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Items: 1 to 50 of 59

1.

HLA-DQA1 and HLA-DQB1 Alleles, Conferring Susceptibility to Celiac Disease and Type 1 Diabetes, are More Expressed Than Non-Predisposing Alleles and are Coordinately Regulated.

Farina F, Picascia S, Pisapia L, Barba P, Vitale S, Franzese A, Mozzillo E, Gianfrani C, Del Pozzo G G.

Cells. 2019 Jul 19;8(7). pii: E751. doi: 10.3390/cells8070751.

2.

The HLA-DRB1 risk alleles for multiple sclerosis are differentially expressed in blood cells of patients from Southern Italy.

Pisapia L, Cerillo I, Farina F, Zimbardo A, Barba P, Orefice G, Gianfrani C, Strazzullo M, Del Pozzo G.

Int J Immunogenet. 2019 Jul 17. doi: 10.1111/iji.12450. [Epub ahead of print]

PMID:
31313885
3.

In Situ Gluten-Chitosan Interlocked Self-Assembled Supramolecular Architecture Reduces T-Cell-Mediated Immune Response to Gluten in Celiac Disease.

Ribeiro M, Picascia S, Rhazi L, Gianfrani C, Carrillo JM, Rodriguez-Quijano M, Branlard G, Nunes FM.

Mol Nutr Food Res. 2018 Dec;62(23):e1800646. doi: 10.1002/mnfr.201800646. Epub 2018 Oct 21.

PMID:
30289620
4.

Vaccine Immunotherapy for Celiac Disease.

Di Sabatino A, Lenti MV, Corazza GR, Gianfrani C.

Front Med (Lausanne). 2018 Jun 26;5:187. doi: 10.3389/fmed.2018.00187. eCollection 2018.

5.

Expression level of risk genes of MHC class II is a susceptibility factor for autoimmunity: New insights.

Gianfrani C, Pisapia L, Picascia S, Strazzullo M, Del Pozzo G.

J Autoimmun. 2018 May;89:1-10. doi: 10.1016/j.jaut.2017.12.016. Epub 2018 Jan 10. Review.

PMID:
29331322
6.

Presymptomatic Diagnosis of Celiac Disease in Predisposed Children: The Role of Gene Expression Profile.

Galatola M, Cielo D, Panico C, Stellato P, Malamisura B, Carbone L, Gianfrani C, Troncone R, Greco L, Auricchio R.

J Pediatr Gastroenterol Nutr. 2017 Sep;65(3):314-320. doi: 10.1097/MPG.0000000000001519.

PMID:
28827480
7.

Cytokine production profile in intestinal mucosa of paediatric inflammatory bowel disease.

Vitale S, Strisciuglio C, Pisapia L, Miele E, Barba P, Vitale A, Cenni S, Bassi V, Maglio M, Del Pozzo G, Troncone R, Staiano A, Gianfrani C.

PLoS One. 2017 Aug 10;12(8):e0182313. doi: 10.1371/journal.pone.0182313. eCollection 2017.

8.

Lack of immunogenicity of hydrolysed wheat flour in patients with coeliac disease after a short-term oral challenge.

Mandile R, Picascia S, Parrella C, Camarca A, Gobbetti M, Greco L, Troncone R, Gianfrani C, Auricchio R.

Aliment Pharmacol Ther. 2017 Aug;46(4):440-446. doi: 10.1111/apt.14175. Epub 2017 Jun 19.

9.

Gliadin-reactive T cells in Italian children from preventCD cohort at high risk of celiac disease.

Camarca A, Auricchio R, Picascia S, Fierro O, Maglio M, Miele E, Malamisura B, Greco L, Troncone R, Gianfrani C.

Pediatr Allergy Immunol. 2017 Jun;28(4):362-369. doi: 10.1111/pai.12720.

PMID:
28339124
10.

Gliadin-Specific CD8+ T Cell Responses Restricted by HLA Class I A*0101 and B*0801 Molecules in Celiac Disease Patients.

Picascia S, Sidney J, Camarca A, Mazzarella G, Giardullo N, Greco L, Auricchio R, Auricchio S, Troncone R, Sette A, Gianfrani C.

