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Items: 1 to 50 of 429

1.

The Good, the Bad and the Unknown of CD38 in the Metabolic Microenvironment and Immune Cell Functionality of Solid Tumors.

Konen JM, Fradette JJ, Gibbons DL.

Cells. 2019 Dec 24;9(1). pii: E52. doi: 10.3390/cells9010052. Review.

2.

A Horizon Scan of Emerging Global Biological Conservation Issues for 2020.

Sutherland WJ, Dias MP, Dicks LV, Doran H, Entwistle AC, Fleishman E, Gibbons DW, Hails R, Hughes AC, Hughes J, Kelman R, Le Roux X, LeAnstey B, Lickorish FA, Maggs L, Pearce-Higgins JW, Peck LS, Pettorelli N, Pretty J, Spalding MD, Tonneijck FH, Wentworth J, Thornton A.

Trends Ecol Evol. 2020 Jan;35(1):81-90. doi: 10.1016/j.tree.2019.10.010. Epub 2019 Dec 5. Review.

PMID:
31813647
3.

Phase II Trial of Concurrent Atezolizumab With Chemoradiation for Unresectable NSCLC.

Lin SH, Lin Y, Yao L, Kalhor N, Carter BW, Altan M, Blumenschein G, Byers LA, Fossella F, Gibbons DL, Kurie JM, Lu C, Simon G, Skoulidis F, Chang JY, Jeter MD, Liao Z, Gomez DR, O'Reilly M, Papadimitrakopoulou V, Thall P, Heymach JV, Tsao AS.

J Thorac Oncol. 2019 Nov 25. pii: S1556-0864(19)33659-7. doi: 10.1016/j.jtho.2019.10.024. [Epub ahead of print]

PMID:
31778797
4.

ZEB1/NuRD complex suppresses TBC1D2b to stimulate E-cadherin internalization and promote metastasis in lung cancer.

Manshouri R, Coyaud E, Kundu ST, Peng DH, Stratton SA, Alton K, Bajaj R, Fradette JJ, Minelli R, Peoples MD, Carugo A, Chen F, Bristow C, Kovacs JJ, Barton MC, Heffernan T, Creighton CJ, Raught B, Gibbons DL.

Nat Commun. 2019 Nov 12;10(1):5125. doi: 10.1038/s41467-019-12832-z.

5.

Mechanobiological modulation of in situ and in vivo osteocyte calcium oscillation by acoustic radiation force.

Hu M, Lee W, Jiao J, Li X, Gibbons DE, Hassan CR, Tian GW, Qin YX.

Ann N Y Acad Sci. 2019 Oct 23. doi: 10.1111/nyas.14262. [Epub ahead of print]

PMID:
31646646
6.

Is the Adoption of ERAS Protocols into Spinal Surgery Inevitable?

McDonnell J, Conti A, Gibbons D, Ahern DP, Butler JS.

Clin Spine Surg. 2019 Oct 1. doi: 10.1097/BSD.0000000000000900. [Epub ahead of print] No abstract available.

PMID:
31577613
7.

Lymphovascular Invasion Is Associated with Mutational Burden and PD-L1 in Resected Lung Cancer.

Mitchell KG, Negrao MV, Parra ER, Li J, Zhang J, Dejima H, Vaporciyan AA, Swisher SG, Weissferdt A, Antonoff MB, Cascone T, Roarty E, Wistuba II, Heymach JV, Gibbons DL, Zhang J, Sepesi B.

Ann Thorac Surg. 2019 Sep 21. pii: S0003-4975(19)31416-X. doi: 10.1016/j.athoracsur.2019.08.029. [Epub ahead of print]

PMID:
31550464
8.

Thoracic spinal cord neuromodulation obtunds dorsal root ganglion afferent neuronal transduction of the ischemic ventricle.

Salavatian S, Ardell SM, Hammer M, Gibbons D, Armour JA, Ardell JL.

Am J Physiol Heart Circ Physiol. 2019 Nov 1;317(5):H1134-H1141. doi: 10.1152/ajpheart.00257.2019. Epub 2019 Sep 20.

