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Items: 1 to 50 of 223

2.

Differential functionalities of amphiphilic peptide segments of the cell-septation penicillin-binding protein 3 of Escherichia coli.

Marrec-Fairley M, Piette A, Gallet X, Brasseur R, Hara H, Fraipont C, Ghuysen JM, Nguyen-Distèche M.

Mol Microbiol. 2000 Sep;37(5):1019-31.

3.

The catalytic, glycosyl transferase and acyl transferase modules of the cell wall peptidoglycan-polymerizing penicillin-binding protein 1b of Escherichia coli.

Terrak M, Ghosh TK, van Heijenoort J, Van Beeumen J, Lampilas M, Aszodi J, Ayala JA, Ghuysen JM, Nguyen-Distèche M.

Mol Microbiol. 1999 Oct;34(2):350-64.

4.

The division and cell wall gene cluster of Enterococcus hirae S185.

Duez C, Thamm I, Sapunaric F, Coyette J, Ghuysen JM.

DNA Seq. 1998;9(3):149-61.

5.

Lack of cell wall peptidoglycan versus penicillin sensitivity: new insights into the chlamydial anomaly.

Ghuysen JM, Goffin C.

Antimicrob Agents Chemother. 1999 Oct;43(10):2339-44. Review. No abstract available.

6.

[The bacterial cell wall and penicillin resistance: facts, questions and hopes].

Ghuysen JM.

Bull Mem Acad R Med Belg. 1998;153(4):235-41. French.

PMID:
9887589
7.

[Bacterial resistance to antibiotics, an exemplary model of directed molecular evolution].

Ghuysen JM.

Verh K Acad Geneeskd Belg. 1998;60(4):287-94. French.

8.

Multimodular penicillin-binding proteins: an enigmatic family of orthologs and paralogs.

Goffin C, Ghuysen JM.

Microbiol Mol Biol Rev. 1998 Dec;62(4):1079-93. Review.

9.

[Bacterial resistance to antibiotics, an exemplary model of directed molecular evolution].

Ghuysen JM.

Rev Med Liege. 1998 Sep;53(9):529-31. Review. French.

10.

The gene encoding the low-affinity penicillin-binding protein 3r in Enterococcus hirae S185R is borne on a plasmid carrying other antibiotic resistance determinants.

Raze D, Dardenne O, Hallut S, Martinez-Bueno M, Coyette J, Ghuysen JM.

Antimicrob Agents Chemother. 1998 Mar;42(3):534-9.

11.

Site-directed mutagenesis of the Actinomadura R39 DD-peptidase.

Zhao GH, Duez C, Lepage S, Forceille C, Rhazi N, Klein D, Ghuysen JM, Frère JM.

Biochem J. 1997 Oct 15;327 ( Pt 2):377-81.

12.

The bimodular G57-V577 polypeptide chain of the class B penicillin-binding protein 3 of Escherichia coli catalyzes peptide bond formation from thiolesters and does not catalyze glycan chain polymerization from the lipid II intermediate.

Adam M, Fraipont C, Rhazi N, Nguyen-Distèche M, Lakaye B, Frère JM, Devreese B, Van Beeumen J, van Heijenoort Y, van Heijenoort J, Ghuysen JM.

J Bacteriol. 1997 Oct;179(19):6005-9.

13.

Dual multimodular class A penicillin-binding proteins in Mycobacterium leprae.

Lepage S, Dubois P, Ghosh TK, Joris B, Mahapatra S, Kundu M, Basu J, Chakrabarti P, Cole ST, Nguyen-Distèche M, Ghuysen JM.

J Bacteriol. 1997 Jul;179(14):4627-30.

14.
15.
16.

Cloning, sequencing and overexpression in Escherichia coli of the alginatelyase-encoding aly gene of Pseudomonas alginovora: identification of three classes of alginate lyases.

Chavagnat F, Duez C, Guinand M, Potin P, Barbeyron T, Henrissat B, Wallach J, Ghuysen JM.

Biochem J. 1996 Oct 15;319 ( Pt 2):575-83.

18.

Penicillin and beyond: evolution, protein fold, multimodular polypeptides, and multiprotein complexes.

Ghuysen JM, Charlier P, Coyette J, Duez C, Fonzé E, Fraipont C, Goffin C, Joris B, Nguyen-Distèche M.

Microb Drug Resist. 1996 Summer;2(2):163-75. Review.

20.

