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Items: 1 to 50 of 75


Enzyme-Responsive Polymer Nanoparticles via Ring-Opening Metathesis Polymerization-Induced Self-Assembly.

Wright DB, Thompson MP, Touve MA, Carlini AS, Gianneschi NC.

Macromol Rapid Commun. 2018 Sep 3:e1800467. doi: 10.1002/marc.201800467. [Epub ahead of print]


Seeded growth of single-crystal two-dimensional covalent organic frameworks.

Evans AM, Parent LR, Flanders NC, Bisbey RP, Vitaku E, Kirschner MS, Schaller RD, Chen LX, Gianneschi NC, Dichtel WR.

Science. 2018 Jul 6;361(6397):52-57. doi: 10.1126/science.aar7883. Epub 2018 Jun 21.


Polymerization-Induced Self-Assembly of Micelles Observed by Liquid Cell Transmission Electron Microscopy.

Touve MA, Figg CA, Wright DB, Park C, Cantlon J, Sumerlin BS, Gianneschi NC.

ACS Cent Sci. 2018 May 23;4(5):543-547. doi: 10.1021/acscentsci.8b00148. Epub 2018 Apr 25.


Multi-Scale Responses of Liquid Crystals Triggered by Interfacial Assemblies of Cleavable Homopolymers.

Kim YK, Huang Y, Tsuei M, Wang X, Gianneschi NC, Abbott NL.

Chemphyschem. 2018 Apr 22. doi: 10.1002/cphc.201800106. [Epub ahead of print]


Self-Transfecting Micellar RNA: Modulating Nanoparticle Cell Interactions via High Density Display of Small Molecule Ligands on Micelle Coronas.

Roloff A, Nelles DA, Thompson MP, Yeo GW, Gianneschi NC.

Bioconjug Chem. 2018 Jan 17;29(1):126-135. doi: 10.1021/acs.bioconjchem.7b00657. Epub 2017 Dec 29.


Transmission Electron Microscopy Reveals Deposition of Metal Oxide Coatings onto Metal-Organic Frameworks.

Denny MS Jr, Parent LR, Patterson JP, Meena SK, Pham H, Abellan P, Ramasse QM, Paesani F, Gianneschi NC, Cohen SM.

J Am Chem Soc. 2018 Jan 31;140(4):1348-1357. doi: 10.1021/jacs.7b10453. Epub 2018 Jan 18.


Tackling the Challenges of Dynamic Experiments Using Liquid-Cell Transmission Electron Microscopy.

Parent LR, Bakalis E, Proetto M, Li Y, Park C, Zerbetto F, Gianneschi NC.

Acc Chem Res. 2018 Jan 16;51(1):3-11. doi: 10.1021/acs.accounts.7b00331. Epub 2017 Dec 11.


Directly Observing Micelle Fusion and Growth in Solution by Liquid-Cell Transmission Electron Microscopy.

Parent LR, Bakalis E, Ramírez-Hernández A, Kammeyer JK, Park C, de Pablo J, Zerbetto F, Patterson JP, Gianneschi NC.

J Am Chem Soc. 2017 Nov 29;139(47):17140-17151. doi: 10.1021/jacs.7b09060. Epub 2017 Nov 17.


Lipogels for Encapsulation of Hydrophilic Proteins and Hydrophobic Small Molecules.

Homyak CC, Fernandez A, Touve MA, Zhao B, Anson F, Hardy JA, Vachet RW, Gianneschi NC, Ross JL, Thayumanavan S.

Biomacromolecules. 2018 Jan 8;19(1):132-140. doi: 10.1021/acs.biomac.7b01300. Epub 2017 Dec 15.


Micellar Thrombin-Binding Aptamers: Reversible Nanoscale Anticoagulants.

Roloff A, Carlini AS, Callmann CE, Gianneschi NC.

J Am Chem Soc. 2017 Nov 22;139(46):16442-16445. doi: 10.1021/jacs.7b07799. Epub 2017 Nov 14.


Enzyme-Targeted Nanoparticles for Delivery to Ischemic Skeletal Muscle.

Ungerleider JL, Kammeyer JK, Braden RL, Christman KL, Gianneschi NC.

Polym Chem. 2017 Sep 14;8(34):5212-5219. doi: 10.1039/C7PY00568G. Epub 2017 May 24.


High Relaxivity Gadolinium-Polydopamine Nanoparticles.

Wang Z, Carniato F, Xie Y, Huang Y, Li Y, He S, Zang N, Rinehart JD, Botta M, Gianneschi NC.

Small. 2017 Nov;13(43). doi: 10.1002/smll.201701830. Epub 2017 Oct 10.


