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Items: 1 to 50 of 95

1.

Comparable efficacy with similarly low risk of hypoglycaemia in patient- vs physician-managed basal insulin initiation and titration in insulin-naïve type 2 diabetic subjects: the Italian Titration Approach Study (ITAS).

Bonadonna RC, Giaccari A, Buzzetti R, Perseghin G, Cucinotta D, Avogaro A, Aimaretti G, Larosa M, Fanelli CG, Bolli GB.

Diabetes Metab Res Rev. 2020 Mar 2:e3304. doi: 10.1002/dmrr.3304. [Epub ahead of print]

PMID:
32118347
2.

The Interplay between Immune System and Microbiota in Diabetes.

Moffa S, Mezza T, Cefalo CMA, Cinti F, Impronta F, Sorice GP, Santoro A, Di Giuseppe G, Pontecorvi A, Giaccari A.

Mediators Inflamm. 2019 Dec 30;2019:9367404. doi: 10.1155/2019/9367404. eCollection 2019. Review.

3.

Real-world outcomes of treatment with insulin glargine 300 U/mL versus standard-of-care in people with uncontrolled type 2 diabetes mellitus.

Freemantle N, Mauricio D, Giaccari A, Bailey T, Roussel R, Franco D, Berthou B, Pilorget V, Westerbacka J, Bosnyak Z, Bonnemaire M, Cali AMG, Nguyên-Pascal ML, Penfornis A, Perez-Maraver M, Seufert J, Sullivan SD, Wilding J, Wysham C, Davies M.

Curr Med Res Opin. 2020 Jan 19:1-11. doi: 10.1080/03007995.2019.1708287. [Epub ahead of print]

PMID:
31865758
4.

Postoperative hyperglycemia affects survival after gastrectomy for cancer: A single-center analysis using propensity score matching.

Fiorillo C, Quero G, Laterza V, Mascagni P, Longo F, Menghi R, Razionale F, Rosa F, Mezza T, Boskoski I, Giaccari A, Alfieri S.

Surgery. 2019 Dec 3. pii: S0039-6060(19)30742-1. doi: 10.1016/j.surg.2019.11.006. [Epub ahead of print]

PMID:
31810521
5.

Sotagliflozin Added to Optimized Insulin Therapy Leads to Lower Rates of Clinically Relevant Hypoglycemic Events at Any HbA1c at 52 Weeks in Adults with Type 1 Diabetes.

Danne T, Pettus J, Giaccari A, Cariou B, Rodbard H, Weinzimer SA, Bonnemaire M, Sawhney S, Stewart J, Wang S, Castro RC, Garg SK.

Diabetes Technol Ther. 2019 Sep;21(9):471-477. doi: 10.1089/dia.2019.0157.

6.

Corrigendum to "Italian Titration Approach Study (ITAS) with insulin glargine 300 U/mL in insulin-naïve type 2 diabetes: Design and population" [Nutr Metabol Cardiovasc Dis 29 (5) (May 2019) 496-503].

Bonadonna RC, Giaccari A, Buzzetti R, Aimaretti G, Cucinotta D, Avogaro A, Perseghin G, Larosa M, Bolli GB, Fanelli CG.

Nutr Metab Cardiovasc Dis. 2019 Aug;29(8):869-870. doi: 10.1016/j.numecd.2019.05.059. Epub 2019 Jun 27. No abstract available.

PMID:
31257093
7.

Sodium-glucose co-transporter inhibitors: Medications that mimic fasting for cardiovascular prevention.

Giaccari A.

Diabetes Obes Metab. 2019 Oct;21(10):2211-2218. doi: 10.1111/dom.13814. Epub 2019 Jul 5. Review.

PMID:
31209982
8.

β-Cell Fate in Human Insulin Resistance and Type 2 Diabetes: A Perspective on Islet Plasticity.

Mezza T, Cinti F, Cefalo CMA, Pontecorvi A, Kulkarni RN, Giaccari A.

Diabetes. 2019 Jun;68(6):1121-1129. doi: 10.2337/db18-0856. Review.

9.

Italian Titration Approach Study (ITAS) with insulin glargine 300 U/mL in insulin-naïve type 2 diabetes: Design and population.

