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Items: 23


ProteomicsDB: a multi-omics and multi-organism resource for life science research.

Samaras P, Schmidt T, Frejno M, Gessulat S, Reinecke M, Jarzab A, Zecha J, Mergner J, Giansanti P, Ehrlich HC, Aiche S, Rank J, Kienegger H, Krcmar H, Kuster B, Wilhelm M.

Nucleic Acids Res. 2020 Jan 8;48(D1):D1153-D1163. doi: 10.1093/nar/gkz974.


Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation.

Dondelinger Y, Delanghe T, Priem D, Wynosky-Dolfi MA, Sorobetea D, Rojas-Rivera D, Giansanti P, Roelandt R, Gropengiesser J, Ruckdeschel K, Savvides SN, Heck AJR, Vandenabeele P, Brodsky IE, Bertrand MJM.

Nat Commun. 2019 Apr 15;10(1):1729. doi: 10.1038/s41467-019-09690-0.


Effects of Acetylation and Phosphorylation on Subunit Interactions in Three Large Eukaryotic Complexes.

Šoštarić N, O'Reilly FJ, Giansanti P, Heck AJR, Gavin AC, van Noort V.

Mol Cell Proteomics. 2018 Dec;17(12):2387-2401. doi: 10.1074/mcp.RA118.000892. Epub 2018 Sep 4.


Opposite Electron-Transfer Dissociation and Higher-Energy Collisional Dissociation Fragmentation Characteristics of Proteolytic K/R(X)n and (X)nK/R Peptides Provide Benefits for Peptide Sequencing in Proteomics and Phosphoproteomics.

Tsiatsiani L, Giansanti P, Scheltema RA, van den Toorn H, Overall CM, Altelaar AF, Heck AJ.

J Proteome Res. 2017 Feb 3;16(2):852-861. doi: 10.1021/acs.jproteome.6b00825. Epub 2016 Dec 2.


Six alternative proteases for mass spectrometry-based proteomics beyond trypsin.

Giansanti P, Tsiatsiani L, Low TY, Heck AJ.

Nat Protoc. 2016 May;11(5):993-1006. doi: 10.1038/nprot.2016.057. Epub 2016 Apr 28.


NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling.

Dondelinger Y, Jouan-Lanhouet S, Divert T, Theatre E, Bertin J, Gough PJ, Giansanti P, Heck AJ, Dejardin E, Vandenabeele P, Bertrand MJ.

Mol Cell. 2015 Oct 1;60(1):63-76. doi: 10.1016/j.molcel.2015.07.032. Epub 2015 Sep 3.


PhosphoPath: Visualization of Phosphosite-centric Dynamics in Temporal Molecular Networks.

Raaijmakers LM, Giansanti P, Possik PA, Mueller J, Peeper DS, Heck AJ, Altelaar AF.

J Proteome Res. 2015 Oct 2;14(10):4332-41. doi: 10.1021/acs.jproteome.5b00529. Epub 2015 Sep 8.


An Augmented Multiple-Protease-Based Human Phosphopeptide Atlas.

Giansanti P, Aye TT, van den Toorn H, Peng M, van Breukelen B, Heck AJ.

Cell Rep. 2015 Jun 23;11(11):1834-43. doi: 10.1016/j.celrep.2015.05.029. Epub 2015 Jun 11.


Phosphoproteomics-mediated identification of Fer kinase as a target of mutant Shp2 in Noonan and LEOPARD syndrome.

Paardekooper Overman J, Preisinger C, Prummel K, Bonetti M, Giansanti P, Heck A, den Hertog J.

PLoS One. 2014 Sep 3;9(9):e106682. doi: 10.1371/journal.pone.0106682. eCollection 2014.


PZR coordinates Shp2 Noonan and LEOPARD syndrome signaling in zebrafish and mice.

Paardekooper Overman J, Yi JS, Bonetti M, Soulsby M, Preisinger C, Stokes MP, Hui L, Silva JC, Overvoorde J, Giansanti P, Heck AJ, Kontaridis MI, den Hertog J, Bennett AM.

Mol Cell Biol. 2014 Aug;34(15):2874-89. doi: 10.1128/MCB.00135-14. Epub 2014 May 27.


Single-step enrichment by Ti4+-IMAC and label-free quantitation enables in-depth monitoring of phosphorylation dynamics with high reproducibility and temporal resolution.

de Graaf EL, Giansanti P, Altelaar AF, Heck AJ.

Mol Cell Proteomics. 2014 Sep;13(9):2426-34. doi: 10.1074/mcp.O113.036608. Epub 2014 May 21.


Evaluating the promiscuous nature of tyrosine kinase inhibitors assessed in A431 epidermoid carcinoma cells by both chemical- and phosphoproteomics.

