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Circulating Tumor DNA Analyses as Markers of Recurrence Risk and Benefit of Adjuvant Therapy for Stage III Colon Cancer.

Tie J, Cohen JD, Wang Y, Christie M, Simons K, Lee M, Wong R, Kosmider S, Ananda S, McKendrick J, Lee B, Cho JH, Faragher I, Jones IT, Ptak J, Schaeffer MJ, Silliman N, Dobbyn L, Li L, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, Gibbs P.

JAMA Oncol. 2019 Oct 17. doi: 10.1001/jamaoncol.2019.3616. [Epub ahead of print]


A Bayesian Assessment of the Longevity of Jeanne Calment.

Zak N, Gibbs P.

Rejuvenation Res. 2019 Oct 3. doi: 10.1089/rej.2019.2227. [Epub ahead of print]


Overexpression of TP53 protein is associated with the lack of adjuvant chemotherapy benefit in patients with stage III colorectal cancer.

Williams DS, Mouradov D, Browne C, Palmieri M, Elliott MJ, Nightingale R, Fang CG, Li R, Mariadason JM, Faragher I, Jones IT, Churilov L, Tebbutt NC, Gibbs P, Sieber OM.

Mod Pathol. 2019 Aug 30. doi: 10.1038/s41379-019-0353-2. [Epub ahead of print]


Differentiation between subcentimeter carcinomas and benign lesions using kinetic parameters derived from ultrafast dynamic contrast-enhanced breast MRI.

Onishi N, Sadinski M, Gibbs P, Gallagher KM, Hughes MC, Ko ES, Dashevsky BZ, Shanbhag DD, Fung MM, Hunt TM, Martinez DF, Shukla-Dave A, Morris EA, Sutton EJ.

Eur Radiol. 2019 Aug 29. doi: 10.1007/s00330-019-06392-5. [Epub ahead of print]


Secondary technical resectability of colorectal cancer liver metastases after chemotherapy with or without selective internal radiotherapy in the randomized SIRFLOX trial.

Garlipp B, Gibbs P, Van Hazel GA, Jeyarajah R, Martin RCG, Bruns CJ, Lang H, Manas DM, Ettorre GM, Pardo F, Donckier V, Benckert C, van Gulik TM, Goéré D, Schoen M, Pratschke J, Bechstein WO, de la Cuesta AM, Adeyemi S, Ricke J, Seidensticker M.

Br J Surg. 2019 Aug 19. doi: 10.1002/bjs.11283. [Epub ahead of print]


Emerging strategies in the initial management of locally advanced rectal cancer.

Gately L, Wong HL, Tie J, Wong R, Lee M, Lee B, Jalali A, Gibbs P.

Future Oncol. 2019 Sep;15(25):2955-2965. doi: 10.2217/fon-2018-0941. Epub 2019 Aug 19.


Pulsatile tinnitus as a presenting symptom of central venous stenosis secondary to an ipsilateral upper arm arteriovenous PTFE graft.

Steele L, Flowers D, Coles S, Gibbs P.

BMJ Case Rep. 2019 Jul 26;12(7). pii: e229398. doi: 10.1136/bcr-2019-229398.


Surveillance arterioveNous fistulAs using ultRasound (SONAR) trial in haemodialysis patients: a study protocol for a multicentre observational study.

Richards J, Hossain M, Summers D, Slater M, Bartlett M, Kosmoliaptsis V, Wilson EC, Lagaac R, Sidders A, Foley C, Laing E, Hopkins V, Fitzpatrick-Creamer C, Hudson C, Thomas H, Turner S, Tambyraja A, Somalanka S, Hunter J, Dutta S, Lawman S, Salter T, Aslam M, Bagul A, Sivaprakasam R, Smith G, Moinuddin Z, Knight S, Gibbs P, Motallebzadeh R, Barnett N, Pettigrew G; SONAR trial group.

