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Items: 1 to 50 of 180

1.

Transforming Growth Factor-β Promotes Morphomechanical Effects Involved in Epithelial to Mesenchymal Transition in Living Hepatocellular Carcinoma.

Cascione M, Leporatti S, Dituri F, Giannelli G.

Int J Mol Sci. 2018 Dec 28;20(1). pii: E108. doi: 10.3390/ijms20010108.

2.

TGF-β as Multifaceted Orchestrator in HCC Progression: Signaling, EMT, Immune Microenvironment, and Novel Therapeutic Perspectives.

Dituri F, Mancarella S, Cigliano A, Chieti A, Giannelli G.

Semin Liver Dis. 2019 Feb;39(1):53-69. doi: 10.1055/s-0038-1676121. Epub 2018 Dec 26.

PMID:
30586675
3.

Aquaporin 9 Contributes to the Maturation Process and Inflammatory Cytokine Secretion of Murine Dendritic Cells.

De Santis S, Fiorentino MR, Galleggiante V, Verna G, Liso M, Massaro M, Lan J, Troisi J, Bertamino A, Pinto A, Campiglia P, Santino A, Giannelli G, Fasano A, Serino G, Chieppa M.

Front Immunol. 2018 Oct 16;9:2355. doi: 10.3389/fimmu.2018.02355. eCollection 2018.

4.

Key Enabling Technologies for Point-of-Care Diagnostics.

Primiceri E, Chiriacò MS, Notarangelo FM, Crocamo A, Ardissino D, Cereda M, Bramanti AP, Bianchessi MA, Giannelli G, Maruccio G.

Sensors (Basel). 2018 Oct 24;18(11). pii: E3607. doi: 10.3390/s18113607. Review.

5.

Epigenetic upregulation and functional role of the mitochondrial aspartate/glutamate carrier isoform 1 in hepatocellular carcinoma.

Infantino V, Dituri F, Convertini P, Santarsiero A, Palmieri F, Todisco S, Mancarella S, Giannelli G, Iacobazzi V.

Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):38-47. doi: 10.1016/j.bbadis.2018.10.018. Epub 2018 Oct 12.

PMID:
30321589
6.

BACE inhibitors in clinical development for the treatment of Alzheimer's disease.

Panza F, Lozupone M, Solfrizzi V, Sardone R, Piccininni C, Dibello V, Stallone R, Giannelli G, Bellomo A, Greco A, Daniele A, Seripa D, Logroscino G, Imbimbo BP.

Expert Rev Neurother. 2018 Nov;18(11):847-857. doi: 10.1080/14737175.2018.1531706. Epub 2018 Oct 24.

PMID:
30277096
7.

Aerobic Physical Activity and a Low Glycemic Diet Reduce the AA/EPA Ratio in Red Blood Cell Membranes of Patients with NAFLD.

Tutino V, De Nunzio V, Caruso MG, Bonfiglio C, Franco I, Mirizzi A, De Leonardis G, Cozzolongo R, Giannuzzi V, Giannelli G, Notarnicola M, Osella AR.

Nutrients. 2018 Sep 13;10(9). pii: E1299. doi: 10.3390/nu10091299.

8.

Social Dysfunction in Older Age and Relationships with Cognition, Depression, and Apathy: The GreatAGE Study.

Lozupone M, Panza F, Piccininni M, Copetti M, Sardone R, Imbimbo BP, Stella E, D'Urso F, Barulli MR, Battista P, Grasso A, Tortelli R, Capozzo R, Coppola F, Abbrescia DI, Bellomo A, Giannelli G, Quaranta N, Seripa D, Logroscino G.

J Alzheimers Dis. 2018;65(3):989-1000. doi: 10.3233/JAD-180466.

PMID:
30103335
9.

Irisin Serum Levels in Metabolic Syndrome Patients Treated with Three Different Diets: A Post-Hoc Analysis from a Randomized Controlled Clinical Trial.

Osella AR, Colaianni G, Correale M, Pesole PL, Bruno I, Buongiorno C, Deflorio V, Leone CM, Colucci SC, Grano M, Giannelli G.

Nutrients. 2018 Jun 28;10(7). pii: E844. doi: 10.3390/nu10070844.

10.

Plasma cholesterol and lipoprotein levels in relation to tumor aggressiveness and survival in HCC patients.

Carr BI, Giannelli G, Guerra V, Giannini EG, Farinati F, Rapaccini GL, Marco MD, Zoli M, Caturelli E, Masotto A, Virdone R, Sacco R, Trevisani F.

