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Items: 1 to 50 of 350

1.

Functional screenings reveal different requirements for host microRNAs in Salmonella and Shigella infection.

Aguilar C, Cruz AR, Rodrigues Lopes I, Maudet C, Sunkavalli U, Silva RJ, Sharan M, Lisowski C, Zaldívar-López S, Garrido JJ, Giacca M, Mano M, Eulalio A.

Nat Microbiol. 2019 Dec 2. doi: 10.1038/s41564-019-0614-3. [Epub ahead of print]

PMID:
31792428
2.

Cardiac regeneration and remodelling of the cardiomyocyte cytoarchitecture.

Ali H, Braga L, Giacca M.

FEBS J. 2019 Nov 19. doi: 10.1111/febs.15146. [Epub ahead of print] Review.

PMID:
31743572
3.

miR-378a influences vascularization in skeletal muscles.

Krist B, Podkalicka P, Mucha O, Mendel M, Sępioł A, Rusiecka OM, Józefczuk E, Bukowska-Strakova K, Grochot-Przęczek A, Tomczyk M, Klóska D, Giacca M, Maga P, Niżankowski R, Józkowicz A, Łoboda A, Dulak J, Florczyk-Soluch U.

Cardiovasc Res. 2019 Aug 28. pii: cvz236. doi: 10.1093/cvr/cvz236. [Epub ahead of print]

PMID:
31504257
4.

Supporting data on in vitro cardioprotective and proliferative paracrine effects by the human amniotic fluid stem cell secretome.

Balbi C, Lodder K, Costa A, Moimas S, Moccia F, van Herwaarden T, Rosti V, Campagnoli F, Palmeri A, De Biasio P, Santini F, Giacca M, Goumans MJ, Barile L, Smits AM, Bollini S.

Data Brief. 2019 Jul 30;25:104324. doi: 10.1016/j.dib.2019.104324. eCollection 2019 Aug.

5.

mCerulean3-Based Cameleon Sensor to Explore Mitochondrial Ca2+ Dynamics In Vivo.

Greotti E, Fortunati I, Pendin D, Ferrante C, Galla L, Zentilin L, Giacca M, Kaludercic N, Di Sante M, Mariotti L, Lia A, Gómez-Gonzalo M, Sessolo M, Di Lisa F, Carmignoto G, Bozio R, Pozzan T.

iScience. 2019 Sep 27;19:161. doi: 10.1016/j.isci.2019.07.031. Epub 2019 Jul 30. No abstract available.

6.

High-content screen in human pluripotent cells identifies miRNA-regulated pathways controlling pluripotency and differentiation.

de Souza Lima IM, Schiavinato JLDS, Paulino Leite SB, Sastre D, Bezerra HLO, Sangiorgi B, Corveloni AC, Thomé CH, Faça VM, Covas DT, Zago MA, Giacca M, Mano M, Panepucci RA.

Stem Cell Res Ther. 2019 Jul 8;10(1):202. doi: 10.1186/s13287-019-1318-6.

7.

Sirt3 Deficiency Shortens Life Span and Impairs Cardiac Mitochondrial Function Rescued by Opa1 Gene Transfer.

Benigni A, Cassis P, Conti S, Perico L, Corna D, Cerullo D, Zentilin L, Zoja C, Perna A, Lionetti V, Giacca M, Trionfini P, Tomasoni S, Remuzzi G.

Antioxid Redox Signal. 2019 Dec;31(17):1255-1271. doi: 10.1089/ars.2018.7703. Epub 2019 Aug 2.

PMID:
31269804
8.

Coupling AAV-mediated promoterless gene targeting to SaCas9 nuclease to efficiently correct liver metabolic diseases.

De Caneva A, Porro F, Bortolussi G, Sola R, Lisjak M, Barzel A, Giacca M, Kay MA, Vlahoviček K, Zentilin L, Muro AF.

JCI Insight. 2019 Jun 18;5. pii: 128863. doi: 10.1172/jci.insight.128863.

