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Items: 1 to 50 of 335

1.

Staphylococcus Aureus Osteomyelitis as an Inducer of Tolerance to Escherichia Coli Pyelonephritis: an Experimental Study.

Goumenos S, Savvidou O, Renieris G, Gkavogianni T, Papagelopoulos PJ, Giamarellos-Bourboulis EJ.

Sci Rep. 2020 Jan 28;10(1):1345. doi: 10.1038/s41598-020-58420-w.

2.

Clinical efficacy of complement c5a inhibition by ifx-1 in hidradenitis suppurativa: an open-label single-arm trial in patients not eligible for adalimumab.

Giamarellos-Bourboulis EJ, Argyropoulou M, Kanni T, Spyridopoulos T, Otto I, Zenker O, Guo R, Riedemann NC.

Br J Dermatol. 2020 Jan 18. doi: 10.1111/bjd.18877. [Epub ahead of print]

PMID:
31954061
3.

Association of modulation of pro-inflammatory responses by dectin-2 with preterm delivery: An experimental model.

Liassidou A, Renieris G, Droggiti DI, Gkavogianni T, Liassides C, Sabracos L, Giamarellos-Bourboulis EJ, Siristatidis CS.

Am J Reprod Immunol. 2020 Mar;83(3):e13216. doi: 10.1111/aji.13216. Epub 2020 Jan 2.

PMID:
31814179
4.

The early change of SOFA score as a prognostic marker of 28-day sepsis mortality: analysis through a derivation and a validation cohort.

Karakike E, Kyriazopoulou E, Tsangaris I, Routsi C, Vincent JL, Giamarellos-Bourboulis EJ.

Crit Care. 2019 Nov 29;23(1):387. doi: 10.1186/s13054-019-2665-5.

5.

Survival benefit associated with clarithromycin in severe community-acquired pneumonia: A matched comparator study.

Kyriazopoulou E, Sinapidis D, Halvatzis S, Velissaris D, Alexiou N, Kosmas V, Adami ME, Kyprianou M, Kyprianou A, Stefos A, Lada M, Koutoukas P, Pavlaki M, Kyriakoudi A, Makina A, Gogos C, Niederman MS, Giamarellos-Bourboulis EJ.

Int J Antimicrob Agents. 2020 Jan;55(1):105836. doi: 10.1016/j.ijantimicag.2019.10.017. Epub 2019 Nov 5.

PMID:
31704213
6.

Identification of suitable controls for miRNA quantification in T-cells and whole blood cells in sepsis.

Hirschberger S, Hübner M, Strauß G, Effinger D, Bauer M, Weis S, Giamarellos-Bourboulis EJ, Kreth S.

Sci Rep. 2019 Oct 31;9(1):15735. doi: 10.1038/s41598-019-51782-w.

7.

Current gaps in sepsis immunology: new opportunities for translational research.

Rubio I, Osuchowski MF, Shankar-Hari M, Skirecki T, Winkler MS, Lachmann G, La Rosée P, Monneret G, Venet F, Bauer M, Brunkhorst FM, Kox M, Cavaillon JM, Uhle F, Weigand MA, Flohé SB, Wiersinga WJ, Martin-Fernandez M, Almansa R, Martin-Loeches I, Torres A, Giamarellos-Bourboulis EJ, Girardis M, Cossarizza A, Netea MG, van der Poll T, Scherag A, Meisel C, Schefold JC, Bermejo-Martín JF.

Lancet Infect Dis. 2019 Dec;19(12):e422-e436. doi: 10.1016/S1473-3099(19)30567-5. Epub 2019 Oct 17. Review.

PMID:
31630991
8.

Past history of stage I/II solid tumor malignancy impacts considerably on sepsis mortality: a propensity score matching analysis from the hellenic sepsis study group.

Dimopoulos G, Rovina N, Patrani M, Antoniadou E, Konstantonis D, Vryza K, Vlachogianni G, Kyprianou M, Routsi C, Giamarellos-Bourboulis EJ; Hellenic Sepsis Study Group.

BMC Infect Dis. 2019 Oct 7;19(1):831. doi: 10.1186/s12879-019-4448-7.

