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Items: 1 to 50 of 118

1.

A silver lining for 24-hydroxycholesterol in Alzheimer's disease: The involvement of the neuroprotective enzyme sirtuin 1.

Testa G, Staurenghi E, Giannelli S, Gargiulo S, Guglielmotto M, Tabaton M, Tamagno E, Gamba P, Leonarduzzi G.

Redox Biol. 2018 Jul;17:423-431. doi: 10.1016/j.redox.2018.05.009. Epub 2018 May 22.

2.

Gene therapy in rare diseases: the benefits and challenges of developing a patient-centric registry for Strimvelis in ADA-SCID.

Stirnadel-Farrant H, Kudari M, Garman N, Imrie J, Chopra B, Giannelli S, Gabaldo M, Corti A, Zancan S, Aiuti A, Cicalese MP, Batta R, Appleby J, Davinelli M, Ng P.

Orphanet J Rare Dis. 2018 Apr 6;13(1):49. doi: 10.1186/s13023-018-0791-9.

3.

Cas9/sgRNA selective targeting of the P23H Rhodopsin mutant allele for treating retinitis pigmentosa by intravitreal AAV9.PHP.B-based delivery.

Giannelli SG, Luoni M, Castoldi V, Massimino L, Cabassi T, Angeloni D, Demontis GC, Leocani L, Andreazzoli M, Broccoli V.

Hum Mol Genet. 2018 Mar 1;27(5):761-779. doi: 10.1093/hmg/ddx438.

PMID:
29281027
4.

The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways.

Sessa A, Ciabatti E, Drechsel D, Massimino L, Colasante G, Giannelli S, Satoh T, Akira S, Guillemot F, Broccoli V.

Cereb Cortex. 2017 Dec 1;27(12):5715. doi: 10.1093/cercor/bhx209. No abstract available.

PMID:
28968796
5.

AAV-PHP.B-Mediated Global-Scale Expression in the Mouse Nervous System Enables GBA1 Gene Therapy for Wide Protection from Synucleinopathy.

Morabito G, Giannelli SG, Ordazzo G, Bido S, Castoldi V, Indrigo M, Cabassi T, Cattaneo S, Luoni M, Cancellieri C, Sessa A, Bacigaluppi M, Taverna S, Leocani L, Lanciego JL, Broccoli V.

Mol Ther. 2017 Dec 6;25(12):2727-2742. doi: 10.1016/j.ymthe.2017.08.004. Epub 2017 Aug 10.

PMID:
28882452
6.

Generation of Human Induced Pluripotent Stem Cell-Derived Bona Fide Neural Stem Cells for Ex Vivo Gene Therapy of Metachromatic Leukodystrophy.

Meneghini V, Frati G, Sala D, De Cicco S, Luciani M, Cavazzin C, Paulis M, Mentzen W, Morena F, Giannelli S, Sanvito F, Villa A, Bulfone A, Broccoli V, Martino S, Gritti A.

Stem Cells Transl Med. 2017 Feb;6(2):352-368. doi: 10.5966/sctm.2015-0414. Epub 2016 Sep 16.

7.

Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells.

Mazzara PG, Massimino L, Pellegatta M, Ronchi G, Ricca A, Iannielli A, Giannelli SG, Cursi M, Cancellieri C, Sessa A, Del Carro U, Quattrini A, Geuna S, Gritti A, Taveggia C, Broccoli V.

Nat Commun. 2017 Feb 7;8:14088. doi: 10.1038/ncomms14088.

8.

Rapid and efficient CRISPR/Cas9 gene inactivation in human neurons during human pluripotent stem cell differentiation and direct reprogramming.

Rubio A, Luoni M, Giannelli SG, Radice I, Iannielli A, Cancellieri C, Di Berardino C, Regalia G, Lazzari G, Menegon A, Taverna S, Broccoli V.

Sci Rep. 2016 Nov 18;6:37540. doi: 10.1038/srep37540.

9.

Large Deletion of MAGT1 Gene in a Patient with Classic Kaposi Sarcoma, CD4 Lymphopenia, and EBV Infection.

Brigida I, Chiriaco M, Di Cesare S, Cittaro D, Di Matteo G, Giannelli S, Lazarevic D, Zoccolillo M, Stupka E, Jenkner A, Francalanci P, Livadiotti S, Morawski A, Ravell J, Lenardo M, Cancrini C, Aiuti A, Finocchi A.