9.

mCerulean3-Based Cameleon Sensor to Explore Mitochondrial Ca2+ Dynamics In Vivo.

Greotti E, Fortunati I, Pendin D, Ferrante C, Galla L, Zentilin L, Giacca M, Kaludercic N, Di Sante M, Mariotti L, Lia A, Gómez-Gonzalo M, Sessolo M, Di Lisa F, Carmignoto G, Bozio R, Pozzan T.

iScience. 2019 Jun 28;16:340-355. doi: 10.1016/j.isci.2019.05.031. Epub 2019 May 27. Erratum in: iScience. 2019 Sep 27;19:161.

10.

Renal Safety of Intravenous Ketorolac Use After Donor Nephrectomy.

Tabrizian P, Giacca M, Prigoff J, Tran B, Holzner ML, Chin E, Palese M, Herron D, Arvelakis A, Rudow DL, Florman S, Shapiro R.

Prog Transplant. 2019 Sep;29(3):283-286. doi: 10.1177/1526924819855360. Epub 2019 Jun 11.

PMID:
31185805
11.

Common Regulatory Pathways Mediate Activity of MicroRNAs Inducing Cardiomyocyte Proliferation.

Torrini C, Cubero RJ, Dirkx E, Braga L, Ali H, Prosdocimo G, Gutierrez MI, Collesi C, Licastro D, Zentilin L, Mano M, Zacchigna S, Vendruscolo M, Marsili M, Samal A, Giacca M.

Cell Rep. 2019 May 28;27(9):2759-2771.e5. doi: 10.1016/j.celrep.2019.05.005.

12.

MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs.

Gabisonia K, Prosdocimo G, Aquaro GD, Carlucci L, Zentilin L, Secco I, Ali H, Braga L, Gorgodze N, Bernini F, Burchielli S, Collesi C, Zandonà L, Sinagra G, Piacenti M, Zacchigna S, Bussani R, Recchia FA, Giacca M.

Nature. 2019 May;569(7756):418-422. doi: 10.1038/s41586-019-1191-6. Epub 2019 May 8.

13.

High-throughput screening discovers antifibrotic properties of haloperidol by hindering myofibroblast activation.

Rehman M, Vodret S, Braga L, Guarnaccia C, Celsi F, Rossetti G, Martinelli V, Battini T, Long C, Vukusic K, Kocijan T, Collesi C, Ring N, Skoko N, Giacca M, Del Sal G, Confalonieri M, Raspa M, Marcello A, Myers MP, Crovella S, Carloni P, Zacchigna S.

JCI Insight. 2019 Apr 18;4(8). pii: 123987. doi: 10.1172/jci.insight.123987. eCollection 2019 Apr 18.

14.

Reactivating endogenous mechanisms of cardiac regeneration via paracrine boosting using the human amniotic fluid stem cell secretome.

Balbi C, Lodder K, Costa A, Moimas S, Moccia F, van Herwaarden T, Rosti V, Campagnoli F, Palmeri A, De Biasio P, Santini F, Giacca M, Goumans MJ, Barile L, Smits AM, Bollini S.

Int J Cardiol. 2019 Jul 15;287:87-95. doi: 10.1016/j.ijcard.2019.04.011. Epub 2019 Apr 4.

PMID:
30987834
15.

Intracoronary Gene Delivery of the Cytoprotective Factor Vascular Endothelial Growth Factor-B167 in Canine Patients with Dilated Cardiomyopathy: A Short-Term Feasibility Study.

Paradies P, Carlucci L, Woitek F, Staffieri F, Lacitignola L, Ceci L, Romano D, Sasanelli M, Zentilin L, Giacca M, Salvadori S, Crovace A, Recchia FA.

Vet Sci. 2019 Mar 6;6(1). pii: E23. doi: 10.3390/vetsci6010023.

16.

Endothelial cell-cardiomyocyte crosstalk in heart development and disease.

Colliva A, Braga L, Giacca M, Zacchigna S.

J Physiol. 2019 Feb 28. doi: 10.1113/JP276758. [Epub ahead of print]

PMID:
30816576
17.

