zacopride.

Cohen ML, Bloomquist W, Gidda JS, Lacefield W.

J Pharmacol Exp Ther. 1989 Jan;248(1):197-201.

PMID:
2521513
14.

Swallow-evoked peristalsis in opossum esophagus: role of cholinergic mechanisms.

Gidda JS, Buyniski JP.

Am J Physiol. 1986 Dec;251(6 Pt 1):G779-85.

PMID:
3789145
15.

Role of substance P nerves in longitudinal smooth muscle contractions of the esophagus.

Crist J, Gidda J, Goyal RK.

Am J Physiol. 1986 Mar;250(3 Pt 1):G336-43.

PMID:
2420208
16.

Regional gradient of initial inhibition and refractoriness in esophageal smooth muscle.

Gidda JS, Goyal RK.

Gastroenterology. 1985 Oct;89(4):843-51.

PMID:
4029565
17.

Swallow-evoked action potentials in vagal preganglionic efferents.

Gidda JS, Goyal RK.

J Neurophysiol. 1984 Dec;52(6):1169-80.

PMID:
6520630
18.

Intramural mechanism of esophageal peristalsis: roles of cholinergic and noncholinergic nerves.

Crist J, Gidda JS, Goyal RK.

Proc Natl Acad Sci U S A. 1984 Jun;81(11):3595-9.

19.

Acetylcholinesterase and choline acetyltransferase staining of neurons in the opossum esophagus.

Seelig LL Jr, Doody P, Brainard L, Gidda JS, Goyal RK.

Anat Rec. 1984 May;209(1):125-30.

PMID:
6203439
20.

Characteristics of "on" and "off" contractions in esophageal circular muscle in vitro.

Crist J, Gidda JS, Goyal RK.

Am J Physiol. 1984 Feb;246(2 Pt 1):G137-44.

PMID:
6696110
21.

Membrane potential and mechanical responses of the opossum esophagus to vagal stimulation and swallowing.

Rattan S, Gidda JS, Goyal RK.

Gastroenterology. 1983 Oct;85(4):922-8.

PMID:
6884715
22.
23.

Modulation of esophageal peristalsis by vagal efferent stimulation in opossum.

Gidda JS, Cobb BW, Goyal RK.

J Clin Invest. 1981 Dec;68(6):1411-9.

24.

Relation between electrical and mechanical activity in esophageal smooth muscle.

Goyal RK, Gidda JS.

Am J Physiol. 1981 Apr;240(4):G305-11.

PMID:
7223895
25.

Influence of vagus nerves on electrical activity of opossum small intestine.

Gidda JS, Goyal RK.

Am J Physiol. 1980 Nov;239(5):G406-10.

PMID:
7435632
26.

Functional characteristics of superior olivary neurons to binaural stimuli.

Moushegian G, Rupert AL, Gidda JS.

J Neurophysiol. 1975 Sep;38(5):1037-48.

PMID:
1177003

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