PMID:
31538809
9.

Management of Herniated Lumbar Disk Disease and Cauda Equina Syndrome in Pregnancy.

Ahern DP, Gibbons D, Johnson GP, Murphy TM, Schroeder GD, Vaccaro AR, Butler JS.

Clin Spine Surg. 2019 Dec;32(10):412-416. doi: 10.1097/BSD.0000000000000886.

PMID:
31498273
10.

Image-guidance, Robotics, and the Future of Spine Surgery.

Ahern DP, Gibbons D, Schroeder GD, Vaccaro AR, Butler JS.

Clin Spine Surg. 2019 Aug 14. doi: 10.1097/BSD.0000000000000809. [Epub ahead of print]

PMID:
31425306
11.

Conformational Re-engineering of Porphyrins as Receptors with Switchable N-H⋅⋅⋅X-Type Binding Modes.

Norvaiša K, Flanagan KJ, Gibbons D, Senge MO.

Angew Chem Int Ed Engl. 2019 Nov 11;58(46):16553-16557. doi: 10.1002/anie.201907929. Epub 2019 Sep 24.

12.

Suppressed immune microenvironment and repertoire in brain metastases from patients with resected non-small-cell lung cancer.

Kudo Y, Haymaker C, Zhang J, Reuben A, Duose DY, Fujimoto J, Roy-Chowdhuri S, Solis Soto LM, Dejima H, Parra ER, Mino B, Abraham R, Ikeda N, Vaporcyan A, Gibbons D, Zhang J, Lang FF, Luthra R, Lee JJ, Moran C, Huse JT, Kadara H, Wistuba II.

Ann Oncol. 2019 Sep 1;30(9):1521-1530. doi: 10.1093/annonc/mdz207.

PMID:
31282941
13.

A systematic review of the presentation of scan-negative suspected cauda equina syndrome.

McDonnell J, Ahern DP, Gibbons D, Dalton DM, Butler JS.

Surgeon. 2019 Jun 11. pii: S1479-666X(19)30062-9. doi: 10.1016/j.surge.2019.04.003. [Epub ahead of print] Review.

PMID:
31201127
14.

Female family members lack understanding of indeterminate negative BRCA1/2 test results shared by probands.

Himes DO, Gibbons DK, Birmingham WC, Beckstrand RL, Gammon A, Kinney AY, Clayton MF.

J Genet Couns. 2019 Oct;28(5):950-961. doi: 10.1002/jgc4.1147. Epub 2019 Jun 14.

PMID:
31199558
15.

Targeting the Interplay between Epithelial-to-Mesenchymal-Transition and the Immune System for Effective Immunotherapy.

Soundararajan R, Fradette JJ, Konen JM, Moulder S, Zhang X, Gibbons DL, Varadarajan N, Wistuba II, Tripathy D, Bernatchez C, Byers LA, Chang JT, Contreras A, Lim B, Parra ER, Roarty EB, Wang J, Yang F, Barton M, Rosen JM, Mani SA.

Cancers (Basel). 2019 May 24;11(5). pii: E714. doi: 10.3390/cancers11050714. Review.

16.

Local Consolidative Therapy Vs. Maintenance Therapy or Observation for Patients With Oligometastatic Non-Small-Cell Lung Cancer: Long-Term Results of a Multi-Institutional, Phase II, Randomized Study.

Gomez DR, Tang C, Zhang J, Blumenschein GR Jr, Hernandez M, Lee JJ, Ye R, Palma DA, Louie AV, Camidge DR, Doebele RC, Skoulidis F, Gaspar LE, Welsh JW, Gibbons DL, Karam JA, Kavanagh BD, Tsao AS, Sepesi B, Swisher SG, Heymach JV.

J Clin Oncol. 2019 Jun 20;37(18):1558-1565. doi: 10.1200/JCO.19.00201. Epub 2019 May 8.

PMID:
31067138
17.

Functionalization of Deutero- and Protoporphyrin IX Dimethyl Esters via Palladium-Catalyzed Coupling Reactions.

