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Prevotella histicola, A Human Gut Commensal, Is as Potent as COPAXONE® in an Animal Model of Multiple Sclerosis.

Shahi SK, Freedman SN, Murra AC, Zarei K, Sompallae R, Gibson-Corley KN, Karandikar NJ, Murray JA, Mangalam AK.

Front Immunol. 2019 Mar 22;10:462. doi: 10.3389/fimmu.2019.00462. eCollection 2019.


In utero and postnatal VX-770 administration rescues multiorgan disease in a ferret model of cystic fibrosis.

Sun X, Yi Y, Yan Z, Rosen BH, Liang B, Winter MC, Evans TIA, Rotti PG, Yang Y, Gray JS, Park SY, Zhou W, Zhang Y, Moll SR, Woody L, Tran DM, Jiang L, Vonk AM, Beekman JM, Negulescu P, Van Goor F, Fiorino DF, Gibson-Corley KN, Engelhardt JF.

Sci Transl Med. 2019 Mar 27;11(485). pii: eaau7531. doi: 10.1126/scitranslmed.aau7531.


Interleukin-1 alpha increases anti-tumor efficacy of cetuximab in head and neck squamous cell carcinoma.

Espinosa-Cotton M, Rodman Iii SN, Ross KA, Jensen IJ, Sangodeyi-Miller K, McLaren AJ, Dahl RA, Gibson-Corley KN, Koch AT, Fu YX, Badovinac VP, Laux D, Narasimhan B, Simons AL.

J Immunother Cancer. 2019 Mar 19;7(1):79. doi: 10.1186/s40425-019-0550-z.


Incretin dysfunction and hyperglycemia in cystic fibrosis: Role of acyl-ghrelin.

Sun X, Yi Y, Liang B, Yang Y, He N, Ode KL, Uc A, Wang K, Gibson-Corley KN, Engelhardt JF, Norris AW.

J Cyst Fibros. 2019 Feb 6. pii: S1569-1993(19)30016-5. doi: 10.1016/j.jcf.2019.01.010. [Epub ahead of print]


Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice.

Sandgren JA, Deng G, Linggonegoro DW, Scroggins SM, Perschbacher KJ, Nair AR, Nishimura TE, Zhang SY, Agbor LN, Wu J, Keen HL, Naber MC, Pearson NA, Zimmerman KA, Weiss RM, Bowdler NC, Usachev YM, Santillan DA, Potthoff MJ, Pierce GL, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL.

JCI Insight. 2018 Oct 4;3(19). pii: 99403. doi: 10.1172/jci.insight.99403.


Observational Study Design in Veterinary Pathology, Part 2: Methodology.

Caswell JL, Bassel LL, Rothenburger JL, Gröne A, Sargeant JM, Beck AP, Ekman S, Gibson-Corley KN, Kuiken T, LaDouceur EEB, Meyerholz DK, Origgi FC, Posthaus H, Priestnall SL, Ressel L, Sharkey L, Teixeira LBC, Uchida K, Ward JM, Webster JD, Yamate J.

Vet Pathol. 2018 Nov;55(6):774-785. doi: 10.1177/0300985818798121. Epub 2018 Sep 18.


Observational Study Design in Veterinary Pathology, Part 1: Study Design.

Caswell JL, Bassel LL, Rothenburger JL, Gröne A, Sargeant JM, Beck AP, Ekman S, Gibson-Corley KN, Kuiken T, LaDouceur EEB, Meyerholz DK, Origgi FC, Posthaus H, Priestnall SL, Ressel L, Sharkey L, Teixeira LBC, Uchida K, Ward JM, Webster JD, Yamate J.

Vet Pathol. 2018 Sep;55(5):607-621. doi: 10.1177/0300985818785705. Epub 2018 Aug 2.


Regulators of G protein signaling in cardiovascular function during pregnancy.

Perschbacher KJ, Deng G, Fisher RA, Gibson-Corley KN, Santillan MK, Grobe JL.

Physiol Genomics. 2018 Aug 1;50(8):590-604. doi: 10.1152/physiolgenomics.00037.2018. Epub 2018 Apr 27.


