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Items: 1 to 50 of 231

1.

Proteome and Secretome Dynamics of Human Retinal Pigment Epithelium in Response to Reactive Oxygen Species.

Meyer JG, Garcia TY, Schilling B, Gibson BW, Lamba DA.

Sci Rep. 2019 Oct 28;9(1):15440. doi: 10.1038/s41598-019-51777-7.

2.

Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins.

Softic S, Meyer JG, Wang GX, Gupta MK, Batista TM, Lauritzen HPMM, Fujisaka S, Serra D, Herrero L, Willoughby J, Fitzgerald K, Ilkayeva O, Newgard CB, Gibson BW, Schilling B, Cohen DE, Kahn CR.

Cell Metab. 2019 Oct 1;30(4):735-753.e4. doi: 10.1016/j.cmet.2019.09.003.

PMID:
31577934
3.

SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells.

Wiley CD, Liu S, Limbad C, Zawadzka AM, Beck J, Demaria M, Artwood R, Alimirah F, Lopez-Dominguez JA, Kuehnemann C, Danielson SR, Basisty N, Kasler HG, Oron TR, Desprez PY, Mooney SD, Gibson BW, Schilling B, Campisi J, Kapahi P.

Cell Rep. 2019 Sep 24;28(13):3329-3337.e5. doi: 10.1016/j.celrep.2019.08.049.

4.

JNK modifies neuronal metabolism to promote proteostasis and longevity.

Wang L, Davis SS, Borch Jensen M, Rodriguez-Fernandez IA, Apaydin C, Juhasz G, Gibson BW, Schilling B, Ramanathan A, Ghaemmaghami S, Jasper H.

Aging Cell. 2019 Jun;18(3):e12849. doi: 10.1111/acel.12849. Epub 2019 Feb 27.

5.

Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose.

Meyer JG, Softic S, Basisty N, Rardin MJ, Verdin E, Gibson BW, Ilkayeva O, Newgard CB, Kahn CR, Schilling B.

PLoS One. 2018 Dec 26;13(12):e0208973. doi: 10.1371/journal.pone.0208973. eCollection 2018.

6.

Simultaneous Quantification of the Acetylome and Succinylome by 'One-Pot' Affinity Enrichment.

Basisty N, Meyer JG, Wei L, Gibson BW, Schilling B.

Proteomics. 2018 Sep;18(17):e1800123. doi: 10.1002/pmic.201800123. Epub 2018 Aug 19.

7.

The Mitochondrial Acylome Emerges: Proteomics, Regulation by Sirtuins, and Metabolic and Disease Implications.

Carrico C, Meyer JG, He W, Gibson BW, Verdin E.

Cell Metab. 2018 Mar 6;27(3):497-512. doi: 10.1016/j.cmet.2018.01.016. Review.

8.

An acetylatable lysine controls CRP function in E. coli.

Davis R, Écija-Conesa A, Gallego-Jara J, de Diego T, Filippova EV, Kuffel G, Anderson WF, Gibson BW, Schilling B, Canovas M, Wolfe AJ.

Mol Microbiol. 2018 Jan;107(1):116-131. doi: 10.1111/mmi.13874. Epub 2017 Nov 23.

9.

Characterization of Inner and Outer Membrane Proteins from Francisella tularensis Strains LVS and Schu S4 and Identification of Potential Subunit Vaccine Candidates.

Post DMB, Slütter B, Schilling B, Chande AT, Rasmussen JA, Jones BD, D'Souza AK, Reinders LM, Harty JT, Gibson BW, Apicella MA.

MBio. 2017 Oct 10;8(5). pii: e01592-17. doi: 10.1128/mBio.01592-17.

10.

Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry.

Collins BC, Hunter CL, Liu Y, Schilling B, Rosenberger G, Bader SL, Chan DW, Gibson BW, Gingras AC, Held JM, Hirayama-Kurogi M, Hou G, Krisp C, Larsen B, Lin L, Liu S, Molloy MP, Moritz RL, Ohtsuki S, Schlapbach R, Selevsek N, Thomas SN, Tzeng SC, Zhang H, Aebersold R.

Nat Commun. 2017 Aug 21;8(1):291. doi: 10.1038/s41467-017-00249-5.

11.

PIQED: automated identification and quantification of protein modifications from DIA-MS data.

Meyer JG, Mukkamalla S, Steen H, Nesvizhskii AI, Gibson BW, Schilling B.