Int J Biol Markers. 2018 Nov;33(4):423-431. doi: 10.1177/1724600818776838. Epub 2018 Jun 6.

PMID:
29874983
11.

Galunisertib modifies the liver fibrotic composition in the Abcb4Ko mouse model.

Hammad S, Cavalcanti E, Werle J, Caruso ML, Dropmann A, Ignazzi A, Ebert MP, Dooley S, Giannelli G.

Arch Toxicol. 2018 Jul;92(7):2297-2309. doi: 10.1007/s00204-018-2231-y. Epub 2018 May 28.

PMID:
29808285
12.

Pharmacotherapy for the treatment of depression in patients with alzheimer's disease: a treatment-resistant depressive disorder.

Lozupone M, La Montagna M, D'Urso F, Piccininni C, Sardone R, Dibello V, Giannelli G, Solfrizzi V, Greco A, Daniele A, Quaranta N, Seripa D, Bellomo A, Logroscino G, Panza F.

Expert Opin Pharmacother. 2018 Jun;19(8):823-842. doi: 10.1080/14656566.2018.1471136. Epub 2018 May 4. Review.

PMID:
29726758
13.

Immune Cells and Microbiota Response to Iron Starvation.

Chieppa M, Giannelli G.

Front Med (Lausanne). 2018 Apr 18;5:109. doi: 10.3389/fmed.2018.00109. eCollection 2018.

14.

TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer.

Caja L, Dituri F, Mancarella S, Caballero-Diaz D, Moustakas A, Giannelli G, Fabregat I.

Int J Mol Sci. 2018 Apr 26;19(5). pii: E1294. doi: 10.3390/ijms19051294. Review.

15.

Liver Angiopoietin-2 Is a Key Predictor of De Novo or Recurrent Hepatocellular Cancer After Hepatitis C Virus Direct-Acting Antivirals.

Faillaci F, Marzi L, Critelli R, Milosa F, Schepis F, Turola E, Andreani S, Vandelli G, Bernabucci V, Lei B, D'Ambrosio F, Bristot L, Cavalletto L, Chemello L, Sighinolfi P, Manni P, Maiorana A, Caporali C, Bianchini M, Marsico M, Turco L, de Maria N, Del Buono M, Todesca P, di Lena L, Romagnoli D, Magistri P, di Benedetto F, Bruno S, Taliani G, Giannelli G, Martinez-Chantar ML, Villa E.

Hepatology. 2018 Sep;68(3):1010-1024. doi: 10.1002/hep.29911.

16.

Differential Tissue Fatty Acids Profiling between Colorectal Cancer Patients with and without Synchronous Metastasis.

Notarnicola M, Lorusso D, Tutino V, De Nunzio V, De Leonardis G, Marangelli G, Guerra V, Veronese N, Caruso MG, Giannelli G.

Int J Mol Sci. 2018 Mar 23;19(4). pii: E962. doi: 10.3390/ijms19040962.

17.

Dietary fiber and health outcomes: an umbrella review of systematic reviews and meta-analyses.

Veronese N, Solmi M, Caruso MG, Giannelli G, Osella AR, Evangelou E, Maggi S, Fontana L, Stubbs B, Tzoulaki I.

Am J Clin Nutr. 2018 Mar 1;107(3):436-444. doi: 10.1093/ajcn/nqx082.

PMID:
29566200
18.

Different Cognitive Frailty Models and Health- and Cognitive-related Outcomes in Older Age: From Epidemiology to Prevention.

Panza F, Lozupone M, Solfrizzi V, Sardone R, Dibello V, Di Lena L, D'Urso F, Stallone R, Petruzzi M, Giannelli G, Quaranta N, Bellomo A, Greco A, Daniele A, Seripa D, Logroscino G.

J Alzheimers Dis. 2018;62(3):993-1012. doi: 10.3233/JAD-170963.

19.

Galunisertib suppresses the staminal phenotype in hepatocellular carcinoma by modulating CD44 expression.

Rani B, Malfettone A, Dituri F, Soukupova J, Lupo L, Mancarella S, Fabregat I, Giannelli G.

Cell Death Dis. 2018 Mar 7;9(3):373. doi: 10.1038/s41419-018-0384-5.

20.

Polymeric Nano-Micelles as Novel Cargo-Carriers for LY2157299 Liver Cancer Cells Delivery.

Hanafy NAN, Quarta A, Ferraro MM, Dini L, Nobile C, De Giorgi ML, Carallo S, Citti C, Gaballo A, Cannazza G, Rinaldi R, Giannelli G, Leporatti S.