J Immunol. 2017 Mar 1;198(5):1838-1845. doi: 10.4049/jimmunol.1601208. Epub 2017 Feb 1.

11.

Microwave-based treatments of wheat kernels do not abolish gluten epitopes implicated in celiac disease.

Gianfrani C, Mamone G, la Gatta B, Camarca A, Di Stasio L, Maurano F, Picascia S, Capozzi V, Perna G, Picariello G, Di Luccia A.

Food Chem Toxicol. 2017 Mar;101:105-113. doi: 10.1016/j.fct.2017.01.010. Epub 2017 Jan 12.

PMID:
28088490
12.

Human Peripheral Blood Mononuclear Cell Function and Dendritic Cell Differentiation Are Affected by Bisphenol-A Exposure.

Camarca A, Gianfrani C, Ariemma F, Cimmino I, Bruzzese D, Scerbo R, Picascia S, D'Esposito V, Beguinot F, Formisano P, Valentino R.

PLoS One. 2016 Aug 10;11(8):e0161122. doi: 10.1371/journal.pone.0161122. eCollection 2016.

13.

The cross-talk between enterocytes and intraepithelial lymphocytes.

Vitale S, Picascia S, Gianfrani C.

Mol Cell Pediatr. 2016 Dec;3(1):20. doi: 10.1186/s40348-016-0048-4. Epub 2016 Jun 1. Review.

14.

HLA-DQ2.5 genes associated with celiac disease risk are preferentially expressed with respect to non-predisposing HLA genes: Implication for anti-gluten T cell response.

Pisapia L, Camarca A, Picascia S, Bassi V, Barba P, Del Pozzo G, Gianfrani C.

J Autoimmun. 2016 Jun;70:63-72. doi: 10.1016/j.jaut.2016.03.016. Epub 2016 Apr 12.

PMID:
27083396
15.

In the Intestinal Mucosa of Children With Potential Celiac Disease IL-21 and IL-17A are Less Expressed than in the Active Disease.

Borrelli M, Gianfrani C, Lania G, Aitoro R, Ferrara K, Nanayakkara M, Ponticelli D, Zanzi D, Discepolo V, Vitale S, Barone MV, Troncone R, Auricchio R, Maglio M.

Am J Gastroenterol. 2016 Jan;111(1):134-44. doi: 10.1038/ajg.2015.390. Epub 2016 Jan 12.

PMID:
26753888
16.

Gliadin-Specific T-Cells Mobilized in the Peripheral Blood of Coeliac Patients by Short Oral Gluten Challenge: Clinical Applications.

Picascia S, Mandile R, Auricchio R, Troncone R, Gianfrani C.

Nutrients. 2015 Dec 2;7(12):10020-31. doi: 10.3390/nu7125515. Review.

17.

Engineering of Kuma030: A Gliadin Peptidase That Rapidly Degrades Immunogenic Gliadin Peptides in Gastric Conditions.

Wolf C, Siegel JB, Tinberg C, Camarca A, Gianfrani C, Paski S, Guan R, Montelione G, Baker D, Pultz IS.

J Am Chem Soc. 2015 Oct 14;137(40):13106-13. doi: 10.1021/jacs.5b08325. Epub 2015 Sep 29.

18.

Consistency in polyclonal T-cell responses to gluten between children and adults with celiac disease.

Hardy MY, Girardin A, Pizzey C, Cameron DJ, Watson KA, Picascia S, Auricchio R, Greco L, Gianfrani C, La Gruta NL, Anderson RP, Tye-Din JA.

Gastroenterology. 2015 Nov;149(6):1541-1552.e2. doi: 10.1053/j.gastro.2015.07.013. Epub 2015 Jul 29.

PMID:
26226573
19.

Extensive in vitro gastrointestinal digestion markedly reduces the immune-toxicity of Triticum monococcum wheat: implication for celiac disease.

Gianfrani C, Camarca A, Mazzarella G, Di Stasio L, Giardullo N, Ferranti P, Picariello G, Rotondi Aufiero V, Picascia S, Troncone R, Pogna N, Auricchio S, Mamone G.

Mol Nutr Food Res. 2015 Sep;59(9):1844-54. doi: 10.1002/mnfr.201500126. Epub 2015 Jun 26.