Bonadonna RC, Giaccari A, Buzzetti R, Aimaretti G, Cucinotta D, Avogaro A, Perseghin G, Larosa M, Bolli GB, Fanelli CG.

Nutr Metab Cardiovasc Dis. 2019 May;29(5):496-503. doi: 10.1016/j.numecd.2019.01.011. Epub 2019 Feb 8. Erratum in: Nutr Metab Cardiovasc Dis. 2019 Aug;29(8):869-870.

PMID:
30952575
10.

Bile Modulates Secretion of Incretins and Insulin: A Study of Human Extrahepatic Cholestasis.

Mezza T, Moffa S, Ferraro PM, Quero G, Capece U, Carfì A, Cefalo CMA, Cinti F, Sorice GP, Impronta F, Mari A, Pontecorvi A, Alfieri S, Holst JJ, Giaccari A.

J Clin Endocrinol Metab. 2019 Jul 1;104(7):2685-2694. doi: 10.1210/jc.2018-02804.

PMID:
30874733
11.

Sotagliflozin, the first dual SGLT inhibitor: current outlook and perspectives.

Cefalo CMA, Cinti F, Moffa S, Impronta F, Sorice GP, Mezza T, Pontecorvi A, Giaccari A.

Cardiovasc Diabetol. 2019 Feb 28;18(1):20. doi: 10.1186/s12933-019-0828-y. Review.

12.

Increased β-Cell Workload Modulates Proinsulin-to-Insulin Ratio in Humans.

Mezza T, Ferraro PM, Sun VA, Moffa S, Cefalo CMA, Quero G, Cinti F, Sorice GP, Pontecorvi A, Folli F, Mari A, Alfieri S, Giaccari A.

Diabetes. 2018 Nov;67(11):2389-2396. doi: 10.2337/db18-0279. Epub 2018 Aug 21.

13.

Potential cause-effect relationship between insulin autoimmune syndrome and alpha lipoic acid: Two case reports.

Moffa S, Improta I, Rocchetti S, Mezza T, Giaccari A.

Nutrition. 2019 Jan;57:1-4. doi: 10.1016/j.nut.2018.04.010. Epub 2018 May 25.

PMID:
30086435
14.

Use and effectiveness of dapagliflozin in routine clinical practice: An Italian multicentre retrospective study.

Fadini GP, Zatti G, Baldi I, Bottigliengo D, Consoli A, Giaccari A, Sesti G, Avogaro A; DARWIN-T2D network.

Diabetes Obes Metab. 2018 Jul;20(7):1781-1786. doi: 10.1111/dom.13280. Epub 2018 Mar 30.

15.

Effect of Vitamin D Supplementation on Obesity-Induced Insulin Resistance: A Double-Blind, Randomized, Placebo-Controlled Trial.

Cefalo CMA, Conte C, Sorice GP, Moffa S, Sun VA, Cinti F, Salomone E, Muscogiuri G, Brocchi AAG, Pontecorvi A, Mezza T, Giaccari A.

Obesity (Silver Spring). 2018 Apr;26(4):651-657. doi: 10.1002/oby.22132. Epub 2018 Mar 4.

16.

Management of diabetes in older adults.

Sesti G, Antonelli Incalzi R, Bonora E, Consoli A, Giaccari A, Maggi S, Paolisso G, Purrello F, Vendemiale G, Ferrara N.

Nutr Metab Cardiovasc Dis. 2018 Mar;28(3):206-218. doi: 10.1016/j.numecd.2017.11.007. Epub 2017 Dec 7. Review.

17.

Publish and perish.

Giaccari A.

Nutr Metab Cardiovasc Dis. 2017 Dec;27(12):1035-1036. doi: 10.1016/j.numecd.2017.11.002. No abstract available.

PMID:
29198555
18.

FL-926-16, a novel bioavailable carnosinase-resistant carnosine derivative, prevents onset and stops progression of diabetic nephropathy in db/db mice.

Iacobini C, Menini S, Blasetti Fantauzzi C, Pesce CM, Giaccari A, Salomone E, Lapolla A, Orioli M, Aldini G, Pugliese G.

Br J Pharmacol. 2018 Jan;175(1):53-66. doi: 10.1111/bph.14070. Epub 2017 Dec 8.

19.

Spotlight on ertugliflozin and its potential in the treatment of type 2 diabetes: evidence to date.

