Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 13

1.

Blockade of protease-activated receptor-4 (PAR4) provides robust antithrombotic activity with low bleeding.

Wong PC, Seiffert D, Bird JE, Watson CA, Bostwick JS, Giancarli M, Allegretto N, Hua J, Harden D, Guay J, Callejo M, Miller MM, Lawrence RM, Banville J, Guy J, Maxwell BD, Priestley ES, Marinier A, Wexler RR, Bouvier M, Gordon DA, Schumacher WA, Yang J.

Sci Transl Med. 2017 Jan 4;9(371). pii: eaaf5294. doi: 10.1126/scitranslmed.aaf5294.

PMID:
28053157
2.

Prediction of the therapeutic index of marketed anti-coagulants and anti-platelet agents by guinea pig models of thrombosis and hemostasis.

Bird JE, Giancarli MR, Allegretto N, Barbera F, Wong P, Schumacher WA, Ogletree ML, Seiffert D.

Thromb Res. 2008;123(1):146-58. doi: 10.1016/j.thromres.2008.03.010. Epub 2008 May 14.

PMID:
18479740
3.

(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(1-methyl-1h-1,2,4-triazol-5-yl)amino)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid (BMS-644950): a rationally designed orally efficacious 3-hydroxy-3-methylglutaryl coenzyme-a reductase inhibitor with reduced myotoxicity potential.

Ahmad S, Madsen CS, Stein PD, Janovitz E, Huang C, Ngu K, Bisaha S, Kennedy LJ, Chen BC, Zhao R, Sitkoff D, Monshizadegan H, Yin X, Ryan CS, Zhang R, Giancarli M, Bird E, Chang M, Chen X, Setters R, Search D, Zhuang S, Nguyen-Tran V, Cuff CA, Harrity T, Darienzo CJ, Li T, Reeves RA, Blanar MA, Barrish JC, Zahler R, Robl JA.

J Med Chem. 2008 May 8;51(9):2722-33. doi: 10.1021/jm800001n. Epub 2008 Apr 15.

PMID:
18412317
4.

Novel dual action AT1 and ETA receptor antagonists reduce blood pressure in experimental hypertension.

Kowala MC, Murugesan N, Tellew J, Carlson K, Monshizadegan H, Ryan C, Gu Z, Kane B, Fadnis L, Baska RA, Beyer S, Arthur S, Dickinson K, Zhang D, Perrone M, Ferrer P, Giancarli M, Baumann J, Bird E, Panchal B, Yang Y, Trippodo N, Barrish J, Macor JE.

J Pharmacol Exp Ther. 2004 Apr;309(1):275-84. Epub 2004 Jan 12.

PMID:
14718594
5.

Increased severity of glomerulonephritis in C-C chemokine receptor 2 knockout mice.

Bird JE, Giancarli MR, Kurihara T, Kowala MC, Valentine MT, Gitlitz PH, Pandya DG, French MH, Durham SK.

Kidney Int. 2000 Jan;57(1):129-36.

6.

Biphenylsulfonamide endothelin antagonists: structure-activity relationships of a series of mono- and disubstituted analogues and pharmacology of the orally active endothelin antagonist 2'-amino-N- (3,4-dimethyl-5-isoxazolyl)-4'-(2-methylpropyl)[1, 1'-biphenyl]-2-sulfonamide (BMS-187308).

Murugesan N, Gu Z, Stein PD, Bisaha S, Spergel S, Girotra R, Lee VG, Lloyd J, Misra RN, Schmidt J, Mathur A, Stratton L, Kelly YF, Bird E, Waldron T, Liu EC, Zhang R, Lee H, Serafino R, Abboa-Offei B, Mathers P, Giancarli M, Seymour AA, Webb ML, Hunt JT, et al.

J Med Chem. 1998 Dec 17;41(26):5198-218.

PMID:
9857090
7.

Captopril prevents nephropathy in HIV-transgenic mice.

Bird JE, Durham SK, Giancarli MR, Gitlitz PH, Pandya DG, Dambach DM, Mozes MM, Kopp JB.

J Am Soc Nephrol. 1998 Aug;9(8):1441-7.

8.
9.

Effects of endothelin in radiocontrast-induced nephropathy in rats are mediated through endothelin-A receptors.

Bird JE, Giancarli MR, Megill JR, Durham SK.

J Am Soc Nephrol. 1996 Aug;7(8):1153-7.

10.

A role for endothelin ETA receptors in regulation of renal function in spontaneously hypertensive rats.

Bird JE, Webb ML, Giancarli MR, Chao C, Dorso CR, Asaad MM.

Eur J Pharmacol. 1995 Dec 27;294(1):183-9.

PMID:
8788430
11.

Cardiovascular effects of the novel dual inhibitor of neutral endopeptidase and angiotensin-converting enzyme BMS-182657 in experimental hypertension and heart failure.

Trippodo NC, Robl JA, Asaad MM, Bird JE, Panchal BC, Schaeffer TR, Fox M, Giancarli MR, Cheung HS.

J Pharmacol Exp Ther. 1995 Nov;275(2):745-52.

PMID:
7473162
12.

Comparison of a novel ETA receptor antagonist and phosphoramidon in renal ischemia.

Bird JE, Webb ML, Wasserman AJ, Liu EC, Giancarli MR, Durham SK.

Pharmacology. 1995 Jan;50(1):9-23.

PMID:
7899482
13.

Thrombin inhibition compared with other antithrombotic drugs in rats.

Schumacher WA, Heran CH, Steinbacher TE, Megill JR, Bird JE, Giancarli MR, Durham SK.

Thromb Res. 1992 Oct 15;68(2):157-66.

PMID:
1475778

Supplemental Content

Loading ...
Support Center