BMJ Open. 2019 Jul 23;9(7):e031210. doi: 10.1136/bmjopen-2019-031210.


Clinical Applications of Circulating Tumour DNA in Pancreatic Adenocarcinoma.

Loft M, Lee B, Tie J, Gibbs P.

J Pers Med. 2019 Jul 18;9(3). pii: E37. doi: 10.3390/jpm9030037. Review.


Radiomic features of glucose metabolism enable prediction of outcome in mantle cell lymphoma.

Mayerhoefer ME, Riedl CC, Kumar A, Gibbs P, Weber M, Tal I, Schilksy J, Schöder H.

Eur J Nucl Med Mol Imaging. 2019 Jul 8. doi: 10.1007/s00259-019-04420-6. [Epub ahead of print]


Circulating tumor DNA as a potential marker of adjuvant chemotherapy benefit following surgery for localized pancreatic cancer.

Lee B, Lipton L, Cohen J, Tie J, Javed AA, Li L, Goldstein D, Burge M, Cooray P, Nagrial A, Tebbutt NC, Thomson B, Nikfarjam M, Harris M, Haydon A, Lawrence B, Tai DWM, Simons K, Lennon AM, Wolfgang CL, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, Gibbs P.

Ann Oncol. 2019 Sep 1;30(9):1472-1478. doi: 10.1093/annonc/mdz200.


Human anxiety-specific "theta" occurs with selective stopping and localizes to right inferior frontal gyrus.

Shadli SM, High O, Byers B, Gibbs P, Steller R, Glue P, McNaughton N.

Behav Neurosci. 2019 Jun 20. doi: 10.1037/bne0000316. [Epub ahead of print]


Phase II APEC trial: The impact of primary tumor side on outcomes of first-line cetuximab plus FOLFOX or FOLFIRI in patients with RAS wild-type metastatic colorectal cancer.

Price T, Shen L, Ma B, Esser R, Chen W, Gibbs P, Lim R, Cheng AL.

Asia Pac J Clin Oncol. 2019 Aug;15(4):225-230. doi: 10.1111/ajco.13154. Epub 2019 May 15.


Prognostic Potential of Circulating Tumor DNA Measurement in Postoperative Surveillance of Nonmetastatic Colorectal Cancer.

Wang Y, Li L, Cohen JD, Kinde I, Ptak J, Popoli M, Schaefer J, Silliman N, Dobbyn L, Tie J, Gibbs P, Tomasetti C, Kinzler KW, Papadopoulos N, Vogelstein B, Olsson L.

JAMA Oncol. 2019 May 9. doi: 10.1001/jamaoncol.2019.0512. [Epub ahead of print]


Inflammation, Biomarkers and Immuno-Oncology Pathways in Pancreatic Cancer.

Lee B, Gibbs P.

J Pers Med. 2019 Apr 26;9(2). pii: E20. doi: 10.3390/jpm9020020.


A Comparison of Limb Salvage Versus Amputation for Nonmetastatic Sarcomas Using Patient-reported Outcomes Measurement Information System Outcomes.

Wilke B, Cooper A, Scarborough M, Gibbs P, Spiguel A.

J Am Acad Orthop Surg. 2019 Apr 15;27(8):e381-e389. doi: 10.5435/JAAOS-D-17-00758.


Characterization of Sub-1 cm Breast Lesions Using Radiomics Analysis.

Gibbs P, Onishi N, Sadinski M, Gallagher KM, Hughes M, Martinez DF, Morris EA, Sutton EJ.

J Magn Reson Imaging. 2019 Nov;50(5):1468-1477. doi: 10.1002/jmri.26732. Epub 2019 Mar 27.


Utilisation of systemic therapy options in routine treatment of metastatic colorectal cancer in Australia.

Delahunty R, Lee M, Wong H, Johns J, McKendrick J, Lee B, Kosmider S, Cooray P, Ananda S, Desai J, Tran B, Tie J, Gibbs P, Wong R.

