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Plasma (1 → 3)-β-D-glucan and suPAR levels correlate with neurocognitive performance in people living with HIV on antiretroviral therapy: a CHARTER analysis.

Gianella S, Letendre SL, Iudicello J, Franklin D, Gaufin T, Zhang Y, Porrachia M, Vargas-Meneses M, Ellis RJ, Finkelman M, Hoenigl M.

J Neurovirol. 2019 Jul 11. doi: 10.1007/s13365-019-00775-6. [Epub ahead of print]


Soluble suppression of tumorigenicity 2 levels are not predictive of non-AIDS events during antiretroviral therapy-mediated viral suppression.

Kay A, Moser C, McKhann A, Vargas M, Porrachia M, Gianella S, Hoenigl M.

AIDS. 2019 Jul 1;33(8):1397-1399. doi: 10.1097/QAD.0000000000002228.


Association of Cytomegalovirus DNA and Immunologic Markers of Cardiovascular Disease.

Garg A, Gianella S, Nakazawa M, Trout R, Spector SA.

Open Forum Infect Dis. 2019 Mar 11;6(5):ofz113. doi: 10.1093/ofid/ofz113. eCollection 2019 May.


Effect of Cannabis Use on HIV DNA during Suppressive ART.

Chaillon A, Nakazawa M, Anderson C, Christensen-Quick A, Ellis RJ, Franklin D, Morris SR, Gianella S.

Clin Infect Dis. 2019 May 10. pii: ciz387. doi: 10.1093/cid/ciz387. [Epub ahead of print]


Low Rate of Sex-specific Analyses in Presentations at the Conference on Retroviruses and Opportunistic Infections (CROI) Meeting, 2018: Room to Improve.

Gandhi M, Smeaton LM, Vernon C, Scully EP, Gianella S, Poongulali S, Sheth AN, Van Schalkwyk M, Klingman KL, Short WR, Opollo VS, Cohn SE, Scarsi KK, Firnhaber C, Bares S, Swaminathan S, Mngqibisa R, Connick E; Womenʼs Health Inter-Network Scientific Committee (WHISC).

J Acquir Immune Defic Syndr. 2019 Aug 15;81(5):e158-e160. doi: 10.1097/QAI.0000000000002073. No abstract available.


Subclinical Cytomegalovirus DNA Is Associated with CD4 T Cell Activation and Impaired CD8 T Cell CD107a Expression in People Living with HIV despite Early Antiretroviral Therapy.

Christensen-Quick A, Massanella M, Frick A, Rawlings SA, Spina C, Vargas-Meneses M, Schrier R, Nakazawa M, Anderson C, Gianella S.

J Virol. 2019 Jun 14;93(13). pii: e00179-19. doi: 10.1128/JVI.00179-19. Print 2019 Jul 1.


Genetic network analysis to assess the risk of HIV transmission among MSM seeking partners on the Internet.

Martin TCS, Chaillon A, Graves SK, Lin T, Gianella S, Smith DM, Little SJ, Hoenigl M.

Clin Infect Dis. 2019 Apr 6. pii: ciz278. doi: 10.1093/cid/ciz278. [Epub ahead of print]


Challenges in Quantifying Cytosine Methylation in the HIV Provirus.

LaMere SA, Chaillon A, Huynh C, Smith DM, Gianella S.

MBio. 2019 Jan 22;10(1). pii: e02268-18. doi: 10.1128/mBio.02268-18. Review.


Metabolic Syndrome and Neurocognitive Deficits in HIV Infection.

Yu B, Pasipanodya E, Montoya JL, Moore RC, Gianella S, McCutchan A, Ellis R, Heaton RK, Jeste DV, Moore DJ, Marquine MJ.

J Acquir Immune Defic Syndr. 2019 May 1;81(1):95-101. doi: 10.1097/QAI.0000000000001964.


Soluble Urokinase Plasminogen Activator Receptor (suPAR) is predictive of Non-AIDS Events during Antiretroviral Therapy-mediated Viral Suppression.