PCB126 Inhibits the Activation of AMPK-CREB Signal Transduction Required for Energy Sensing in Liver.

Gadupudi GS, Elser BA, Sandgruber FA, Li X, Gibson-Corley KN, Robertson LW.

Toxicol Sci. 2018 Jun 1;163(2):440-453. doi: 10.1093/toxsci/kfy041.


Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs.

Meyerholz DK, Stoltz DA, Gansemer ND, Ernst SE, Cook DP, Strub MD, LeClair EN, Barker CK, Adam RJ, Leidinger MR, Gibson-Corley KN, Karp PH, Welsh MJ, McCray PB Jr.

Lab Invest. 2018 Jun;98(6):825-838. doi: 10.1038/s41374-018-0026-7. Epub 2018 Feb 21.


Pharmacologic ascorbate (P-AscH-) suppresses hypoxia-inducible Factor-1α (HIF-1α) in pancreatic adenocarcinoma.

Wilkes JG, O'Leary BR, Du J, Klinger AR, Sibenaller ZA, Doskey CM, Gibson-Corley KN, Alexander MS, Tsai S, Buettner GR, Cullen JJ.

Clin Exp Metastasis. 2018 Feb;35(1-2):37-51. doi: 10.1007/s10585-018-9876-z. Epub 2018 Feb 2.


Elevated vasopressin in pregnant mice induces T-helper subset alterations consistent with human preeclampsia.

Scroggins SM, Santillan DA, Lund JM, Sandgren JA, Krotz LK, Hamilton WS, Devor EJ, Davis HA, Pierce GL, Gibson-Corley KN, Sigmund CD, Grobe JL, Santillan MK.

Clin Sci (Lond). 2018 Feb 14;132(3):419-436. doi: 10.1042/CS20171059. Print 2018 Feb 14.


Lipopolysaccharide-induced maternal inflammation induces direct placental injury without alteration in placental blood flow and induces a secondary fetal intestinal injury that persists into adulthood.

Fricke EM, Elgin TG, Gong H, Reese J, Gibson-Corley KN, Weiss RM, Zimmerman K, Bowdler NC, Kalantera KM, Mills DA, Underwood MA, McElroy SJ.

Am J Reprod Immunol. 2018 May;79(5):e12816. doi: 10.1111/aji.12816. Epub 2018 Jan 25.


Pancreatic and Islet Remodeling in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Knockout Ferrets.

Rotti PG, Xie W, Poudel A, Yi Y, Sun X, Tyler SR, Uc A, Norris AW, Hara M, Engelhardt JF, Gibson-Corley KN.

Am J Pathol. 2018 Apr;188(4):876-890. doi: 10.1016/j.ajpath.2017.12.015. Epub 2018 Jan 31.


Angiotensin AT1A receptors expressed in vasopressin-producing cells of the supraoptic nucleus contribute to osmotic control of vasopressin.

Sandgren JA, Linggonegoro DW, Zhang SY, Sapouckey SA, Claflin KE, Pearson NA, Leidinger MR, Pierce GL, Santillan MK, Gibson-Corley KN, Sigmund CD, Grobe JL.

Am J Physiol Regul Integr Comp Physiol. 2018 Jun 1;314(6):R770-R780. doi: 10.1152/ajpregu.00435.2017. Epub 2018 Jan 24.


Effects of excess thromboxane A2 on placental development and nutrient transporters in a Mus musculus model of fetal growth restriction.

Gibbins KJ, Gibson-Corley KN, Brown AS, Wieben M, Law RC, Fung CM.

Biol Reprod. 2018 May 1;98(5):695-704. doi: 10.1093/biolre/ioy006.


Infection Is Not Required for Mucoinflammatory Lung Disease in CFTR-Knockout Ferrets.

Rosen BH, Evans TIA, Moll SR, Gray JS, Liang B, Sun X, Zhang Y, Jensen-Cody CW, Swatek AM, Zhou W, He N, Rotti PG, Tyler SR, Keiser NW, Anderson PJ, Brooks L, Li Y, Pope RM, Rajput M, Hoffman EA, Wang K, Harris JK, Parekh KR, Gibson-Corley KN, Engelhardt JF.