Cellular TRIM33 restrains HIV-1 infection by targeting viral integrase for proteasomal degradation.

Ali H, Mano M, Braga L, Naseem A, Marini B, Vu DM, Collesi C, Meroni G, Lusic M, Giacca M.

Nat Commun. 2019 Feb 25;10(1):926. doi: 10.1038/s41467-019-08810-0.

18.

MicroRNA hsa-miR-29a-3p is a plasma biomarker for the differential diagnosis and monitoring of tuberculosis.

Ndzi EN, Nkenfou CN, Mekue LM, Zentilin L, Tamgue O, Pefura EWY, Kuiaté JR, Giacca M, Ndjolo A.

Tuberculosis (Edinb). 2019 Jan;114:69-76. doi: 10.1016/j.tube.2018.12.001. Epub 2018 Dec 6.

PMID:
30711160
19.

Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure.

Raso A, Dirkx E, Philippen LE, Fernandez-Celis A, De Majo F, Sampaio-Pinto V, Sansonetti M, Juni R, El Azzouzi H, Calore M, Bitsch N, Olieslagers S, Oerlemans MIFJ, Huibers MM, de Weger RA, Reckman YJ, Pinto YM, Zentilin L, Zacchigna S, Giacca M, da Costa Martins PA, López-Andrés N, De Windt LJ.

Mol Ther. 2019 Mar 6;27(3):584-599. doi: 10.1016/j.ymthe.2018.11.011. Epub 2018 Nov 17.

20.

TBL1Y: a new gene involved in syndromic hearing loss.

Di Stazio M, Collesi C, Vozzi D, Liu W, Myers M, Morgan A, D Adamo PA, Girotto G, Rubinato E, Giacca M, Gasparini P.

Eur J Hum Genet. 2019 Mar;27(3):466-474. doi: 10.1038/s41431-018-0282-4. Epub 2018 Oct 19.

PMID:
30341416
21.

VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9.

Montagna C, Petris G, Casini A, Maule G, Franceschini GM, Zanella I, Conti L, Arnoldi F, Burrone OR, Zentilin L, Zacchigna S, Giacca M, Cereseto A.

Mol Ther Nucleic Acids. 2018 Sep 7;12:453-462. doi: 10.1016/j.omtn.2018.05.010. Epub 2018 Jul 11.

22.

Non-coding RNA function in stem cells and Regenerative Medicine.

De Windt LJ, Giacca M.

Noncoding RNA Res. 2018 Apr 20;3(2):39-41. doi: 10.1016/j.ncrna.2018.04.004. eCollection 2018 Jun. No abstract available.

23.

Notch pathway activation enhances cardiosphere in vitro expansion.

Secco I, Barile L, Torrini C, Zentilin L, Vassalli G, Giacca M, Collesi C.

J Cell Mol Med. 2018 Nov;22(11):5583-5595. doi: 10.1111/jcmm.13832. Epub 2018 Aug 23.

24.

The global role of biotechnology for non communicable disorders.

Zacchigna S, Giacca M.

J Biotechnol. 2018 Oct 10;283:115-119. doi: 10.1016/j.jbiotec.2018.07.043. Epub 2018 Aug 2. Review.

PMID:
30077584
25.

AAV9-mediated Rbm24 overexpression induces fibrosis in the mouse heart.

van den Hoogenhof MMG, van der Made I, de Groot NE, Damanafshan A, van Amersfoorth SCM, Zentilin L, Giacca M, Pinto YM, Creemers EE.

Sci Rep. 2018 Aug 3;8(1):11696. doi: 10.1038/s41598-018-29552-x.

26.

Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction.

Zacchigna S, Martinelli V, Moimas S, Colliva A, Anzini M, Nordio A, Costa A, Rehman M, Vodret S, Pierro C, Colussi G, Zentilin L, Gutierrez MI, Dirkx E, Long C, Sinagra G, Klatzmann D, Giacca M.

Nat Commun. 2018 Jun 26;9(1):2432. doi: 10.1038/s41467-018-04908-z.

27.

A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent.