J Clin Immunol. 2017 Jan;37(1):32-35. doi: 10.1007/s10875-016-0341-y. Epub 2016 Oct 21. No abstract available.

10.

The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways.

Sessa A, Ciabatti E, Drechsel D, Massimino L, Colasante G, Giannelli S, Satoh T, Akira S, Guillemot F, Broccoli V.

Cereb Cortex. 2017 Jun 1;27(6):3378-3396. doi: 10.1093/cercor/bhw270.

PMID:
27600842
11.

Coenzyme A corrects pathological defects in human neurons of PANK2-associated neurodegeneration.

Orellana DI, Santambrogio P, Rubio A, Yekhlef L, Cancellieri C, Dusi S, Giannelli SG, Venco P, Mazzara PG, Cozzi A, Ferrari M, Garavaglia B, Taverna S, Tiranti V, Broccoli V, Levi S.

EMBO Mol Med. 2016 Oct 4;8(10):1197-1211. doi: 10.15252/emmm.201606391. Print 2016 Oct.

12.

In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases.

Biasco L, Pellin D, Scala S, Dionisio F, Basso-Ricci L, Leonardelli L, Scaramuzza S, Baricordi C, Ferrua F, Cicalese MP, Giannelli S, Neduva V, Dow DJ, Schmidt M, Von Kalle C, Roncarolo MG, Ciceri F, Vicard P, Wit E, Di Serio C, Naldini L, Aiuti A.

Cell Stem Cell. 2016 Jul 7;19(1):107-19. doi: 10.1016/j.stem.2016.04.016. Epub 2016 May 26.

13.

Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency.

Cicalese MP, Ferrua F, Castagnaro L, Pajno R, Barzaghi F, Giannelli S, Dionisio F, Brigida I, Bonopane M, Casiraghi M, Tabucchi A, Carlucci F, Grunebaum E, Adeli M, Bredius RG, Puck JM, Stepensky P, Tezcan I, Rolfe K, De Boever E, Reinhardt RR, Appleby J, Ciceri F, Roncarolo MG, Aiuti A.

Blood. 2016 Jul 7;128(1):45-54. doi: 10.1182/blood-2016-01-688226. Epub 2016 Apr 29. Erratum in: Blood. 2017 Jun 15;129(24):3271.

14.

Hypnosis can reduce pain in hospitalized older patients: a randomized controlled study.

Ardigo S, Herrmann FR, Moret V, Déramé L, Giannelli S, Gold G, Pautex S.

BMC Geriatr. 2016 Jan 15;16:14. doi: 10.1186/s12877-016-0180-y.

15.

The case of an APDS patient: Defects in maturation and function and decreased in vitro anti-mycobacterial activity in the myeloid compartment.

Chiriaco M, Brigida I, Ariganello P, Di Cesare S, Di Matteo G, Taus F, Cittaro D, Lazarevic D, Scarselli A, Santilli V, Attardi E, Stupka E, Giannelli S, Fraziano M, Finocchi A, Rossi P, Aiuti A, Palma P, Cancrini C.

Clin Immunol. 2017 May;178:20-28. doi: 10.1016/j.clim.2015.12.008. Epub 2015 Dec 28.

PMID:
26732860
16.

Rapid Conversion of Fibroblasts into Functional Forebrain GABAergic Interneurons by Direct Genetic Reprogramming.

Colasante G, Lignani G, Rubio A, Medrihan L, Yekhlef L, Sessa A, Massimino L, Giannelli SG, Sacchetti S, Caiazzo M, Leo D, Alexopoulou D, Dell'Anno MT, Ciabatti E, Orlando M, Studer M, Dahl A, Gainetdinov RR, Taverna S, Benfenati F, Broccoli V.

Cell Stem Cell. 2015 Dec 3;17(6):719-734. doi: 10.1016/j.stem.2015.09.002. Epub 2015 Oct 29.

17.

In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells.

Biasco L, Scala S, Basso Ricci L, Dionisio F, Baricordi C, Calabria A, Giannelli S, Cieri N, Barzaghi F, Pajno R, Al-Mousa H, Scarselli A, Cancrini C, Bordignon C, Roncarolo MG, Montini E, Bonini C, Aiuti A.

Sci Transl Med. 2015 Feb 4;7(273):273ra13. doi: 10.1126/scitranslmed.3010314.

PMID:
25653219
18.

Ranolazine in the treatment of atrial fibrillation: Results of the dose-ranging RAFFAELLO (Ranolazine in Atrial Fibrillation Following An ELectricaL CardiOversion) study.