Cinti F, Moffa S, Impronta F, Cefalo CM, Sun VA, Sorice GP, Mezza T, Giaccari A.

Drug Des Devel Ther. 2017 Oct 3;11:2905-2919. doi: 10.2147/DDDT.S114932. eCollection 2017. Review.

20.

Better glycaemic control and less hypoglycaemia with insulin glargine 300 U/mL vs glargine 100 U/mL: 1-year patient-level meta-analysis of the EDITION clinical studies in people with type 2 diabetes.

Ritzel R, Roussel R, Giaccari A, Vora J, Brulle-Wohlhueter C, Yki-Järvinen H.

Diabetes Obes Metab. 2018 Mar;20(3):541-548. doi: 10.1111/dom.13105. Epub 2017 Oct 5. Review.

21.

A consensus statement for the clinical use of the renal sodium-glucose co-transporter-2 inhibitor dapagliflozin in patients with type 2 diabetes mellitus.

Avogaro A, Giaccari A, Fioretto P, Genovese S, Purrello F, Giorgino F, Del Prato S.

Expert Rev Clin Pharmacol. 2017 Jul;10(7):763-772. doi: 10.1080/17512433.2017.1322507. Epub 2017 May 2. Review.

PMID:
28431476
22.

Nuclear Export of FoxO1 Is Associated with ERK Signaling in β-Cells Lacking Insulin Receptors.

Mezza T, Shirakawa J, Martinez R, Hu J, Giaccari A, Kulkarni RN.

J Biol Chem. 2016 Oct 7;291(41):21485-21495. Epub 2016 Aug 17.

23.

β-Cell Glucose Sensitivity Is Linked to Insulin/Glucagon Bihormonal Cells in Nondiabetic Humans.

Mezza T, Sorice GP, Conte C, Sun VA, Cefalo CM, Moffa S, Pontecorvi A, Mari A, Kulkarni RN, Giaccari A.

J Clin Endocrinol Metab. 2016 Feb;101(2):470-5. doi: 10.1210/jc.2015-2802. Epub 2015 Dec 9.

24.

Efficacy and safety of dapagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, in diabetes mellitus.

Fioretto P, Giaccari A, Sesti G.

Cardiovasc Diabetol. 2015 Oct 17;14:142. doi: 10.1186/s12933-015-0297-x. Review.

25.

Metabolic consequences of the occlusion of the main pancreatic duct with acrylic glue after pancreaticoduodenectomy.

Mezza T, Clemente G, Sorice GP, Conte C, De Rose AM, Sun VA, Cefalo CM, Pontecorvi A, Nuzzo G, Giaccari A.

Am J Surg. 2015 Oct;210(4):783-9. doi: 10.1016/j.amjsurg.2014.12.052. Epub 2015 Apr 30.

PMID:
26004536
26.

Welcome aboard.

Giaccari A.

Nutr Metab Cardiovasc Dis. 2015 Jan;25(1):1-2. doi: 10.1016/j.numecd.2014.12.003. No abstract available.

PMID:
25599990
27.

Peroxiredoxin 6, a novel player in the pathogenesis of diabetes.

Pacifici F, Arriga R, Sorice GP, Capuani B, Scioli MG, Pastore D, Donadel G, Bellia A, Caratelli S, Coppola A, Ferrelli F, Federici M, Sconocchia G, Tesauro M, Sbraccia P, Della-Morte D, Giaccari A, Orlandi A, Lauro D.

Diabetes. 2014 Oct;63(10):3210-20. doi: 10.2337/db14-0144. Epub 2014 Jun 19.

28.

HCC development is associated to peripheral insulin resistance in a mouse model of NASH.

De Minicis S, Agostinelli L, Rychlicki C, Sorice GP, Saccomanno S, Candelaresi C, Giaccari A, Trozzi L, Pierantonelli I, Mingarelli E, Marzioni M, Muscogiuri G, Gaggini M, Benedetti A, Gastaldelli A, Guido M, Svegliati-Baroni G.

PLoS One. 2014 May 22;9(5):e97136. doi: 10.1371/journal.pone.0097136. eCollection 2014.

29.

IL-21 is a major negative regulator of IRF4-dependent lipolysis affecting Tregs in adipose tissue and systemic insulin sensitivity.