PMID:
26016626
20.

Bifidobacteria Enhance Antigen Sampling and Processing by Dendritic Cells in Pediatric Inflammatory Bowel Disease.

Strisciuglio C, Miele E, Giugliano FP, Vitale S, Andreozzi M, Vitale A, Catania MR, Staiano A, Troncone R, Gianfrani C.

Inflamm Bowel Dis. 2015 Jul;21(7):1491-8. doi: 10.1097/MIB.0000000000000389.

PMID:
25895109
21.

Tolerogenic effect of mesenchymal stromal cells on gliadin-specific T lymphocytes in celiac disease.

Ciccocioppo R, Camarca A, Cangemi GC, Radano G, Vitale S, Betti E, Ferrari D, Visai L, Strada E, Badulli C, Locatelli F, Klersy C, Gianfrani C, Corazza GR.

Cytotherapy. 2014 Aug;16(8):1080-91. doi: 10.1016/j.jcyt.2014.03.002. Epub 2014 May 13.

PMID:
24831843
22.

Autophagy genes variants and paediatric Crohn's disease phenotype: a single-centre experience.

Strisciuglio C, Auricchio R, Martinelli M, Staiano A, Giugliano FP, Andreozzi M, De Rosa M, Giannetti E, Gianfrani C, Izzo P, Troncone R, Miele E.

Dig Liver Dis. 2014 Jun;46(6):512-7. doi: 10.1016/j.dld.2014.02.016. Epub 2014 Mar 19.

PMID:
24656308
23.

Cereal-based gluten-free food: how to reconcile nutritional and technological properties of wheat proteins with safety for celiac disease patients.

Lamacchia C, Camarca A, Picascia S, Di Luccia A, Gianfrani C.

Nutrients. 2014 Jan 29;6(2):575-90. doi: 10.3390/nu6020575. Review.

24.

Immunoregulatory pathways are active in the small intestinal mucosa of patients with potential celiac disease.

Borrelli M, Salvati VM, Maglio M, Zanzi D, Ferrara K, Santagata S, Ponticelli D, Aitoro R, Mazzarella G, Lania G, Gianfrani C, Auricchio R, Troncone R.

Am J Gastroenterol. 2013 Nov;108(11):1775-84. doi: 10.1038/ajg.2013.303. Epub 2013 Sep 24.

PMID:
24060758
25.

T300A variant of autophagy ATG16L1 gene is associated with decreased antigen sampling and processing by dendritic cells in pediatric Crohn's disease.

Strisciuglio C, Miele E, Wildenberg ME, Giugliano FP, Andreozzi M, Vitale A, Capasso F, Camarca A, Barone MV, Staiano A, Troncone R, Gianfrani C.

Inflamm Bowel Dis. 2013 Oct;19(11):2339-48. doi: 10.1097/MIB.0b013e3182a6a11c.

PMID:
24022642
26.

Transport across Caco-2 monolayers of peptides arising from in vitro digestion of bovine milk proteins.

Picariello G, Iacomino G, Mamone G, Ferranti P, Fierro O, Gianfrani C, Di Luccia A, Addeo F.

Food Chem. 2013 Aug 15;139(1-4):203-12. doi: 10.1016/j.foodchem.2013.01.063. Epub 2013 Feb 4.

PMID:
23561097
27.

Immunogenic peptides can be detected in whole gluten by transamidating highly susceptible glutamine residues: implication in the search for gluten-free cereals.

Mamone G, Camarca A, Fierro O, Sidney J, Mazzarella G, Addeo F, Auricchio S, Troncone R, Sette A, Gianfrani C.

J Agric Food Chem. 2013 Jan 23;61(3):747-54. doi: 10.1021/jf3040435. Epub 2013 Jan 11.

PMID:
23244345
28.

Immunogenicity of monococcum wheat in celiac patients.

Gianfrani C, Maglio M, Rotondi Aufiero V, Camarca A, Vocca I, Iaquinto G, Giardullo N, Pogna N, Troncone R, Auricchio S, Mazzarella G.

Am J Clin Nutr. 2012 Dec;96(6):1339-45. doi: 10.3945/ajcn.112.040485. Epub 2012 Nov 7.