De Ferrari GM, Maier LS, Mont L, Schwartz PJ, Simonis G, Leschke M, Gronda E, Boriani G, Darius H, Guillamón Torán L, Savelieva I, Dusi V, Marchionni N, Quintana Rendón M, Schumacher K, Tonini G, Melani L, Giannelli S, Alberto Maggi C, Camm AJ; RAFFAELLO Investigators (see Online Supplementary Appendix for List of Participating Centers and Investigators).

Heart Rhythm. 2015 May;12(5):872-8. doi: 10.1016/j.hrthm.2015.01.021. Epub 2015 Jan 17.

PMID:
25602175
19.

Direct conversion of fibroblasts into functional astrocytes by defined transcription factors.

Caiazzo M, Giannelli S, Valente P, Lignani G, Carissimo A, Sessa A, Colasante G, Bartolomeo R, Massimino L, Ferroni S, Settembre C, Benfenati F, Broccoli V.

Stem Cell Reports. 2015 Jan 13;4(1):25-36. doi: 10.1016/j.stemcr.2014.12.002. Epub 2014 Dec 31.

20.

Modeling physiological and pathological human neurogenesis in the dish.

Broccoli V, Giannelli SG, Mazzara PG.

Front Neurosci. 2014 Jul 24;8:183. doi: 10.3389/fnins.2014.00183. eCollection 2014. Review.

21.

Remote control of induced dopaminergic neurons in parkinsonian rats.

Dell'Anno MT, Caiazzo M, Leo D, Dvoretskova E, Medrihan L, Colasante G, Giannelli S, Theka I, Russo G, Mus L, Pezzoli G, Gainetdinov RR, Benfenati F, Taverna S, Dityatev A, Broccoli V.

J Clin Invest. 2014 Jul;124(7):3215-29. doi: 10.1172/JCI74664. Epub 2014 Jun 17.

22.

Vitamin D is not associated with cognitive status in a cohort of very old hospitalized patients.

Graf CE, Rossi C, Giannelli SV, Nobari BH, Gold G, Herrmann FR, Zekry D.

J Alzheimers Dis. 2014;42 Suppl 3:S53-61. doi: 10.3233/JAD-132612.

PMID:
24898645
23.

Familial adenomatous polyposis-associated, cribriform morular variant of papillary thyroid carcinoma harboring a K-RAS mutation: case presentation and review of molecular mechanisms.

Giannelli SM, McPhaul L, Nakamoto J, Gianoukakis AG.

Thyroid. 2014 Jul;24(7):1184-9. doi: 10.1089/thy.2013.0589. Epub 2014 May 20.

PMID:
24702198
24.

B-cell development and functions and therapeutic options in adenosine deaminase-deficient patients.

Brigida I, Sauer AV, Ferrua F, Giannelli S, Scaramuzza S, Pistoia V, Castiello MC, Barendregt BH, Cicalese MP, Casiraghi M, Brombin C, Puck J, Müller K, Notarangelo LD, Montin D, van Montfrans JM, Roncarolo MG, Traggiai E, van Dongen JJ, van der Burg M, Aiuti A.

J Allergy Clin Immunol. 2014 Mar;133(3):799-806.e10. doi: 10.1016/j.jaci.2013.12.1043. Epub 2014 Feb 5.

25.

COUP-TFI controls activity-dependent tyrosine hydroxylase expression in adult dopaminergic olfactory bulb interneurons.

Bovetti S, Bonzano S, Garzotto D, Giannelli SG, Iannielli A, Armentano M, Studer M, De Marchis S.

Development. 2013 Dec;140(24):4850-9. doi: 10.1242/dev.089961. Epub 2013 Nov 13.

26.

Tooth loss, chewing efficiency and cognitive impairment in geriatric patients.

Elsig F, Schimmel M, Duvernay E, Giannelli SV, Graf CE, Carlier S, Herrmann FR, Michel JP, Gold G, Zekry D, Müller F.

Gerodontology. 2015 Jun;32(2):149-56. doi: 10.1111/ger.12079. Epub 2013 Oct 16.

PMID:
24128078
27.

Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.