Intern Med J. 2019 Mar 18. doi: 10.1111/imj.14288. [Epub ahead of print]


Pre-Therapeutic Total Lesion Glycolysis on [18F]FDG-PET Enables Prognostication of 2-Year Progression-Free Survival in MALT Lymphoma Patients Treated with CD20-Antibody-Based Immunotherapy.

Mayerhoefer ME, Staudenherz A, Kiesewetter B, Weber M, Simonitsch-Klupp I, Gibbs P, Dolak W, Lukas J, Raderer M.

Mol Imaging Biol. 2019 Mar 7. doi: 10.1007/s11307-019-01329-2. [Epub ahead of print]


Demonstrating the feasibility of collecting secondary, de-identified data on Australian patients receiving treatment as part of a Medicine Access Program.

Lok SW, De Boer R, Cordwell C, Marx G, Fox P, Hasovits C, Rutovitz J, Harold M, Tran B, Wong HL, Gibbs P.

Intern Med J. 2019 Feb 28. doi: 10.1111/imj.14265. [Epub ahead of print]


Impact of access to novel therapies on the initial management of castrate-resistant prostate cancer: an Australian multicentre study.

Kwan EM, Semira MC, Bergin ART, Muttiah C, Beck S, Anton A, Campbell D, Wong S, Rosenthal M, Gibbs P, Tran B.

Intern Med J. 2019 Feb 18. doi: 10.1111/imj.14262. [Epub ahead of print]


Right versus left sided metastatic colorectal cancer: Teasing out clinicopathologic drivers of disparity in survival.

Mendis S, Beck S, Lee B, Lee M, Wong R, Kosmider S, Shapiro J, Yip D, Steel S, Nott L, Jennens R, Lipton L, Burge M, Field K, Ananda S, Wong HL, Gibbs P.

Asia Pac J Clin Oncol. 2019 Jun;15(3):136-143. doi: 10.1111/ajco.13135. Epub 2019 Feb 13.


Registry-based randomized clinical trials as a method to improve cancer care in Australia.

Foroughi S, Wong HL, Gately L, Lee M, Simons K, Tie J, Burgess AW, Gibbs P.

Asia Pac J Clin Oncol. 2019 Jun;15(3):188-189. doi: 10.1111/ajco.13122. Epub 2019 Feb 12. No abstract available.


Baseline Characteristics of Participants in the ASPREE (Aspirin in Reducing Events in the Elderly) Study.

McNeil JJ, Woods RL, Nelson MR, Murray AM, Reid CM, Kirpach B, Storey E, Shah RC, Wolfe RS, Tonkin AM, Newman AB, Williamson JD, Lockery JE, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Trevaks RE, Orchard SG, Beilin LJ, Donnan GA, Gibbs P, Johnston CI, Grimm RH; ASPREE Investigator Group.

J Gerontol A Biol Sci Med Sci. 2019 Apr 23;74(5):748. doi: 10.1093/gerona/gly278. No abstract available.


The potential role of circulating tumor DNA (ctDNA) in the further investigation of colorectal cancer patients with nonspecific findings on standard investigations.

Wong R, Tie J, Lee M, Cohen J, Wang Y, Li L, Ma S, Christie M, Kosmider S, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, Gibbs P.

Int J Cancer. 2019 Jul 15;145(2):540-547. doi: 10.1002/ijc.32117. Epub 2019 Jan 24.


Evaluation of the transferability of survival calculators for stage II/III colon cancer across healthcare systems.

Jorissen RN, Croxford M, Jones IT, Ward RL, Hawkins NJ, Gibbs P, Sieber OM.

Int J Cancer. 2019 Jul 1;145(1):132-142. doi: 10.1002/ijc.32100. Epub 2019 Jan 20.


Hypertension as a predictor of advanced colorectal cancer outcome and cetuximab treatment response.

