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Items: 1 to 50 of 69

1.

Could dissecting the molecular framework of β-lactam integrin ligands enhance selectivity?

Martelli G, Baiula M, Caligiana A, Galletti P, Gentilucci L, Artali R, Spampinato SM, Giacomini D.

J Med Chem. 2019 Oct 31. doi: 10.1021/acs.jmedchem.9b01000. [Epub ahead of print]

PMID:
31670514
2.

Resistance to clethodim in Italian ryegrass (Lolium perenne ssp. multiflorum) from Mississippi and North Carolina.

Nandula VK, Giacomini DA, Lawrence BH, Molin WT, Bond JA.

Pest Manag Sci. 2019 Oct 15. doi: 10.1002/ps.5650. [Epub ahead of print]

PMID:
31613044
3.

Winter-Season Gaseous Nitrogen Emissions in Subtropical Climate: Impacts of Pig Slurry Injection and Nitrification Inhibitor.

Aita C, Chantigny MH, Gonzatto R, Miola ECC, Rochette P, Pujol SB, Dos Santos DB, Giacomini DA, Giacomini SJ.

J Environ Qual. 2019 Sep;48(5):1414-1426. doi: 10.2134/jeq2018.04.0137.

PMID:
31589701
4.

Multiple modes of convergent adaptation in the spread of glyphosate-resistant Amaranthus tuberculatus.

Kreiner JM, Giacomini DA, Bemm F, Waithaka B, Regalado J, Lanz C, Hildebrandt J, Sikkema PH, Tranel PJ, Weigel D, Stinchcombe JR, Wright SI.

Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21076-21084. doi: 10.1073/pnas.1900870116. Epub 2019 Sep 30. Erratum in: Proc Natl Acad Sci U S A. 2019 Nov 4;:.

5.

Activity-Dependent Reconnection of Adult-Born Dentate Granule Cells in a Mouse Model of Frontotemporal Dementia.

Terreros-Roncal J, Flor-García M, Moreno-Jiménez EP, Pallas-Bazarra N, Rábano A, Sah N, van Praag H, Giacomini D, Schinder AF, Ávila J, Llorens-Martín M.

J Neurosci. 2019 Jul 17;39(29):5794-5815. doi: 10.1523/JNEUROSCI.2724-18.2019. Epub 2019 May 27.

PMID:
31133559
6.

Chiral β-lactam-based integrin ligands through Lipase-catalysed kinetic resolution and their enantioselective receptor response.

Martelli G, Galletti P, Baiula M, Calcinari L, Boschi G, Giacomini D.

Bioorg Chem. 2019 Jul;88:102975. doi: 10.1016/j.bioorg.2019.102975. Epub 2019 May 9.

PMID:
31102807
7.

Antibacterial and antioxidant activities for natural and synthetic dual-active compounds.

Martelli G, Giacomini D.

Eur J Med Chem. 2018 Oct 5;158:91-105. doi: 10.1016/j.ejmech.2018.09.009. Epub 2018 Sep 5. Review.

PMID:
30205261
8.

Population Genetic Structure in Glyphosate-Resistant and -Susceptible Palmer Amaranth (Amaranthus palmeri) Populations Using Genotyping-by-sequencing (GBS).

Küpper A, Manmathan HK, Giacomini D, Patterson EL, McCloskey WB, Gaines TA.

Front Plant Sci. 2018 Jan 25;9:29. doi: 10.3389/fpls.2018.00029. eCollection 2018.

9.

Optimizing RNA-seq studies to investigate herbicide resistance.

Giacomini DA, Gaines T, Beffa R, Tranel PJ.

Pest Manag Sci. 2018 Oct;74(10):2260-2264. doi: 10.1002/ps.4822. Epub 2018 Feb 16. Review.

PMID:
29222921
10.

4-Alkyliden-azetidinones modified with plant derived polyphenols: Antibacterial and antioxidant properties.