Gioelli N, Maione F, Camillo C, Ghitti M, Valdembri D, Morello N, Darche M, Zentilin L, Cagnoni G, Qiu Y, Giacca M, Giustetto M, Paques M, Cascone I, Musco G, Tamagnone L, Giraudo E, Serini G.

Sci Transl Med. 2018 May 23;10(442). pii: eaah4807. doi: 10.1126/scitranslmed.aah4807. Erratum in: Sci Transl Med. 2018 Jul 25;10(451):.

28.

Analysis of Preoperative Portal Vein Embolization Outcomes in Patients with Hepatocellular Carcinoma: A Single-Center Experience.

Marti J, Giacca M, Alshebeeb K, Bahl S, Hua C, Horn JC, BouAyache J, Patel R, Facciuto M, Schwartz M, Florman S, Kim E, Gunasekaran G.

J Vasc Interv Radiol. 2018 Jul;29(7):920-926. doi: 10.1016/j.jvir.2018.01.780. Epub 2018 May 5.

PMID:
29735260
29.

MiR-16 regulates the pro-tumorigenic potential of lung fibroblasts through the inhibition of HGF production in an FGFR-1- and MEK1-dependent manner.

Andriani F, Majorini MT, Mano M, Landoni E, Miceli R, Facchinetti F, Mensah M, Fontanella E, Dugo M, Giacca M, Pastorino U, Sozzi G, Delia D, Roz L, Lecis D.

J Hematol Oncol. 2018 Mar 20;11(1):45. doi: 10.1186/s13045-018-0594-4.

30.

HPV-16 virions can remain infectious for 2 weeks on senescent cells but require cell cycle re-activation to allow virus entry.

Broniarczyk J, Ring N, Massimi P, Giacca M, Banks L.

Sci Rep. 2018 Jan 16;8(1):811. doi: 10.1038/s41598-017-18809-6.

31.

The innate immune system in chronic cardiomyopathy: a European Society of Cardiology (ESC) scientific statement from the Working Group on Myocardial Function of the ESC.

Frantz S, Falcao-Pires I, Balligand JL, Bauersachs J, Brutsaert D, Ciccarelli M, Dawson D, de Windt LJ, Giacca M, Hamdani N, Hilfiker-Kleiner D, Hirsch E, Leite-Moreira A, Mayr M, Thum T, Tocchetti CG, van der Velden J, Varricchi G, Heymans S.

Eur J Heart Fail. 2018 Mar;20(3):445-459. doi: 10.1002/ejhf.1138. Epub 2018 Jan 15. Review.

32.

Epigenetic silencing of miR-296 and miR-512 ensures hTERT dependent apoptosis protection and telomere maintenance in basal-type breast cancer cells.

Dinami R, Buemi V, Sestito R, Zappone A, Ciani Y, Mano M, Petti E, Sacconi A, Blandino G, Giacca M, Piazza S, Benetti R, Schoeftner S.

Oncotarget. 2017 Sep 23;8(56):95674-95691. doi: 10.18632/oncotarget.21180. eCollection 2017 Nov 10.

33.

Reversible Notch1 acetylation tunes proliferative signalling in cardiomyocytes.

Collesi C, Felician G, Secco I, Gutierrez MI, Martelletti E, Ali H, Zentilin L, Myers MP, Giacca M.

Cardiovasc Res. 2018 Jan 1;114(1):103-122. doi: 10.1093/cvr/cvx228.

PMID:
29186476
34.

An integrative translational approach to study heart failure with preserved ejection fraction: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology.

Lourenço AP, Leite-Moreira AF, Balligand JL, Bauersachs J, Dawson D, de Boer RA, de Windt LJ, Falcão-Pires I, Fontes-Carvalho R, Franz S, Giacca M, Hilfiker-Kleiner D, Hirsch E, Maack C, Mayr M, Pieske B, Thum T, Tocchetti CG, Brutsaert DL, Heymans S.

Eur J Heart Fail. 2018 Feb;20(2):216-227. doi: 10.1002/ejhf.1059. Epub 2017 Nov 16. Review.