Sud S, O'Callaghan C, Jonker C, Karapetis C, Price T, Tebbutt N, Shapiro J, Van Hazel G, Pavlakis N, Gibbs P, Jeffrey M, Siu L, Gill S, Wong R, Jonker D, Tu D, Goodwin R.

Curr Oncol. 2018 Dec;25(6):e516-e526. doi: 10.3747/co.25.4069. Epub 2018 Dec 1.


Evaluation of Emergent Mutations in Circulating Cell-Free DNA and Clinical Outcomes in Patients with Metastatic Colorectal Cancer Treated with Panitumumab in the ASPECCT Study.

Peeters M, Price T, Boedigheimer M, Kim TW, Ruff P, Gibbs P, Thomas A, Demonty G, Hool K, Ang A.

Clin Cancer Res. 2019 Feb 15;25(4):1216-1225. doi: 10.1158/1078-0432.CCR-18-2072. Epub 2018 Nov 28.


Good long-term patency: 10-year follow-up using the mid-thigh adductor loop arteriovenous graft.

McEwan SJ, Maple H, Gibbs PJ.

J Vasc Access. 2019 May;20(3):313-320. doi: 10.1177/1129729818805955. Epub 2018 Oct 22.


Chemotherapy and biologic use in the routine management of metastatic colorectal cancer in Australia: is clinical practice following the evidence?

Semira C, Wong HL, Field K, Lee M, Lee B, Nott L, Shapiro J, Wong R, Tie J, Tran B, Richardson G, Zimet A, Lipton L, Tamjid B, Burge M, Ma B, Johns J, Harold M, Gibbs P.

Intern Med J. 2019 Apr;49(4):446-454. doi: 10.1111/imj.14115.


Effect of Aspirin on Disability-free Survival in the Healthy Elderly.

McNeil JJ, Woods RL, Nelson MR, Reid CM, Kirpach B, Wolfe R, Storey E, Shah RC, Lockery JE, Tonkin AM, Newman AB, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ, Donnan GA, Gibbs P, Johnston CI, Ryan J, Radziszewska B, Grimm R, Murray AM; ASPREE Investigator Group.

N Engl J Med. 2018 Oct 18;379(16):1499-1508. doi: 10.1056/NEJMoa1800722. Epub 2018 Sep 16.


Effect of Aspirin on All-Cause Mortality in the Healthy Elderly.

McNeil JJ, Nelson MR, Woods RL, Lockery JE, Wolfe R, Reid CM, Kirpach B, Shah RC, Ives DG, Storey E, Ryan J, Tonkin AM, Newman AB, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ, Donnan GA, Gibbs P, Johnston CI, Radziszewska B, Grimm R, Murray AM; ASPREE Investigator Group.

N Engl J Med. 2018 Oct 18;379(16):1519-1528. doi: 10.1056/NEJMoa1803955. Epub 2018 Sep 16.


Bridging health access disparities among culturally and linguistically diverse cancer patients: an ongoing challenge.

Semira C, Wong HL, Gibbs P.

Intern Med J. 2018 Sep;48(9):1165. doi: 10.1111/imj.14023. No abstract available.


Accuracy of administrative coding data in colorectal cancer resections and short-term outcomes.

MacCallum C, Da Silva N, Gibbs P, Thomson BNJ, Skandarajah A, Hayes I.

ANZ J Surg. 2018 Sep;88(9):876-881. doi: 10.1111/ans.14714. Epub 2018 Aug 3.


Re. "Why Should Vascular Surgeons be More Involved in Kidney Transplantation?"

Inston N, Gibbs P, Gilbert J.

Eur J Vasc Endovasc Surg. 2018 Sep;56(3):456. doi: 10.1016/j.ejvs.2018.06.068. Epub 2018 Jul 27. No abstract available.


Seeding of hepatocellular carcinoma into the stomach wall following endoscopic ultrasound and fine-needle aspiration biopsy.