Hoenigl M, Moser C, Funderburg N, Bosch R, Kantor A, Zhang Y, Eugen-Olsen J, Finkelman M, Reiser J, Landay A, Moisi D, Lederman MM, Gianella S; ACTG NWCS 411 study team.

Clin Infect Dis. 2018 Nov 12. doi: 10.1093/cid/ciy966. [Epub ahead of print]


Genital HIV-1 Shedding With Dolutegravir (DTG) Plus Lamivudine (3TC) Dual Therapy.

Gianella S, Marconi VC, Berzins B, Benson CA, Sax P, Fichtenbaum CJ, Wilkin T, Vargas M, Deng Q, Oliveira MF, Moser C, Taiwo BO.

J Acquir Immune Defic Syndr. 2018 Dec 15;79(5):e112-e114. doi: 10.1097/QAI.0000000000001863. No abstract available.


Ethical considerations for HIV cure-related research at the end of life.

Dubé K, Gianella S, Concha-Garcia S, Little SJ, Kaytes A, Taylor J, Mathur K, Javadi S, Nathan A, Patel H, Luter S, Philpott-Jones S, Brown B, Smith D.

BMC Med Ethics. 2018 Oct 20;19(1):83. doi: 10.1186/s12910-018-0321-2.


White matter damage, neuroinflammation, and neuronal integrity in HAND.

Alakkas A, Ellis RJ, Watson CW, Umlauf A, Heaton RK, Letendre S, Collier A, Marra C, Clifford DB, Gelman B, Sacktor N, Morgello S, Simpson D, McCutchan JA, Kallianpur A, Gianella S, Marcotte T, Grant I, Fennema-Notestine C; CHARTER Group.

J Neurovirol. 2019 Feb;25(1):32-41. doi: 10.1007/s13365-018-0682-9. Epub 2018 Oct 5.


Influenza Vaccination Can Broadly Activate the HIV Reservoir During Antiretroviral Therapy.

Christensen-Quick A, Chaillon A, Yek C, Zanini F, Jordan P, Ignacio C, Caballero G, Gianella S, Smith D.

J Acquir Immune Defic Syndr. 2018 Nov 1;79(3):e104-e107. doi: 10.1097/QAI.0000000000001829. No abstract available.


The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies.

Namazi G, Fajnzylber JM, Aga E, Bosch RJ, Acosta EP, Sharaf R, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest D, Margolis D, Sneller MC, Little SJ, Gianella S, Smith DM, Kuritzkes DR, Gulick RM, Mellors JW, Mehraj V, Gandhi RT, Mitsuyasu R, Schooley RT, Henry K, Tebas P, Deeks SG, Chun TW, Collier AC, Routy JP, Hecht FM, Walker BD, Li JZ.

J Infect Dis. 2018 Nov 5;218(12):1954-1963. doi: 10.1093/infdis/jiy479.


Willingness to participate in HIV research at the end of life (EOL).

Prakash K, Gianella S, Dubé K, Taylor J, Lee G, Smith DM.

PLoS One. 2018 Jul 23;13(7):e0199670. doi: 10.1371/journal.pone.0199670. eCollection 2018.


A compartmentalized type I interferon response in the gut during chronic HIV-1 infection is associated with immunopathogenesis.

Dillon SM, Guo K, Austin GL, Gianella S, Engen PA, Mutlu EA, Losurdo J, Swanson G, Chakradeo P, Keshavarzian A, Landay AL, Santiago ML, Wilson CC.

AIDS. 2018 Jul 31;32(12):1599-1611. doi: 10.1097/QAD.0000000000001863.


Higher Anti-Cytomegalovirus Immunoglobulin G Concentrations Are Associated With Worse Neurocognitive Performance During Suppressive Antiretroviral Therapy.

Letendre S, Bharti A, Perez-Valero I, Hanson B, Franklin D, Woods SP, Gianella S, de Oliveira MF, Heaton RK, Grant I, Landay AL, Lurain N; CNS HIV AntiRetroviral Therapy Effects Research (CHARTER) Group.

Clin Infect Dis. 2018 Aug 16;67(5):770-777. doi: 10.1093/cid/ciy170.