PMID:
23134879
29.

Shotgun proteome analysis of beer and the immunogenic potential of beer polypeptides.

Picariello G, Mamone G, Nitride C, Addeo F, Camarca A, Vocca I, Gianfrani C, Ferranti P.

J Proteomics. 2012 Oct 22;75(18):5872-82. doi: 10.1016/j.jprot.2012.07.038. Epub 2012 Jul 31.

PMID:
22868252
30.

Short wheat challenge is a reproducible in-vivo assay to detect immune response to gluten.

Camarca A, Radano G, Di Mase R, Terrone G, Maurano F, Auricchio S, Troncone R, Greco L, Gianfrani C.

Clin Exp Immunol. 2012 Aug;169(2):129-36. doi: 10.1111/j.1365-2249.2012.04597.x.

31.

Repertoire of gluten peptides active in celiac disease patients: perspectives for translational therapeutic applications.

Camarca A, Del Mastro A, Gianfrani C.

Endocr Metab Immune Disord Drug Targets. 2012 Jun;12(2):207-19. Review.

PMID:
22385112
32.

Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules.

Sollid LM, Qiao SW, Anderson RP, Gianfrani C, Koning F.

Immunogenetics. 2012 Jun;64(6):455-60. doi: 10.1007/s00251-012-0599-z. Epub 2012 Feb 10. Review.

33.

Peripheral blood immune response elicited by beta-lactoglobulin in childhood cow's milk allergy.

Vocca I, Canani RB, Camarca A, Ruotolo S, Nocerino R, Radano G, Del Mastro A, Troncone R, Gianfrani C.

Pediatr Res. 2011 Dec;70(6):549-54. doi: 10.1203/PDR.0b013e318232739c.

PMID:
21857380
34.

Immunogenicity of two oat varieties, in relation to their safety for celiac patients.

Maglio M, Mazzarella G, Barone MV, Gianfrani C, Pogna N, Gazza L, Stefanile R, Camarca A, Colicchio B, Nanayakkara M, Miele E, Iaquinto G, Giardullo N, Maurano F, Santoro P, Troncone R, Auricchio S.

Scand J Gastroenterol. 2011 Oct;46(10):1194-205. doi: 10.3109/00365521.2011.603159. Epub 2011 Aug 15.

PMID:
21843037
35.

Immunological evaluation of the alcohol-soluble protein fraction from gluten-free grains in relation to celiac disease.

Bergamo P, Maurano F, Mazzarella G, Iaquinto G, Vocca I, Rivelli AR, De Falco E, Gianfrani C, Rossi M.

Mol Nutr Food Res. 2011 Aug;55(8):1266-70. doi: 10.1002/mnfr.201100132. Epub 2011 Jun 28.

PMID:
21710563
36.

Gliadin-mediated proliferation and innate immune activation in celiac disease are due to alterations in vesicular trafficking.

Barone MV, Zanzi D, Maglio M, Nanayakkara M, Santagata S, Lania G, Miele E, Ribecco MT, Maurano F, Auricchio R, Gianfrani C, Ferrini S, Troncone R, Auricchio S.

PLoS One. 2011 Feb 25;6(2):e17039. doi: 10.1371/journal.pone.0017039.

37.

Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease.

Tye-Din JA, Stewart JA, Dromey JA, Beissbarth T, van Heel DA, Tatham A, Henderson K, Mannering SI, Gianfrani C, Jewell DP, Hill AV, McCluskey J, Rossjohn J, Anderson RP.

Sci Transl Med. 2010 Jul 21;2(41):41ra51. doi: 10.1126/scitranslmed.3001012.

38.

Intestinal T cell responses to gluten peptides are largely heterogeneous: implications for a peptide-based therapy in celiac disease.

Camarca A, Anderson RP, Mamone G, Fierro O, Facchiano A, Costantini S, Zanzi D, Sidney J, Auricchio S, Sette A, Troncone R, Gianfrani C.

J Immunol. 2009 Apr 1;182(7):4158-66. doi: 10.4049/jimmunol.0803181.

39.

Gliadin activates HLA class I-restricted CD8+ T cells in celiac disease intestinal mucosa and induces the enterocyte apoptosis.