Giansanti P, Preisinger C, Huber KV, Gridling M, Superti-Furga G, Bennett KL, Heck AJ.

ACS Chem Biol. 2014 Jul 18;9(7):1490-8. doi: 10.1021/cb500116c. Epub 2014 May 14.


Daily rhythms in the cyanobacterium synechococcus elongatus probed by high-resolution mass spectrometry-based proteomics reveals a small defined set of cyclic proteins.

Guerreiro AC, Benevento M, Lehmann R, van Breukelen B, Post H, Giansanti P, Maarten Altelaar AF, Axmann IM, Heck AJ.

Mol Cell Proteomics. 2014 Aug;13(8):2042-55. doi: 10.1074/mcp.M113.035840. Epub 2014 Mar 27.


Quantitative and qualitative proteome characteristics extracted from in-depth integrated genomics and proteomics analysis.

Low TY, van Heesch S, van den Toorn H, Giansanti P, Cristobal A, Toonen P, Schafer S, Hübner N, van Breukelen B, Mohammed S, Cuppen E, Heck AJ, Guryev V.

Cell Rep. 2013 Dec 12;5(5):1469-78. doi: 10.1016/j.celrep.2013.10.041. Epub 2013 Nov 27.


Interrogating cAMP-dependent kinase signaling in Jurkat T cells via a protein kinase A targeted immune-precipitation phosphoproteomics approach.

Giansanti P, Stokes MP, Silva JC, Scholten A, Heck AJ.

Mol Cell Proteomics. 2013 Nov;12(11):3350-9. doi: 10.1074/mcp.O113.028456. Epub 2013 Jul 23.


In-house construction of a UHPLC system enabling the identification of over 4000 protein groups in a single analysis.

Cristobal A, Hennrich ML, Giansanti P, Goerdayal SS, Heck AJ, Mohammed S.

Analyst. 2012 Aug 7;137(15):3541-8. doi: 10.1039/c2an35445d. Epub 2012 Jun 25.


Flavonoids: chemical properties and analytical methodologies of identification and quantitation in foods and plants.

Corradini E, Foglia P, Giansanti P, Gubbiotti R, Samperi R, Lagana A.

Nat Prod Res. 2011 Mar;25(5):469-95. doi: 10.1080/14786419.2010.482054. Review.


Evaluation of toxicity, genotoxicity and environmental risk of simulated textile and tannery wastewaters with a battery of biotests.

Tigini V, Giansanti P, Mangiavillano A, Pannocchia A, Varese GC.

Ecotoxicol Environ Saf. 2011 May;74(4):866-73. doi: 10.1016/j.ecoenv.2010.12.001. Epub 2010 Dec 21.


Cunninghamella elegans biomass optimisation for textile wastewater biosorption treatment: an analytical and ecotoxicological approach.

Tigini V, Prigione V, Donelli I, Anastasi A, Freddi G, Giansanti P, Mangiavillano A, Varese GC.

Appl Microbiol Biotechnol. 2011 Apr;90(1):343-52. doi: 10.1007/s00253-010-3010-8. Epub 2010 Dec 3.


Existence of hybrid structures in cationic liposome/DNA complexes revealed by their interaction with plasma proteins.

Amenitsch H, Caracciolo G, Foglia P, Fuscoletti V, Giansanti P, Marianecci C, Pozzi D, Laganà A.

Colloids Surf B Biointerfaces. 2011 Jan 1;82(1):141-6. doi: 10.1016/j.colsurfb.2010.08.030. Epub 2010 Aug 26.


Recent developments in matrix solid-phase dispersion extraction.

Capriotti AL, Cavaliere C, Giansanti P, Gubbiotti R, Samperi R, Laganà A.

J Chromatogr A. 2010 Apr 16;1217(16):2521-32. doi: 10.1016/j.chroma.2010.01.030. Epub 2010 Jan 18. Review.


Scale-up of a bioprocess for textile wastewater treatment using Bjerkandera adusta.

Anastasi A, Spina F, Prigione V, Tigini V, Giansanti P, Varese GC.

Bioresour Technol. 2010 May;101(9):3067-75. doi: 10.1016/j.biortech.2009.12.067. Epub 2010 Jan 13.


Liquid chromatography-negative ion atmospheric pressure photoionization tandem mass spectrometry for the determination of brominated flame retardants in environmental water and industrial effluents.

Bacaloni A, Callipo L, Corradini E, Giansanti P, Gubbiotti R, Samperi R, Laganà A.

J Chromatogr A. 2009 Sep 4;1216(36):6400-9. doi: 10.1016/j.chroma.2009.07.039. Epub 2009 Jul 29.


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