Use of 'eradication' in HIV cure-related research: a public health debate.

Dubé K, Luter S, Lesnar B, Newton L, Galea J, Brown B, Gianella S.

BMC Public Health. 2018 Feb 13;18(1):245. doi: 10.1186/s12889-018-5141-2.


A Simple Symptom Score for Acute Human Immunodeficiency Virus Infection in a San Diego Community-Based Screening Program.

Lin TC, Gianella S, Tenenbaum T, Little SJ, Hoenigl M.

Clin Infect Dis. 2018 Jun 18;67(1):105-111. doi: 10.1093/cid/cix1130.


Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc.

Chaillon A, Gianella S, Lada SM, Perez-Santiago J, Jordan P, Ignacio C, Karris M, Richman DD, Mehta SR, Little SJ, Wertheim JO, Smith DM.

J Virol. 2018 Jan 17;92(3). pii: e01589-17. doi: 10.1128/JVI.01589-17. Print 2018 Feb 1.


Cytomegalovirus and HIV Persistence: Pouring Gas on the Fire.

Christensen-Quick A, Vanpouille C, Lisco A, Gianella S.

AIDS Res Hum Retroviruses. 2017 Nov;33(S1):S23-S30. doi: 10.1089/aid.2017.0145. Review.


The Importance of Human Immunodeficiency Virus Research for Transgender and Gender-Nonbinary Individuals.

Gianella S, Sonya Haw J, Blumenthal J, Sullivan B, Smith D.

Clin Infect Dis. 2018 Apr 17;66(9):1460-1466. doi: 10.1093/cid/cix990.


Sex-based differences in neurocognitive functioning in HIV-infected young adults.

Burlacu R, Umlauf A, Luca A, Gianella S, Radoi R, Ruta SM, Marcotte TD, Ene L, Achim CL.

AIDS. 2018 Jan 14;32(2):217-225. doi: 10.1097/QAD.0000000000001687.


Effect of cytomegalovirus and Epstein-Barr virus replication on intestinal mucosal gene expression and microbiome composition of HIV-infected and uninfected individuals.

Gianella S, Chaillon A, Mutlu EA, Engen PA, Voigt RM, Keshavarzian A, Losurdo J, Chakradeo P, Lada SM, Nakazawa M, Landay AL.

AIDS. 2017 Sep 24;31(15):2059-2067. doi: 10.1097/QAD.0000000000001579. Erratum in: AIDS. 2018 Aug 24;32(13):1911.


Brief Report: Inflammatory Colonic Innate Lymphoid Cells Are Increased During Untreated HIV-1 Infection and Associated With Markers of Gut Dysbiosis and Mucosal Immune Activation.

Dillon SM, Castleman MJ, Frank DN, Austin GL, Gianella S, Cogswell AC, Landay AL, Barker E, Wilson CC.

J Acquir Immune Defic Syndr. 2017 Dec 1;76(4):431-437. doi: 10.1097/QAI.0000000000001523.


No Substantial Evidence for Sexual Transmission of Minority HIV Drug Resistance Mutations in Men Who Have Sex with Men.

Chaillon A, Nakazawa M, Wertheim JO, Little SJ, Smith DM, Mehta SR, Gianella S.

J Virol. 2017 Oct 13;91(21). pii: e00769-17. doi: 10.1128/JVI.00769-17. Print 2017 Nov 1.


Evaluation of the Aptima HIV-1 Quant Dx Assay for HIV-1 RNA Quantitation in Different Biological Specimen Types.

Yek C, Massanella M, Peling T, Lednovich K, Nair SV, Worlock A, Vargas M, Gianella S, Ellis RJ, Strain MC, Busch MP, Nugent CT, Richman DD.

J Clin Microbiol. 2017 Aug;55(8):2544-2553. doi: 10.1128/JCM.00425-17. Epub 2017 Jun 7.


Longitudinal Viral Dynamics in Semen During Early HIV Infection.

Morris SR, Zhao M, Smith DM, Vargas MV, Little SJ, Gianella S.

