Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 76


6-Thioguanine and Its Analogs Promote Apoptosis of Castration-Resistant Prostate Cancer Cells in a BRCA2-Dependent Manner.

Laera L, Guaragnella N, Giannattasio S, Moro L.

Cancers (Basel). 2019 Jul 5;11(7). pii: E945. doi: 10.3390/cancers11070945.


Acid Stress Triggers Resistance to Acetic Acid-Induced Regulated Cell Death through Hog1 Activation Which Requires RTG2 in Yeast.

Guaragnella N, Stirpe M, Marzulli D, Mazzoni C, Giannattasio S.

Oxid Med Cell Longev. 2019 Feb 25;2019:4651062. doi: 10.1155/2019/4651062. eCollection 2019.


The phosphodiesterase 5 inhibitor sildenafil decreases the proinflammatory chemokine IL-8 in diabetic cardiomyopathy: in vivo and in vitro evidence.

Giannattasio S, Corinaldesi C, Colletti M, Di Luigi L, Antinozzi C, Filardi T, Scolletta S, Basili S, Lenzi A, Morano S, Crescioli C.

J Endocrinol Invest. 2019 Jun;42(6):715-725. doi: 10.1007/s40618-018-0977-y. Epub 2018 Nov 10.


Editorial: Yeast cell aging and death.

Giannattasio S, Mazzoni C.

FEMS Yeast Res. 2018 Dec 1;18(8). doi: 10.1093/femsyr/foy083. No abstract available.


Mitochondria-cytosol-nucleus crosstalk: learning from Saccharomyces cerevisiae.

Guaragnella N, Coyne LP, Chen XJ, Giannattasio S.

FEMS Yeast Res. 2018 Dec 1;18(8). doi: 10.1093/femsyr/foy088. Review.


Lack of cyclin D3 induces skeletal muscle fiber-type shifting, increased endurance performance and hypermetabolism.

Giannattasio S, Giacovazzo G, Bonato A, Caruso C, Luvisetto S, Coccurello R, Caruso M.

Sci Rep. 2018 Aug 24;8(1):12792. doi: 10.1038/s41598-018-31090-5.


Editorial: Cell Stress, Metabolic Reprogramming, and Cancer.

Giannattasio S, Mirisola MG, Mazzoni C.

Front Oncol. 2018 Jun 25;8:236. doi: 10.3389/fonc.2018.00236. eCollection 2018. No abstract available.


Testosterone-mediated activation of androgenic signalling sustains in vitro the transformed and radioresistant phenotype of rhabdomyosarcoma cell lines.

Giannattasio S, Megiorni F, Di Nisio V, Del Fattore A, Fontanella R, Camero S, Antinozzi C, Festuccia C, Gravina GL, Cecconi S, Dominici C, Di Luigi L, Ciccarelli C, De Cesaris P, Riccioli A, Zani BM, Lenzi A, Pestell RG, Filippini A, Crescioli C, Tombolini V, Marampon F.

J Endocrinol Invest. 2019 Feb;42(2):183-197. doi: 10.1007/s40618-018-0900-6. Epub 2018 May 22.


New perspectives from South-Y-East, not all about death. A report of the 12th lnternational Meeting on Yeast Apoptosis in Bari, Italy, May 14th-18th, 2017.

Guaragnella N, Stirpe M, Burhans W, Côrte-Real M, Gourlay C, Ludovico P, Madeo F, Petranovic D, Winderickx J, Mazzoni C, Giannattasio S.

Microb Cell. 2018 Jan 16;5(2):112-115. doi: 10.15698/mic2018.02.616. No abstract available.


Guidelines and recommendations on yeast cell death nomenclature.

Carmona-Gutierrez D, Bauer MA, Zimmermann A, Aguilera A, Austriaco N, Ayscough K, Balzan R, Bar-Nun S, Barrientos A, Belenky P, Blondel M, Braun RJ, Breitenbach M, Burhans WC, Büttner S, Cavalieri D, Chang M, Cooper KF, Côrte-Real M, Costa V, Cullin C, Dawes I, Dengjel J, Dickman MB, Eisenberg T, Fahrenkrog B, Fasel N, Fröhlich KU, Gargouri A, Giannattasio S, Goffrini P, Gourlay CW, Grant CM, Greenwood MT, Guaragnella N, Heger T, Heinisch J, Herker E, Herrmann JM, Hofer S, Jiménez-Ruiz A, Jungwirth H, Kainz K, Kontoyiannis DP, Ludovico P, Manon S, Martegani E, Mazzoni C, Megeney LA, Meisinger C, Nielsen J, Nyström T, Osiewacz HD, Outeiro TF, Park HO, Pendl T, Petranovic D, Picot S, Polčic P, Powers T, Ramsdale M, Rinnerthaler M, Rockenfeller P, Ruckenstuhl C, Schaffrath R, Segovia M, Severin FF, Sharon A, Sigrist SJ, Sommer-Ruck C, Sousa MJ, Thevelein JM, Thevissen K, Titorenko V, Toledano MB, Tuite M, Vögtle FN, Westermann B, Winderickx J, Wissing S, Wölfl S, Zhang ZJ, Zhao RY, Zhou B, Galluzzi L, Kroemer G, Madeo F.