Am J Respir Crit Care Med. 2018 May 15;197(10):1308-1318. doi: 10.1164/rccm.201708-1616OC.


Nlrp12 Mediates Adverse Neutrophil Recruitment during Influenza Virus Infection.

Hornick EE, Banoth B, Miller AM, Zacharias ZR, Jain N, Wilson ME, Gibson-Corley KN, Legge KL, Bishop GA, Sutterwala FS, Cassel SL.

J Immunol. 2018 Feb 1;200(3):1188-1197. doi: 10.4049/jimmunol.1700999. Epub 2017 Dec 27.


The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity.

Rauckhorst AJ, Gray LR, Sheldon RD, Fu X, Pewa AD, Feddersen CR, Dupuy AJ, Gibson-Corley KN, Cox JE, Burgess SC, Taylor EB.

Mol Metab. 2017 Nov;6(11):1468-1479. doi: 10.1016/j.molmet.2017.09.002. Epub 2017 Sep 18.


Leishmania-Derived Trimannose Modulates the Inflammatory Response To Significantly Reduce Leishmania major-Induced Lesions.

Grinnage-Pulley TL, Kabotso DEK, Rintelmann CL, Roychoudhury R, Schaut RG, Toepp AJ, Gibson-Corley KN, Parrish M, Pohl NLB, Petersen CA.

Infect Immun. 2017 Dec 19;86(1). pii: e00672-17. doi: 10.1128/IAI.00672-17. Print 2018 Jan.


Suppression of autoimmune demyelinating disease by preferential stimulation of CNS-specific CD8 T cells using Listeria-encoded neuroantigen.

Itani FR, Sinha S, Brate AA, Pewe LL, Gibson-Corley KN, Harty JT, Karandikar NJ.

Sci Rep. 2017 May 8;7(1):1519. doi: 10.1038/s41598-017-01771-8.


Angiotensin AT1A receptors on leptin receptor-expressing cells control resting metabolism.

Claflin KE, Sandgren JA, Lambertz AM, Weidemann BJ, Littlejohn NK, Burnett CM, Pearson NA, Morgan DA, Gibson-Corley KN, Rahmouni K, Grobe JL.

J Clin Invest. 2017 Apr 3;127(4):1414-1424. doi: 10.1172/JCI88641. Epub 2017 Mar 6.


An ovine model of spinal cord injury.

Wilson S, Abode-Iyamah KO, Miller JW, Reddy CG, Safayi S, Fredericks DC, Jeffery ND, DeVries-Watson NA, Shivapour SK, Viljoen S, Dalm BD, Gibson-Corley KN, Johnson MD, Gillies GT, Howard MA 3rd.

J Spinal Cord Med. 2017 May;40(3):346-360. doi: 10.1080/10790268.2016.1222475. Epub 2016 Oct 19.


Interleukin-1 blockade overcomes erlotinib resistance in head and neck squamous cell carcinoma.

Stanam A, Gibson-Corley KN, Love-Homan L, Ihejirika N, Simons AL.

Oncotarget. 2016 Nov 15;7(46):76087-76100. doi: 10.18632/oncotarget.12590.


Assessment of the Mitigative Capacity of Dietary Zinc on PCB126 Hepatotoxicity and the Contribution of Zinc to Toxicity.

Klaren WD, Gibson-Corley KN, Wels B, Simmons DL, McCormick ML, Spitz DR, Robertson LW.

Chem Res Toxicol. 2016 May 16;29(5):851-9. doi: 10.1021/acs.chemrestox.6b00022. Epub 2016 Mar 23.


TRAF2 exerts opposing effects on basal and TNFα-induced activation of the classic IKK complex in hematopoietic cells in mice.

Zhang L, Blackwell K, Workman LM, Gibson-Corley KN, Olivier AK, Bishop GA, Habelhah H.

J Cell Sci. 2016 Apr 1;129(7):1455-67. doi: 10.1242/jcs.180554. Epub 2016 Feb 12.


A method for histopathological study of the multifocal nature of spinal cord lesions in murine experimental autoimmune encephalomyelitis.

Gibson-Corley KN, Boyden AW, Leidinger MR, Lambertz AM, Ofori-Amanfo G, Naumann PW, Goeken JA, Karandikar NJ.