Kasi M, Rashid S, Wallace SAJ, Sujendran V, Griffiths B, Butler A, Gibbs P, Sreedharan L, Zaitoun AM, Venkatachalapathy S, James MW, Aithal GP.

Oxf Med Case Reports. 2018 Jul 18;2018(7):omy039. doi: 10.1093/omcr/omy039. eCollection 2018 Jul.


Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series.

Domingo E, Camps C, Kaisaki PJ, Parsons MJ, Mouradov D, Pentony MM, Makino S, Palmieri M, Ward RL, Hawkins NJ, Gibbs P, Askautrud H, Oukrif D, Wang H, Wood J, Tomlinson E, Bark Y, Kaur K, Johnstone EC, Palles C, Church DN, Novelli M, Danielsen HE, Sherlock J, Kerr D, Kerr R, Sieber O, Taylor JC, Tomlinson I.

Lancet Gastroenterol Hepatol. 2018 Sep;3(9):635-643. doi: 10.1016/S2468-1253(18)30117-1. Epub 2018 Jul 2.


The survival outcome of patients with metastatic colorectal cancer based on the site of metastases and the impact of molecular markers and site of primary cancer on metastatic pattern.

Prasanna T, Karapetis CS, Roder D, Tie J, Padbury R, Price T, Wong R, Shapiro J, Nott L, Lee M, Chua YJ, Craft P, Piantadosi C, Sorich M, Gibbs P, Yip D.

Acta Oncol. 2018 Nov;57(11):1438-1444. doi: 10.1080/0284186X.2018.1487581. Epub 2018 Jul 23.


Effect of Primary Tumor Side on Survival Outcomes in Untreated Patients With Metastatic Colorectal Cancer When Selective Internal Radiation Therapy Is Added to Chemotherapy: Combined Analysis of Two Randomized Controlled Studies.

Gibbs P, Heinemann V, Sharma NK, Taieb J, Ricke J, Peeters M, Findlay M, Robinson B, Jackson C, Strickland A, Gebski V, Van Buskirk M, Zhao H, van Hazel G; SIRFLOX and FOXFIRE Global Trial Investigators.

Clin Colorectal Cancer. 2018 Dec;17(4):e617-e629. doi: 10.1016/j.clcc.2018.06.001. Epub 2018 Jun 12.


Targeted therapy for metastatic colorectal cancer.

Price TJ, Tang M, Gibbs P, Haller DG, Peeters M, Arnold D, Segelov E, Roy A, Tebbutt N, Pavlakis N, Karapetis C, Burge M, Shapiro J.

Expert Rev Anticancer Ther. 2018 Oct;18(10):991-1006. doi: 10.1080/14737140.2018.1502664. Epub 2018 Aug 3. Review.


Mismatch repair deficiency assessment by immunohistochemistry: for Lynch syndrome screening and beyond.

Wong HL, Christie M, Gately L, Tie J, Lee B, Semira C, Lok SW, Wong R, Gibbs P.

Future Oncol. 2018 Nov;14(26):2725-2739. doi: 10.2217/fon-2018-0319. Epub 2018 Jul 13. Review.


Methods for the evaluation of biomarkers in patients with kidney and liver diseases: multicentre research programme including ELUCIDATE RCT.

Selby PJ, Banks RE, Gregory W, Hewison J, Rosenberg W, Altman DG, Deeks JJ, McCabe C, Parkes J, Sturgeon C, Thompson D, Twiddy M, Bestall J, Bedlington J, Hale T, Dinnes J, Jones M, Lewington A, Messenger MP, Napp V, Sitch A, Tanwar S, Vasudev NS, Baxter P, Bell S, Cairns DA, Calder N, Corrigan N, Del Galdo F, Heudtlass P, Hornigold N, Hulme C, Hutchinson M, Lippiatt C, Livingstone T, Longo R, Potton M, Roberts S, Sim S, Trainor S, Welberry Smith M, Neuberger J, Thorburn D, Richardson P, Christie J, Sheerin N, McKane W, Gibbs P, Edwards A, Soomro N, Adeyoju A, Stewart GD, Hrouda D.