Int J Mol Sci. 2018 Mar 6;19(3). pii: E748. doi: 10.3390/ijms19030748.

21.

PD-L1 expression in colorectal cancer defines three subsets of tumor immune microenvironments.

Valentini AM, Di Pinto F, Cariola F, Guerra V, Giannelli G, Caruso ML, Pirrelli M.

Oncotarget. 2018 Jan 12;9(9):8584-8596. doi: 10.18632/oncotarget.24196. eCollection 2018 Feb 2.

22.

Coffee Intake and Liver Steatosis: A Population Study in a Mediterranean Area.

Veronese N, Notarnicola M, Cisternino AM, Reddavide R, Inguaggiato R, Guerra V, Rotolo O, Zinzi I, Leandro G, Correale M, Tutino V, Misciagna G, Osella AR, Bonfiglio C, Giannelli G, Caruso MG; MICOL Group.

Nutrients. 2018 Jan 15;10(1). pii: E89. doi: 10.3390/nu10010089.

23.

Developmental Exposure to Low Levels of Ethinylestradiol Affects Play Behavior in Juvenile Female Rats.

Zaccaroni M, Massolo A, Della Seta D, Farabollini F, Giannelli G, Fusani L, Dessì-Fulgheri F.

Neurotox Res. 2018 May;33(4):876-886. doi: 10.1007/s12640-017-9852-4. Epub 2017 Dec 19.

PMID:
29260494
24.

Role of the Transforming Growth Factor-β in regulating hepatocellular carcinoma oxidative metabolism.

Soukupova J, Malfettone A, Hyroššová P, Hernández-Alvarez MI, Peñuelas-Haro I, Bertran E, Junza A, Capellades J, Giannelli G, Yanes O, Zorzano A, Perales JC, Fabregat I.

Sci Rep. 2017 Oct 2;7(1):12486. doi: 10.1038/s41598-017-12837-y.

25.

Innovative biomarkers in psychiatric disorders: a major clinical challenge in psychiatry.

Lozupone M, Seripa D, Stella E, La Montagna M, Solfrizzi V, Quaranta N, Veneziani F, Cester A, Sardone R, Bonfiglio C, Giannelli G, Bisceglia P, Bringiotti R, Daniele A, Greco A, Bellomo A, Logroscino G, Panza F.

Expert Rev Proteomics. 2017 Sep;14(9):809-824. doi: 10.1080/14789450.2017.1375857. Epub 2017 Sep 11. Review.

PMID:
28870126
26.

Microenvironment inflammatory infiltrate drives growth speed and outcome of hepatocellular carcinoma: a prospective clinical study.

Critelli R, Milosa F, Faillaci F, Condello R, Turola E, Marzi L, Lei B, Dituri F, Andreani S, Sighinolfi P, Manni P, Maiorana A, Caporali C, di Benedetto F, Del Buono M, De Maria N, Schepis F, Martinez-Chantar ML, Giannelli G, Villa E.

Cell Death Dis. 2017 Aug 24;8(8):e3017. doi: 10.1038/cddis.2017.395.

27.

Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice.

Zhang S, Song X, Cao D, Xu Z, Fan B, Che L, Hu J, Chen B, Dong M, Pilo MG, Cigliano A, Evert K, Ribback S, Dombrowski F, Pascale RM, Cossu A, Vidili G, Porcu A, Simile MM, Pes GM, Giannelli G, Gordan J, Wei L, Evert M, Cong W, Calvisi DF, Chen X.

J Hepatol. 2017 Dec;67(6):1194-1203. doi: 10.1016/j.jhep.2017.07.006. Epub 2017 Jul 19.

28.

Precision medicine for hepatocelluar carcinoma using molecular pattern diagnostics: results from a preclinical pilot study.

Agarwal R, Cao Y, Hoffmeier K, Krezdorn N, Jost L, Meisel AR, Jüngling R, Dituri F, Mancarella S, Rotter B, Winter P, Giannelli G.

Cell Death Dis. 2017 Jun 8;8(6):e2867. doi: 10.1038/cddis.2017.229.

29.

Midlife Metabolic Profile and the Risk of Late-Life Cognitive Decline.

Tortelli R, Lozupone M, Guerra V, Barulli MR, Imbimbo BP, Capozzo R, Grasso A, Tursi M, Di Dio C, Sardone R, Giannelli G, Seripa D, Misciagna G, Panza F, Logroscino G.

J Alzheimers Dis. 2017;59(1):121-130. doi: 10.3233/JAD-170153.

PMID:
28582862
30.