Nat Methods. 2017 Jun 29;14(7):646-647. doi: 10.1038/nmeth.4334. No abstract available.

12.

Identification and characterization of AckA-dependent protein acetylation in Neisseria gonorrhoeae.

Post DMB, Schilling B, Reinders LM, D'Souza AK, Ketterer MR, Kiel SJ, Chande AT, Apicella MA, Gibson BW.

PLoS One. 2017 Jun 27;12(6):e0179621. doi: 10.1371/journal.pone.0179621. eCollection 2017.

13.

Lysine desuccinylase SIRT5 binds to cardiolipin and regulates the electron transport chain.

Zhang Y, Bharathi SS, Rardin MJ, Lu J, Maringer KV, Sims-Lucas S, Prochownik EV, Gibson BW, Goetzman ES.

J Biol Chem. 2017 Jun 16;292(24):10239-10249. doi: 10.1074/jbc.M117.785022. Epub 2017 Apr 30.

14.

Generation of High-Quality SWATH® Acquisition Data for Label-free Quantitative Proteomics Studies Using TripleTOF® Mass Spectrometers.

Schilling B, Gibson BW, Hunter CL.

Methods Mol Biol. 2017;1550:223-233. doi: 10.1007/978-1-4939-6747-6_16.

15.

MiR-590 Promotes Transdifferentiation of Porcine and Human Fibroblasts Toward a Cardiomyocyte-Like Fate by Directly Repressing Specificity Protein 1.

Singh VP, Mathison M, Patel V, Sanagasetti D, Gibson BW, Yang J, Rosengart TK.

J Am Heart Assoc. 2016 Nov 10;5(11). pii: e003922.

16.

Vitamin D Promotes Protein Homeostasis and Longevity via the Stress Response Pathway Genes skn-1, ire-1, and xbp-1.

Mark KA, Dumas KJ, Bhaumik D, Schilling B, Davis S, Oron TR, Sorensen DJ, Lucanic M, Brem RB, Melov S, Ramanathan A, Gibson BW, Lithgow GJ.

Cell Rep. 2016 Oct 25;17(5):1227-1237. doi: 10.1016/j.celrep.2016.09.086.

17.

Quantification of Lysine Acetylation and Succinylation Stoichiometry in Proteins Using Mass Spectrometric Data-Independent Acquisitions (SWATH).

Meyer JG, D'Souza AK, Sorensen DJ, Rardin MJ, Wolfe AJ, Gibson BW, Schilling B.

J Am Soc Mass Spectrom. 2016 Nov;27(11):1758-1771. Epub 2016 Sep 2.

18.

Gadd45a Protein Promotes Skeletal Muscle Atrophy by Forming a Complex with the Protein Kinase MEKK4.

Bullard SA, Seo S, Schilling B, Dyle MC, Dierdorff JM, Ebert SM, DeLau AD, Gibson BW, Adams CM.

J Biol Chem. 2016 Aug 19;291(34):17496-17509. doi: 10.1074/jbc.M116.740308. Epub 2016 Jun 29.

19.

Comparative Analyses of the Lipooligosaccharides from Nontypeable Haemophilus influenzae and Haemophilus haemolyticus Show Differences in Sialic Acid and Phosphorylcholine Modifications.

Post DM, Ketterer MR, Coffin JE, Reinders LM, Munson RS Jr, Bair T, Murphy TF, Foster ED, Gibson BW, Apicella MA.

Infect Immun. 2016 Jan 4;84(3):765-74. doi: 10.1128/IAI.01185-15.

20.

Risk Factors for Anticipatory Grief in Family Members of Terminally Ill Veterans Receiving Palliative Care Services.

Burke LA, Clark KA, Ali KS, Gibson BW, Smigelsky MA, Neimeyer RA.

J Soc Work End Life Palliat Care. 2015;11(3-4):244-66. doi: 10.1080/15524256.2015.1110071.

PMID:
26654060
21.

Multiplexed, Scheduled, High-Resolution Parallel Reaction Monitoring on a Full Scan QqTOF Instrument with Integrated Data-Dependent and Targeted Mass Spectrometric Workflows.

Schilling B, MacLean B, Held JM, Sahu AK, Rardin MJ, Sorensen DJ, Peters T, Wolfe AJ, Hunter CL, MacCoss MJ, Gibson BW.