O'Brien JM, Sitte E, Flanagan KJ, Kühner H, Hallen LJ, Gibbons D, Senge MO.

J Org Chem. 2019 May 17;84(10):6158-6173. doi: 10.1021/acs.joc.9b00350. Epub 2019 Apr 26.

PMID:
30990039
18.

Ntrk1 Promotes Resistance to PD-1 Checkpoint Blockade in Mesenchymal Kras/p53 Mutant Lung Cancer.

Konen JM, Rodriguez BL, Fradette JJ, Gibson L, Davis D, Minelli R, Peoples MD, Kovacs J, Carugo A, Bristow C, Heffernan T, Gibbons DL.

Cancers (Basel). 2019 Apr 2;11(4). pii: E462. doi: 10.3390/cancers11040462.

19.

Structure and conformation of photosynthetic pigments and related compounds. 15. Conformational analysis of chlorophyll derivatives - implications for hydroporphyrins in vivo.

Gibbons D, Flanagan KJ, Pounot L, Senge MO.

Photochem Photobiol Sci. 2019 Jun 12;18(6):1479-1494. doi: 10.1039/c8pp00500a.

PMID:
30964476
20.

Is the Use of a Cervical Collar Necessary in the Nonoperative Management of Type II Peg Fractures in the Elderly?

Leddy L, Temperley H, Gibbons D, Ahern DP, Butler JS.

Clin Spine Surg. 2019 Mar 28. doi: 10.1097/BSD.0000000000000821. [Epub ahead of print] No abstract available.

PMID:
30925496
21.

A novel ex vivo tumor system identifies Src-mediated invasion and metastasis in mesenchymal tumor cells in non-small cell lung cancer.

Padhye A, Ungewiss C, Fradette JJ, Rodriguez BL, Albritton JL, Miller JS, Gibbons DL.

Sci Rep. 2019 Mar 20;9(1):4819. doi: 10.1038/s41598-019-41301-2.

22.

Fine-Needle Aspiration Biopsy Management of the Axilla in Primary Breast Carcinoma.

Gibbons CE, Quinn CM, Gibbons D.

Acta Cytol. 2019;63(4):314-318. doi: 10.1159/000496159. Epub 2019 Mar 20.

PMID:
30893685
23.

ZEB1 suppression sensitizes KRAS mutant cancers to MEK inhibition by an IL17RD-dependent mechanism.

Peng DH, Kundu ST, Fradette JJ, Diao L, Tong P, Byers LA, Wang J, Canales JR, Villalobos PA, Mino B, Yang Y, Minelli R, Peoples MD, Bristow CA, Heffernan TP, Carugo A, Wistuba II, Gibbons DL.

Sci Transl Med. 2019 Mar 13;11(483). pii: eaaq1238. doi: 10.1126/scitranslmed.aaq1238.

24.

PD-L1 Expression, Tumor Mutational Burden, and Cancer Gene Mutations Are Stronger Predictors of Benefit from Immune Checkpoint Blockade than HLA Class I Genotype in Non-Small Cell Lung Cancer.

Negrao MV, Lam VK, Reuben A, Rubin ML, Landry LL, Roarty EB, Rinsurongkawong W, Lewis J, Roth JA, Swisher SG, Gibbons DL, Wistuba II, Papadimitrakopoulou V, Glisson BS, Blumenschein GR Jr, Lee JJ, Heymach JV, Zhang J.

J Thorac Oncol. 2019 Jun;14(6):1021-1031. doi: 10.1016/j.jtho.2019.02.008. Epub 2019 Feb 16.

PMID:
30780001
25.

Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer.

Sen T, Rodriguez BL, Chen L, Corte CMD, Morikawa N, Fujimoto J, Cristea S, Nguyen T, Diao L, Li L, Fan Y, Yang Y, Wang J, Glisson BS, Wistuba II, Sage J, Heymach JV, Gibbons DL, Byers LA.