9.

Single nucleotide polymorphisms of Toll-like receptor-4 and of autophagy-related gene 16 like-1 gene for predisposition of premature delivery: A prospective study.

Liassides C, Papadopoulos A, Siristatidis C, Damoraki G, Liassidou A, Chrelias C, Kassanos D, Giamarellos-Bourboulis EJ.

Medicine (Baltimore). 2019 Oct;98(40):e17313. doi: 10.1097/MD.0000000000017313.

10.

Microbiology of acute bacterial skin and skin-structure infections in Greece: A proposed clinical prediction score for the causative pathogen.

Nodaras C, Kotsaki A, Tziolos N, Kontopoulou T, Akinosoglou K, Chrisanthakopoulou M, Kranidioti E, Kritselis I, Voloudakis N, Vittoros V, Gogkou A, Fillas I, Toutouzas KG, Bristianou M, Tsoutsos D, Christaki E, Adamis G, Kaziani K, Tsironis C, Lada M, Kokkinakis E, Sympardi S, Koutelidakis IM, Karkamanis A, Pantazi A, Bayram C, Alexiou Z, Mousoulis G, Gogos C, O'Hare M, Griffiths D, MacGowan A, Sambatakou H, Giamarellos-Bourboulis EJ.

Int J Antimicrob Agents. 2019 Dec;54(6):750-756. doi: 10.1016/j.ijantimicag.2019.08.020. Epub 2019 Aug 31.

PMID:
31479742
11.

Staphylococcus aureus and host interaction in the flare-ups of hidradenitis suppurativa.

Giamarellos-Bourboulis EJ.

Br J Dermatol. 2019 Nov;181(5):892-893. doi: 10.1111/bjd.18320. Epub 2019 Aug 12. No abstract available.

PMID:
31403170
12.

Susceptibility profiles and clinical efficacy of antifungals against candida bloodstream isolates from critically ill patients: Focus on intravenous itraconazole.

Giamarellos-Bourboulis EJ, Stamou A, Maraki S, Solomonidi N, Belesiotou E, Pistiki A, Antoniadou E, Vlachogianni G, Mandragos K, Tasioudis C, Katsenos C, Routsi C, Samonis G, Dimopoulos G.

Int J Antimicrob Agents. 2019 Oct;54(4):471-477. doi: 10.1016/j.ijantimicag.2019.06.019. Epub 2019 Jul 2.

PMID:
31271830
13.

Association between genotypes of rs34436714 of NLRP12 and serum tumor necrosis factor-alpha in inflammatory bowel disease: A case-control study.

Dellaporta E, Lazaridis LD, Koussoulas V, Netea MG, Giamarellos-Bourboulis EJ, Triantafyllou K.

Medicine (Baltimore). 2019 Jun;98(23):e15913. doi: 10.1097/MD.0000000000015913.

14.

Association of the early absolute CD64-expressing neutrophil count and sepsis outcome.

Xini A, Pistiki A, Lada M, Giamarellos-Bourboulis EJ, Dimopoulos G.

Eur J Clin Microbiol Infect Dis. 2019 Jun;38(6):1123-1128. doi: 10.1007/s10096-019-03507-0. Epub 2019 Apr 23.

PMID:
31011855
15.

Pharmacological management of sepsis in adults with a focus on the current gold standard treatments and promising adjunctive strategies: evidence from the last five years.

Kyriazopoulou E, Giamarellos-Bourboulis EJ.

Expert Opin Pharmacother. 2019 Jun;20(8):991-1007. doi: 10.1080/14656566.2019.1589451. Epub 2019 Mar 17. Review.

PMID:
30879348
16.

Macrophage Activation-Like Syndrome: A Distinct Entity Leading to Early Death in Sepsis.

Karakike E, Giamarellos-Bourboulis EJ.

Front Immunol. 2019 Jan 31;10:55. doi: 10.3389/fimmu.2019.00055. eCollection 2019. Review.

17.

Early changes of the heat-shock protein 60 to 70 ratio as prediction of miscarriage in pregnancy.