Anal Chem. 2015 Oct 20;87(20):10222-9. doi: 10.1021/acs.analchem.5b02983. Epub 2015 Sep 30.

22.

Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.

Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, Minami SS, Defensor E, Mok SA, Sohn PD, Schilling B, Cong X, Ellerby L, Gibson BW, Johnson J, Krogan N, Shamloo M, Gestwicki J, Masliah E, Verdin E, Gan L.

Nat Med. 2015 Oct;21(10):1154-62. doi: 10.1038/nm.3951. Epub 2015 Sep 21.

23.

Protein acetylation dynamics in response to carbon overflow in Escherichia coli.

Schilling B, Christensen D, Davis R, Sahu AK, Hu LI, Walker-Peddakotla A, Sorensen DJ, Zemaitaitis B, Gibson BW, Wolfe AJ.

Mol Microbiol. 2015 Dec;98(5):847-63. doi: 10.1111/mmi.13161. Epub 2015 Sep 10.

24.

Comparison of Cesium-137 and X-ray Irradiators by Using Bone Marrow Transplant Reconstitution in C57BL/6J Mice.

Gibson BW, Boles NC, Souroullas GP, Herron AJ, Fraley JK, Schwiebert RS, Sharp JJ, Goodell MA.

Comp Med. 2015 Jun;65(3):165-72.

25.

SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target.

Nishida Y, Rardin MJ, Carrico C, He W, Sahu AK, Gut P, Najjar R, Fitch M, Hellerstein M, Gibson BW, Verdin E.

Mol Cell. 2015 Jul 16;59(2):321-32. doi: 10.1016/j.molcel.2015.05.022. Epub 2015 Jun 11.

26.

Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo.

O'Brien R, DeGiacomo F, Holcomb J, Bonner A, Ring KL, Zhang N, Zafar K, Weiss A, Lager B, Schilling B, Gibson BW, Chen S, Kwak S, Ellerby LM.

J Biol Chem. 2015 Jul 31;290(31):19287-306. doi: 10.1074/jbc.M114.623561. Epub 2015 May 29.

27.

SIRT1 deacetylates RORγt and enhances Th17 cell generation.

Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, Xiao C, Littman DR, Ott M, Verdin E.

J Exp Med. 2015 Jun 1;212(6):973. doi: 10.1084/jem.2013237805062015c. Epub 2015 May 18. No abstract available.

28.

MS1 Peptide Ion Intensity Chromatograms in MS2 (SWATH) Data Independent Acquisitions. Improving Post Acquisition Analysis of Proteomic Experiments.

Rardin MJ, Schilling B, Cheng LY, MacLean BX, Sorensen DJ, Sahu AK, MacCoss MJ, Vitek O, Gibson BW.

Mol Cell Proteomics. 2015 Sep;14(9):2405-19. doi: 10.1074/mcp.O115.048181. Epub 2015 May 17.

29.

SIRT1 deacetylates RORγt and enhances Th17 cell generation.

Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, Xiao C, Littman DR, Ott M, Verdin E.

J Exp Med. 2015 May 4;212(5):607-17. doi: 10.1084/jem.20132378. Epub 2015 Apr 27. Erratum in: J Exp Med. 2015 Jun 1;212(6):973.

30.

SIRT3 and SIRT5 regulate the enzyme activity and cardiolipin binding of very long-chain acyl-CoA dehydrogenase.

Zhang Y, Bharathi SS, Rardin MJ, Uppala R, Verdin E, Gibson BW, Goetzman ES.

PLoS One. 2015 Mar 26;10(3):e0122297. doi: 10.1371/journal.pone.0122297. eCollection 2015.

31.

Large-Scale Interlaboratory Study to Develop, Analytically Validate and Apply Highly Multiplexed, Quantitative Peptide Assays to Measure Cancer-Relevant Proteins in Plasma.

Abbatiello SE, Schilling B, Mani DR, Zimmerman LJ, Hall SC, MacLean B, Albertolle M, Allen S, Burgess M, Cusack MP, Gosh M, Hedrick V, Held JM, Inerowicz HD, Jackson A, Keshishian H, Kinsinger CR, Lyssand J, Makowski L, Mesri M, Rodriguez H, Rudnick P, Sadowski P, Sedransk N, Shaddox K, Skates SJ, Kuhn E, Smith D, Whiteaker JR, Whitwell C, Zhang S, Borchers CH, Fisher SJ, Gibson BW, Liebler DC, MacCoss MJ, Neubert TA, Paulovich AG, Regnier FE, Tempst P, Carr SA.