PeerJ. 2016 Jan 26;4:e1600. doi: 10.7717/peerj.1600. eCollection 2016.


Metallothionein's role in PCB126 induced hepatotoxicity and hepatic micronutrient disruption.

Klaren WD, Flor S, Gibson-Corley KN, Ludewig G, Robertson LW.

Toxicol Rep. 2016;3:21-28.


Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4.

Li K, Wohlford-Lenane C, Perlman S, Zhao J, Jewell AK, Reznikov LR, Gibson-Corley KN, Meyerholz DK, McCray PB Jr.

J Infect Dis. 2016 Mar 1;213(5):712-22. doi: 10.1093/infdis/jiv499. Epub 2015 Oct 20.


Effects of prenatal inhalation exposure to copper nanoparticles on murine dams and offspring.

Adamcakova-Dodd A, Monick MM, Powers LS, Gibson-Corley KN, Thorne PS.

Part Fibre Toxicol. 2015 Oct 6;12:30. doi: 10.1186/s12989-015-0105-5.


Pancreatic pathophysiology in cystic fibrosis.

Gibson-Corley KN, Meyerholz DK, Engelhardt JF.

J Pathol. 2016 Jan;238(2):311-20. doi: 10.1002/path.4634. Epub 2015 Oct 1. Review.


FBG1 Is the Final Arbitrator of A1AT-Z Degradation.

Wen JH, Wen H, Gibson-Corley KN, Glenn KA.

PLoS One. 2015 Aug 21;10(8):e0135591. doi: 10.1371/journal.pone.0135591. eCollection 2015.


Vasopressin: the missing link for preeclampsia?

Sandgren JA, Scroggins SM, Santillan DA, Devor EJ, Gibson-Corley KN, Pierce GL, Sigmund CD, Santillan MK, Grobe JL.

Am J Physiol Regul Integr Comp Physiol. 2015 Nov 1;309(9):R1062-4. doi: 10.1152/ajpregu.00073.2015. Epub 2015 Mar 25. Review.


Pregnant mice lacking indoleamine 2,3-dioxygenase exhibit preeclampsia phenotypes.

Santillan MK, Pelham CJ, Ketsawatsomkron P, Santillan DA, Davis DR, Devor EJ, Gibson-Corley KN, Scroggins SM, Grobe JL, Yang B, Hunter SK, Sigmund CD.

Physiol Rep. 2015 Jan 19;3(1). pii: e12257. doi: 10.14814/phy2.12257. Print 2015 Jan 1.


Animal models of gastrointestinal and liver diseases. Animal models of cystic fibrosis: gastrointestinal, pancreatic, and hepatobiliary disease and pathophysiology.

Olivier AK, Gibson-Corley KN, Meyerholz DK.

Am J Physiol Gastrointest Liver Physiol. 2015 Mar 15;308(6):G459-71. doi: 10.1152/ajpgi.00146.2014. Epub 2015 Jan 15. Review.


Immunohistochemical detection of arginase-I expression in formalin-fixed lung and other tissues.

Hochstedler CM, Leidinger MR, Maher-Sturm MT, Gibson-Corley KN, Meyerholz DK.

J Histotechnol. 2013 Dec;36(4):128-134.


Keratoacanthoma Pathobiology in Mouse Models.

Gibson-Corley KN, Rogers LM, Goeken A, Dupuy AJ, Meyerholz DK.

Diseases. 2014 May 23;2(2):106-119.


An in vitro model of antibody-enhanced killing of the intracellular parasite Leishmania amazonensis.

Gibson-Corley KN, Bockenstedt MM, Li H, Boggiatto PM, Phanse Y, Petersen CA, Bellaire BH, Jones DE.

PLoS One. 2014 Sep 5;9(9):e106426. doi: 10.1371/journal.pone.0106426. eCollection 2014.


Vasopressin in preeclampsia: a novel very early human pregnancy biomarker and clinically relevant mouse model.

Santillan MK, Santillan DA, Scroggins SM, Min JY, Sandgren JA, Pearson NA, Leslie KK, Hunter SK, Zamba GK, Gibson-Corley KN, Grobe JL.