Giacomini D, Musumeci R, Galletti P, Martelli G, Assennato L, Sacchetti G, Guerrini A, Calaresu E, Martinelli M, Cocuzza C.

Eur J Med Chem. 2017 Nov 10;140:604-614. doi: 10.1016/j.ejmech.2017.09.048. Epub 2017 Sep 23.

PMID:
28992569
11.

Design and Synthesis of 4-Alkylidene-β-lactams: Benzyl- and Phenethyl-carbamates as Key Fragments to Switch on Antibacterial Activity.

Giacomini D, Martelli G, Piccichè M, Calaresu E, Cocuzza CE, Musumeci R.

ChemMedChem. 2017 Sep 21;12(18):1525-1533. doi: 10.1002/cmdc.201700307. Epub 2017 Aug 31.

PMID:
28737008
12.

Can Integrin Agonists Have Cards to Play against Cancer? A Literature Survey of Small Molecules Integrin Activators.

Tolomelli A, Galletti P, Baiula M, Giacomini D.

Cancers (Basel). 2017 Jul 5;9(7). pii: E78. doi: 10.3390/cancers9070078. Review.

13.

Monocyclic β-lactams loaded on hydroxyapatite: new biomaterials with enhanced antibacterial activity against resistant strains.

Giacomini D, Torricelli P, Gentilomi GA, Boanini E, Gazzano M, Bonvicini F, Benetti E, Soldati R, Martelli G, Rubini K, Bigi A.

Sci Rep. 2017 Jun 2;7(1):2712. doi: 10.1038/s41598-017-02943-2.

14.

Two new PPX2 mutations associated with resistance to PPO-inhibiting herbicides in Amaranthus palmeri.

Giacomini DA, Umphres AM, Nie H, Mueller TC, Steckel LE, Young BG, Scott RC, Tranel PJ.

Pest Manag Sci. 2017 Aug;73(8):1559-1563. doi: 10.1002/ps.4581. Epub 2017 May 16.

PMID:
28370968
15.

A disynaptic feedback network activated by experience promotes the integration of new granule cells.

Alvarez DD, Giacomini D, Yang SM, Trinchero MF, Temprana SG, Büttner KA, Beltramone N, Schinder AF.

Science. 2016 Oct 28;354(6311):459-465. Epub 2016 Oct 27.

PMID:
27789840
16.

New β-Lactam Derivatives Modulate Cell Adhesion and Signaling Mediated by RGD-Binding and Leukocyte Integrins.

Baiula M, Galletti P, Martelli G, Soldati R, Belvisi L, Civera M, Dattoli SD, Spampinato SM, Giacomini D.

J Med Chem. 2016 Nov 10;59(21):9721-9742. Epub 2016 Oct 21.

17.

CT diagnosis of a coronary-pulmonary baffle leak complicating Takeuchi repair procedure for ALCAPA syndrome.

Giacomini D, Romanucci G, Savastano S.

J Cardiovasc Comput Tomogr. 2016 Mar-Apr;10(2):184-5. doi: 10.1016/j.jcct.2015.09.005. Epub 2015 Oct 9. No abstract available.

PMID:
26454424
18.

Injection of Dicyandiamide-Treated Pig Slurry Reduced Ammonia Volatilization without Enhancing Soil Nitrous Oxide Emissions from No-Till Corn in Southern Brazil.

Aita C, Gonzatto R, Miola EC, B D, Santos D, Rochette P, Angers DA, Chantigny MH, Pujol SB, Giacomini DA, Giacomini SJ.

J Environ Qual. 2014 May;43(3):789-800. doi: 10.2134/jeq2013.07.0301.

PMID:
25602808
19.

Delayed coupling to feedback inhibition during a critical period for the integration of adult-born granule cells.

Temprana SG, Mongiat LA, Yang SM, Trinchero MF, Alvarez DD, Kropff E, Giacomini D, Beltramone N, Lanuza GM, Schinder AF.