35.

Acylated ghrelin treatment normalizes skeletal muscle mitochondrial oxidative capacity and AKT phosphorylation in rat chronic heart failure.

Barazzoni R, Gortan Cappellari G, Palus S, Vinci P, Ruozi G, Zanetti M, Semolic A, Ebner N, von Haehling S, Sinagra G, Giacca M, Springer J.

J Cachexia Sarcopenia Muscle. 2017 Dec;8(6):991-998. doi: 10.1002/jcsm.12254. Epub 2017 Nov 3.

36.

Laparoscopic ileocolic iterative resection with fluorescence-guided lymphatic mapping - a video vignette.

Silvestri M, Guerra M, Giacca M, Casagranda B, Palmisano S, de Manzini N.

Colorectal Dis. 2017 Oct;19(10):945-946. doi: 10.1111/codi.13881. No abstract available.

PMID:
28906577
37.

Identification of HSP90 inhibitors as a novel class of senolytics.

Fuhrmann-Stroissnigg H, Ling YY, Zhao J, McGowan SJ, Zhu Y, Brooks RW, Grassi D, Gregg SQ, Stripay JL, Dorronsoro A, Corbo L, Tang P, Bukata C, Ring N, Giacca M, Li X, Tchkonia T, Kirkland JL, Niedernhofer LJ, Robbins PD.

Nat Commun. 2017 Sep 4;8(1):422. doi: 10.1038/s41467-017-00314-z.

38.

Postnatal Cardiac Gene Editing Using CRISPR/Cas9 With AAV9-Mediated Delivery of Short Guide RNAs Results in Mosaic Gene Disruption.

Johansen AK, Molenaar B, Versteeg D, Leitoguinho AR, Demkes C, Spanjaard B, de Ruiter H, Akbari Moqadam F, Kooijman L, Zentilin L, Giacca M, van Rooij E.

Circ Res. 2017 Oct 27;121(10):1168-1181. doi: 10.1161/CIRCRESAHA.116.310370. Epub 2017 Aug 29.

PMID:
28851809
39.

Repeated AAV-mediated gene transfer by serotype switching enables long-lasting therapeutic levels of hUgt1a1 enzyme in a mouse model of Crigler-Najjar Syndrome Type I.

Bočkor L, Bortolussi G, Iaconcig A, Chiaruttini G, Tiribelli C, Giacca M, Benvenuti F, Zentilin L, Muro AF.

Gene Ther. 2017 Oct;24(10):649-660. doi: 10.1038/gt.2017.75. Epub 2017 Aug 14.

PMID:
28805798
40.

Id genes are essential for early heart formation.

Cunningham TJ, Yu MS, McKeithan WL, Spiering S, Carrette F, Huang CT, Bushway PJ, Tierney M, Albini S, Giacca M, Mano M, Puri PL, Sacco A, Ruiz-Lozano P, Riou JF, Umbhauer M, Duester G, Mercola M, Colas AR.

Genes Dev. 2017 Jul 1;31(13):1325-1338. doi: 10.1101/gad.300400.117. Epub 2017 Aug 9.

41.

Unacylated ghrelin normalizes skeletal muscle oxidative stress and prevents muscle catabolism by enhancing tissue mitophagy in experimental chronic kidney disease.

Gortan Cappellari G, Semolic A, Ruozi G, Vinci P, Guarnieri G, Bortolotti F, Barbetta D, Zanetti M, Giacca M, Barazzoni R.

FASEB J. 2017 Dec;31(12):5159-5171. doi: 10.1096/fj.201700126R. Epub 2017 Aug 4.

PMID:
28778977
42.

In Vivo Functional Selection Identifies Cardiotrophin-1 as a Cardiac Engraftment Factor for Mesenchymal Stromal Cells.

Bortolotti F, Ruozi G, Falcione A, Doimo S, Dal Ferro M, Lesizza P, Zentilin L, Banks L, Zacchigna S, Giacca M.