Cancer Discov. 2019 May;9(5):646-661. doi: 10.1158/2159-8290.CD-18-1020. Epub 2019 Feb 18.

PMID:
30777870
26.

In vitro co-culture and ex vivo organ culture assessment of primed and cryopreserved stromal cell microcapsules for intervertebral disc regeneration.

Naqvi SM, Gansau J, Gibbons D, Buckley CT.

Eur Cell Mater. 2019 Feb 15;37:134-152. doi: 10.22203/eCM.v037a09.

27.

Conservation charities top citation charts.

Butchart SHM, Clements A, Gibbons DW.

Nature. 2019 Feb;566(7743):182. doi: 10.1038/d41586-019-00549-4. No abstract available.

PMID:
30755760
28.

Familial chronic megacolon presenting in childhood or adulthood: Seeking the presumed gene association.

Camilleri M, Wieben E, Eckert D, Carlson P, Hurley O'Dwyer R, Gibbons D, Acosta A, Klee EW.

Neurogastroenterol Motil. 2019 Apr;31(4):e13550. doi: 10.1111/nmo.13550. Epub 2019 Jan 20.

PMID:
30663199
29.

Ten Years On: A Review of the First Global Conservation Horizon Scan.

Sutherland WJ, Fleishman E, Clout M, Gibbons DW, Lickorish F, Peck LS, Pretty J, Spalding M, Ockendon N.

Trends Ecol Evol. 2019 Feb;34(2):139-153. doi: 10.1016/j.tree.2018.12.003. Epub 2019 Jan 2. Review.

PMID:
30611398
30.

Operative Management of Perinatal Lumbar Disc Herniation and Cauda Equina Syndrome: A Case Series

Ahern DP, Gibbons D, Dodds M, Timlin M, Cassidy N, Morris S, Synnott K, Butler JS.

Ir Med J. 2018 Dec 6;111(10):843.

PMID:
30560639
31.

A Horizon Scan of Emerging Issues for Global Conservation in 2019.

Sutherland WJ, Broad S, Butchart SHM, Clarke SJ, Collins AM, Dicks LV, Doran H, Esmail N, Fleishman E, Frost N, Gaston KJ, Gibbons DW, Hughes AC, Jiang Z, Kelman R, LeAnstey B, le Roux X, Lickorish FA, Monk KA, Mortimer D, Pearce-Higgins JW, Peck LS, Pettorelli N, Pretty J, Seymour CL, Spalding MD, Wentworth J, Ockendon N.

Trends Ecol Evol. 2019 Jan;34(1):83-94. doi: 10.1016/j.tree.2018.11.001. Epub 2018 Dec 13. Review.

32.

Effects of CDX2 on prognosis and chemotherapy responsiveness in mismatch repair-deficient colorectal cancer.

Ryan ÉJ, Creavin B, Khaw YL, Kelly ME, Mohan HM, Geraghty R, Ryan EJ, Kennelly R, Hanly A, Martin ST, Fennelly D, McDermott R, Gibbons D, O'Connell PR, Sheahan K, Winter DC.

BJS Open. 2018 Jul 24;2(6):456-463. doi: 10.1002/bjs5.91. eCollection 2018 Dec.

33.

Short-term and long-term effects of caesarean section on the health of women and children.

Sandall J, Tribe RM, Avery L, Mola G, Visser GH, Homer CS, Gibbons D, Kelly NM, Kennedy HP, Kidanto H, Taylor P, Temmerman M.

Lancet. 2018 Oct 13;392(10155):1349-1357. doi: 10.1016/S0140-6736(18)31930-5. Review.

PMID:
30322585
34.

Crystal structure and synthesis of 3-(1H-pyrrol-2-yl)-1-(thio-phen-2-yl)propanone.

Gibbons D, Emandi G, Senge MO.

Acta Crystallogr E Crystallogr Commun. 2018 Sep 21;74(Pt 10):1463-1466. doi: 10.1107/S2056989018012331. eCollection 2018 Oct 1.

35.

The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network.