Fabrizi M, Marchetti V, Mavilio M, Marino A, Casagrande V, Cavalera M, Moreno-Navarrete JM, Mezza T, Sorice GP, Fiorentino L, Menghini R, Lauro R, Monteleone G, Giaccari A, Fernandez Real JM, Federici M.

Diabetes. 2014 Jun;63(6):2086-96. doi: 10.2337/db13-0939. Epub 2014 Jan 15.

30.

Insulin resistance alters islet morphology in nondiabetic humans.

Mezza T, Muscogiuri G, Sorice GP, Clemente G, Hu J, Pontecorvi A, Holst JJ, Giaccari A, Kulkarni RN.

Diabetes. 2014 Mar;63(3):994-1007. doi: 10.2337/db13-1013. Epub 2013 Nov 11.

31.

Genetic disruption of SOD1 gene causes glucose intolerance and impairs β-cell function.

Muscogiuri G, Salmon AB, Aguayo-Mazzucato C, Li M, Balas B, Guardado-Mendoza R, Giaccari A, Reddick RL, Reyna SM, Weir G, Defronzo RA, Van Remmen H, Musi N.

Diabetes. 2013 Dec;62(12):4201-7. doi: 10.2337/db13-0314. Epub 2013 Sep 5.

32.

High-normal TSH values in obesity: is it insulin resistance or adipose tissue's guilt?

Muscogiuri G, Sorice GP, Mezza T, Prioletta A, Lassandro AP, Pirronti T, Della Casa S, Pontecorvi A, Giaccari A.

Obesity (Silver Spring). 2013 Jan;21(1):101-6. doi: 10.1002/oby.20240.

33.

A rare case of ectopic adrenocorticotropic hormone syndrome caused by a metastatic neuroendocrine tumor of the pancreas detected by 68Ga-DOTANOC and 18F-FDG PET/CT.

Treglia G, Salomone E, Petrone G, Giaccari A, Rindi G, Rufini V.

Clin Nucl Med. 2013 Jul;38(7):e306-8. doi: 10.1097/RLU.0b013e318279ec68.

PMID:
23486330
34.

Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus.

Kiechl S, Wittmann J, Giaccari A, Knoflach M, Willeit P, Bozec A, Moschen AR, Muscogiuri G, Sorice GP, Kireva T, Summerer M, Wirtz S, Luther J, Mielenz D, Billmeier U, Egger G, Mayr A, Oberhollenzer F, Kronenberg F, Orthofer M, Penninger JM, Meigs JB, Bonora E, Tilg H, Willeit J, Schett G.

Nat Med. 2013 Mar;19(3):358-63. doi: 10.1038/nm.3084. Epub 2013 Feb 10.

PMID:
23396210
35.

Removal of duodenum elicits GLP-1 secretion.

Muscogiuri G, Mezza T, Prioletta A, Sorice GP, Clemente G, Sarno G, Nuzzo G, Pontecorvi A, Holst JJ, Giaccari A.

Diabetes Care. 2013 Jun;36(6):1641-6. doi: 10.2337/dc12-0811. Epub 2013 Feb 7.

36.

Vitamin D deficiency: a new risk factor for type 2 diabetes?.

Mezza T, Muscogiuri G, Sorice GP, Prioletta A, Salomone E, Pontecorvi A, Giaccari A.

Ann Nutr Metab. 2012;61(4):337-48. doi: 10.1159/000342771. Epub 2012 Dec 3. Review.

37.

Early insulin treatment in type 2 diabetes: ORIGINal sin or valuable choice as ORIGINal treatment? An open debate on the ORIGIN study results.

Bolli GB, Consoli A, Giaccari A.

Nutr Metab Cardiovasc Dis. 2012 Dec;22(12):1007-12. doi: 10.1016/j.numecd.2012.10.004.

PMID:
23199612
38.
39.
40.

Metabolic syndrome in transplant patients: an updating point of view.

Sorice GP, Di Pizio L, Sun VA, Schirò T, Muscogiuri G, Mezza T, Cefalo CM, Prioletta A, Pontecorvi A, Giaccari A.

Minerva Endocrinol. 2012 Sep;37(3):211-20. Review.

PMID:
22766888
41.

Evaluation of guidelines on diabetes medication.

Giaccari A, Giorda CB, Riccardi G, De Micheli A, Bruno G, Monge L, Frontoni S.