Makri A, Siristatidis C, Chrelias C, Christodoulaki C, Evangelinakis N, Kassanos D, Giamarellos-Bourboulis EJ, Pistiki A.

Am J Reprod Immunol. 2019 Mar;81(3):e13087. doi: 10.1111/aji.13087. Epub 2019 Feb 14.

PMID:
30614112
18.

The IL-1 Pathway Is Hyperactive in Hidradenitis Suppurativa and Contributes to Skin Infiltration and Destruction.

Witte-Händel E, Wolk K, Tsaousi A, Irmer ML, Mößner R, Shomroni O, Lingner T, Witte K, Kunkel D, Salinas G, Jodl S, Schmidt N, Sterry W, Volk HD, Giamarellos-Bourboulis EJ, Pokrywka A, Döcke WD, Schneider-Burrus S, Sabat R.

J Invest Dermatol. 2019 Jun;139(6):1294-1305. doi: 10.1016/j.jid.2018.11.018. Epub 2018 Dec 5.

PMID:
30528824
19.

Daptomycin as adjunctive treatment for experimental infection by Acinetobacter baumannii with resistance to colistin.

Poulakou G, Renieris G, Sabrakos L, Zarkotou O, Themeli-Digalaki K, Perivolioti E, Kraniotaki E, Giamarellos-Bourboulis EJ, Zavras N.

Int J Antimicrob Agents. 2019 Feb;53(2):190-194. doi: 10.1016/j.ijantimicag.2018.10.024. Epub 2018 Nov 2.

PMID:
30391645
20.

MicroRNAs 143 and 150 in whole blood enable detection of T-cell immunoparalysis in sepsis.

Möhnle P, Hirschberger S, Hinske LC, Briegel J, Hübner M, Weis S, Dimopoulos G, Bauer M, Giamarellos-Bourboulis EJ, Kreth S.

Mol Med. 2018 Oct 17;24(1):54. doi: 10.1186/s10020-018-0056-z.

21.

Effect and Safety of Meropenem-Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections: The TANGO II Randomized Clinical Trial.

Wunderink RG, Giamarellos-Bourboulis EJ, Rahav G, Mathers AJ, Bassetti M, Vazquez J, Cornely OA, Solomkin J, Bhowmick T, Bishara J, Daikos GL, Felton T, Furst MJL, Kwak EJ, Menichetti F, Oren I, Alexander EL, Griffith D, Lomovskaya O, Loutit J, Zhang S, Dudley MN, Kaye KS.

Infect Dis Ther. 2018 Dec;7(4):439-455. doi: 10.1007/s40121-018-0214-1. Epub 2018 Oct 1.

22.

Late Peaks of HMGB1 and Sepsis Outcome: Evidence For Synergy With Chronic Inflammatory Disorders.

Karakike E, Adami ME, Lada M, Gkavogianni T, Koutelidakis IM, Bauer M, Giamarellos-Bourboulis EJ, Tsangaris I.

Shock. 2019 Sep;52(3):334-339. doi: 10.1097/SHK.0000000000001265.

PMID:
30239421
23.

Immunosuppression is Inappropriately Qualifying the Immune Status of Septic and SIRS Patients.

Cavaillon JM, Giamarellos-Bourboulis EJ.

Shock. 2019 Sep;52(3):307-317. doi: 10.1097/SHK.0000000000001266.

PMID:
30239420
24.

Cost-savings of adalimumab in hidradenitis suppurativa: a retrospective analysis of a real-world cohort.

Argyropoulou M, Kanni T, Kyprianou M, Melachroinopoulos N, Giamarellos-Bourboulis EJ.

Br J Dermatol. 2019 May;180(5):1161-1168. doi: 10.1111/bjd.17151. Epub 2018 Nov 4.

PMID:
30192377
25.

A prognostic score for the resolution of bacteremia by Gram-negative bacteria resistant to carbapenems.

Giamarellos-Bourboulis EJ, Kotsaki A, Routsi C, Graziano E, Righi E, Bassetti M.

Eur J Clin Microbiol Infect Dis. 2018 Nov;37(11):2083-2089. doi: 10.1007/s10096-018-3342-3. Epub 2018 Aug 6.