Tan X, Banerjee P, Liu X, Yu J, Gibbons DL, Wu P, Scott KL, Diao L, Zheng X, Wang J, Jalali A, Suraokar M, Fujimoto J, Behrens C, Liu X, Liu CG, Creighton CJ, Wistuba II, Kurie JM.

J Clin Invest. 2018 Jul 2;128(7):3198. doi: 10.1172/JCI122740. Epub 2018 Jul 2. No abstract available.

36.

TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins.

Kundu ST, Grzeskowiak CL, Fradette JJ, Gibson LA, Rodriguez LB, Creighton CJ, Scott KL, Gibbons DL.

Nat Commun. 2018 Jul 16;9(1):2731. doi: 10.1038/s41467-018-05013-x.

37.

In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer.

Grzeskowiak CL, Kundu ST, Mo X, Ivanov AA, Zagorodna O, Lu H, Chapple RH, Tsang YH, Moreno D, Mosqueda M, Eterovic K, Fradette JJ, Ahmad S, Chen F, Chong Z, Chen K, Creighton CJ, Fu H, Mills GB, Gibbons DL, Scott KL.

Nat Commun. 2018 Jul 16;9(1):2732. doi: 10.1038/s41467-018-04572-3.

38.

CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade.

Chen L, Diao L, Yang Y, Yi X, Rodriguez BL, Li Y, Villalobos PA, Cascone T, Liu X, Tan L, Lorenzi PL, Huang A, Zhao Q, Peng D, Fradette JJ, Peng DH, Ungewiss C, Roybal J, Tong P, Oba J, Skoulidis F, Peng W, Carter BW, Gay CM, Fan Y, Class CA, Zhu J, Rodriguez-Canales J, Kawakami M, Byers LA, Woodman SE, Papadimitrakopoulou VA, Dmitrovsky E, Wang J, Ullrich SE, Wistuba II, Heymach JV, Qin FX, Gibbons DL.

Cancer Discov. 2018 Sep;8(9):1156-1175. doi: 10.1158/2159-8290.CD-17-1033. Epub 2018 Jul 16.

39.

Effect of neoadjuvant chemotherapy on the immune microenvironment in non-small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis approaches.

Parra ER, Villalobos P, Behrens C, Jiang M, Pataer A, Swisher SG, William WN Jr, Zhang J, Lee J, Cascone T, Heymach JV, Forget MA, Haymaker C, Bernatchez C, Kalhor N, Weissferdt A, Moran C, Zhang J, Vaporciyan A, Gibbons DL, Sepesi B, Wistuba II.

J Immunother Cancer. 2018 Jun 6;6(1):48. doi: 10.1186/s40425-018-0368-0.

40.

A review of predation as a limiting factor for bird populations in mesopredator-rich landscapes: a case study of the UK.

Roos S, Smart J, Gibbons DW, Wilson JD.

Biol Rev Camb Philos Soc. 2018 Nov;93(4):1915-1937. doi: 10.1111/brv.12426. Epub 2018 May 22.

PMID:
29790246
41.

Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up.

Kadara H, Choi M, Zhang J, Parra ER, Rodriguez-Canales J, Gaffney SG, Zhao Z, Behrens C, Fujimoto J, Chow C, Yoo Y, Kalhor N, Moran C, Rimm D, Swisher S, Gibbons DL, Heymach J, Kaftan E, Townsend JP, Lynch TJ, Schlessinger J, Lee J, Lifton RP, Wistuba II, Herbst RS.

Ann Oncol. 2018 Apr 1;29(4):1072. doi: 10.1093/annonc/mdx062. No abstract available.

42.

Immunohistochemical and Image Analysis-Based Study Shows That Several Immune Checkpoints are Co-expressed in Non-Small Cell Lung Carcinoma Tumors.

Parra ER, Villalobos P, Zhang J, Behrens C, Mino B, Swisher S, Sepesi B, Weissferdt A, Kalhor N, Heymach JV, Moran C, Zhang J, Lee J, Rodriguez-Canales J, Gibbons D, Wistuba II.