Mol Cell Proteomics. 2015 Sep;14(9):2357-74. doi: 10.1074/mcp.M114.047050. Epub 2015 Feb 18.

32.

Iron promotes protein insolubility and aging in C. elegans.

Klang IM, Schilling B, Sorensen DJ, Sahu AK, Kapahi P, Andersen JK, Swoboda P, Killilea DW, Gibson BW, Lithgow GJ.

Aging (Albany NY). 2014 Nov;6(11):975-91.

33.

Comparative analyses of proteins from Haemophilus influenzae biofilm and planktonic populations using metabolic labeling and mass spectrometry.

Post DM, Held JM, Ketterer MR, Phillips NJ, Sahu A, Apicella MA, Gibson BW.

BMC Microbiol. 2014 Dec 31;14:329. doi: 10.1186/s12866-014-0329-9.

34.

Surgeon-rated visualization in shoulder arthroscopy: a randomized blinded controlled trial comparing irrigation fluid with and without epinephrine.

Avery DM 3rd, Gibson BW, Carolan GF.

Arthroscopy. 2015 Jan;31(1):12-8. doi: 10.1016/j.arthro.2014.08.010. Epub 2014 Nov 6.

PMID:
25442659
35.

The E. coli sirtuin CobB shows no preference for enzymatic and nonenzymatic lysine acetylation substrate sites.

AbouElfetouh A, Kuhn ML, Hu LI, Scholle MD, Sorensen DJ, Sahu AK, Becher D, Antelmann H, Mrksich M, Anderson WF, Gibson BW, Schilling B, Wolfe AJ.

Microbiologyopen. 2015 Feb;4(1):66-83. doi: 10.1002/mbo3.223. Epub 2014 Nov 22.

36.

Wavelet-based peak detection and a new charge inference procedure for MS/MS implemented in ProteoWizard's msConvert.

French WR, Zimmerman LJ, Schilling B, Gibson BW, Miller CA, Townsend RR, Sherrod SD, Goodwin CR, McLean JA, Tabb DL.

J Proteome Res. 2015 Feb 6;14(2):1299-307. doi: 10.1021/pr500886y. Epub 2014 Dec 2.

37.

Panorama: a targeted proteomics knowledge base.

Sharma V, Eckels J, Taylor GK, Shulman NJ, Stergachis AB, Joyner SA, Yan P, Whiteaker JR, Halusa GN, Schilling B, Gibson BW, Colangelo CM, Paulovich AG, Carr SA, Jaffe JD, MacCoss MJ, MacLean B.

J Proteome Res. 2014 Sep 5;13(9):4205-10. doi: 10.1021/pr5006636. Epub 2014 Aug 18.

38.

RPL24: a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cancer cell growth.

Wilson-Edell KA, Kehasse A, Scott GK, Yau C, Rothschild DE, Schilling B, Gabriel BS, Yevtushenko MA, Hanson IM, Held JM, Gibson BW, Benz CC.

Oncotarget. 2014 Jul 15;5(13):5165-76.

39.

Variation and quantification among a target set of phosphopeptides in human plasma by multiple reaction monitoring and SWATH-MS2 data-independent acquisition.

Zawadzka AM, Schilling B, Held JM, Sahu AK, Cusack MP, Drake PM, Fisher SJ, Gibson BW.

Electrophoresis. 2014 Dec;35(24):3487-97. doi: 10.1002/elps.201400167. Epub 2014 Jul 10.

40.

A framework for installable external tools in Skyline.

Broudy D, Killeen T, Choi M, Shulman N, Mani DR, Abbatiello SE, Mani D, Ahmad R, Sahu AK, Schilling B, Tamura K, Boss Y, Sharma V, Gibson BW, Carr SA, Vitek O, MacCoss MJ, MacLean B.

Bioinformatics. 2014 Sep 1;30(17):2521-3. doi: 10.1093/bioinformatics/btu148. Epub 2014 May 9.

41.

Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation.

Kuhn ML, Zemaitaitis B, Hu LI, Sahu A, Sorensen D, Minasov G, Lima BP, Scholle M, Mrksich M, Anderson WF, Gibson BW, Schilling B, Wolfe AJ.

PLoS One. 2014 Apr 22;9(4):e94816. doi: 10.1371/journal.pone.0094816. eCollection 2014.

