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Conformational characterization of full-length X-chromosome-linked inhibitor of apoptosis protein (XIAP) through an integrated approach.

Polykretis P, Luchinat E, Bonucci A, Giachetti A, Graewert MA, Svergun DI, Banci L.

IUCrJ. 2019 Aug 23;6(Pt 5):948-957. doi: 10.1107/S205225251901073X. eCollection 2019 Sep 1.


An atomistic view of the YiiP structural changes upon zinc(II) binding.

Sala D, Giachetti A, Rosato A.

Biochim Biophys Acta Gen Subj. 2019 Oct;1863(10):1560-1567. doi: 10.1016/j.bbagen.2019.06.001. Epub 2019 Jun 6.


Targeting endothelial-to-mesenchymal transition: the protective role of hydroxytyrosol sulfate metabolite.

Terzuoli E, Nannelli G, Giachetti A, Morbidelli L, Ziche M, Donnini S.

Eur J Nutr. 2019 Feb 6. doi: 10.1007/s00394-019-01920-x. [Epub ahead of print]


Correction to: Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1α/VEGF signalling in MCF-7 breast cancer cells.

Ciccone V, Terzuoli E, Donnini S, Giachetti A, Morbidelli L, Ziche M.

J Exp Clin Cancer Res. 2019 Feb 1;38(1):45. doi: 10.1186/s13046-019-1045-y.


Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1α/VEGF signalling in MCF-7 breast cancer cells.

Ciccone V, Terzuoli E, Donnini S, Giachetti A, Morbidelli L, Ziche M.

J Exp Clin Cancer Res. 2018 Dec 12;37(1):311. doi: 10.1186/s13046-018-0975-0. Erratum in: J Exp Clin Cancer Res. 2019 Feb 1;38(1):45.


ALDH2 Activity Reduces Mitochondrial Oxygen Reserve Capacity in Endothelial Cells and Induces Senescence Properties.

Nannelli G, Terzuoli E, Giorgio V, Donnini S, Lupetti P, Giachetti A, Bernardi P, Ziche M.

Oxid Med Cell Longev. 2018 Nov 14;2018:9765027. doi: 10.1155/2018/9765027. eCollection 2018.


Bradykinin B2 Receptor Contributes to Inflammatory Responses in Human Endothelial Cells by the Transactivation of the Fibroblast Growth Factor Receptor FGFR-1.

Terzuoli E, Corti F, Nannelli G, Giachetti A, Donnini S, Ziche M.

Int J Mol Sci. 2018 Sep 6;19(9). pii: E2638. doi: 10.3390/ijms19092638.


PGE2 mediates EGFR internalization and nuclear translocation via caveolin endocytosis promoting its transcriptional activity and proliferation in human NSCLC cells.

Bazzani L, Donnini S, Giachetti A, Christofori G, Ziche M.

Oncotarget. 2018 Feb 15;9(19):14939-14958. doi: 10.18632/oncotarget.24499. eCollection 2018 Mar 13.


Involvement of Bradykinin B2 Receptor in Pathological Vascularization in Oxygen-Induced Retinopathy in Mice and Rabbit Cornea.

Terzuoli E, Morbidelli L, Nannelli G, Giachetti A, Donnini S, Ziche M.

Int J Mol Sci. 2018 Jan 23;19(2). pii: E330. doi: 10.3390/ijms19020330.


Inhibition of cell cycle progression by the hydroxytyrosol-cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells.

Terzuoli E, Nannelli G, Frosini M, Giachetti A, Ziche M, Donnini S.

Oncotarget. 2017 Aug 24;8(47):83207-83224. doi: 10.18632/oncotarget.20544. eCollection 2017 Oct 10.


Investigation of the Iron(II) Release Mechanism of Human H-Ferritin as a Function of pH.

Sala D, Ciambellotti S, Giachetti A, Turano P, Rosato A.

J Chem Inf Model. 2017 Sep 25;57(9):2112-2118. doi: 10.1021/acs.jcim.7b00306. Epub 2017 Sep 12.


Structural insights into the molecular function of human [2Fe-2S] BOLA1-GRX5 and [2Fe-2S] BOLA3-GRX5 complexes.

Nasta V, Giachetti A, Ciofi-Baffoni S, Banci L.

Biochim Biophys Acta Gen Subj. 2017 Aug;1861(8):2119-2131. doi: 10.1016/j.bbagen.2017.05.005. Epub 2017 May 5.


Linking of mPGES-1 and iNOS activates stem-like phenotype in EGFR-driven epithelial tumor cells.