Peptide Brush Polymers and Nanoparticles with Enzyme-Regulated Structure and Charge for Inducing or Evading Macrophage Cell Uptake.

Adamiak L, Touve MA, LeGuyader CLM, Gianneschi NC.

ACS Nano. 2017 Oct 24;11(10):9877-9888. doi: 10.1021/acsnano.7b03686. Epub 2017 Oct 3.


Pore Breathing of Metal-Organic Frameworks by Environmental Transmission Electron Microscopy.

Parent LR, Pham CH, Patterson JP, Denny MS Jr, Cohen SM, Gianneschi NC, Paesani F.

J Am Chem Soc. 2017 Oct 11;139(40):13973-13976. doi: 10.1021/jacs.7b06585. Epub 2017 Sep 27.


Bioinspired bright noniridescent photonic melanin supraballs.

Xiao M, Hu Z, Wang Z, Li Y, Tormo AD, Le Thomas N, Wang B, Gianneschi NC, Shawkey MD, Dhinojwala A.

Sci Adv. 2017 Sep 15;3(9):e1701151. doi: 10.1126/sciadv.1701151. eCollection 2017 Sep.


Mimicking Melanosomes: Polydopamine Nanoparticles as Artificial Microparasols.

Huang Y, Li Y, Hu Z, Yue X, Proetto MT, Jones Y, Gianneschi NC.

ACS Cent Sci. 2017 Jun 28;3(6):564-569. doi: 10.1021/acscentsci.6b00230. Epub 2017 May 18.


Charged Macromolecular Rhenium Bipyridine Catalysts with Tunable CO2 Reduction Potentials.

Sahu S, Cheung PL, Machan CW, Chabolla SA, Kubiak CP, Gianneschi NC.

Chemistry. 2017 Jun 27;23(36):8619-8622. doi: 10.1002/chem.201701901. Epub 2017 Jun 5.


Bio-inspired CO2 reduction by a rhenium tricarbonyl bipyridine-based catalyst appended to amino acids and peptidic platforms: incorporating proton relays and hydrogen-bonding functional groups.

Chabolla SA, Machan CW, Yin J, Dellamary EA, Sahu S, Gianneschi NC, Gilson MK, Tezcan FA, Kubiak CP.

Faraday Discuss. 2017 Jun 2;198:279-300. doi: 10.1039/c7fd00003k.


Enzyme-Responsive Nanoparticles for the Treatment of Disease.

Callmann CE, Gianneschi NC.

Methods Mol Biol. 2017;1570:223-238. doi: 10.1007/978-1-4939-6840-4_15.


Characterization of drug encapsulation and retention in archaea-inspired tetraether liposomes.

Leriche G, Cifelli JL, Sibucao KC, Patterson JP, Koyanagi T, Gianneschi NC, Yang J.

Org Biomol Chem. 2017 Mar 8;15(10):2157-2162. doi: 10.1039/c6ob02832b.


Colloidal Covalent Organic Frameworks.

Smith BJ, Parent LR, Overholts AC, Beaucage PA, Bisbey RP, Chavez AD, Hwang N, Park C, Evans AM, Gianneschi NC, Dichtel WR.

ACS Cent Sci. 2017 Jan 25;3(1):58-65. doi: 10.1021/acscentsci.6b00331. Epub 2017 Jan 12.


Polymer-Stabilized Perfluorobutane Nanodroplets for Ultrasound Imaging Agents.

Huang Y, Vezeridis AM, Wang J, Wang Z, Thompson M, Mattrey RF, Gianneschi NC.

J Am Chem Soc. 2017 Jan 11;139(1):15-18. doi: 10.1021/jacs.6b08800. Epub 2016 Dec 29.


Structure and Function of Iron-Loaded Synthetic Melanin.

Li Y, Xie Y, Wang Z, Zang N, Carniato F, Huang Y, Andolina CM, Parent LR, Ditri TB, Walter ED, Botta M, Rinehart JD, Gianneschi NC.

ACS Nano. 2016 Nov 22;10(11):10186-10194. Epub 2016 Nov 1.


Fluorocarbon Modified Low-Molecular-Weight Polyethylenimine for siRNA Delivery.

Johnson ME, Shon J, Guan BM, Patterson JP, Oldenhuis NJ, Eldredge AC, Gianneschi NC, Guan Z.

Bioconjug Chem. 2016 Aug 17;27(8):1784-8. doi: 10.1021/acs.bioconjchem.6b00216. Epub 2016 Jul 29.


Biosynthetic Polymers as Functional Materials.

Carlini AS, Adamiak L, Gianneschi NC.

Macromolecules. 2016 Jun 28;49(12):4379-4394. Epub 2016 Jun 21. Review.