Aiuti A, Biasco L, Scaramuzza S, Ferrua F, Cicalese MP, Baricordi C, Dionisio F, Calabria A, Giannelli S, Castiello MC, Bosticardo M, Evangelio C, Assanelli A, Casiraghi M, Di Nunzio S, Callegaro L, Benati C, Rizzardi P, Pellin D, Di Serio C, Schmidt M, Von Kalle C, Gardner J, Mehta N, Neduva V, Dow DJ, Galy A, Miniero R, Finocchi A, Metin A, Banerjee PP, Orange JS, Galimberti S, Valsecchi MG, Biffi A, Montini E, Villa A, Ciceri F, Roncarolo MG, Naldini L.

Science. 2013 Aug 23;341(6148):1233151. doi: 10.1126/science.1233151. Epub 2013 Jul 11.

28.

Lack of activation of peripheral blood dendritic cells in human pregnancies complicated by intrauterine growth restriction.

Cappelletti M, Giannelli S, Martinelli A, Cetin I, Colombo E, Calcaterra F, Mavilio D, Della Bella S.

Placenta. 2013 Jan;34(1):35-41. doi: 10.1016/j.placenta.2012.10.016. Epub 2012 Nov 22.

PMID:
23182380
29.

Can we improve the detection of old patients at higher risk for readmission after an emergency department visit?

Graf CE, Giannelli SV, Herrmann FR, Sarasin FP, Michel JP, Zekry D, Chevalley T.

J Am Geriatr Soc. 2012 Jul;60(7):1372-3. doi: 10.1111/j.1532-5415.2012.04026.x. No abstract available.

PMID:
22788397
30.

Identification of older patients at risk of unplanned readmission after discharge from the emergency department - comparison of two screening tools.

Graf CE, Giannelli SV, Herrmann FR, Sarasin FP, Michel JP, Zekry D, Chevalley T.

Swiss Med Wkly. 2012 Jan 3;141:w13327. doi: 10.4414/smw.2011.13327. eCollection 2012.

31.

Natural history of older adults with impaired kidney function: the InCHIANTI study.

Giannelli SV, Graf CE, Herrmann FR, Michel JP, Patel KV, Pizzarelli F, Ferrucci L, Guralnik J.

Rejuvenation Res. 2011 Oct;14(5):513-23. doi: 10.1089/rej.2011.1179. Epub 2011 Sep 28.

32.

High levels of comorbidity and disability cancel out the dementia effect in predictions of long-term mortality after discharge in the very old.

Zekry D, Herrmann FR, Graf CE, Giannelli S, Michel JP, Gold G, Krause KH.

Dement Geriatr Cogn Disord. 2011;32(2):103-10. doi: 10.1159/000326950. Epub 2011 Sep 23.

PMID:
21952417
33.

Adult human Müller glia cells are a highly efficient source of rod photoreceptors.

Giannelli SG, Demontis GC, Pertile G, Rama P, Broccoli V.

Stem Cells. 2011 Feb;29(2):344-56. doi: 10.1002/stem.579.

34.

Mild cognitive impairment, degenerative and vascular dementia as predictors of intra-hospital, short- and long-term mortality in the oldest old.

Zekry D, Herrmann FR, Graf CE, Giannelli S, Michel JP, Gold G, Krause KH.

Aging Clin Exp Res. 2011 Feb;23(1):60-6.

PMID:
21499020
35.

Incomplete activation of peripheral blood dendritic cells during healthy human pregnancy.

Della Bella S, Giannelli S, Cozzi V, Signorelli V, Cappelletti M, Cetin I, Villa ML.

Clin Exp Immunol. 2011 May;164(2):180-92. doi: 10.1111/j.1365-2249.2011.04330.x. Epub 2011 Feb 24.

36.

The prevalence, characteristics and metabolic consequences of renal insufficiency in very old hospitalized diabetic patients.

Vischer UM, Giannelli SV, Weiss L, Perrenoud L, Frangos E, Herrmann FR.

Diabetes Metab. 2011 Apr;37(2):131-8. doi: 10.1016/j.diabet.2010.08.007. Epub 2011 Jan 26.

PMID:
21273106
37.

Well differentiated follicular thyroid neoplasia: impact of molecular and technological advances on detection, monitoring and treatment.

Gianoukakis AG, Giannelli SM, Salameh WA, McPhaul LW.

Mol Cell Endocrinol. 2011 Jan 30;332(1-2):9-20. doi: 10.1016/j.mce.2010.11.009. Epub 2010 Nov 20. Review.

PMID:
21094678
38.

Efficiency and applicability of comprehensive geriatric assessment in the emergency department: a systematic review.

Graf CE, Zekry D, Giannelli S, Michel JP, Chevalley T.