PMID:
30083886
26.

Progression into sepsis: an individualized process varying by the interaction of comorbidities with the underlying infection.

Sinapidis D, Kosmas V, Vittoros V, Koutelidakis IM, Pantazi A, Stefos A, Katsaros KE, Akinosoglou K, Bristianou M, Toutouzas K, Chrisofos M, Giamarellos-Bourboulis EJ.

BMC Infect Dis. 2018 May 29;18(1):242. doi: 10.1186/s12879-018-3156-z.

27.

Low-dose hydrocortisone prolongs survival in a lethal sepsis model in adrenalectomized rats.

Doulias T, Quickert S, Weis S, Claus RA, Kontopoulou K, Giamarellos-Bourboulis EJ, Bauer M, Koutelidakis IM.

J Surg Res. 2018 Jul;227:72-80. doi: 10.1016/j.jss.2018.02.011. Epub 2018 Mar 12.

PMID:
29804866
28.

Early increase of VEGF-A is associated with resolution of ventilator-associated pneumonia: Clinical and experimental evidence.

Strouvalis I, Routsi C, Adamopoulou M, Raftogiannis M, Renieris G, Orfanos SE, Kotanidou A, Sabracos L, Giamarellos-Bourboulis EJ.

Respirology. 2018 Oct;23(10):942-949. doi: 10.1111/resp.13320. Epub 2018 May 9.

PMID:
29741298
29.

Correction to: Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritable Bowel Syndrome: Association with Intestinal Bacterial Overgrowth.

Leventogiannis K, Gkolfakis P, Spithakis G, Tsatali A, Pistiki A, Sioulas A, Giamarellos-Bourboulis EJ, Triantafyllou K.

Probiotics Antimicrob Proteins. 2019 Jun;11(2):635-637. doi: 10.1007/s12602-018-9412-0.

30.
31.

Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritable Bowel Syndrome: Association with Intestinal Bacterial Overgrowth.

Leventogiannis K, Gkolfakis P, Spithakis G, Tsatali A, Pistiki A, Sioulas A, Giamarellos-Bourboulis EJ, Triantafyllou K.

Probiotics Antimicrob Proteins. 2019 Jun;11(2):627-634. doi: 10.1007/s12602-018-9401-3. Erratum in: Probiotics Antimicrob Proteins. 2018 Mar 28;:.

32.

Increases in inflammatory and CD14dim/CD16pos/CD45pos patrolling monocytes in sepsis: correlation with final outcome.

Gainaru G, Papadopoulos A, Tsangaris I, Lada M, Giamarellos-Bourboulis EJ, Pistiki A.

Crit Care. 2018 Mar 3;22(1):56. doi: 10.1186/s13054-018-1977-1.

33.

Effect of Meropenem-Vaborbactam vs Piperacillin-Tazobactam on Clinical Cure or Improvement and Microbial Eradication in Complicated Urinary Tract Infection: The TANGO I Randomized Clinical Trial.

Kaye KS, Bhowmick T, Metallidis S, Bleasdale SC, Sagan OS, Stus V, Vazquez J, Zaitsev V, Bidair M, Chorvat E, Dragoescu PO, Fedosiuk E, Horcajada JP, Murta C, Sarychev Y, Stoev V, Morgan E, Fusaro K, Griffith D, Lomovskaya O, Alexander EL, Loutit J, Dudley MN, Giamarellos-Bourboulis EJ.

JAMA. 2018 Feb 27;319(8):788-799. doi: 10.1001/jama.2018.0438.

34.

Reduced circulating B cells and plasma IgM levels are associated with decreased survival in sepsis - A meta-analysis.

Krautz C, Maier SL, Brunner M, Langheinrich M, Giamarellos-Bourboulis EJ, Gogos C, Armaganidis A, Kunath F, Grützmann R, Weber GF.

J Crit Care. 2018 Jun;45:71-75. doi: 10.1016/j.jcrc.2018.01.013. Epub 2018 Feb 14.

PMID:
29413726
35.

Transient Effects of Anesthesia on Leukocyte Apoptosis and Monocyte Cytokine Stimulation: A Clinical Study.

