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Long-term sequential deferiprone and deferasirox therapy in transfusion-dependent thalassaemia patients: a prospective clinical trial.

Vitrano A, Ruffo GB, Pepe A, D'Ascola DG, Caruso V, Filosa A, Masera N, Pitrolo L, Rigano P, Cuccia L, Giangreco A, Di Maggio R, Maggio A.

Br J Haematol. 2019 Sep;186(6):e209-e211. doi: 10.1111/bjh.16101. Epub 2019 Jul 25. No abstract available.


How breathing can help you make better decisions: Two studies on the effects of breathing patterns on heart rate variability and decision-making in business cases.

De Couck M, Caers R, Musch L, Fliegauf J, Giangreco A, Gidron Y.

Int J Psychophysiol. 2019 May;139:1-9. doi: 10.1016/j.ijpsycho.2019.02.011. Epub 2019 Mar 1.


Cross-talk between human airway epithelial cells and 3T3-J2 feeder cells involves partial activation of human MET by murine HGF.

Hynds RE, Gowers KHC, Nigro E, Butler CR, Bonfanti P, Giangreco A, Prêle CM, Janes SM.

PLoS One. 2018 May 17;13(5):e0197129. doi: 10.1371/journal.pone.0197129. eCollection 2018.


Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids.

Nikolić MZ, Caritg O, Jeng Q, Johnson JA, Sun D, Howell KJ, Brady JL, Laresgoiti U, Allen G, Butler R, Zilbauer M, Giangreco A, Rawlins EL.

Elife. 2017 Jun 30;6. pii: e26575. doi: 10.7554/eLife.26575.


Mechanistic overlap between chronic lung injury and cancer: ERS Lung Science Conference 2017 report.

Gosens R, Giangreco A, Sahai E, Chambers RC.

Eur Respir Rev. 2017 Jun 28;26(144). pii: 170060. doi: 10.1183/16000617.0060-2017. Print 2017 Jun 30. No abstract available.


Epithelial cell migration as a potential therapeutic target in early lung cancer.

Millar FR, Janes SM, Giangreco A.

Eur Respir Rev. 2017 Jan 31;26(143). pii: 160069. doi: 10.1183/16000617.0069-2016. Print 2017 Jan. Review.


microRNAs and DICER1 are regulated by 1,25-dihydroxyvitamin D in prostate stroma.

Dambal S, Giangreco AA, Acosta AM, Fairchild A, Richards Z, Deaton R, Wagner D, Vieth R, Gann PH, Kajdacsy-Balla A, Van der Kwast T, Nonn L.

J Steroid Biochem Mol Biol. 2017 Mar;167:192-202. doi: 10.1016/j.jsbmb.2017.01.004. Epub 2017 Jan 12.


Expansion of Human Airway Basal Stem Cells and Their Differentiation as 3D Tracheospheres.

Hynds RE, Butler CR, Janes SM, Giangreco A.

Methods Mol Biol. 2019;1576:43-53. doi: 10.1007/7651_2016_5.


CADM1 inhibits squamous cell carcinoma progression by reducing STAT3 activity.

Vallath S, Sage EK, Kolluri KK, Lourenco SN, Teixeira VS, Chimalapati S, George PJ, Janes SM, Giangreco A.

Sci Rep. 2016 Apr 1;6:24006. doi: 10.1038/srep24006.


Rapid Expansion of Human Epithelial Stem Cells Suitable for Airway Tissue Engineering.

Butler CR, Hynds RE, Gowers KH, Lee Ddo H, Brown JM, Crowley C, Teixeira VH, Smith CM, Urbani L, Hamilton NJ, Thakrar RM, Booth HL, Birchall MA, De Coppi P, Giangreco A, O'Callaghan C, Janes SM.

Am J Respir Crit Care Med. 2016 Jul 15;194(2):156-68. doi: 10.1164/rccm.201507-1414OC.


Real-life experience with liver iron concentration R2 MRI measurement in patients with hemoglobinopathies: baseline data from LICNET.

Vitrano A, Calvaruso G, Tesé L, Gioia F, Cassarà F, Campisi S, Butera F, Commendatore V, Rizzo M, Santoro V, Cigna V, Quota A, Bagnato S, Argento C, Fidone C, Schembari D, Gerardi C, Barbiera F, Bellisssima G, Giugno G, Polizzi G, Rosso R, Abbate G, Caruso V, Chiodi E, Gamberini MR, Giorgi B, Putti MC, Filosa A, De Ritis MR, Oliva E, Arcadi N, Fustaneo M, Mistretta L, Di Maggio R, Sacco M, Veronica DS, Giangreco A, Maggio A.