Terzuoli E, Finetti F, Costanza F, Giachetti A, Ziche M, Donnini S.

Nitric Oxide. 2017 Jun 1;66:17-29. doi: 10.1016/j.niox.2017.02.010. Epub 2017 Mar 1.


A protocol for the refinement of NMR structures using simultaneously pseudocontact shift restraints from multiple lanthanide ions.

Sala D, Giachetti A, Luchinat C, Rosato A.

J Biomol NMR. 2016 Nov;66(3):175-185. Epub 2016 Oct 22.


Linking microsomal prostaglandin E Synthase-1/PGE-2 pathway with miR-15a and -186 expression: Novel mechanism of VEGF modulation in prostate cancer.

Terzuoli E, Donnini S, Finetti F, Nesi G, Villari D, Hanaka H, Radmark O, Giachetti A, Ziche M.

Oncotarget. 2016 Jul 12;7(28):44350-44364. doi: 10.18632/oncotarget.10051.


Hydroxytyrosol, a product from olive oil, reduces colon cancer growth by enhancing epidermal growth factor receptor degradation.

Terzuoli E, Giachetti A, Ziche M, Donnini S.

Mol Nutr Food Res. 2016 Mar;60(3):519-29. doi: 10.1002/mnfr.201500498. Epub 2015 Dec 17.


Scale Space Graph Representation and Kernel Matching for Non Rigid and Textured 3D Shape Retrieval.

Garro V, Giachetti A.

IEEE Trans Pattern Anal Mach Intell. 2016 Jun;38(6):1258-71. doi: 10.1109/TPAMI.2015.2477823. Epub 2015 Sep 10.


Accurate and reliable segmentation of the optic disc in digital fundus images.

Giachetti A, Ballerini L, Trucco E.

J Med Imaging (Bellingham). 2014 Jul;1(2):024001. doi: 10.1117/1.JMI.1.2.024001. Epub 2014 Jul 14.


mPGES-1 in prostate cancer controls stemness and amplifies epidermal growth factor receptor-driven oncogenicity.

Finetti F, Terzuoli E, Giachetti A, Santi R, Villari D, Hanaka H, Radmark O, Ziche M, Donnini S.

Endocr Relat Cancer. 2015 Aug;22(4):665-78. doi: 10.1530/ERC-15-0277. Epub 2015 Jun 25.


G-triplex structure and formation propensity.

Cerofolini L, Amato J, Giachetti A, Limongelli V, Novellino E, Parrinello M, Fragai M, Randazzo A, Luchinat C.

Nucleic Acids Res. 2014 Dec 1;42(21):13393-404. doi: 10.1093/nar/gku1084. Epub 2014 Nov 6.


Long-range correlated dynamics in intrinsically disordered proteins.

Parigi G, Rezaei-Ghaleh N, Giachetti A, Becker S, Fernandez C, Blackledge M, Griesinger C, Zweckstetter M, Luchinat C.

J Am Chem Soc. 2014 Nov 19;136(46):16201-9. doi: 10.1021/ja506820r. Epub 2014 Nov 4.


Infantile hemangioma or kaposiform hemangioendothelioma?

Garcia-Monaco RD, Giachetti A.

J Vasc Interv Radiol. 2014 May;25(5):810. doi: 10.1016/j.jvir.2014.01.024. No abstract available.


Robust automatic measurement of 3D scanned models for the human body fat estimation.

Giachetti A, Lovato C, Piscitelli F, Milanese C, Zancanaro C.

IEEE J Biomed Health Inform. 2015 Mar;19(2):660-7. doi: 10.1109/JBHI.2014.2314360. Epub 2014 Mar 28.


[Skin and soft tissue infections in children: consensus on diagnosis and treatment].

Comité Nacional de Infectología, Moyano M, Peuchot A, Giachetti AC, Moreno R, Cancellara A, Falaschi A, Chiarelli G, Villasboas RM, Corazza R, Magneres C, Calvari M, Roldán D.

Arch Argent Pediatr. 2014 Apr;112(2):183-91. doi: 10.1590/S0325-00752014000200019. Spanish.


Antagonism of bradykinin B2 receptor prevents inflammatory responses in human endothelial cells by quenching the NF-kB pathway activation.

Terzuoli E, Meini S, Cucchi P, Catalani C, Cialdai C, Maggi CA, Giachetti A, Ziche M, Donnini S.

PLoS One. 2014 Jan 2;9(1):e84358. doi: 10.1371/journal.pone.0084358. eCollection 2014.


Long-term treatment with oral propranolol reduces relapses of infantile hemangiomas.