Polymeric Gd-DOTA amphiphiles form spherical and fibril-shaped nanoparticle MRI contrast agents.

Randolph LM, LeGuyader CLM, Hahn ME, Andolina CM, Patterson JP, Mattrey RF, Millstone JE, Botta M, Scadeng M, Gianneschi NC.

Chem Sci. 2016 Jul 1;7(7):4230-4236. doi: 10.1039/c6sc00342g. Epub 2016 Mar 22.


Picoliter Drop-On-Demand Dispensing for Multiplex Liquid Cell Transmission Electron Microscopy.

Patterson JP, Parent LR, Cantlon J, Eickhoff H, Bared G, Evans JE, Gianneschi NC.

Microsc Microanal. 2016 Jun;22(3):507-14. doi: 10.1017/S1431927616000659. Epub 2016 May 3.


Cellular Delivery of Nanoparticles Revealed with Combined Optical and Isotopic Nanoscopy.

Proetto MT, Anderton CR, Hu D, Szymanski CJ, Zhu Z, Patterson JP, Kammeyer JK, Nilewski LG, Rush AM, Bell NC, Evans JE, Orr G, Howell SB, Gianneschi NC.

ACS Nano. 2016 Apr 26;10(4):4046-54. doi: 10.1021/acsnano.5b06477. Epub 2016 Mar 29.


Activating Peptides for Cellular Uptake via Polymerization into High Density Brushes.

Blum AP, Kammeyer JK, Gianneschi NC.

Chem Sci. 2016 Feb 1;7(2):989-994. doi: 10.1039/C5SC03417E. Epub 2015 Nov 10.


Blending block copolymer micelles in solution; Obstacles of blending.

Wright DB, Patterson JP, Gianneschi NC, Chassenieux C, Colombani O, O'Reilly RK.

Polym Chem. 2016 Feb 28;7(8):1577-1583. Epub 2016 Jan 26.


Sea Spray Aerosol Structure and Composition Using Cryogenic Transmission Electron Microscopy.

Patterson JP, Collins DB, Michaud JM, Axson JL, Sultana CM, Moser T, Dommer AC, Conner J, Grassian VH, Stokes MD, Deane GB, Evans JE, Burkart MD, Prather KA, Gianneschi NC.

ACS Cent Sci. 2016 Jan 27;2(1):40-47. Epub 2016 Jan 15.


Dual-responsive nanoparticles release cargo upon exposure to matrix metalloproteinase and reactive oxygen species.

Daniel KB, Callmann CE, Gianneschi NC, Cohen SM.

Chem Commun (Camb). 2016 Feb 4;52(10):2126-8. doi: 10.1039/c5cc09164k.


Polycatechol Nanoparticle MRI Contrast Agents.

Li Y, Huang Y, Wang Z, Carniato F, Xie Y, Patterson JP, Thompson MP, Andolina CM, Ditri TB, Millstone JE, Figueroa JS, Rinehart JD, Scadeng M, Botta M, Gianneschi NC.

Small. 2016 Feb 3;12(5):668-77. doi: 10.1002/smll.201502754. Epub 2015 Dec 17.


Dual responsive polymeric nanoparticles prepared by direct functionalization of polylactic acid-based polymers via graft-from ring opening metathesis polymerization.

Veccharelli KM, Tong VK, Young JL, Yang J, Gianneschi NC.

Chem Commun (Camb). 2016 Jan 11;52(3):567-70. doi: 10.1039/c5cc07882b. Epub 2015 Nov 6.


Enzyme-regulated topology of a cyclic peptide brush polymer for tuning assembly.

Wang Z, Li Y, Huang Y, Thompson MP, LeGuyader CL, Sahu S, Gianneschi NC.

Chem Commun (Camb). 2015 Dec 14;51(96):17108-11. doi: 10.1039/c5cc05653e.


Liquid Crystal Interfaces Programmed with Enzyme-Responsive Polymers and Surfactants.

Ma CD, Adamiak L, Miller DS, Wang X, Gianneschi NC, Abbott NL.

Small. 2015 Nov 18;11(43):5747-51. doi: 10.1002/smll.201502137. Epub 2015 Sep 29.


Enzyme-Responsive Nanoparticles for Targeted Accumulation and Prolonged Retention in Heart Tissue after Myocardial Infarction.

Nguyen MM, Carlini AS, Chien MP, Sonnenberg S, Luo C, Braden RL, Osborn KG, Li Y, Gianneschi NC, Christman KL.

Adv Mater. 2015 Oct 7;27(37):5547-52. doi: 10.1002/adma.201502003. Epub 2015 Aug 25.


Dye Encapsulation in Polynorbornene Micelles.