Identification and overexpression in Escherichia coli of a Mycobacterium leprae gene, pon1, encoding a high-molecular-mass class A penicillin-binding protein, PBP1.

Basu J, Mahapatra S, Kundu M, Mukhopadhyay S, Nguyen-Distèche M, Dubois P, Joris B, Van Beeumen J, Cole ST, Chakrabarti P, Ghuysen JM.

J Bacteriol. 1996 Mar;178(6):1707-11.

21.
22.

Overproduction and properties of the mannuronate alginate lyase AlxMB.

Malissard M, Chavagnat F, Duez C, Vacheron MJ, Guinand M, Michel G, Ghuysen JM.

FEMS Microbiol Lett. 1995 Feb 15;126(2):105-11.

23.
24.

Primary structure of the Streptomyces R61 extracellular DD-peptidase. 1. Cloning into Streptomyces lividans and nucleotide sequence of the gene.

Duez C, Piron-Fraipont C, Joris B, Dusart J, Urdea MS, Martial JA, Frère JM, Ghuysen JM.

Eur J Biochem. 1994 Sep 15;224(3):1079. No abstract available.

25.

The precursor of the Streptomyces R61 DD-peptidase containing a C-terminal extension is inactive.

Fanuel L, Granier B, Wilkin JM, Bellefroid-Bourguignon C, Joris B, Knowles J, Komives E, Van Beeumen J, Ghuysen JM, Frère JM.

FEBS Lett. 1994 Aug 29;351(1):49-52.

26.

Site-directed mutagenesis of penicillin-binding protein 3 of Escherichia coli: role of Val-545.

Ayala J, Goffin C, Nguyen-Distèche M, Ghuysen JM.

FEMS Microbiol Lett. 1994 Aug 15;121(2):251-6.

27.

Binding site-shaped repeated sequences of bacterial wall peptidoglycan hydrolases.

Ghuysen JM, Lamotte-Brasseur J, Joris B, Shockman GD.

FEBS Lett. 1994 Mar 28;342(1):23-8.

28.

Engineering and overexpression of periplasmic forms of the penicillin-binding protein 3 of Escherichia coli.

Fraipont C, Adam M, Nguyen-Distèche M, Keck W, Van Beeumen J, Ayala JA, Granier B, Hara H, Ghuysen JM.

Biochem J. 1994 Feb 15;298 ( Pt 1):189-95.

29.
30.
31.

Sequence of a gene encoding a (poly ManA) alginate lyase active on Pseudomonas aeruginosa alginate.

Malissard M, Duez C, Guinand M, Vacheron MJ, Michel G, Marty N, Joris B, Thamm I, Ghuysen JM.

FEMS Microbiol Lett. 1993 Jun 1;110(1):101-6.

32.
33.

Secretion by overexpression and purification of the water-soluble Streptomyces K15 DD-transpeptidase/penicillin-binding protein.

Palomeque-Messia P, Quittre V, Leyh-Bouille M, Nguyen-Distèche M, Gershater CJ, Dacey IK, Dusart J, Van Beeumen J, Ghuysen JM.

Biochem J. 1992 Nov 15;288 ( Pt 1):87-91.

34.

Structure, function, and fate of the BlaR signal transducer involved in induction of beta-lactamase in Bacillus licheniformis.

Zhu Y, Englebert S, Joris B, Ghuysen JM, Kobayashi T, Lampen JO.

J Bacteriol. 1992 Oct;174(19):6171-8.

35.

Primary and predicted secondary structure of the Actinomadura R39 extracellular DD-peptidase, a penicillin-binding protein (PBP) related to the Escherichia coli PBP4.

Granier B, Duez C, Lepage S, Englebert S, Dusart J, Dideberg O, Van Beeumen J, Frère JM, Ghuysen JM.

Biochem J. 1992 Sep 15;286 ( Pt 3):981-2. No abstract available.

36.

Site-directed mutagenesis of the Streptomyces R61 DD-peptidase. Catalytic function of the conserved residues around the active site and a comparison with class-A and class-C beta-lactamases.

Hadonou AM, Wilkin JM, Varetto L, Joris B, Lamotte-Brasseur J, Klein D, Duez C, Ghuysen JM, Frère JM.

Eur J Biochem. 1992 Jul 1;207(1):97-102.

37.

Point mutations of two arginine residues in the Streptomyces R61 DD-peptidase.

Bourguignon-Bellefroid C, Joris B, Van Beeumen J, Ghuysen JM, Frère JM.