Southampton (UK): NIHR Journals Library; 2018 Jun.


Stage-based Variation in the Effect of Primary Tumor Side on All Stages of Colorectal Cancer Recurrence and Survival.

Lee MM, MacKinlay A, Semira C, Schieber C, Jimeno Yepes AJ, Lee B, Wong R, Hettiarachchige CKH, Gunn N, Tie J, Wong HL, Skinner I, Jones IT, Keck J, Kosmider S, Tran B, Field K, Gibbs P.

Clin Colorectal Cancer. 2018 Sep;17(3):e569-e577. doi: 10.1016/j.clcc.2018.05.008. Epub 2018 May 26.


Previous Bevacizumab and Efficacy of Later Anti-Epidermal Growth Factor Receptor Antibodies in Metastatic Colorectal Cancer: Results From a Large International Registry.

Burge M, Semira C, Lee B, Lee M, Kosmider S, Wong R, Shapiro J, Ma B, Dean AP, Zimet AS, Steel SA, Lok SW, Torres J, Eastgate M, Wong HL, Gibbs P.

Clin Colorectal Cancer. 2018 Sep;17(3):e593-e599. doi: 10.1016/j.clcc.2018.05.009. Epub 2018 Jun 1.


Re-inventing the randomized controlled trial in medical oncology: The registry-based trial.

Foroughi S, Wong HL, Gately L, Lee M, Simons K, Tie J, Burgess AW, Gibbs P.

Asia Pac J Clin Oncol. 2018 Dec;14(6):365-373. doi: 10.1111/ajco.12992. Epub 2018 Jun 26. Review.


The Value of Clinical Colorectal Cancer Registries in Colorectal Cancer Research: A Systematic Review.

MacCallum C, Skandarajah A, Gibbs P, Hayes I.

JAMA Surg. 2018 Sep 1;153(9):841-849. doi: 10.1001/jamasurg.2018.1635.


Impact of Emergent Circulating Tumor DNA RAS Mutation in Panitumumab-Treated Chemoresistant Metastatic Colorectal Cancer.

Kim TW, Peeters M, Thomas A, Gibbs P, Hool K, Zhang J, Ang AL, Bach BA, Price T.

Clin Cancer Res. 2018 Nov 15;24(22):5602-5609. doi: 10.1158/1078-0432.CCR-17-3377. Epub 2018 Jun 13.


MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors.

Sakthianandeswaren A, Parsons MJ, Mouradov D, MacKinnon RN, Catimel B, Liu S, Palmieri M, Love C, Jorissen RN, Li S, Whitehead L, Putoczki TL, Preaudet A, Tsui C, Nowell CJ, Ward RL, Hawkins NJ, Desai J, Gibbs P, Ernst M, Street I, Buchert M, Sieber OM.

Cancer Discov. 2018 Aug;8(8):988-1005. doi: 10.1158/2159-8290.CD-17-0909. Epub 2018 Jun 7.


Treatment of Sarcoma Lung Metastases with Stereotactic Body Radiotherapy.

Lindsay AD, Haupt EE, Chan CM, Spiguel AR, Scarborough MT, Zlotecki RA, Gibbs PC.

Sarcoma. 2018 Apr 1;2018:9132359. doi: 10.1155/2018/9132359. eCollection 2018.


Adjuvant therapy for resected colon cancer 2017, including the IDEA analysis.

Tang M, Price TJ, Shapiro J, Gibbs P, Haller DG, Arnold D, Peeters M, Segelov E, Roy A, Tebbutt N, Pavlakis N, Karapetis C, Burge M.

Expert Rev Anticancer Ther. 2018 Apr;18(4):339-349. doi: 10.1080/14737140.2018.1444481. Epub 2018 Mar 1. Review.


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