Microb Cell. 2018 Jan 1;5(1):4-31. doi: 10.15698/mic2018.01.607. Review.


Mitochondrial Dysfunction: A Novel Potential Driver of Epithelial-to-Mesenchymal Transition in Cancer.

Guerra F, Guaragnella N, Arbini AA, Bucci C, Giannattasio S, Moro L.

Front Oncol. 2017 Dec 1;7:295. doi: 10.3389/fonc.2017.00295. eCollection 2017. Review.


SLC25A10 biallelic mutations in intractable epileptic encephalopathy with complex I deficiency.

Punzi G, Porcelli V, Ruggiu M, Hossain MF, Menga A, Scarcia P, Castegna A, Gorgoglione R, Pierri CL, Laera L, Lasorsa FM, Paradies E, Pisano I, Marobbio CMT, Lamantea E, Ghezzi D, Tiranti V, Giannattasio S, Donati MA, Guerrini R, Palmieri L, Palmieri F, De Grassi A.

Hum Mol Genet. 2018 Feb 1;27(3):499-504. doi: 10.1093/hmg/ddx419.


The transcription factors ADR1 or CAT8 are required for RTG pathway activation and evasion from yeast acetic acid-induced programmed cell death in raffinose.

Laera L, Guaragnella N, Ždralević M, Marzulli D, Liu Z, Giannattasio S.

Microb Cell. 2016 Dec 2;3(12):621-631. doi: 10.15698/mic2016.12.549.


Heterologous expression of carnation Italian ringspot virus p36 protein enhances necrotic cell death in response to acetic acid in Saccharomyces cerevisiae.

Rubino L, Guaragnella N, Giannattasio S.

Mech Ageing Dev. 2017 Jan;161(Pt B):255-261. doi: 10.1016/j.mad.2016.09.004. Epub 2016 Sep 13.


Silencing of BRCA2 to Identify Novel BRCA2-regulated Biological Functions in Cultured Human Cells.

Moro L, Guaragnella N, Giannattasio S.

J Vis Exp. 2015 Aug 12;(102):e52849. doi: 10.3791/52849.


Proteome and metabolome profiling of wild-type and YCA1-knock-out yeast cells during acetic acid-induced programmed cell death.

Longo V, Ždralević M, Guaragnella N, Giannattasio S, Zolla L, Timperio AM.

J Proteomics. 2015 Oct 14;128:173-88. doi: 10.1016/j.jprot.2015.08.003. Epub 2015 Aug 9.


Differential proteome-metabolome profiling of YCA1-knock-out and wild type cells reveals novel metabolic pathways and cellular processes dependent on the yeast metacaspase.

Ždralević M, Longo V, Guaragnella N, Giannattasio S, Timperio AM, Zolla L.

Mol Biosyst. 2015 Jun;11(6):1573-83. doi: 10.1039/c4mb00660g.


Yeast as a tool to study mitochondrial retrograde pathway en route to cell stress response.

Ždralević M, Guaragnella N, Giannattasio S.

Methods Mol Biol. 2015;1265:321-31. doi: 10.1007/978-1-4939-2288-8_22.


Mitochondrial dysfunction in cancer chemoresistance.

Guaragnella N, Giannattasio S, Moro L.

Biochem Pharmacol. 2014 Nov 1;92(1):62-72. doi: 10.1016/j.bcp.2014.07.027. Epub 2014 Aug 12. Review.


Silencing of BRCA2 decreases anoikis and its heterologous expression sensitizes yeast cells to acetic acid-induced programmed cell death.

Guaragnella N, Marra E, Galli A, Moro L, Giannattasio S.

Apoptosis. 2014 Sep;19(9):1330-41. doi: 10.1007/s10495-014-1006-z.


Yeast stress, aging, and death.

Mazzoni C, Giannattasio S, Winderickx J, Ludovico P.

