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Items: 9


Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers.

Blakely CM, Watkins TBK, Wu W, Gini B, Chabon JJ, McCoach CE, McGranahan N, Wilson GA, Birkbak NJ, Olivas VR, Rotow J, Maynard A, Wang V, Gubens MA, Banks KC, Lanman RB, Caulin AF, St John J, Cordero AR, Giannikopoulos P, Simmons AD, Mack PC, Gandara DR, Husain H, Doebele RC, Riess JW, Diehn M, Swanton C, Bivona TG.

Nat Genet. 2017 Dec;49(12):1693-1704. doi: 10.1038/ng.3990. Epub 2017 Nov 6.


Oncogenic activation of the PI3-kinase p110β isoform via the tumor-derived PIK3Cβ(D1067V) kinase domain mutation.

Pazarentzos E, Giannikopoulos P, Hrustanovic G, St John J, Olivas VR, Gubens MA, Balassanian R, Weissman J, Polkinghorn W, Bivona TG.

Oncogene. 2016 Mar 3;35(9):1198-205. doi: 10.1038/onc.2015.173. Epub 2015 May 18.


Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences.

Pugh TJ, Yu W, Yang J, Field AL, Ambrogio L, Carter SL, Cibulskis K, Giannikopoulos P, Kiezun A, Kim J, McKenna A, Nickerson E, Getz G, Hoffher S, Messinger YH, Dehner LP, Roberts CW, Rodriguez-Galindo C, Williams GM, Rossi CT, Meyerson M, Hill DA.

Oncogene. 2014 Nov 6;33(45):5295-302. doi: 10.1038/onc.2014.150. Epub 2014 Jun 9.


The impact of EGFR T790M mutations and BIM mRNA expression on outcome in patients with EGFR-mutant NSCLC treated with erlotinib or chemotherapy in the randomized phase III EURTAC trial.

Costa C, Molina MA, Drozdowskyj A, Giménez-Capitán A, Bertran-Alamillo J, Karachaliou N, Gervais R, Massuti B, Wei J, Moran T, Majem M, Felip E, Carcereny E, Garcia-Campelo R, Viteri S, Taron M, Ono M, Giannikopoulos P, Bivona T, Rosell R.

Clin Cancer Res. 2014 Apr 1;20(7):2001-10. doi: 10.1158/1078-0432.CCR-13-2233. Epub 2014 Feb 3.


The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism.

Lee JH, Giannikopoulos P, Duncan SA, Wang J, Johansen CT, Brown JD, Plutzky J, Hegele RA, Glimcher LH, Lee AH.

Nat Med. 2011 Jun 12;17(7):812-5. doi: 10.1038/nm.2347.


Prenatal diagnosis of primary pulmonary hypoplasia in fraternal twins.

Chen S, Ursell PC, Adatia I, Hislop AA, Giannikopoulos P, Hornberger LK.

Ultrasound Obstet Gynecol. 2010 Jan;35(1):113-6. doi: 10.1002/uog.7520.


A case report of Noonan's syndrome with pulmonary valvar stenosis and coronary aneurysms.

Loukas M, Dabrowski M, Kantoch M, Ruzyłło W, Waltenberger J, Giannikopoulos P.

Med Sci Monit. 2004 Dec;10(12):CS80-3.


A retroesophageal right subclavian artery originating from the left aortic arch -- a case report and review of the literature.

Loukas M, Giannikopoulos P, Fudalej M, Dimopoulos C, Wagner T.

Folia Morphol (Warsz). 2004 Feb;63(1):141-5.


Binding to cisplatin-modified DNA by the Saccharomyces cerevisiae HMGB protein Nhp6A.

Wong B, Masse JE, Yen YM, Giannikopoulos P, Feigon J, Johnson RC.

Biochemistry. 2002 Apr 30;41(17):5404-14. Erratum in: Biochemistry 2002 Aug 6;41(31):10182. Giannikoupolous Petros [corrected to Giannikopoulos Petros].


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