Mazzarella G, Stefanile R, Camarca A, Giliberti P, Cosentini E, Marano C, Iaquinto G, Giardullo N, Auricchio S, Sette A, Troncone R, Gianfrani C.

Gastroenterology. 2008 Apr;134(4):1017-27. doi: 10.1053/j.gastro.2008.01.008. Epub 2008 Jan 11.

40.

Autoimmunity and celiac disease.

Gianfrani C, Troncone R, La Cava A.

Mini Rev Med Chem. 2008 Feb;8(2):129-34. Review.

PMID:
18289095
41.

Transamidation of wheat flour inhibits the response to gliadin of intestinal T cells in celiac disease.

Gianfrani C, Siciliano RA, Facchiano AM, Camarca A, Mazzeo MF, Costantini S, Salvati VM, Maurano F, Mazzarella G, Iaquinto G, Bergamo P, Rossi M.

Gastroenterology. 2007 Sep;133(3):780-9. Epub 2007 Jun 20.

PMID:
17678925
42.

Gliadin regulates the NK-dendritic cell cross-talk by HLA-E surface stabilization.

Terrazzano G, Sica M, Gianfrani C, Mazzarella G, Maurano F, De Giulio B, de Saint-Mezard S, Zanzi D, Maiuri L, Londei M, Jabri B, Troncone R, Auricchio S, Zappacosta S, Carbone E.

J Immunol. 2007 Jul 1;179(1):372-81.

43.

Highly efficient gluten degradation by lactobacilli and fungal proteases during food processing: new perspectives for celiac disease.

Rizzello CG, De Angelis M, Di Cagno R, Camarca A, Silano M, Losito I, De Vincenzi M, De Bari MD, Palmisano F, Maurano F, Gianfrani C, Gobbetti M.

Appl Environ Microbiol. 2007 Jul;73(14):4499-507. Epub 2007 May 18.

44.

Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats.

D'Argenio G, Petrosino S, Gianfrani C, Valenti M, Scaglione G, Grandone I, Nigam S, Sorrentini I, Mazzarella G, Di Marzo V.

J Mol Med (Berl). 2007 May;85(5):523-30. Epub 2007 Mar 30.

PMID:
17396241
45.

Gliadin-specific type 1 regulatory T cells from the intestinal mucosa of treated celiac patients inhibit pathogenic T cells.

Gianfrani C, Levings MK, Sartirana C, Mazzarella G, Barba G, Zanzi D, Camarca A, Iaquinto G, Giardullo N, Auricchio S, Troncone R, Roncarolo MG.

J Immunol. 2006 Sep 15;177(6):4178-86.

46.

Possible drug targets for celiac disease.

Gianfrani C, Auricchio S, Troncone R.

Expert Opin Ther Targets. 2006 Aug;10(4):601-11. Review.

PMID:
16848695
47.

Adaptive and innate immune responses in celiac disease.

Gianfrani C, Auricchio S, Troncone R.

Immunol Lett. 2005 Jul 15;99(2):141-5. Epub 2005 Apr 7. Review.

PMID:
15876458
48.

IL-10-producing T regulatory type 1 cells and oral tolerance.

Battaglia M, Gianfrani C, Gregori S, Roncarolo MG.

Ann N Y Acad Sci. 2004 Dec;1029:142-53. Review.

PMID:
15681753
49.

Recombinant human interleukin 10 suppresses gliadin dependent T cell activation in ex vivo cultured coeliac intestinal mucosa.

Salvati VM, Mazzarella G, Gianfrani C, Levings MK, Stefanile R, De Giulio B, Iaquinto G, Giardullo N, Auricchio S, Roncarolo MG, Troncone R.

Gut. 2005 Jan;54(1):46-53.

50.

Intranasal administration of a recombinant alpha-gliadin down-regulates the immune response to wheat gliadin in DQ8 transgenic mice.

Senger S, Luongo D, Maurano F, Mazzeo MF, Siciliano RA, Gianfrani C, David C, Troncone R, Auricchio S, Rossi M.

Immunol Lett. 2003 Aug 5;88(2):127-34.

PMID:
12880682

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