Clin Infect Dis. 2017 Feb 15;64(4):428-434. doi: 10.1093/cid/ciw784.


Elevated cytomegalovirus IgG antibody levels are associated with HIV-1 disease progression and immune activation.

Patel EU, Gianella S, Newell K, Tobian AA, Kirkpatrick AR, Nalugoda F, Grabowski MK, Gray RH, Serwadda D, Quinn TC, Redd AD, Reynolds SJ.

AIDS. 2017 Mar 27;31(6):807-813. doi: 10.1097/QAD.0000000000001412.


Early Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations.

Oliveira MF, Chaillon A, Nakazawa M, Vargas M, Letendre SL, Strain MC, Ellis RJ, Morris S, Little SJ, Smith DM, Gianella S.

PLoS Pathog. 2017 Jan 3;13(1):e1006112. doi: 10.1371/journal.ppat.1006112. eCollection 2017 Jan.


Low abundance of colonic butyrate-producing bacteria in HIV infection is associated with microbial translocation and immune activation.

Dillon SM, Kibbie J, Lee EJ, Guo K, Santiago ML, Austin GL, Gianella S, Landay AL, Donovan AM, Frank DN, McCARTER MD, Wilson CC.

AIDS. 2017 Feb 20;31(4):511-521. doi: 10.1097/QAD.0000000000001366.


Increased cell-free mitochondrial DNA is a marker of ongoing inflammation and better neurocognitive function in virologically suppressed HIV-infected individuals.

Pérez-Santiago J, De Oliveira MF, Var SR, Day TRC, Woods SP, Gianella S, Mehta SR.

J Neurovirol. 2017 Apr;23(2):283-289. doi: 10.1007/s13365-016-0497-5. Epub 2016 Dec 5.


Compartmentalized HIV rebound in the central nervous system after interruption of antiretroviral therapy.

Gianella S, Kosakovsky Pond SL, Oliveira MF, Scheffler K, Strain MC, De la Torre A, Letendre S, Smith DM, Ellis RJ.

Virus Evol. 2016 Aug 3;2(2):vew020. eCollection 2016 Jul.


Can research at the end of life be a useful tool to advance HIV cure?

Gianella S, Taylor J, Brown TR, Kaytes A, Achim CL, Moore DJ, Little SJ, Ellis RJ, Smith DM.

AIDS. 2017 Jan 2;31(1):1-4. No abstract available.


(1→3)-β-d-Glucan: A Biomarker for Microbial Translocation in Individuals with Acute or Early HIV Infection?

Hoenigl M, Pérez-Santiago J, Nakazawa M, de Oliveira MF, Zhang Y, Finkelman MA, Letendre S, Smith D, Gianella S.

Front Immunol. 2016 Oct 3;7:404. eCollection 2016.


Cytomegalovirus and HIV: A Dangerous Pas de Deux.

Gianella S, Letendre S.

J Infect Dis. 2016 Oct 1;214 Suppl 2:S67-74. doi: 10.1093/infdis/jiw217. Review.


Asymptomatic CMV Replication During Early Human Immunodeficiency Virus (HIV) Infection Is Associated With Lower CD4/CD8 Ratio During HIV Treatment.

Smith DM, Nakazawa M, Freeman ML, Anderson CM, Oliveira MF, Little SJ, Gianella S.

Clin Infect Dis. 2016 Dec 1;63(11):1517-1524. Epub 2016 Sep 6.


Rapid HIV Viral Load Suppression in those Initiating Antiretroviral Therapy at First Visit after HIV Diagnosis.

Hoenigl M, Chaillon A, Moore DJ, Morris SR, Mehta SR, Gianella S, Amico KR, Little SJ.

Sci Rep. 2016 Sep 6;6:32947. doi: 10.1038/srep32947.


HIV Trafficking Between Blood and Semen During Early Untreated HIV Infection.

Chaillon A, Smith DM, Vanpouille C, Lisco A, Jordan P, Caballero G, Vargas M, Gianella S, Mehta SR.

J Acquir Immune Defic Syndr. 2017 Jan 1;74(1):95-102.