Non-coding RNAs, the Trojan horse in two-way communication between tumor and stroma in colorectal and hepatocellular carcinoma.

Cătană CS, Pichler M, Giannelli G, Mader RM, Berindan-Neagoe I.

Oncotarget. 2017 Apr 25;8(17):29519-29534. doi: 10.18632/oncotarget.15706. Review.

31.

The TGF-β pathway: a pharmacological target in hepatocellular carcinoma?

Fabregat I, Giannelli G; IT-LIVER Consortium.

Hepat Oncol. 2017 Apr;4(2):35-38. doi: 10.2217/hep-2017-0012. Epub 2017 Jul 6. No abstract available.

32.

Dietary ω-3 Polyunsaturated Fatty Acids Inhibit Tumor Growth in Transgenic ApcMin/+ Mice, Correlating with CB1 Receptor Up-Regulation.

Notarnicola M, Tutino V, De Nunzio V, Dituri F, Caruso MG, Giannelli G.

Int J Mol Sci. 2017 Feb 24;18(3). pii: E485. doi: 10.3390/ijms18030485.

33.

NGS-based transcriptome profiling reveals biomarkers for companion diagnostics of the TGF-β receptor blocker galunisertib in HCC.

Cao Y, Agarwal R, Dituri F, Lupo L, Trerotoli P, Mancarella S, Winter P, Giannelli G.

Cell Death Dis. 2017 Feb 23;8(2):e2634. doi: 10.1038/cddis.2017.44.

34.

Transforming growth factor-β-induced plasticity causes a migratory stemness phenotype in hepatocellular carcinoma.

Malfettone A, Soukupova J, Bertran E, Crosas-Molist E, Lastra R, Fernando J, Koudelkova P, Rani B, Fabra Á, Serrano T, Ramos E, Mikulits W, Giannelli G, Fabregat I.

Cancer Lett. 2017 Apr 28;392:39-50. doi: 10.1016/j.canlet.2017.01.037. Epub 2017 Feb 2.

PMID:
28161507
35.

Treatment of medication-related osteonecrosis of the jaws (MRONJ) with ultrasonic piezoelectric bone surgery. A case series of 20 treated sites.

Blus C, Giannelli G, Szmukler-Moncler S, Orru G.

Oral Maxillofac Surg. 2017 Mar;21(1):41-48. doi: 10.1007/s10006-016-0597-7. Epub 2016 Dec 6.

PMID:
27924427
36.

Hepatic stellate cells induce hepatocellular carcinoma cell resistance to sorafenib through the laminin-332/α3 integrin axis recovery of focal adhesion kinase ubiquitination.

Azzariti A, Mancarella S, Porcelli L, Quatrale AE, Caligiuri A, Lupo L, Dituri F, Giannelli G.

Hepatology. 2016 Dec;64(6):2103-2117. doi: 10.1002/hep.28835. Epub 2016 Oct 27.

PMID:
27639064
37.

Role of epithelial to mesenchymal transition in hepatocellular carcinoma.

Giannelli G, Koudelkova P, Dituri F, Mikulits W.

J Hepatol. 2016 Oct;65(4):798-808. doi: 10.1016/j.jhep.2016.05.007. Epub 2016 May 17. Review.

PMID:
27212245
38.

Fusariosis in a Patient with Acute Myeloid Leukemia: A Case Report and Review of the Literature.

Delia M, Monno R, Giannelli G, Ianora AA, Dalfino L, Pastore D, Capolongo C, Calia C, Tortorano A, Specchia G.

Mycopathologia. 2016 Jun;181(5-6):457-63. doi: 10.1007/s11046-016-9987-5. Epub 2016 Mar 23. Review.

PMID:
27008433
39.

The rationale for targeting TGF-β in chronic liver diseases.

Giannelli G, Mikulits W, Dooley S, Fabregat I, Moustakas A, ten Dijke P, Portincasa P, Winter P, Janssen R, Leporatti S, Herrera B, Sanchez A.

Eur J Clin Invest. 2016 Apr;46(4):349-61. doi: 10.1111/eci.12596. Epub 2016 Mar 12. Review.

PMID:
26823073
40.

TGF-β signalling and liver disease.

Fabregat I, Moreno-Càceres J, Sánchez A, Dooley S, Dewidar B, Giannelli G, Ten Dijke P; IT-LIVER Consortium.

FEBS J. 2016 Jun;283(12):2219-32. doi: 10.1111/febs.13665. Epub 2016 Feb 22. Review.

41.

Laminin-332 sustains chemoresistance and quiescence as part of the human hepatic cancer stem cell niche.