Eur J Haematol. 2016 Oct;97(4):361-70. doi: 10.1111/ejh.12740. Epub 2016 Feb 23.


An official American Thoracic Society workshop report: stem cells and cell therapies in lung biology and diseases.

Weiss DJ, Chambers D, Giangreco A, Keating A, Kotton D, Lelkes PI, Wagner DE, Prockop DJ; ATS Subcommittee on Stem Cells and Cell Therapies.

Ann Am Thorac Soc. 2015 Apr;12(4):S79-97. doi: 10.1513/AnnalsATS.201502-086ST.


Differential expression and regulation of vitamin D hydroxylases and inflammatory genes in prostate stroma and epithelium by 1,25-dihydroxyvitamin D in men with prostate cancer and an in vitro model.

Giangreco AA, Dambal S, Wagner D, Van der Kwast T, Vieth R, Prins GS, Nonn L.

J Steroid Biochem Mol Biol. 2015 Apr;148:156-65. doi: 10.1016/j.jsbmb.2014.10.004. Epub 2014 Oct 8.


The best laid schemes of airway repair.

Rawlins EL, Giangreco A.

Eur Respir J. 2014 Aug;44(2):299-301. doi: 10.1183/09031936.00088014. No abstract available.


Coupled cellular therapy and magnetic targeting for airway regeneration.

Ordidge KL, Gregori M, Kalber TL, Lythgoe MF, Janes SM, Giangreco A.

Biochem Soc Trans. 2014 Jun;42(3):657-61. doi: 10.1042/BST20140089.


The biochemical determinants of tissue regeneration.

Giangreco A, Merry CL.

Biochem Soc Trans. 2014 Jun;42(3):607-8. doi: 10.1042/BST20140095.


Systemic but not topical TRAIL-expressing mesenchymal stem cells reduce tumour growth in malignant mesothelioma.

Sage EK, Kolluri KK, McNulty K, Lourenco Sda S, Kalber TL, Ordidge KL, Davies D, Gary Lee YC, Giangreco A, Janes SM.

Thorax. 2014 Jul;69(7):638-47. doi: 10.1136/thoraxjnl-2013-204110. Epub 2014 Feb 24.


Cell migration leads to spatially distinct but clonally related airway cancer precursors.

Pipinikas CP, Kiropoulos TS, Teixeira VH, Brown JM, Varanou A, Falzon M, Capitanio A, Bottoms SE, Carroll B, Navani N, McCaughan F, George JP, Giangreco A, Wright NA, McDonald SA, Graham TA, Janes SM.

Thorax. 2014 Jun;69(6):548-57. doi: 10.1136/thoraxjnl-2013-204198. Epub 2014 Feb 18.


Targeting EGFR signalling in chronic lung disease: therapeutic challenges and opportunities.

Vallath S, Hynds RE, Succony L, Janes SM, Giangreco A.

Eur Respir J. 2014 Aug;44(2):513-22. doi: 10.1183/09031936.00146413. Epub 2014 Jan 16. Review.


Stochastic homeostasis in human airway epithelium is achieved by neutral competition of basal cell progenitors.

Teixeira VH, Nadarajan P, Graham TA, Pipinikas CP, Brown JM, Falzon M, Nye E, Poulsom R, Lawrence D, Wright NA, McDonald S, Giangreco A, Simons BD, Janes SM.

Elife. 2013 Oct 22;2:e00966. doi: 10.7554/eLife.00966.


Tumor suppressor microRNAs, miR-100 and -125b, are regulated by 1,25-dihydroxyvitamin D in primary prostate cells and in patient tissue.

Giangreco AA, Vaishnav A, Wagner D, Finelli A, Fleshner N, Van der Kwast T, Vieth R, Nonn L.

Cancer Prev Res (Phila). 2013 May;6(5):483-94. doi: 10.1158/1940-6207.CAPR-12-0253. Epub 2013 Mar 15.


Randomized clinical trial of vitamin D3 doses on prostatic vitamin D metabolite levels and ki67 labeling in prostate cancer patients.

Wagner D, Trudel D, Van der Kwast T, Nonn L, Giangreco AA, Li D, Dias A, Cardoza M, Laszlo S, Hersey K, Klotz L, Finelli A, Fleshner N, Vieth R.