Standard vaccines increase HIV-1 transcription during antiretroviral therapy.

Yek C, Gianella S, Plana M, Castro P, Scheffler K, García F, Massanella M, Smith DM.

AIDS. 2016 Sep 24;30(15):2289-98. doi: 10.1097/QAD.0000000000001201.


Characterizing the multiplicity of HIV founder variants during sexual transmission among MSM.

Chaillon A, Gianella S, Little SJ, Caballero G, Barin F, Kosakovsky Pond S, Richman DD, Smith DM, Mehta SR.

Virus Evol. 2016 Jun 8;2(1):vew012. doi: 10.1093/ve/vew012. eCollection 2016 Jan.


Immunological Signaling During Herpes Simplex Virus-2 and Cytomegalovirus Vaginal Shedding After Initiation of Antiretroviral Treatment.

Nason MC, Patel EU, Kirkpatrick AR, Prodger JL, Shahabi K, Tobian AA, Gianella S, Kalibbala S, Ssebbowa P, Kaul R, Gray RH, Quinn TC, Serwadda D, Reynolds SJ, Redd AD.

Open Forum Infect Dis. 2016 Apr 6;3(2):ofw073. doi: 10.1093/ofid/ofw073. eCollection 2016 Mar.


Shedding of Hepatitis C Virus in Semen of Human Immunodeficiency Virus-Infected Men.

Turner SS, Gianella S, Yip MJ, van Seggelen WO, Gillies RD, Foster AL, Barbati ZR, Smith DM, Fierer DS.

Open Forum Infect Dis. 2016 Mar 11;3(2):ofw057. doi: 10.1093/ofid/ofw057. eCollection 2016 Mar.


Travel Pattern and Prescription Analysis at a Single Travel Clinic Specialized for Yellow Fever Vaccination in South Korea.

Chin BS, Kim JY, Gianella S, Lee M.

Infect Chemother. 2016 Mar;48(1):20-30. doi: 10.3947/ic.2016.48.1.20. Epub 2016 Mar 31.


Reply to Barrett, et al.

Freeman ML, Mudd JC, Shive CL, Younes SA, Panigrahi S, Sieg SF, Lee SA, Hunt PW, Calabrese LH, Gianella S, Rodriguez B, Lederman MM.

Clin Infect Dis. 2016 Jun 1;62(11):1468-9. doi: 10.1093/cid/ciw152. Epub 2016 Mar 21. No abstract available.


(1→3)-β-D-Glucan Levels Correlate With Neurocognitive Functioning in HIV-Infected Persons on Suppressive Antiretroviral Therapy: A Cohort Study.

Hoenigl M, de Oliveira MF, Pérez-Santiago J, Zhang Y, Morris S, McCutchan AJ, Finkelman M, Marcotte TD, Ellis RJ, Gianella S.

Medicine (Baltimore). 2016 Mar;95(11):e3162. doi: 10.1097/MD.0000000000003162. Erratum in: Medicine (Baltimore). 2016 May 20;95(20):e9582.


Barriers to a cure for HIV in women.

Gianella S, Tsibris A, Barr L, Godfrey C.

J Int AIDS Soc. 2016 Feb 18;19(1):20706. doi: 10.7448/IAS.19.1.20706. eCollection 2016. Review.


Signs or Symptoms of Acute HIV Infection in a Cohort Undergoing Community-Based Screening.

Hoenigl M, Green N, Camacho M, Gianella S, Mehta SR, Smith DM, Little SJ.

Emerg Infect Dis. 2016 Mar;22(3):532-4. doi: 10.3201/eid2203.151607.


Replication of Human Herpesviruses Is Associated with Higher HIV DNA Levels during Antiretroviral Therapy Started at Early Phases of HIV Infection.

Gianella S, Anderson CM, Var SR, Oliveira MF, Lada SM, Vargas MV, Massanella M, Little SJ, Richman DD, Strain MC, Pérez-Santiago J, Smith DM.

J Virol. 2016 Mar 28;90(8):3944-3952. doi: 10.1128/JVI.02638-15. Print 2016 Apr.

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