Aging Clin Exp Res. 2011 Aug;23(4):244-54. doi: 10.3275/7284. Epub 2010 Oct 5. Review.

PMID:
20930499
39.

Comprehensive geriatric assessment in the emergency department.

Graf CE, Zekry D, Giannelli S, Michel JP, Chevalley T.

J Am Geriatr Soc. 2010 Oct;58(10):2032-3. doi: 10.1111/j.1532-5415.2010.03090.x. No abstract available.

PMID:
20929478
40.

Long-term culture and differentiation of CNS precursors derived from anterior human neural rosettes following exposure to ventralizing factors.

Colleoni S, Galli C, Giannelli SG, Armentero MT, Blandini F, Broccoli V, Lazzari G.

Exp Cell Res. 2010 Apr 15;316(7):1148-58. doi: 10.1016/j.yexcr.2010.02.013. Epub 2010 Feb 17.

PMID:
20171210
41.

Human defensins activate monocyte-derived dendritic cells, promote the production of proinflammatory cytokines, and up-regulate the surface expression of CD91.

Presicce P, Giannelli S, Taddeo A, Villa ML, Della Bella S.

J Leukoc Biol. 2009 Oct;86(4):941-8. doi: 10.1189/jlb.0708412.

PMID:
19477909
42.

You missed the 5th EUGMS Congress? All the things which you would have been able to learn!

Lang PO, Schmitt K, Cankurtaran M, Giannelli S, Blain H.

J Nutr Health Aging. 2009 Apr;13(4):396-400. No abstract available.

PMID:
19300889
43.

Predictivity of survival according to different equations for estimating renal function in community-dwelling elderly subjects.

Pizzarelli F, Lauretani F, Bandinelli S, Windham GB, Corsi AM, Giannelli SV, Ferrucci L, Guralnik JM.

Nephrol Dial Transplant. 2009 Apr;24(4):1197-205. doi: 10.1093/ndt/gfn594. Epub 2008 Nov 6.

44.

Application of six-color flow cytometry for the assessment of dendritic cell responses in whole blood assays.

Della Bella S, Giannelli S, Taddeo A, Presicce P, Villa ML.

J Immunol Methods. 2008 Dec 31;339(2):153-64. doi: 10.1016/j.jim.2008.09.009. Epub 2008 Oct 7.

PMID:
18835394
45.

Comparative value of medical diagnosis versus physical functioning in predicting the 6-year survival of 1951 hospitalized old patients.

Lordos EF, Herrmann FR, Robine JM, Balahoczky M, Giannelli SV, Gold G, Michel JP.

Rejuvenation Res. 2008 Aug;11(4):829-36. doi: 10.1089/rej.2008.0721. No abstract available.

PMID:
18729815
46.

A six-color flow cytometric assay for the analysis of peripheral blood dendritic cells.

Giannelli S, Taddeo A, Presicce P, Villa ML, Della Bella S.

Cytometry B Clin Cytom. 2008 Nov;74(6):349-55. doi: 10.1002/cyto.b.20434.

47.

Magnitude of underascertainment of impaired kidney function in older adults with normal serum creatinine.

Giannelli SV, Patel KV, Windham BG, Pizzarelli F, Ferrucci L, Guralnik JM.

J Am Geriatr Soc. 2007 Jun;55(6):816-23.

48.

Hypercortisolemic depression is associated with the metabolic syndrome in late-life.

Vogelzangs N, Suthers K, Ferrucci L, Simonsick EM, Ble A, Schrager M, Bandinelli S, Lauretani F, Giannelli SV, Penninx BW.

Psychoneuroendocrinology. 2007 Feb;32(2):151-9. Epub 2007 Jan 16.

49.

Direct derivation of neural rosettes from cloned bovine blastocysts: a model of early neurulation events and neural crest specification in vitro.

Lazzari G, Colleoni S, Giannelli SG, Brunetti D, Colombo E, Lagutina I, Galli C, Broccoli V.

Stem Cells. 2006 Nov;24(11):2514-21. Epub 2006 Aug 24.

50.

Neuromelanin and iron in human locus coeruleus and substantia nigra during aging: consequences for neuronal vulnerability.

Zucca FA, Bellei C, Giannelli S, Terreni MR, Gallorini M, Rizzio E, Pezzoli G, Albertini A, Zecca L.

J Neural Transm (Vienna). 2006 Jun;113(6):757-67. Epub 2006 Apr 28.

PMID:
16755380

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