Oxid Med Cell Longev. 2013;2013:684395. doi: 10.1155/2013/684395. Epub 2013 Dec 2. No abstract available.


The expanding role of yeast in cancer research and diagnosis: insights into the function of the oncosuppressors p53 and BRCA1/2.

Guaragnella N, Palermo V, Galli A, Moro L, Mazzoni C, Giannattasio S.

FEMS Yeast Res. 2014 Feb;14(1):2-16. doi: 10.1111/1567-1364.12094. Epub 2013 Oct 30. Review.


Yeast growth in raffinose results in resistance to acetic-acid induced programmed cell death mostly due to the activation of the mitochondrial retrograde pathway.

Guaragnella N, Ždralević M, Lattanzio P, Marzulli D, Pracheil T, Liu Z, Passarella S, Marra E, Giannattasio S.

Biochim Biophys Acta. 2013 Dec;1833(12):2765-2774. doi: 10.1016/j.bbamcr.2013.07.017. Epub 2013 Jul 29.


Yeast between life and death: a summary of the Ninth International Meeting on Yeast Apoptosis in Rome, Italy, 17-20 September 2012.

Guaragnella N, Palermo V, Burhans WC, Gourlay CW, Ludovico P, Madeo F, Giannattasio S, Mazzoni C.

Cell Death Differ. 2013 Sep;20(9):1281-3. doi: 10.1038/cdd.2013.71. Epub 2013 Jun 28. No abstract available.


Molecular mechanisms of Saccharomyces cerevisiae stress adaptation and programmed cell death in response to acetic acid.

Giannattasio S, Guaragnella N, Zdralević M, Marra E.

Front Microbiol. 2013 Feb 20;4:33. doi: 10.3389/fmicb.2013.00033. eCollection 2013.


Stress-related mitochondrial components and mitochondrial genome as targets of anticancer therapy.

Giannattasio S, Guaragnella N, Arbini AA, Moro L.

Chem Biol Drug Des. 2013 Jan;81(1):102-12. doi: 10.1111/cbdd.12057. Review.


The N-acetylcysteine-insensitive acetic acid-induced yeast programmed cell death occurs without macroautophagy.

Antonacci L, Guaragnella N, Ždralevic M, Passarella S, Marra E, Giannattasio S.

Curr Pharm Biotechnol. 2012 Dec;13(15):2705-11.


The role of mitochondria in yeast programmed cell death.

Guaragnella N, Zdralević M, Antonacci L, Passarella S, Marra E, Giannattasio S.

Front Oncol. 2012 Jul 3;2:70. doi: 10.3389/fonc.2012.00070. eCollection 2012.


Yeast as a tool to study signaling pathways in mitochondrial stress response and cytoprotection.

Zdralević M, Guaragnella N, Antonacci L, Marra E, Giannattasio S.

ScientificWorldJournal. 2012;2012:912147. doi: 10.1100/2012/912147. Epub 2012 Feb 2. Review.


Achievements and perspectives in yeast acetic acid-induced programmed cell death pathways.

Guaragnella N, Antonacci L, Passarella S, Marra E, Giannattasio S.

Biochem Soc Trans. 2011 Oct;39(5):1538-43. doi: 10.1042/BST0391538. Review.


Cytochrome c Trp65Ser substitution results in inhibition of acetic acid-induced programmed cell death in Saccharomyces cerevisiae.

Guaragnella N, Passarella S, Marra E, Giannattasio S.

Mitochondrion. 2011 Nov;11(6):987-91. doi: 10.1016/j.mito.2011.08.007. Epub 2011 Sep 2.


Knock-out of metacaspase and/or cytochrome c results in the activation of a ROS-independent acetic acid-induced programmed cell death pathway in yeast.

Guaragnella N, Passarella S, Marra E, Giannattasio S.

FEBS Lett. 2010 Aug 20;584(16):3655-60. doi: 10.1016/j.febslet.2010.07.044. Epub 2010 Aug 3.


Yeast acetic acid-induced programmed cell death can occur without cytochrome c release which requires metacaspase YCA1.

Guaragnella N, Bobba A, Passarella S, Marra E, Giannattasio S.

FEBS Lett. 2010 Jan 4;584(1):224-8. doi: 10.1016/j.febslet.2009.11.072.


Molecular evolution of B6 enzymes: binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme.

Vacca RA, Giannattasio S, Capitani G, Marra E, Christen P.

BMC Biochem. 2008 Jun 19;9:17. doi: 10.1186/1471-2091-9-17.


Pleiotropic effects of the yeast Sal1 and Aac2 carriers on mitochondrial function via an activity distinct from adenine nucleotide transport.