J Clin Endocrinol Metab. 2013 Apr;98(4):1498-507. doi: 10.1210/jc.2012-4019. Epub 2013 Mar 5.


The sum of many small changes: microRNAs are specifically and potentially globally altered by vitamin D3 metabolites.

Giangreco AA, Nonn L.

J Steroid Biochem Mol Biol. 2013 Jul;136:86-93. doi: 10.1016/j.jsbmb.2013.01.001. Epub 2013 Jan 16. Review.


LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development.

Lu L, Teixeira VH, Yuan Z, Graham TA, Endesfelder D, Kolluri K, Al-Juffali N, Hamilton N, Nicholson AG, Falzon M, Kschischo M, Swanton C, Wright NA, Carroll B, Watt FM, George JP, Jensen KB, Giangreco A, Janes SM.

J Pathol. 2013 Mar;229(4):608-20. doi: 10.1002/path.4148.


Concise review: the relevance of human stem cell-derived organoid models for epithelial translational medicine.

Hynds RE, Giangreco A.

Stem Cells. 2013 Mar;31(3):417-22. doi: 10.1002/stem.1290. Review.


Murine aggregation chimeras and wholemount imaging in airway stem cell biology.

Rosewell IR, Giangreco A.

Methods Mol Biol. 2012;916:263-74. doi: 10.1007/978-1-61779-980-8_20.


Interventional and intrinsic airway homeostasis and repair.

Butler C, Birchall M, Giangreco A.

Physiology (Bethesda). 2012 Jun;27(3):140-7. doi: 10.1152/physiol.00001.2012. Review.


Epidermal Cadm1 expression promotes autoimmune alopecia via enhanced T cell adhesion and cytotoxicity.

Giangreco A, Hoste E, Takai Y, Rosewell I, Watt FM.

J Immunol. 2012 Feb 1;188(3):1514-22. doi: 10.4049/jimmunol.1003342. Epub 2011 Dec 30.


β-Catenin determines upper airway progenitor cell fate and preinvasive squamous lung cancer progression by modulating epithelial-mesenchymal transition.

Giangreco A, Lu L, Vickers C, Teixeira VH, Groot KR, Butler CR, Ilieva EV, George PJ, Nicholson AG, Sage EK, Watt FM, Janes SM.

J Pathol. 2012 Mar;226(4):575-87. doi: 10.1002/path.3962. Epub 2012 Jan 17. Erratum in: J Pathol. 2019 Sep;249(1):137.


miR-183-96-182 cluster is overexpressed in prostate tissue and regulates zinc homeostasis in prostate cells.

Mihelich BL, Khramtsova EA, Arva N, Vaishnav A, Johnson DN, Giangreco AA, Martens-Uzunova E, Bagasra O, Kajdacsy-Balla A, Nonn L.

J Biol Chem. 2011 Dec 30;286(52):44503-11. doi: 10.1074/jbc.M111.262915. Epub 2011 Nov 1.


Myd88 deficiency influences murine tracheal epithelial metaplasia and submucosal gland abundance.

Giangreco A, Lu L, Mazzatti DJ, Spencer-Dene B, Nye E, Teixeira VH, Janes SM.

J Pathol. 2011 Jun;224(2):190-202. doi: 10.1002/path.2876.


The relationship between stress, hemispheric preference and decision making among managers.

Gidron Y, Giangreco A, Vanuxem C, Leboucher O.

Anxiety Stress Coping. 2012 Mar;25(2):219-28. doi: 10.1080/10615806.2011.571769. Epub 2011 Jun 1.


War outside, ceasefire inside: An analysis of the performance appraisal system of a public hospital in a zone of conflict.

Giangreco A, Carugati A, Sebastiano A, Tamimi HA.

Eval Program Plann. 2012 Feb;35(1):161-70. doi: 10.1016/j.evalprogplan.2010.11.004. Epub 2010 Nov 10. Review.


Hepatocellular carcinoma in patients with thalassaemia syndromes: clinical characteristics and outcome in a long term single centre experience.

Restivo Pantalone G, Renda D, Valenza F, D'Amato F, Vitrano A, Cassarà F, Rigano P, Di Salvo V, Giangreco A, Bevacqua E, Maggio A.

Br J Haematol. 2010 Jul;150(2):245-7. doi: 10.1111/j.1365-2141.2010.08180.x. Epub 2010 Apr 28. No abstract available.


Necl2 regulates epidermal adhesion and wound repair.