Giachetti A, Garcia-Monaco R, Sojo M, Scacchi MF, Cernadas C, Guerchicoff Lemcke M, Dovasio F.

Pediatr Dermatol. 2014 Jan-Feb;31(1):14-20. doi: 10.1111/pde.12239. Epub 2013 Nov 27.


[Congenital cutaneous candidiasis].

Sket KV, Giachetti A, Sojo M, Garrido D, Lupo E, Brener P.

Arch Argent Pediatr. 2013 Dec;111(6):556-8. doi: 10.1590/S0325-00752013000600022. Spanish. No abstract available.


[Infantile hemangiomas].

Giachetti A, Sojo MM, García-Mónaco R.

Arch Argent Pediatr. 2013 Dec;111(6):537-45. doi: 10.1590/S0325-00752013000600014. Review. Spanish.


Cytochrome c and superoxide: a reply.

Wegerich F, Giachetti A, Allegrozzi M, Lisdat F, Turano P.

J Biol Inorg Chem. 2013 Oct;18(7):867-9. doi: 10.1007/s00775-013-1026-0. Epub 2013 Aug 11.


The use of radial symmetry to localize retinal landmarks.

Giachetti A, Ballerini L, Trucco E, Wilson PJ.

Comput Med Imaging Graph. 2013 Jul-Sep;37(5-6):369-76. doi: 10.1016/j.compmedimag.2013.06.005. Epub 2013 Jul 22.


PKCε activation promotes FGF-2 exocytosis and induces endothelial cell proliferation and sprouting.

Monti M, Donnini S, Morbidelli L, Giachetti A, Mochly-Rosen D, Mignatti P, Ziche M.

J Mol Cell Cardiol. 2013 Oct;63:107-17. doi: 10.1016/j.yjmcc.2013.07.006. Epub 2013 Jul 20.


Molecular view of an electron transfer process essential for iron-sulfur protein biogenesis.

Banci L, Bertini I, Calderone V, Ciofi-Baffoni S, Giachetti A, Jaiswal D, Mikolajczyk M, Piccioli M, Winkelmann J.

Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7136-41. doi: 10.1073/pnas.1302378110. Epub 2013 Apr 17.


Mechanistic insights into the superoxide-cytochrome c reaction by lysine surface scanning.

Wegerich F, Giachetti A, Allegrozzi M, Lisdat F, Turano P.

J Biol Inorg Chem. 2013 Apr;18(4):429-40. doi: 10.1007/s00775-013-0987-3. Epub 2013 Mar 3.


Mitochondrial aldehyde dehydrogenase-2 activation prevents β-amyloid-induced endothelial cell dysfunction and restores angiogenesis.

Solito R, Corti F, Chen CH, Mochly-Rosen D, Giachetti A, Ziche M, Donnini S.

J Cell Sci. 2013 May 1;126(Pt 9):1952-61. doi: 10.1242/jcs.117184. Epub 2013 Feb 27.


[Toxic epidermal necrolysis associated with acute infection by Mycoplasma pneumoniae].

Calvano RA, Scacchi MF, Sojo MM, Díaz SM, Volonteri VI, Giachetti AC.

Arch Argent Pediatr. 2013 Jan-Feb;111(1):e24-7. doi: 10.5546/aap.2013.e24. Spanish.


[Tinea faciei].

Gioseffi ML, Calvano R, Giachetti A, Sojo M.

Arch Argent Pediatr. 2013 Jan-Feb;111(1):74-6. doi: 10.5546/aap.2013.74. Spanish. No abstract available.


Assessing vascular senescence in zebrafish.

Donnini S, Giachetti A, Ziche M.

Methods Mol Biol. 2013;965:517-31. doi: 10.1007/978-1-62703-239-1_34.


Pharmacological inhibition of microsomal prostaglandin E synthase-1 suppresses epidermal growth factor receptor-mediated tumor growth and angiogenesis.

Finetti F, Terzuoli E, Bocci E, Coletta I, Polenzani L, Mangano G, Alisi MA, Cazzolla N, Giachetti A, Ziche M, Donnini S.

PLoS One. 2012;7(7):e40576. doi: 10.1371/journal.pone.0040576. Epub 2012 Jul 18.


Kaposiform hemangioendothelioma with Kasabach-Merritt phenomenon: successful treatment with embolization and vincristine in two newborns.

Garcia-Monaco R, Giachetti A, Peralta O, Napoli N, Lobos P, Gioseffi L, Mariani G.

J Vasc Interv Radiol. 2012 Mar;23(3):417-22. doi: 10.1016/j.jvir.2011.12.007.