Kucejova B, Li L, Wang X, Giannattasio S, Chen XJ.

Mol Genet Genomics. 2008 Jul;280(1):25-39. doi: 10.1007/s00438-008-0342-5. Epub 2008 Apr 23.


Cytochrome c is released from coupled mitochondria of yeast en route to acetic acid-induced programmed cell death and can work as an electron donor and a ROS scavenger.

Giannattasio S, Atlante A, Antonacci L, Guaragnella N, Lattanzio P, Passarella S, Marra E.

FEBS Lett. 2008 Apr 30;582(10):1519-25. doi: 10.1016/j.febslet.2008.03.048. Epub 2008 Apr 7.


A transient proteasome activation is needed for acetic acid-induced programmed cell death to occur in Saccharomyces cerevisiae.

Valenti D, Vacca RA, Guaragnella N, Passarella S, Marra E, Giannattasio S.

FEMS Yeast Res. 2008 May;8(3):400-4. doi: 10.1111/j.1567-1364.2008.00348.x. Epub 2008 Jan 19.


Catalase T and Cu,Zn-superoxide dismutase in the acetic acid-induced programmed cell death in Saccharomyces cerevisiae.

Guaragnella N, Antonacci L, Giannattasio S, Marra E, Passarella S.

FEBS Lett. 2008 Jan 23;582(2):210-4. Epub 2007 Dec 17.


Hydrogen peroxide and superoxide anion production during acetic acid-induced yeast programmed cell death.

Guaragnella N, Antonacci L, Passarella S, Marra E, Giannattasio S.

Folia Microbiol (Praha). 2007;52(3):237-40.


YCA1 participates in the acetic acid induced yeast programmed cell death also in a manner unrelated to its caspase-like activity.

Guaragnella N, Pereira C, Sousa MJ, Antonacci L, Passarella S, Côrte-Real M, Marra E, Giannattasio S.

FEBS Lett. 2006 Dec 22;580(30):6880-4. Epub 2006 Nov 29.


Molecular basis of cystic fibrosis in Lithuania: incomplete CFTR mutation detection by PCR-based screening protocols.

Giannattasio S, Bobba A, Jurgelevicius V, Vacca RA, Lattanzio P, Merafina RS, Utkus A, Kucinskas V, Marra E.

Genet Test. 2006 Fall;10(3):169-73.


Retrograde response to mitochondrial dysfunction is separable from TOR1/2 regulation of retrograde gene expression.

Giannattasio S, Liu Z, Thornton J, Butow RA.

J Biol Chem. 2005 Dec 30;280(52):42528-35. Epub 2005 Oct 27.


An increase in the ATP levels occurs in cerebellar granule cells en route to apoptosis in which ATP derives from both oxidative phosphorylation and anaerobic glycolysis.

Atlante A, Giannattasio S, Bobba A, Gagliardi S, Petragallo V, Calissano P, Marra E, Passarella S.

Biochim Biophys Acta. 2005 Jun 1;1708(1):50-62. Epub 2005 Feb 7.


Acid stress adaptation protects Saccharomyces cerevisiae from acetic acid-induced programmed cell death.

Giannattasio S, Guaragnella N, Corte-Real M, Passarella S, Marra E.

Gene. 2005 Jul 18;354:93-8.


Non-radioactive detection of five common microsatellite markers for ATP7B gene in Wilson disease patients.

Bobba A, Marra E, Fathallah DM, Giannattasio S.

Mol Cell Probes. 2003 Dec;17(6):271-4.


The molecular basis of phenylketonuria in Latvia.

Pronina N, Giannattasio S, Lattanzio P, Lugovska R, Vevere P, Kornejeva A.

Hum Mutat. 2003 Apr;21(4):398-9.


The molecular basis of phenylketonuria in Lithuania.

Kasnauskiene J, Giannattasio S, Lattanzio P, Cimbalistiene L, Kucinskas V.

Hum Mutat. 2003 Apr;21(4):398.


Genetic heterogeneity in five Italian regions: analysis of PAH mutations and minihaplotypes.

Giannattasio S, Dianzani I, Lattanzio P, Spada M, Romano V, Calì F, Andria G, Ponzone A, Marra E, Piazza A.

Hum Hered. 2001;52(3):154-9.


Glutamate neurotoxicity, oxidative stress and mitochondria.

Atlante A, Calissano P, Bobba A, Giannattasio S, Marra E, Passarella S.

FEBS Lett. 2001 May 18;497(1):1-5. Review.

Supplemental Content

Loading ...
Support Center