Hypertension. 2014 Oct;64(4):852-9. doi: 10.1161/HYPERTENSIONAHA.114.03848. Epub 2014 Jul 7. Erratum in: Hypertension. 2015 Mar;65(3):e9.


Development of a poly (lactic-co-glycolic acid) particle vaccine to protect against house dust mite induced allergy.

Joshi VB, Adamcakova-Dodd A, Jing X, Wongrakpanich A, Gibson-Corley KN, Thorne PS, Salem AK.

AAPS J. 2014 Sep;16(5):975-85. doi: 10.1208/s12248-014-9624-5. Epub 2014 Jul 1.


Postsurgical pathologies associated with intradural electrical stimulation in the central nervous system: design implications for a new clinical device.

Gibson-Corley KN, Flouty O, Oya H, Gillies GT, Howard MA.

Biomed Res Int. 2014;2014:989175. doi: 10.1155/2014/989175. Epub 2014 Apr 1. Review.


G-protein coupled receptor expression patterns delineate medulloblastoma subgroups.

Whittier KL, Boese EA, Gibson-Corley KN, Kirby PA, Darbro BW, Qian Q, Ingram WJ, Robertson T, Remke M, Taylor MD, O'Dorisio MS.

Acta Neuropathol Commun. 2013 Oct 10;1:66. doi: 10.1186/2051-5960-1-66.


Integrin α3β1 can function to promote spontaneous metastasis and lung colonization of invasive breast carcinoma.

Zhou B, Gibson-Corley KN, Herndon ME, Sun Y, Gustafson-Wagner E, Teoh-Fitzgerald M, Domann FE, Henry MD, Stipp CS.

Mol Cancer Res. 2014 Jan;12(1):143-154. doi: 10.1158/1541-7786.MCR-13-0184. Epub 2013 Sep 3.


The Justy mutant mouse strain produces a spontaneous murine model of salivary gland cancer with myoepithelial and basal cell differentiation.

Simons AL, Lu P, Gibson-Corley KN, Robinson RA, Meyerholz DK, Colgan JD.

Lab Invest. 2013 Jun;93(6):711-9. doi: 10.1038/labinvest.2013.62. Epub 2013 Apr 22.


Principles for valid histopathologic scoring in research.

Gibson-Corley KN, Olivier AK, Meyerholz DK.

Vet Pathol. 2013 Nov;50(6):1007-15. doi: 10.1177/0300985813485099. Epub 2013 Apr 4. Review.


Intracranial somatosensory responses with direct spinal cord stimulation in anesthetized sheep.

Flouty OE, Oya H, Kawasaki H, Reddy CG, Fredericks DC, Gibson-Corley KN, Jeffery ND, Gillies GT, Howard MA 3rd.

PLoS One. 2013;8(2):e56266. doi: 10.1371/journal.pone.0056266. Epub 2013 Feb 15.


Ovine tests of a novel spinal cord neuromodulator and dentate ligament fixation method.

Gibson-Corley KN, Oya H, Flouty O, Fredericks DC, Jeffery ND, Gillies GT, Howard MA 3rd.

J Invest Surg. 2012 Dec;25(6):366-74. doi: 10.3109/08941939.2012.677967.


A new device concept for directly modulating spinal cord pathways: initial in vivo experimental results.

Flouty O, Oya H, Kawasaki H, Wilson S, Reddy CG, Jeffery ND, Brennan TJ, Gibson-Corley KN, Utz M, Gillies GT, Howard MA 3rd.

Physiol Meas. 2012 Dec;33(12):2003-15. doi: 10.1088/0967-3334/33/12/2003. Epub 2012 Nov 15.


Genetically modified species in research: Opportunities and challenges for the histology core laboratory.

Olivier AK, Naumann P, Goeken A, Hochstedler C, Sturm M, Rodgers JR, Gibson-Corley KN, Meyerholz DK.

J Histotechnol. 2012 Jul 1;35(2):63-67.


Successful Integration of the Histology Core Laboratory in Translational Research.

Gibson-Corley KN, Hochstedler C, Sturm M, Rogers J, Olivier AK, Meyerholz DK.

J Histotechnol. 2012 Apr 1;35(1):17-21.

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