42.

Phosphoprotein secretome of tumor cells as a source of candidates for breast cancer biomarkers in plasma.

Zawadzka AM, Schilling B, Cusack MP, Sahu AK, Drake P, Fisher SJ, Benz CC, Gibson BW.

Mol Cell Proteomics. 2014 Apr;13(4):1034-49. doi: 10.1074/mcp.M113.035485. Epub 2014 Feb 6.

43.

Francisella tularensis Schu S4 lipopolysaccharide core sugar and O-antigen mutants are attenuated in a mouse model of tularemia.

Rasmussen JA, Post DM, Gibson BW, Lindemann SR, Apicella MA, Meyerholz DK, Jones BD.

Infect Immun. 2014 Apr;82(4):1523-39. doi: 10.1128/IAI.01640-13. Epub 2014 Jan 22.

44.

SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks.

Rardin MJ, He W, Nishida Y, Newman JC, Carrico C, Danielson SR, Guo A, Gut P, Sahu AK, Li B, Uppala R, Fitch M, Riiff T, Zhu L, Zhou J, Mulhern D, Stevens RD, Ilkayeva OR, Newgard CB, Jacobson MP, Hellerstein M, Goetzman ES, Gibson BW, Verdin E.

Cell Metab. 2013 Dec 3;18(6):920-33. doi: 10.1016/j.cmet.2013.11.013.

45.

Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site.

Bharathi SS, Zhang Y, Mohsen AW, Uppala R, Balasubramani M, Schreiber E, Uechi G, Beck ME, Rardin MJ, Vockley J, Verdin E, Gibson BW, Hirschey MD, Goetzman ES.

J Biol Chem. 2013 Nov 22;288(47):33837-47. doi: 10.1074/jbc.M113.510354. Epub 2013 Oct 11.

46.

Targeted quantitation of acetylated lysine peptides by selected reaction monitoring mass spectrometry.

Rardin MJ, Held JM, Gibson BW.

Methods Mol Biol. 2013;1077:121-31. doi: 10.1007/978-1-62703-637-5_8.

47.

Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation.

Jing E, O'Neill BT, Rardin MJ, Kleinridders A, Ilkeyeva OR, Ussar S, Bain JR, Lee KY, Verdin EM, Newgard CB, Gibson BW, Kahn CR.

Diabetes. 2013 Oct;62(10):3404-17. doi: 10.2337/db12-1650. Epub 2013 Jul 8.

48.

Site-specific acylation changes in the lipid A of Escherichia coli lpxL mutants grown at high temperatures.

Schilling B, Hunt J, Gibson BW, Apicella MA.

Innate Immun. 2014 Apr;20(3):269-82. doi: 10.1177/1753425913490534. Epub 2013 Jun 28.

49.

Label-Free Quantitation and Mapping of the ErbB2 Tumor Receptor by Multiple Protease Digestion with Data-Dependent (MS1) and Data-Independent (MS2) Acquisitions.

Held JM, Schilling B, D'Souza AK, Srinivasan T, Behring JB, Sorensen DJ, Benz CC, Gibson BW.

Int J Proteomics. 2013;2013:791985. doi: 10.1155/2013/791985. Epub 2013 Apr 4.

50.

Design, implementation and multisite evaluation of a system suitability protocol for the quantitative assessment of instrument performance in liquid chromatography-multiple reaction monitoring-MS (LC-MRM-MS).

Abbatiello SE, Mani DR, Schilling B, Maclean B, Zimmerman LJ, Feng X, Cusack MP, Sedransk N, Hall SC, Addona T, Allen S, Dodder NG, Ghosh M, Held JM, Hedrick V, Inerowicz HD, Jackson A, Keshishian H, Kim JW, Lyssand JS, Riley CP, Rudnick P, Sadowski P, Shaddox K, Smith D, Tomazela D, Wahlander A, Waldemarson S, Whitwell CA, You J, Zhang S, Kinsinger CR, Mesri M, Rodriguez H, Borchers CH, Buck C, Fisher SJ, Gibson BW, Liebler D, Maccoss M, Neubert TA, Paulovich A, Regnier F, Skates SJ, Tempst P, Wang M, Carr SA.

Mol Cell Proteomics. 2013 Sep;12(9):2623-39. doi: 10.1074/mcp.M112.027078. Epub 2013 May 20.

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