Neuron. 2015 Jan 7;85(1):116-130. doi: 10.1016/j.neuron.2014.11.023. Epub 2014 Dec 18.

20.

Gene amplification of 5-enol-pyruvylshikimate-3-phosphate synthase in glyphosate-resistant Kochia scoparia.

Wiersma AT, Gaines TA, Preston C, Hamilton JP, Giacomini D, Robin Buell C, Leach JE, Westra P.

Planta. 2015 Feb;241(2):463-74. doi: 10.1007/s00425-014-2197-9. Epub 2014 Nov 5.

PMID:
25366557
21.

CT, MRI and DWI Features of a Solid Organizing Hepatic Abscess.

Savastano S, Pellizzer G, Di Grazia L, Giacomini D, Beghetto M.

Case Rep Radiol. 2014;2014:930569. doi: 10.1155/2014/930569. Epub 2014 Aug 13.

22.

Laccase-mediator system for alcohol oxidation to carbonyls or carboxylic acids: toward a sustainable synthesis of profens.

Galletti P, Pori M, Funiciello F, Soldati R, Ballardini A, Giacomini D.

ChemSusChem. 2014 Sep;7(9):2684-9. doi: 10.1002/cssc.201402136. Epub 2014 Jul 13.

PMID:
25044433
23.

Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives.

Galletti P, Soldati R, Pori M, Durso M, Tolomelli A, Gentilucci L, Dattoli SD, Baiula M, Spampinato S, Giacomini D.

Eur J Med Chem. 2014 Aug 18;83:284-93. doi: 10.1016/j.ejmech.2014.06.041. Epub 2014 Jun 19.

PMID:
24973662
24.

Azetidinone-retinoid hybrids: synthesis and differentiative effects.

Pori M, Galletti P, Soldati R, Calzà L, Mangano C, Giacomini D.

Eur J Med Chem. 2013;70:857-63. doi: 10.1016/j.ejmech.2013.09.057. Epub 2013 Oct 12.

PMID:
24262378
25.

Abdominal aortic calcification is an independent predictor of cardiovascular events in peritoneal dialysis patients.

Martino F, Di Loreto P, Giacomini D, Kaushik M, Rodighiero MP, Crepaldi C, Ronco C.

Ther Apher Dial. 2013 Aug;17(4):448-53. doi: 10.1111/j.1744-9987.2012.01084.x. Epub 2012 Jun 19.

PMID:
23931888
26.

Delayed dendritic development in newly generated dentate granule cells by cell-autonomous expression of the amyloid precursor protein.

Morgenstern NA, Giacomini D, Lombardi G, Castaño EM, Schinder AF.

Mol Cell Neurosci. 2013 Sep;56:298-306. doi: 10.1016/j.mcn.2013.07.003. Epub 2013 Jul 11.

27.

Persistence and degradation of new β-lactam antibiotics in the soil and water environment.

Braschi I, Blasioli S, Fellet C, Lorenzini R, Garelli A, Pori M, Giacomini D.

Chemosphere. 2013 Sep;93(1):152-9. doi: 10.1016/j.chemosphere.2013.05.016. Epub 2013 Jun 15.

PMID:
23777677
28.

B-Raf and CRHR1 internalization mediate biphasic ERK1/2 activation by CRH in hippocampal HT22 Cells.

Bonfiglio JJ, Inda C, Senin S, Maccarrone G, Refojo D, Giacomini D, Turck CW, Holsboer F, Arzt E, Silberstein S.

Mol Endocrinol. 2013 Mar;27(3):491-510. doi: 10.1210/me.2012-1359. Epub 2013 Jan 31.

29.

Monocyclic β-lactams as antibacterial agents: facing antioxidant activity of N-methylthio-azetidinones.

Cervellati R, Galletti P, Greco E, Cocuzza CE, Musumeci R, Bardini L, Paolucci F, Pori M, Soldati R, Giacomini D.

Eur J Med Chem. 2013 Feb;60:340-9. doi: 10.1016/j.ejmech.2012.12.024. Epub 2012 Dec 20.