Bell NC, Doyle SJ, Battistelli G, LeGuyader CL, Thompson MP, Poe AM, Rheingold A, Moore C, Montalti M, Thayumanavan S, Tauber MJ, Gianneschi NC.

Langmuir. 2015 Sep 8;31(35):9707-17. doi: 10.1021/acs.langmuir.5b01822. Epub 2015 Aug 25.


Therapeutic Enzyme-Responsive Nanoparticles for Targeted Delivery and Accumulation in Tumors.

Callmann CE, Barback CV, Thompson MP, Hall DJ, Mattrey RF, Gianneschi NC.

Adv Mater. 2015 Aug 19;27(31):4611-5. doi: 10.1002/adma.201501803. Epub 2015 Jul 14.


Observing the growth of metal-organic frameworks by in situ liquid cell transmission electron microscopy.

Patterson JP, Abellan P, Denny MS Jr, Park C, Browning ND, Cohen SM, Evans JE, Gianneschi NC.

J Am Chem Soc. 2015 Jun 17;137(23):7322-8. doi: 10.1021/jacs.5b00817. Epub 2015 Jun 8.


Bio-Inspired Structural Colors Produced via Self-Assembly of Synthetic Melanin Nanoparticles.

Xiao M, Li Y, Allen MC, Deheyn DD, Yue X, Zhao J, Gianneschi NC, Shawkey MD, Dhinojwala A.

ACS Nano. 2015 May 26;9(5):5454-60. doi: 10.1021/acsnano.5b01298. Epub 2015 May 12.


Developing injectable nanomaterials to repair the heart.

Nguyen MM, Gianneschi NC, Christman KL.

Curr Opin Biotechnol. 2015 Aug;34:225-31. doi: 10.1016/j.copbio.2015.03.016. Epub 2015 Apr 11. Review.


Stimuli-responsive nanomaterials for biomedical applications.

Blum AP, Kammeyer JK, Rush AM, Callmann CE, Hahn ME, Gianneschi NC.

J Am Chem Soc. 2015 Feb 18;137(6):2140-54. doi: 10.1021/ja510147n. Epub 2015 Feb 6.


Tapping a bacterial enzymatic pathway for the preparation and manipulation of synthetic nanomaterials.

Ku TH, Sahu S, Kosa NM, Pham KM, Burkart MD, Gianneschi NC.

J Am Chem Soc. 2014 Dec 17;136(50):17378-81. doi: 10.1021/ja509827s. Epub 2014 Dec 3.


Peptides displayed as high density brush polymers resist proteolysis and retain bioactivity.

Blum AP, Kammeyer JK, Yin J, Crystal DT, Rush AM, Gilson MK, Gianneschi NC.

J Am Chem Soc. 2014 Oct 29;136(43):15422-37. doi: 10.1021/ja5088216. Epub 2014 Oct 14.



James CR, Rush AM, Insley T, Vuković L, Adamiak L, Král P, Gianneschi NC.

J Am Chem Soc. 2014 Aug 13;136(32):11216-9. doi: 10.1021/ja503142s. Epub 2014 Jul 31.


Labelling Polymers and Micellar Nanoparticles via Initiation, Propagation and Termination with ROMP.

Thompson MP, Randolph LM, James CR, Davalos AN, Hahn ME, Gianneschi NC.

Polym Chem. 2014 Mar 21;5(6):1954-1964.


Intracellular mRNA regulation with self-assembled locked nucleic acid polymer nanoparticles.

Rush AM, Nelles DA, Blum AP, Barnhill SA, Tatro ET, Yeo GW, Gianneschi NC.

J Am Chem Soc. 2014 May 28;136(21):7615-8. doi: 10.1021/ja503598z. Epub 2014 May 14.


Dynamics of soft nanomaterials captured by transmission electron microscopy in liquid water.

Proetto MT, Rush AM, Chien MP, Abellan Baeza P, Patterson JP, Thompson MP, Olson NH, Moore CE, Rheingold AL, Andolina C, Millstone J, Howell SB, Browning ND, Evans JE, Gianneschi NC.

J Am Chem Soc. 2014 Jan 29;136(4):1162-5. doi: 10.1021/ja408513m. Epub 2014 Jan 14.


Calcium phosphate-bearing matrices induce osteogenic differentiation of stem cells through adenosine signaling.

Shih YR, Hwang Y, Phadke A, Kang H, Hwang NS, Caro EJ, Nguyen S, Siu M, Theodorakis EA, Gianneschi NC, Vecchio KS, Chien S, Lee OK, Varghese S.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):990-5. doi: 10.1073/pnas.1321717111. Epub 2014 Jan 6.

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