Blind testing of routine, fully automated determination of protein structures from NMR data.

Rosato A, Aramini JM, Arrowsmith C, Bagaria A, Baker D, Cavalli A, Doreleijers JF, Eletsky A, Giachetti A, Guerry P, Gutmanas A, Güntert P, He Y, Herrmann T, Huang YJ, Jaravine V, Jonker HR, Kennedy MA, Lange OF, Liu G, Malliavin TE, Mani R, Mao B, Montelione GT, Nilges M, Rossi P, van der Schot G, Schwalbe H, Szyperski TA, Vendruscolo M, Vernon R, Vranken WF, Vries Sd, Vuister GW, Wu B, Yang Y, Bonvin AM.

Structure. 2012 Feb 8;20(2):227-36. doi: 10.1016/j.str.2012.01.002.


VAMPIRE: Vessel assessment and measurement platform for images of the REtina.

Perez-Rovira A, MacGillivray T, Trucco E, Chin KS, Zutis K, Lupascu C, Tegolo D, Giachetti A, Wilson PJ, Doney A, Dhillon B.

Conf Proc IEEE Eng Med Biol Soc. 2011;2011:3391-4. doi: 10.1109/IEMBS.2011.6090918.


EGFR signaling upregulates expression of microsomal prostaglandin E synthase-1 in cancer cells leading to enhanced tumorigenicity.

Donnini S, Finetti F, Terzuoli E, Giachetti A, Iñiguez MA, Hanaka H, Fresno M, Rådmark O, Ziche M.

Oncogene. 2012 Jul 19;31(29):3457-66. doi: 10.1038/onc.2011.503. Epub 2011 Nov 14.


Real-time artifact-free image upscaling.

Giachetti A, Asuni N.

IEEE Trans Image Process. 2011 Oct;20(10):2760-8. doi: 10.1109/TIP.2011.2136352. Erratum in: IEEE Trans Image Process. 2012 Apr;21(4):2361.


A Grid-enabled web portal for NMR structure refinement with AMBER.

Bertini I, Case DA, Ferella L, Giachetti A, Rosato A.

Bioinformatics. 2011 Sep 1;27(17):2384-90. doi: 10.1093/bioinformatics/btr415. Epub 2011 Jul 14.


Conformational space of flexible biological macromolecules from average data.

Bertini I, Giachetti A, Luchinat C, Parigi G, Petoukhov MV, Pierattelli R, Ravera E, Svergun DI.

J Am Chem Soc. 2010 Sep 29;132(38):13553-8. doi: 10.1021/ja1063923.


Inhibition of hypoxia inducible factor-1alpha by dihydroxyphenylethanol, a product from olive oil, blocks microsomal prostaglandin-E synthase-1/vascular endothelial growth factor expression and reduces tumor angiogenesis.

Terzuoli E, Donnini S, Giachetti A, Iñiguez MA, Fresno M, Melillo G, Ziche M.

Clin Cancer Res. 2010 Aug 15;16(16):4207-16. doi: 10.1158/1078-0432.CCR-10-0156. Epub 2010 Aug 3.


[Onichocryptosis in pediatrics: conservative treatment and spiculectomy].

Gioseffi ML, Giachetti A, Sánchez L, de Freijo S, Sojo M.

Arch Argent Pediatr. 2010 Jun;108(3):244-6. doi: 10.1590/S0325-00752010000300011. Spanish.


Abeta peptides accelerate the senescence of endothelial cells in vitro and in vivo, impairing angiogenesis.

Donnini S, Solito R, Cetti E, Corti F, Giachetti A, Carra S, Beltrame M, Cotelli F, Ziche M.

FASEB J. 2010 Jul;24(7):2385-95. doi: 10.1096/fj.09-146456. Epub 2010 Mar 5.


[Previous issue clinical case presentation: HSV infection (type 1)].

Gioseffi ML, Giachetti A, De Freijo S, Sojo M, Livellara B, Galli M, Leist M.

Arch Argent Pediatr. 2009 Dec;107(6):563-4. doi: 10.1590/S0325-00752009000600017. Spanish. No abstract available.


deltaPKC inhibition or varepsilonPKC activation repairs endothelial vascular dysfunction by regulating eNOS post-translational modification.

Monti M, Donnini S, Giachetti A, Mochly-Rosen D, Ziche M.

J Mol Cell Cardiol. 2010 Apr;48(4):746-56. doi: 10.1016/j.yjmcc.2009.11.002. Epub 2009 Nov 11.

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