PMID:
23314047
30.

Monocyclic β-lactams: new structures for new biological activities.

Galletti P, Giacomini D.

Curr Med Chem. 2011;18(28):4265-83. Review.

PMID:
21861821
31.

Antibacterial agents and cystic fibrosis: synthesis and antimicrobial evaluation of a series of N-thiomethylazetidinones.

Galletti P, Cocuzza CE, Pori M, Quintavalla A, Musumeci R, Giacomini D.

ChemMedChem. 2011 Oct 4;6(10):1919-27. doi: 10.1002/cmdc.201100282. Epub 2011 Aug 10.

PMID:
21834093
32.

Chemoenzymatic synthesis of (2S)-2-arylpropanols through a dynamic kinetic resolution of 2-arylpropanals with alcohol dehydrogenases.

Galletti P, Emer E, Gucciardo G, Quintavalla A, Pori M, Giacomini D.

Org Biomol Chem. 2010 Sep 21;8(18):4117-23. doi: 10.1039/c005098a. Epub 2010 Jul 13.

PMID:
20625608
33.

Cytokines and genes in pituitary tumorigenesis: RSUME role in cell biology.

Fuertes M, Gerez J, Haedo M, Giacomini D, Páez-Pereda M, Labeur M, Stalla GK, Arzt E.

Front Horm Res. 2010;38:1-6. doi: 10.1159/000318488. Epub 2010 Jul 5. Review.

PMID:
20616489
34.

Morphometric analysis of the canal system of cortical bone: An experimental study in the rabbit femur carried out with standard histology and micro-CT.

Pazzaglia UE, Zarattini G, Giacomini D, Rodella L, Menti AM, Feltrin G.

Anat Histol Embryol. 2010 Feb;39(1):17-26. doi: 10.1111/j.1439-0264.2009.00973.x. Epub 2009 Oct 28.

PMID:
19874276
35.

Regulation of pituitary function by cytokines.

Haedo MR, Gerez J, Fuertes M, Giacomini D, Páez-Pereda M, Labeur M, Renner U, Stalla GK, Arzt E.

Horm Res. 2009;72(5):266-74. doi: 10.1159/000245928. Epub 2009 Oct 19. Review.

36.

Azetidinones as zinc-binding groups to design selective HDAC8 inhibitors.

Galletti P, Quintavalla A, Ventrici C, Giannini G, Cabri W, Penco S, Gallo G, Vincenti S, Giacomini D.

ChemMedChem. 2009 Dec;4(12):1991-2001. doi: 10.1002/cmdc.200900309.

PMID:
19821480
37.

Solvent effects on stereoselectivity: more than just an environment.

Cainelli G, Galletti P, Giacomini D.

Chem Soc Rev. 2009 Apr;38(4):990-1001. doi: 10.1039/b802815j. Epub 2009 Feb 12.

PMID:
19421577
38.

Differential gene expression in models of pituitary prolactin-producing tumoral cells.

Giacomini D, Haedo M, Gerez J, Druker J, Páez-Pereda M, Labeur M, Stalla GK, Arzt E.

Horm Res. 2009 Apr;71 Suppl 2:88-94. doi: 10.1159/000192444. Epub 2009 Apr 29. Review.

PMID:
19407504
39.

Molecular interaction of BMP-4, TGF-beta, and estrogens in lactotrophs: impact on the PRL promoter.

Giacomini D, Páez-Pereda M, Stalla J, Stalla GK, Arzt E.

Mol Endocrinol. 2009 Jul;23(7):1102-14. doi: 10.1210/me.2008-0425. Epub 2009 Apr 2.

40.

New polyphenolic beta-lactams with antioxidant activity.

Cainelli G, Angeloni C, Cervellati R, Galletti P, Giacomini D, Hrelia S, Sinisi R.

Chem Biodivers. 2008 May;5(5):811-29. doi: 10.1002/cbdv.200890077.