J Thorac Oncol. 2018 Jun;13(6):779-791. doi: 10.1016/j.jtho.2018.03.002. Epub 2018 Mar 8.

43.

Prognostic Value of PD-L1 mRNA Sequencing Expression Profile in Non-Small Cell Lung Cancer.

Sepesi B, Nelson DB, Mitchell KG, Gibbons DL, Heymach JV, Vaporciyan AA, Swisher SG, Roszik J.

Ann Thorac Surg. 2018 Jun;105(6):1621-1626. doi: 10.1016/j.athoracsur.2018.01.081. Epub 2018 Mar 3.

PMID:
29510096
44.

Pan-Cancer Molecular Classes Transcending Tumor Lineage Across 32 Cancer Types, Multiple Data Platforms, and over 10,000 Cases.

Chen F, Zhang Y, Gibbons DL, Deneen B, Kwiatkowski DJ, Ittmann M, Creighton CJ.

Clin Cancer Res. 2018 May 1;24(9):2182-2193. doi: 10.1158/1078-0432.CCR-17-3378. Epub 2018 Feb 9.

45.

The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network.

Tan X, Banerjee P, Liu X, Yu J, Gibbons DL, Wu P, Scott KL, Diao L, Zheng X, Wang J, Jalali A, Suraokar M, Fujimoto J, Behrens C, Liu X, Liu CG, Creighton CJ, Wistuba II, Kurie JM.

J Clin Invest. 2018 Apr 2;128(4):1267-1282. doi: 10.1172/JCI97225. Epub 2018 Feb 26. Erratum in: J Clin Invest. 2018 Jul 2;128(7):3198.

46.

Overcoming resistance to anti-PD immunotherapy in a syngeneic mouse lung cancer model using locoregional virotherapy.

Yan X, Wang L, Zhang R, Pu X, Wu S, Yu L, Meraz IM, Zhang X, Wang JF, Gibbons DL, Mehran RJ, Swisher SG, Roth JA, Fang B.

Oncoimmunology. 2017 Oct 31;7(1):e1376156. doi: 10.1080/2162402X.2017.1376156. eCollection 2017.

47.

The fibrotic tumor stroma.

Yamauchi M, Barker TH, Gibbons DL, Kurie JM.

J Clin Invest. 2018 Jan 2;128(1):16-25. doi: 10.1172/JCI93554. Epub 2018 Jan 2. Review.

48.

A 2018 Horizon Scan of Emerging Issues for Global Conservation and Biological Diversity.

Sutherland WJ, Butchart SHM, Connor B, Culshaw C, Dicks LV, Dinsdale J, Doran H, Entwistle AC, Fleishman E, Gibbons DW, Jiang Z, Keim B, Roux XL, Lickorish FA, Markillie P, Monk KA, Mortimer D, Pearce-Higgins JW, Peck LS, Pretty J, Seymour CL, Spalding MD, Tonneijck FH, Gleave RA.

Trends Ecol Evol. 2018 Jan;33(1):47-58. doi: 10.1016/j.tree.2017.11.006. Epub 2017 Dec 4. Review.

49.

An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Part 2: impacts on organisms and ecosystems.

Pisa L, Goulson D, Yang EC, Gibbons D, Sánchez-Bayo F, Mitchell E, Aebi A, van der Sluijs J, MacQuarrie CJK, Giorio C, Long EY, McField M, Bijleveld van Lexmond M, Bonmatin JM.

Environ Sci Pollut Res Int. 2017 Nov 9. doi: 10.1007/s11356-017-0341-3. [Epub ahead of print]

PMID:
29124633
50.

Tumor Budding and PDC Grade Are Stage Independent Predictors of Clinical Outcome in Mismatch Repair Deficient Colorectal Cancer.

Ryan É, Khaw YL, Creavin B, Geraghty R, Ryan EJ, Gibbons D, Hanly A, Martin ST, O'Connell PR, Winter DC, Sheahan K.

Am J Surg Pathol. 2018 Jan;42(1):60-68. doi: 10.1097/PAS.0000000000000931.

PMID:
29112018

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