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Items: 29

1.

Prognostic implications of additional genomic lesions in adult Philadelphia chromosome-positive acute lymphoblastic leukemia.

Fedullo AL, Messina M, Elia L, Piciocchi A, Gianfelici V, Lauretti A, Soddu S, Puzzolo MC, Minotti C, Ferrara F, Martino B, Chiusolo P, Calafiore V, Paolini S, Vignetti M, Vitale A, Guarini A, Foà R, Chiaretti S.

Haematologica. 2019 Feb;104(2):312-318. doi: 10.3324/haematol.2018.196055. Epub 2018 Sep 6.

2.

IL7R overexpression in adult acute lymphoblastic leukemia is associated to JAK/STAT pathway mutations and identifies patients who could benefit from targeted therapies.

Gianfelici V, Messina M, Paoloni F, Peragine N, Lauretti A, Fedullo AL, Di Giacomo F, Vignetti M, Vitale A, Guarini A, Chiaretti S, Foà R.

Leuk Lymphoma. 2018 Sep 6:1-4. doi: 10.1080/10428194.2018.1499906. [Epub ahead of print] No abstract available.

PMID:
30188230
3.

Biological Aspects of mTOR in Leukemia.

Mirabilii S, Ricciardi MR, Piedimonte M, Gianfelici V, Bianchi MP, Tafuri A.

Int J Mol Sci. 2018 Aug 14;19(8). pii: E2396. doi: 10.3390/ijms19082396. Review.

4.

Rapid identification of BCR/ABL1-like acute lymphoblastic leukaemia patients using a predictive statistical model based on quantitative real time-polymerase chain reaction: clinical, prognostic and therapeutic implications.

Chiaretti S, Messina M, Grammatico S, Piciocchi A, Fedullo AL, Di Giacomo F, Peragine N, Gianfelici V, Lauretti A, Bareja R, Martelli MP, Vignetti M, Apicella V, Vitale A, Li LS, Salek C, Elemento O, Inghirami G, Weinstock DM, Guarini A, Foà R.

Br J Haematol. 2018 Jun;181(5):642-652. doi: 10.1111/bjh.15251. Epub 2018 Apr 19.

PMID:
29675955
5.

High PIM1 expression is a biomarker of T-cell acute lymphoblastic leukemia with JAK/STAT activation or t(6;7)(p21;q34)/TRB@-PIM1 rearrangement.

La Starza R, Messina M, Gianfelici V, Pierini V, Matteucci C, Pierini T, Limongi MZ, Vitale A, Roti G, Chiaretti S, Foà R, Mecucci C.

Leukemia. 2018 Aug;32(8):1807-1810. doi: 10.1038/s41375-018-0031-2. Epub 2018 Feb 2. No abstract available.

PMID:
29479063
6.

Clinical significance of recurrent copy number aberrations in B-lineage acute lymphoblastic leukaemia without recurrent fusion genes across age cohorts.

Messina M, Chiaretti S, Fedullo AL, Piciocchi A, Puzzolo MC, Lauretti A, Gianfelici V, Apicella V, Fazi P, Te Kronnie G, Testi AM, Vitale A, Guarini A, Foà R.

Br J Haematol. 2017 Aug;178(4):583-587. doi: 10.1111/bjh.14721. Epub 2017 Apr 25.

PMID:
28439887
7.

Advances in the Genetics and Therapy of Acute Lymphoblastic Leukemia.

Chiaretti S, Gianfelici V, O'Brien SM, Mullighan CG.

Am Soc Clin Oncol Educ Book. 2016;35:e314-22. doi: 10.14694/EDBK_156628. Review.

8.

RNA sequencing unravels the genetics of refractory/relapsed T-cell acute lymphoblastic leukemia. Prognostic and therapeutic implications.

Gianfelici V, Chiaretti S, Demeyer S, Di Giacomo F, Messina M, La Starza R, Peragine N, Paoloni F, Geerdens E, Pierini V, Elia L, Mancini M, De Propris MS, Apicella V, Gaidano G, Testi AM, Vitale A, Vignetti M, Mecucci C, Guarini A, Cools J, Foà R.

Haematologica. 2016 Aug;101(8):941-50. doi: 10.3324/haematol.2015.139410. Epub 2016 May 5.

9.

Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemia.

La Starza R, Barba G, Demeyer S, Pierini V, Di Giacomo D, Gianfelici V, Schwab C, Matteucci C, Vicente C, Cools J, Messina M, Crescenzi B, Chiaretti S, Foà R, Basso G, Harrison CJ, Mecucci C.