Biochem J. 1992 Apr 1;283 ( Pt 1):123-8.

38.

Primary and predicted secondary structures of the Actinomadura R39 extracellular DD-peptidase, a penicillin-binding protein (PBP) related to the Escherichia coli PBP4.

Granier B, Duez C, Lepage S, Englebert S, Dusart J, Dideberg O, Van Beeumen J, Frère JM, Ghuysen JM.

Biochem J. 1992 Mar 15;282 ( Pt 3):781-8. Erratum in: Biochem J. 1992 Sep 15;286 ( Pt 3):981-2.

39.

Modular design of the Enterococcus hirae muramidase-2 and Streptococcus faecalis autolysin.

Joris B, Englebert S, Chu CP, Kariyama R, Daneo-Moore L, Shockman GD, Ghuysen JM.

FEMS Microbiol Lett. 1992 Mar 15;70(3):257-64.

40.

Cloning and nucleotide sequence of the gene encoding the gamma-D-glutamyl-L-diamino acid endopeptidase II of Bacillus sphaericus.

Hourdou ML, Duez C, Joris B, Vacheron MJ, Guinand M, Michel G, Ghuysen JM.

FEMS Microbiol Lett. 1992 Mar 1;70(2):165-70.

41.

Importance of the His-298 residue in the catalytic mechanism of the Streptomyces R61 extracellular DD-peptidase.

Hadonou AM, Jamin M, Adam M, Joris B, Dusart J, Ghuysen JM, Frère JM.

Biochem J. 1992 Mar 1;282 ( Pt 2):495-500.

42.

Importance of the two tryptophan residues in the Streptomyces R61 exocellular DD-peptidase.

Bourguignon-Bellefroid C, Wilkin JM, Joris B, Aplin RT, Houssier C, Prendergast FG, Van Beeumen J, Ghuysen JM, Frère JM.

Biochem J. 1992 Mar 1;282 ( Pt 2):361-7.

43.

Streptomyces albus G serine beta-lactamase. Probing of the catalytic mechanism via molecular modelling of mutant enzymes.

Lamotte-Brasseur J, Jacob-Dubuisson F, Dive G, Frère JM, Ghuysen JM.

Biochem J. 1992 Feb 15;282 ( Pt 1):189-95.

44.

The Enterococcus hirae R40 penicillin-binding protein 5 and the methicillin-resistant Staphylococcus aureus penicillin-binding protein 2' are similar.

el Kharroubi A, Jacques P, Piras G, Van Beeumen J, Coyette J, Ghuysen JM.

Biochem J. 1991 Dec 1;280 ( Pt 2):463-9.

45.

Comparison of the sequences of class A beta-lactamases and of the secondary structure elements of penicillin-recognizing proteins.

Joris B, Ledent P, Dideberg O, Fonzé E, Lamotte-Brasseur J, Kelly JA, Ghuysen JM, Frère JM.

Antimicrob Agents Chemother. 1991 Nov;35(11):2294-301.

46.

Amino acid sequence of the penicillin-binding protein/DD-peptidase of Streptomyces K15. Predicted secondary structures of the low Mr penicillin-binding proteins of class A.

Palomeque-Messia P, Englebert S, Leyh-Bouille M, Nguyen-Distèche M, Duez C, Houba S, Dideberg O, Van Beeumen J, Ghuysen JM.

Biochem J. 1991 Oct 1;279 ( Pt 1):223-30.

47.

Mechanism of acyl transfer by the class A serine beta-lactamase of Streptomyces albus G.

Lamotte-Brasseur J, Dive G, Dideberg O, Charlier P, Frère JM, Ghuysen JM.

Biochem J. 1991 Oct 1;279 ( Pt 1):213-21.

48.

Mode of membrane insertion and sequence of a 32-amino acid peptide stretch of the penicillin-binding protein 4 of Enterococcus hirae.

Jacques P, el Kharroubi A, Van Beeumen J, Piras G, Coyette J, Ghuysen JM.

FEMS Microbiol Lett. 1991 Aug 1;66(2):119-23.

49.

A standard numbering scheme for the class A beta-lactamases.

Ambler RP, Coulson AF, Frère JM, Ghuysen JM, Joris B, Forsman M, Levesque RC, Tiraby G, Waley SG.

Biochem J. 1991 May 15;276 ( Pt 1):269-70. No abstract available.

50.

[Basic research and medicine].

Ghuysen JM.

Rev Med Liege. 1991 Mar;46(3):115-22. French. No abstract available.

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