Govaere O, Wouters J, Petz M, Vandewynckel YP, Van den Eynde K, Van den Broeck A, Verhulst S, Dollé L, Gremeaux L, Ceulemans A, Nevens F, van Grunsven LA, Topal B, Vankelecom H, Giannelli G, Van Vlierberghe H, Mikulits W, Komuta M, Roskams T.

J Hepatol. 2016 Mar;64(3):609-17. doi: 10.1016/j.jhep.2015.11.011. Epub 2015 Nov 17.

42.

Double intestinal duplication and incidental neuroendocrine tumor of appendix, a rare case of acute abdomen.

Bellanova G, Valduga P, Costa A, Barbareschi M, De Carli N, Giannelli G, Di Sipio A, Prezzi C, Ciarleglio FA, Beltempo P, Marcucci S, Giacomin D, Depretis G, Brolese A.

Int J Surg Case Rep. 2015;13:116-8. doi: 10.1016/j.ijscr.2015.06.021. Epub 2015 Jul 6.

43.

Neoangiogenesis-related genes are hallmarks of fast-growing hepatocellular carcinomas and worst survival. Results from a prospective study.

Villa E, Critelli R, Lei B, Marzocchi G, Cammà C, Giannelli G, Pontisso P, Cabibbo G, Enea M, Colopi S, Caporali C, Pollicino T, Milosa F, Karampatou A, Todesca P, Bertolini E, Maccio L, Martinez-Chantar ML, Turola E, Del Buono M, De Maria N, Ballestri S, Schepis F, Loria P, Enrico Gerunda G, Losi L, Cillo U.

Gut. 2016 May;65(5):861-9. doi: 10.1136/gutjnl-2014-308483. Epub 2015 Feb 9.

PMID:
25666192
44.

Lysophosphatidic acid receptor LPAR6 supports the tumorigenicity of hepatocellular carcinoma.

Mazzocca A, Dituri F, De Santis F, Filannino A, Lopane C, Betz RC, Li YY, Mukaida N, Winter P, Tortorella C, Giannelli G, Sabbà C.

Cancer Res. 2015 Feb 1;75(3):532-43. doi: 10.1158/0008-5472.CAN-14-1607. Epub 2015 Jan 14.

45.

Circulating TGF-β1-related biomarkers in patients with hepatocellular carcinoma and their association with HCC staging scores.

Dituri F, Serio G, Filannino D, Mascolo A, Sacco R, Villa E, Giannelli G.

Cancer Lett. 2014 Oct 28;353(2):264-71. doi: 10.1016/j.canlet.2014.07.029. Epub 2014 Jul 31.

PMID:
25088578
46.

Moving towards personalised therapy in patients with hepatocellular carcinoma: the role of the microenvironment.

Giannelli G, Rani B, Dituri F, Cao Y, Palasciano G.

Gut. 2014 Oct;63(10):1668-76. doi: 10.1136/gutjnl-2014-307323. Epub 2014 Jul 21. Review.

PMID:
25053718
47.

A mesenchymal-like phenotype and expression of CD44 predict lack of apoptotic response to sorafenib in liver tumor cells.

Fernando J, Malfettone A, Cepeda EB, Vilarrasa-Blasi R, Bertran E, Raimondi G, Fabra À, Alvarez-Barrientos A, Fernández-Salguero P, Fernández-Rodríguez CM, Giannelli G, Sancho P, Fabregat I.

Int J Cancer. 2015 Feb 15;136(4):E161-72. doi: 10.1002/ijc.29097. Epub 2014 Aug 4.

48.

Role of the tissue microenvironment as a therapeutic target in hepatocellular carcinoma.

Rani B, Cao Y, Malfettone A, Tomuleasa C, Fabregat I, Giannelli G.

World J Gastroenterol. 2014 Apr 21;20(15):4128-40. doi: 10.3748/wjg.v20.i15.4128. Review.

49.

Transforming growth factor-β as a therapeutic target in hepatocellular carcinoma.

Giannelli G, Villa E, Lahn M.

Cancer Res. 2014 Apr 1;74(7):1890-4. doi: 10.1158/0008-5472.CAN-14-0243. Epub 2014 Mar 17. Review.

50.

Interplay between cancer cells, macrophages and natural killer cells may actually decide the outcome of therapy with sorafenib.

Tomuleasa C, Giannelli G, Cucuianu A, Aldea M, Paradiso A, Berindan-Neagoe I.

Hepatology. 2014 Jul;60(1):430. doi: 10.1002/hep.26907. Epub 2014 May 27. No abstract available.

PMID:
24338511

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