Giangreco A, Jensen KB, Takai Y, Miyoshi J, Watt FM.

Development. 2009 Oct;136(20):3505-14. doi: 10.1242/dev.038232.


Human skin aging is associated with reduced expression of the stem cell markers beta1 integrin and MCSP.

Giangreco A, Goldie SJ, Failla V, Saintigny G, Watt FM.

J Invest Dermatol. 2010 Feb;130(2):604-8. doi: 10.1038/jid.2009.297. Epub 2009 Sep 24. No abstract available.


Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis.

Driskell RR, Giangreco A, Jensen KB, Mulder KW, Watt FM.

Development. 2009 Aug;136(16):2815-23. doi: 10.1242/dev.038620. Epub 2009 Jul 15.


Stem cells are dispensable for lung homeostasis but restore airways after injury.

Giangreco A, Arwert EN, Rosewell IR, Snyder J, Watt FM, Stripp BR.

Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9286-91. doi: 10.1073/pnas.0900668106. Epub 2009 May 28.


beta-Catenin is not necessary for maintenance or repair of the bronchiolar epithelium.

Zemke AC, Teisanu RM, Giangreco A, Drake JA, Brockway BL, Reynolds SD, Stripp BR.

Am J Respir Cell Mol Biol. 2009 Nov;41(5):535-43. doi: 10.1165/rcmb.2008-0407OC. Epub 2009 Feb 12.


Conditional stabilization of beta-catenin expands the pool of lung stem cells.

Reynolds SD, Zemke AC, Giangreco A, Brockway BL, Teisanu RM, Drake JA, Mariani T, Di PY, Taketo MM, Stripp BR.

Stem Cells. 2008 May;26(5):1337-46. doi: 10.1634/stemcells.2008-0053. Epub 2008 Mar 20.


Epidermal stem cells are retained in vivo throughout skin aging.

Giangreco A, Qin M, Pintar JE, Watt FM.

Aging Cell. 2008 Mar;7(2):250-9. doi: 10.1111/j.1474-9726.2008.00372.x. Epub 2008 Jan 21.


Squamous cell cancers contain a side population of stem-like cells that are made chemosensitive by ABC transporter blockade.

Loebinger MR, Giangreco A, Groot KR, Prichard L, Allen K, Simpson C, Bazley L, Navani N, Tibrewal S, Davies D, Janes SM.

Br J Cancer. 2008 Jan 29;98(2):380-7. doi: 10.1038/sj.bjc.6604185. Epub 2008 Jan 22.


Lung cancer and lung stem cells: strange bedfellows?

Giangreco A, Groot KR, Janes SM.

Am J Respir Crit Care Med. 2007 Mar 15;175(6):547-53. Epub 2006 Dec 7. Review.


The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells.

Nijhof JG, Braun KM, Giangreco A, van Pelt C, Kawamoto H, Boyd RL, Willemze R, Mullenders LH, Watt FM, de Gruijl FR, van Ewijk W.

Development. 2006 Aug;133(15):3027-37. Epub 2006 Jul 3.


Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells.

Silva-Vargas V, Lo Celso C, Giangreco A, Ofstad T, Prowse DM, Braun KM, Watt FM.

Dev Cell. 2005 Jul;9(1):121-31.


Airway injury in lung disease pathophysiology: selective depletion of airway stem and progenitor cell pools potentiates lung inflammation and alveolar dysfunction.

Reynolds SD, Giangreco A, Hong KU, McGrath KE, Ortiz LA, Stripp BR.

Am J Physiol Lung Cell Mol Physiol. 2004 Dec;287(6):L1256-65. Epub 2004 Aug 6.


Molecular phenotype of airway side population cells.

Giangreco A, Shen H, Reynolds SD, Stripp BR.

Am J Physiol Lung Cell Mol Physiol. 2004 Apr;286(4):L624-30. Epub 2003 Aug 8.


Ethanol stimulates apolipoprotein B mRNA editing in the absence of de novo RNA or protein synthesis.

Giangreco A, Sowden MP, Mikityansky I, Smith HC.

Biochem Biophys Res Commun. 2001 Dec 21;289(5):1162-7.


Mercapturic acids (N-acetylcysteine S-conjugates) as endogenous substrates for the renal organic anion transporter-1.

Pombrio JM, Giangreco A, Li L, Wempe MF, Anders MW, Sweet DH, Pritchard JB, Ballatori N.

Mol Pharmacol. 2001 Nov;60(5):1091-9.


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