Ann Intern Med. 2012 May 15;156(10):752-3; author reply 753. doi: 10.7326/0003-4819-156-10-201205150-00020. No abstract available.

PMID:
22586015
42.

Can vitamin D deficiency cause diabetes and cardiovascular diseases? Present evidence and future perspectives.

Muscogiuri G, Sorice GP, Ajjan R, Mezza T, Pilz S, Prioletta A, Scragg R, Volpe SL, Witham MD, Giaccari A.

Nutr Metab Cardiovasc Dis. 2012 Feb;22(2):81-7. doi: 10.1016/j.numecd.2011.11.001. Epub 2012 Jan 21. Review.

PMID:
22265795
43.

Low levels of 25(OH)D and insulin-resistance: 2 unrelated features or a cause-effect in PCOS?

Muscogiuri G, Policola C, Prioletta A, Sorice G, Mezza T, Lassandro A, Della Casa S, Pontecorvi A, Giaccari A.

Clin Nutr. 2012 Aug;31(4):476-80. doi: 10.1016/j.clnu.2011.12.010. Epub 2012 Jan 20.

PMID:
22260937
44.

D-Carnosine octylester attenuates atherosclerosis and renal disease in ApoE null mice fed a Western diet through reduction of carbonyl stress and inflammation.

Menini S, Iacobini C, Ricci C, Scipioni A, Blasetti Fantauzzi C, Giaccari A, Salomone E, Canevotti R, Lapolla A, Orioli M, Aldini G, Pugliese G.

Br J Pharmacol. 2012 Jun;166(4):1344-56. doi: 10.1111/j.1476-5381.2012.01834.x.

45.

The role of oxidative stress in the pathogenesis of type 2 diabetes mellitus micro- and macrovascular complications: avenues for a mechanistic-based therapeutic approach.

Folli F, Corradi D, Fanti P, Davalli A, Paez A, Giaccari A, Perego C, Muscogiuri G.

Curr Diabetes Rev. 2011 Sep;7(5):313-24. Review.

PMID:
21838680
46.

In anorexia nervosa, even a small increase in abdominal fat is responsible for the appearance of insulin resistance.

Prioletta A, Muscogiuri G, Sorice GP, Lassandro AP, Mezza T, Policola C, Salomone E, Cipolla C, Della Casa S, Pontecorvi A, Giaccari A.

Clin Endocrinol (Oxf). 2011 Aug;75(2):202-6. doi: 10.1111/j.1365-2265.2011.04046.x.

PMID:
21521315
47.

Single-fiber conduction velocity test allows earlier detection of abnormalities in diabetes.

Padua L, Stålberg E, Caliandro P, Muscogiuri G, Pazzaglia C, Sorice GP, Granata G, Salomone E, Pontecorvi A, Giaccari A.

Muscle Nerve. 2011 May;43(5):652-6. doi: 10.1002/mus.21935.

PMID:
21484824
48.

β-Adrenergic Responsive Induction of Insulin Resistance in Liver of Aging Rats.

Muscogiuri G, Kamat A, Balas B, Giaccari A, Defronzo RA, Musi N, Katz MS.

Endocr Res. 2011;36(2):74-82. doi: 10.3109/07435800.2010.539993. Epub 2011 Mar 26.

PMID:
21438725
49.

Metabolic syndrome in transplant patients: an academic or a health burden?

Sorice GP, Muscogiuri G, Mezza T, Prioletta A, Giaccari A.

Transplant Proc. 2011 Jan-Feb;43(1):313-7. doi: 10.1016/j.transproceed.2010.09.099.

PMID:
21335212
50.

Metabolic syndrome in subjects at high risk for type 2 diabetes: the genetic, physiopathology and evolution of type 2 diabetes (GENFIEV) study.

Bianchi C, Miccoli R, Bonadonna RC, Giorgino F, Frontoni S, Faloia E, Marchesini G, Dolci MA, Alviggi L, Gnasso A, Consoli A, Cavalot F, Cavallo MG, Leonetti F, Giaccari A, Del Prato S; GENFIEV Investigators.

Nutr Metab Cardiovasc Dis. 2011 Sep;21(9):699-705. doi: 10.1016/j.numecd.2010.03.006. Epub 2010 Nov 5.

PMID:
21291660

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