Haematologica. 2016 Aug;101(8):951-8. doi: 10.3324/haematol.2016.143875. Epub 2016 May 5.

10.

Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes.

Messina M, Chiaretti S, Wang J, Fedullo AL, Peragine N, Gianfelici V, Piciocchi A, Brugnoletti F, Di Giacomo F, Pauselli S, Holmes AB, Puzzolo MC, Ceglie G, Apicella V, Mancini M, Te Kronnie G, Testi AM, Vitale A, Vignetti M, Guarini A, Rabadan R, Foà R.

Oncotarget. 2016 Mar 22;7(12):13886-901. doi: 10.18632/oncotarget.7356.

11.

A case of lineage switch from B-cell acute lymphoblastic leukaemia to acute myeloid leukaemia. Role of subclonal/clonal gene mutations.

Della Starza I, Ceglie G, Nunes V, Gianfelici V, Marinelli M, Fuligni F, De Novi LA, De Propris MS, Vitale A, Chiaretti S, Guarini A, Foà R.

Br J Haematol. 2016 Aug;174(4):648-51. doi: 10.1111/bjh.13800. Epub 2015 Oct 12. No abstract available.

PMID:
26456857
12.

CD45 antigen negativity in T-lineage ALL correlates with PTPRC mutation and sensitivity to a selective JAK inhibitor.

Raponi S, Gianfelici V, Chiaretti S, Peragine N, Brugnoletti F, De Propris MS, Marinelli M, Hulselmans G, Aerts S, Geerdens E, Cools J, Foà R, Guarini A.

Br J Haematol. 2015 Dec;171(5):884-7. doi: 10.1111/bjh.13448. Epub 2015 Apr 8. No abstract available.

PMID:
25854815
13.

JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model.

Degryse S, de Bock CE, Cox L, Demeyer S, Gielen O, Mentens N, Jacobs K, Geerdens E, Gianfelici V, Hulselmans G, Fiers M, Aerts S, Meijerink JP, Tousseyn T, Cools J.

Blood. 2014 Nov 13;124(20):3092-100. doi: 10.1182/blood-2014-04-566687. Epub 2014 Sep 5.

14.

Genomic characterization of acute leukemias.

Chiaretti S, Gianfelici V, Ceglie G, Foà R.

Med Princ Pract. 2014;23(6):487-506. doi: 10.1159/000362793. Epub 2014 Jun 20. Review.

15.

DDX3X-MLLT10 fusion in adults with NOTCH1 positive T-cell acute lymphoblastic leukemia.

Brandimarte L, La Starza R, Gianfelici V, Barba G, Pierini V, Di Giacomo D, Cools J, Elia L, Vitale A, Luciano L, Bardi A, Chiaretti S, Matteucci C, Specchia G, Mecucci C.

Haematologica. 2014 May;99(5):64-6. doi: 10.3324/haematol.2013.101725. Epub 2014 Feb 28. No abstract available.

16.

Comprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemia.

Atak ZK, Gianfelici V, Hulselmans G, De Keersmaecker K, Devasia AG, Geerdens E, Mentens N, Chiaretti S, Durinck K, Uyttebroeck A, Vandenberghe P, Wlodarska I, Cloos J, Foà R, Speleman F, Cools J, Aerts S.

PLoS Genet. 2013;9(12):e1003997. doi: 10.1371/journal.pgen.1003997. Epub 2013 Dec 19.

17.

Identification of a novel, recurrent MBTD1-CXorf67 fusion in low-grade endometrial stromal sarcoma.

Dewaele B, Przybyl J, Quattrone A, Finalet Ferreiro J, Vanspauwen V, Geerdens E, Gianfelici V, Kalender Z, Wozniak A, Moerman P, Sciot R, Croce S, Amant F, Vandenberghe P, Cools J, Debiec-Rychter M.

Int J Cancer. 2014 Mar 1;134(5):1112-22. doi: 10.1002/ijc.28440. Epub 2013 Sep 4.

18.

Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia.

De Keersmaecker K, Atak ZK, Li N, Vicente C, Patchett S, Girardi T, Gianfelici V, Geerdens E, Clappier E, Porcu M, Lahortiga I, Lucà R, Yan J, Hulselmans G, Vranckx H, Vandepoel R, Sweron B, Jacobs K, Mentens N, Wlodarska I, Cauwelier B, Cloos J, Soulier J, Uyttebroeck A, Bagni C, Hassan BA, Vandenberghe P, Johnson AW, Aerts S, Cools J.