Matsota P, Kostopanagiotou G, Kalimeris K, Pandazi A, Kotsaki A, Kontogiannopoulou S, Giamarellos-Bourboulis EJ.

Immunol Invest. 2018 May;47(4):327-334. doi: 10.1080/08820139.2018.1435690. Epub 2018 Feb 7.

PMID:
29412077
36.

Complement activation in hidradenitis suppurativa: a new pathway of pathogenesis?

Kanni T, Zenker O, Habel M, Riedemann N, Giamarellos-Bourboulis EJ.

Br J Dermatol. 2018 Aug;179(2):413-419. doi: 10.1111/bjd.16428. Epub 2018 May 10.

PMID:
29405257
37.

Haplotypes composed of minor frequency single nucleotide polymorphisms of the TNF gene protect from progression into sepsis: A study using the new sepsis classification.

Retsas T, Huse K, Lazaridis LD, Karampela N, Bauer M, Platzer M, Kolonia V, Papageorgiou E, Giamarellos-Bourboulis EJ, Dimopoulos G.

Int J Infect Dis. 2018 Feb;67:102-106. doi: 10.1016/j.ijid.2017.12.008. Epub 2017 Dec 21.

38.

Infection-free Clinical Response Among Patients With Hidradenitis Suppurativa Who Were Treated With Adalimumab: Results from Two Phase 3 Studies.

Giamarellos-Bourboulis EJ, Sobell J, Ryan C, Wolkenstein PJ, Geng Z, Mulder GD.

Wounds. 2017 Nov;29(11):E98-E102.

39.

MABp1 Targeting IL-1α for Moderate to Severe Hidradenitis Suppurativa Not Eligible for Adalimumab: A Randomized Study.

Kanni T, Argyropoulou M, Spyridopoulos T, Pistiki A, Stecher M, Dinarello CA, Simard J, Giamarellos-Bourboulis EJ.

J Invest Dermatol. 2018 Apr;138(4):795-801. doi: 10.1016/j.jid.2017.10.030. Epub 2017 Nov 10.

40.

Reply to Corona and Cattaneo.

Nation RL, Garonzik SM, Thamlikitkul V, Giamarellos-Bourboulis EJ, Forrest A, Paterson DL, Li J, Silveira FP.

Clin Infect Dis. 2017 Sep 1;65(5):870-871. doi: 10.1093/cid/cix390. No abstract available.

41.

Angiopoietin-2 Levels as Predictors of Outcome in Mechanically Ventilated Patients with Acute Respiratory Distress Syndrome.

Tsangaris I, Tsantes A, Vrigkou E, Kopterides P, Pelekanou A, Zerva K, Antonakos G, Konstantonis D, Mavrou I, Tsaknis G, Kyriazopoulou E, Mouktaroudi M, Kokori S, Orfanos SE, Giamarellos-Bourboulis EJ, Armaganidis A.

Dis Markers. 2017;2017:6758721. doi: 10.1155/2017/6758721. Epub 2017 Aug 29.

42.

Macrophage activation-like syndrome: an immunological entity associated with rapid progression to death in sepsis.

Kyriazopoulou E, Leventogiannis K, Norrby-Teglund A, Dimopoulos G, Pantazi A, Orfanos SE, Rovina N, Tsangaris I, Gkavogianni T, Botsa E, Chassiou E, Kotanidou A, Kontouli C, Chaloulis P, Velissaris D, Savva A, Cullberg JS, Akinosoglou K, Gogos C, Armaganidis A, Giamarellos-Bourboulis EJ; Hellenic Sepsis Study Group.

BMC Med. 2017 Sep 18;15(1):172. doi: 10.1186/s12916-017-0930-5.

43.

Pharmacokinetic/Toxicodynamic Analysis of Colistin-Associated Acute Kidney Injury in Critically Ill Patients.

Forrest A, Garonzik SM, Thamlikitkul V, Giamarellos-Bourboulis EJ, Paterson DL, Li J, Silveira FP, Nation RL.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01367-17. doi: 10.1128/AAC.01367-17. Print 2017 Nov.

44.

Management of KPC-producing Klebsiella pneumoniae infections.