PMID:
18493967
41.

Highly efficient asymmetric reduction of arylpropionic aldehydes by horse liver alcohol dehydrogenase through dynamic kinetic resolution.

Giacomini D, Galletti P, Quintavalla A, Gucciardo G, Paradisi F.

Chem Commun (Camb). 2007 Oct 21;(39):4038-40. Epub 2007 Sep 10.

PMID:
17912408
42.

Molecular transduction mechanisms of cytokine-hormone interactions: role of gp130 cytokines.

Gerez J, Bonfiglio J, Sosa S, Giacomini D, Acuña M, Nagashima AC, Perone MJ, Silberstein S, Renner U, Stalla GK, Arzt E.

Exp Physiol. 2007 Sep;92(5):801-6. Review.

43.

Inhibitory effect by new monocyclic 4-alkyliden-beta-lactam compounds on human platelet activation.

Pavanetto M, Zarpellon A, Giacomini D, Galletti P, Quintavalla A, Cainelli G, Folda A, Scutari G, Deana R.

Platelets. 2007 Aug;18(5):357-64.

PMID:
17654305
44.

Pituitary action of cytokines: focus on BMP-4 and gp130 family.

Giacomini D, Acuña M, Gerez J, Nagashima AC, Silberstein S, Páez-Pereda M, Labeur M, Theodoropoulou M, Renner U, Stalla GK, Arzt E.

Neuroendocrinology. 2007;85(2):94-100. Epub 2007 Feb 28. Review.

PMID:
17337883
45.

Molecular understanding of cytokine-steroid hormone dialogue: implications for human diseases.

Druker J, Liberman AC, Acuña M, Giacomini D, Refojo D, Silberstein S, Pereda MP, Stalla GK, Holsboer F, Arzt E.

Ann N Y Acad Sci. 2006 Nov;1088:297-306. Review.

PMID:
17192575
46.

Bone morphogenetic protein-4 control of pituitary pathophysiology.

Giacomini D, Páez-Pereda M, Theodoropoulou M, Gerez J, Nagashima AC, Chervin A, Berner S, Labeur M, Refojo D, Renner U, Stalla GK, Arzt E.

Front Horm Res. 2006;35:22-31. doi: 10.1159/000094262. Review.

PMID:
16809920
47.

Retinoic acid as a novel medical therapy for Cushing's disease in dogs.

Castillo V, Giacomini D, Páez-Pereda M, Stalla J, Labeur M, Theodoropoulou M, Holsboer F, Grossman AB, Stalla GK, Arzt E.

Endocrinology. 2006 Sep;147(9):4438-44. Epub 2006 Jun 1.

PMID:
16740975
48.

Design, synthesis, and biological evaluation of 4-alkyliden-beta lactams: new products with promising antibiotic activity against resistant bacteria.

Broccolo F, Cainelli G, Caltabiano G, Cocuzza CE, Fortuna CG, Galletti P, Giacomini D, Musumarra G, Musumeci R, Quintavalla A.

J Med Chem. 2006 May 4;49(9):2804-11.

PMID:
16640341
49.

Engineered phenylalanine dehydrogenase in organic solvents: homogeneous and biphasic enzymatic reactions.

Cainelli G, Engel PC, Galletti P, Giacomini D, Gualandi A, Paradisi F.

Org Biomol Chem. 2005 Dec 21;3(24):4316-20. Epub 2005 Nov 14.

PMID:
16327891
50.

Inhibition of leukocyte elastase, polymorphonuclear chemoinvasion, and inflammation-triggered pulmonary fibrosis by a 4-alkyliden-beta-lactam with a galloyl moiety.

Dell'Aica I, Sartor L, Galletti P, Giacomini D, Quintavalla A, Calabrese F, Giacometti C, Brunetta E, Piazza F, Agostini C, Garbisa S.

J Pharmacol Exp Ther. 2006 Feb;316(2):539-46. Epub 2005 Oct 25.

PMID:
16249367

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