Nat Genet. 2013 Feb;45(2):186-90. doi: 10.1038/ng.2508. Epub 2012 Dec 23.

19.

Chromosomal aberrations and fusion genes in myeloid malignancies.

Gianfelici V, Lahortiga I, Cools J.

Expert Rev Hematol. 2012 Aug;5(4):381-93. Review.

PMID:
22992233
20.

High accuracy mutation detection in leukemia on a selected panel of cancer genes.

Kalender Atak Z, De Keersmaecker K, Gianfelici V, Geerdens E, Vandepoel R, Pauwels D, Porcu M, Lahortiga I, Brys V, Dirks WG, Quentmeier H, Cloos J, Cuppens H, Uyttebroeck A, Vandenberghe P, Cools J, Aerts S.

PLoS One. 2012;7(6):e38463. doi: 10.1371/journal.pone.0038463. Epub 2012 Jun 4.

21.

Mutation of the receptor tyrosine phosphatase PTPRC (CD45) in T-cell acute lymphoblastic leukemia.

Porcu M, Kleppe M, Gianfelici V, Geerdens E, De Keersmaecker K, Tartaglia M, Foà R, Soulier J, Cauwelier B, Uyttebroeck A, Macintyre E, Vandenberghe P, Asnafi V, Cools J.

Blood. 2012 May 10;119(19):4476-9. doi: 10.1182/blood-2011-09-379958. Epub 2012 Mar 21.

22.

Activation of the NOTCH1 pathway in chronic lymphocytic leukemia.

Gianfelici V.

Haematologica. 2012 Mar;97(3):328-30. doi: 10.3324/haematol.2012.061721. No abstract available.

23.

FISH analysis reveals frequent co-occurrence of 4q24/TET2 and 5q and/or 7q deletions.

La Starza R, Crescenzi B, Nofrini V, Barba G, Matteucci C, Brandimarte L, Pierini V, Testoni N, Musto P, Paolini S, Gianfelici V, Storlazzi CT, Pierini A, Berchicci L, Gorello P, Mecucci C.

Leuk Res. 2012 Jan;36(1):37-41. doi: 10.1016/j.leukres.2011.08.004. Epub 2011 Sep 13.

PMID:
21920603
24.

A novel point mutation within the juxtamembrane domain of the flt3 gene in acute myeloid leukemia.

Gianfelici V, Diverio D, Breccia M, Buffolino S, Derme V, Di Lascio A, Marinelli M, Santangelo S, Meloni G, Foà R.

Ann Hematol. 2011 Jul;90(7):845-6. doi: 10.1007/s00277-010-1092-0. Epub 2010 Oct 6. No abstract available.

PMID:
20924583
25.

Prospective cytomegalovirus monitoring during first-line chemotherapy in patients with acute myeloid leukemia.

Capria S, Gentile G, Capobianchi A, Cardarelli L, Gianfelici V, Trisolini SM, Foà R, Martino P, Meloni G.

J Med Virol. 2010 Jul;82(7):1201-7. doi: 10.1002/jmv.21779.

PMID:
20513085
26.

Late relapse of acute myeloid leukemia with mutated NPM1 after eight years: evidence of NPM1 mutation stability.

Meloni G, Mancini M, Gianfelici V, Martelli MP, Foa R, Falini B.

Haematologica. 2009 Feb;94(2):298-300. doi: 10.3324/haematol.2008.000059. No abstract available. Erratum in: Haematologica. 2009 Aug;94(8):1182.

27.

Is bone marrow trephine biopsy always mandatory in staging Hodgkin's disease?

Cavalieri E, Anselmo AP, Gianfelici V, Frattarelli N, Pescarmona E, Foà R, Pulsoni A.

Haematologica. 2005 Jan;90(1):134-6.

28.

Hodgkin's disease of the nasopharynx: diagnostic and therapeutic approach with a review of the literature.

Anselmo AP, Cavalieri E, Cardarelli L, Gianfelici V, Osti FM, Pescarmona E, Maurizi Enrici R.

Ann Hematol. 2002 Sep;81(9):514-6. Epub 2002 Sep 13. Review.

PMID:
12373352
29.

Dose intensification with autologous stem cell transplantation in relapsed and resistant Hodgkin's disease.

Anselmo AP, Cavalieri E, Meloni G, Alimena G, Cantonetti M, Maurizi Enrici R, Tosti ME, Falchetto Osti M, Gianfelici V, Mandelli F.

Haematologica. 2002 May;87(5):507-11.

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