Bassetti M, Giacobbe DR, Giamarellou H, Viscoli C, Daikos GL, Dimopoulos G, De Rosa FG, Giamarellos-Bourboulis EJ, Rossolini GM, Righi E, Karaiskos I, Tumbarello M, Nicolau DP, Viale PL, Poulakou G; Critically Ill Patients Study Group of the European Society of Clinical Microbiology and Infectious Disease (ESCMID); Hellenic Society of Chemotherapy (HSC) and Società Italiana di Terapia Antinfettiva (SITA).

Clin Microbiol Infect. 2018 Feb;24(2):133-144. doi: 10.1016/j.cmi.2017.08.030. Epub 2017 Sep 9. Review.

45.

Is small intestinal bacterial overgrowth involved in the pathogenesis of functional dyspepsia?

Tziatzios G, Giamarellos-Bourboulis EJ, Papanikolaou IS, Pimentel M, Dimitriadis GD, Triantafyllou K.

Med Hypotheses. 2017 Sep;106:26-32. doi: 10.1016/j.mehy.2017.07.005. Epub 2017 Jul 6.

PMID:
28818267
46.

The Statistical Significance of the Efficacy Results in a Randomized Clinical Trial-Reply.

Giamarellos-Bourboulis EJ.

JAMA Dermatol. 2017 Sep 1;153(9):950. doi: 10.1001/jamadermatol.2017.3244. No abstract available.

PMID:
28793159
47.

A guiding map for inflammation.

Netea MG, Balkwill F, Chonchol M, Cominelli F, Donath MY, Giamarellos-Bourboulis EJ, Golenbock D, Gresnigt MS, Heneka MT, Hoffman HM, Hotchkiss R, Joosten LAB, Kastner DL, Korte M, Latz E, Libby P, Mandrup-Poulsen T, Mantovani A, Mills KHG, Nowak KL, O'Neill LA, Pickkers P, van der Poll T, Ridker PM, Schalkwijk J, Schwartz DA, Siegmund B, Steer CJ, Tilg H, van der Meer JWM, van de Veerdonk FL, Dinarello CA.

Nat Immunol. 2017 Jul 19;18(8):826-831. doi: 10.1038/ni.3790.

48.

Lipid peroxidation in Gram-negative bacteremia modulates the risk for septic shock and infections by resistant Klebsiella pneumoniae.

Christodoulou S, Kyriazopoulou E, Chrysanthakopoulou M, Karlis G, Karampela I, Gkizeli K, Veliki N, Safarika A, Giamarellos-Bourboulis EJ, Adamis G; Hellenic Sepsis Study Group.

Eur J Clin Microbiol Infect Dis. 2017 Nov;36(11):2171-2177. doi: 10.1007/s10096-017-3041-5. Epub 2017 Jun 21.

PMID:
28639164
49.

Development and validation of the International Hidradenitis Suppurativa Severity Score System (IHS4), a novel dynamic scoring system to assess HS severity.

Zouboulis CC, Tzellos T, Kyrgidis A, Jemec GBE, Bechara FG, Giamarellos-Bourboulis EJ, Ingram JR, Kanni T, Karagiannidis I, Martorell A, Matusiak Ł, Pinter A, Prens EP, Presser D, Schneider-Burrus S, von Stebut E, Szepietowski JC, van der Zee HH, Wilden SM, Sabat R; European Hidradenitis Suppurativa Foundation Investigator Group.

Br J Dermatol. 2017 Nov;177(5):1401-1409. doi: 10.1111/bjd.15748. Epub 2017 Oct 30.

PMID:
28636793
50.

Efficacy of intramuscular moxifloxacin in the treatment of experimental osteomyelitis caused by methicillin-resistant Staphylococcus aureus.

Soranoglou V, Galanopoulos I, Giamarellos-Bourboulis EJ, Papalois A, Giannitsioti E, Poultsides LA, Choreftaki T, Kanellakopoulou K.

Int J Antimicrob Agents. 2017 Aug;50(2):186-190. doi: 10.1016/j.ijantimicag.2017.01.041. Epub 2017 Jun 1.

PMID:
28579454

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