Circulation. 2017 Oct 17;136(16):1509-1524. doi: 10.1161/CIRCULATIONAHA.117.029003. Epub 2017 Jul 28.

PMID:
28754835
43.

MiR-320a as a Potential Novel Circulating Biomarker of Arrhythmogenic CardioMyopathy.

Sommariva E, D'Alessandra Y, Farina FM, Casella M, Cattaneo F, Catto V, Chiesa M, Stadiotti I, Brambilla S, Dello Russo A, Carbucicchio C, Vettor G, Riggio D, Sandri MT, Barbuti A, Vernillo G, Muratori M, Dal Ferro M, Sinagra G, Moimas S, Giacca M, Colombo GI, Pompilio G, Tondo C.

Sci Rep. 2017 Jul 6;7(1):4802. doi: 10.1038/s41598-017-05001-z.

44.

Cardiomyocyte Regeneration: A Consensus Statement.

Eschenhagen T, Bolli R, Braun T, Field LJ, Fleischmann BK, Frisén J, Giacca M, Hare JM, Houser S, Lee RT, Marbán E, Martin JF, Molkentin JD, Murry CE, Riley PR, Ruiz-Lozano P, Sadek HA, Sussman MA, Hill JA.

Circulation. 2017 Aug 15;136(7):680-686. doi: 10.1161/CIRCULATIONAHA.117.029343. Epub 2017 Jul 6. Review. No abstract available.

45.

Biotechnology and the bioeconomy-Towards inclusive and sustainable industrial development.

Lokko Y, Heijde M, Schebesta K, Scholtès P, Van Montagu M, Giacca M.

N Biotechnol. 2018 Jan 25;40(Pt A):5-10. doi: 10.1016/j.nbt.2017.06.005. Epub 2017 Jun 27. Review.

PMID:
28663120
46.

Inhibition of Non Canonical HIV-1 Tat Secretion Through the Cellular Na+,K+-ATPase Blocks HIV-1 Infection.

Agostini S, Ali H, Vardabasso C, Fittipaldi A, Tasciotti E, Cereseto A, Bugatti A, Rusnati M, Lusic M, Giacca M.

EBioMedicine. 2017 Jul;21:170-181. doi: 10.1016/j.ebiom.2017.06.011. Epub 2017 Jun 13.

47.

NEUROD1 Instructs Neuronal Conversion in Non-Reactive Astrocytes.

Brulet R, Matsuda T, Zhang L, Miranda C, Giacca M, Kaspar BK, Nakashima K, Hsieh J.

Stem Cell Reports. 2017 Jun 6;8(6):1506-1515. doi: 10.1016/j.stemcr.2017.04.013. Epub 2017 May 11.

48.

Effectiveness of Intraoperative Parathyroid Monitoring (ioPTH) in predicting a multiglandular or malignant parathyroid disease.

Dobrinja C, Santandrea G, Giacca M, Stenner E, Ruscio M, de Manzini N.

Int J Surg. 2017 May;41 Suppl 1:S26-S33. doi: 10.1016/j.ijsu.2017.02.063.

49.

Unacylated Ghrelin Enhances Satellite Cell Function and Relieves the Dystrophic Phenotype in Duchenne Muscular Dystrophy mdx Model.

Reano S, Angelino E, Ferrara M, Malacarne V, Sustova H, Sabry O, Agosti E, Clerici S, Ruozi G, Zentilin L, Prodam F, Geuna S, Giacca M, Graziani A, Filigheddu N.

Stem Cells. 2017 Jul;35(7):1733-1746. doi: 10.1002/stem.2632. Epub 2017 May 7.

50.

Association between mutation status and left ventricular reverse remodelling in dilated cardiomyopathy.

Dal Ferro M, Stolfo D, Altinier A, Gigli M, Perrieri M, Ramani F, Barbati G, Pivetta A, Brun F, Monserrat L, Giacca M, Mestroni L, Merlo M, Sinagra G.

Heart. 2017 Nov;103(21):1704-1710. doi: 10.1136/heartjnl-2016-311017. Epub 2017 Apr 17.

PMID:
28416588

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