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Items: 23

1.

Higher order genomic organization and epigenetic control maintain cellular identity and prevent breast cancer.

Fritz AJ, Gillis NE, Gerrard DL, Rodriguez PD, Hong D, Rose JT, Ghule PN, Bolf EL, Gordon JA, Tye CE, Boyd JR, Tracy KM, Nickerson JA, van Wijnen AJ, Imbalzano AN, Heath JL, Frietze SE, Zaidi SK, Carr FE, Lian JB, Stein JL, Stein GS.

Genes Chromosomes Cancer. 2019 Jul;58(7):484-499. doi: 10.1002/gcc.22731. Epub 2019 Mar 15. Review.

PMID:
30873710
2.

Higher order genomic organization and regulatory compartmentalization for cell cycle control at the G1/S-phase transition.

Ghule PN, Seward DJ, Fritz AJ, Boyd JR, van Wijnen AJ, Lian JB, Stein JL, Stein GS.

J Cell Physiol. 2018 Oct;233(10):6406-6413. doi: 10.1002/jcp.26741. Epub 2018 May 10. Review.

3.

Mitotically-Associated lncRNA (MANCR) Affects Genomic Stability and Cell Division in Aggressive Breast Cancer.

Tracy KM, Tye CE, Ghule PN, Malaby HLH, Stumpff J, Stein JL, Stein GS, Lian JB.

Mol Cancer Res. 2018 Apr;16(4):587-598. doi: 10.1158/1541-7786.MCR-17-0548. Epub 2018 Jan 29.

4.

Intranuclear and higher-order chromatin organization of the major histone gene cluster in breast cancer.

Fritz AJ, Ghule PN, Boyd JR, Tye CE, Page NA, Hong D, Shirley DJ, Weinheimer AS, Barutcu AR, Gerrard DL, Frietze S, van Wijnen AJ, Zaidi SK, Imbalzano AN, Lian JB, Stein JL, Stein GS.

J Cell Physiol. 2018 Feb;233(2):1278-1290. doi: 10.1002/jcp.25996. Epub 2017 Jun 22.

5.

Transient RUNX1 Expression during Early Mesendodermal Differentiation of hESCs Promotes Epithelial to Mesenchymal Transition through TGFB2 Signaling.

VanOudenhove JJ, Medina R, Ghule PN, Lian JB, Stein JL, Zaidi SK, Stein GS.

Stem Cell Reports. 2016 Nov 8;7(5):884-896. doi: 10.1016/j.stemcr.2016.09.006. Epub 2016 Oct 6.

6.

Maternal expression and early induction of histone gene transcription factor Hinfp sustains development in pre-implantation embryos.

Ghule PN, Xie RL, Colby JL, Rivera-Pérez JA, Jones SN, Lian JB, Stein JL, van Wijnen AJ, Stein GS.

Dev Biol. 2016 Nov 15;419(2):311-320. doi: 10.1016/j.ydbio.2016.09.003. Epub 2016 Sep 5.

7.

Precocious Phenotypic Transcription-Factor Expression During Early Development.

VanOudenhove JJ, Medina R, Ghule PN, Lian JB, Stein JL, Zaidi SK, Stein GS.

J Cell Biochem. 2017 May;118(5):953-958. doi: 10.1002/jcb.25723. Epub 2017 Jan 11. Review.

8.

Unique Regulatory Mechanisms for the Human Embryonic Stem Cell Cycle.

VanOudenhove JJ, Grandy RA, Ghule PN, Lian JB, Stein JL, Zaidi SK, Stein GS.

J Cell Physiol. 2017 Jun;232(6):1254-1257. doi: 10.1002/jcp.25567. Epub 2017 Jan 31. Review.

9.

Lineage-Specific Early Differentiation of Human Embryonic Stem Cells Requires a G2 Cell Cycle Pause.

Van Oudenhove JJ, Grandy RA, Ghule PN, Del Rio R, Lian JB, Stein JL, Zaidi SK, Stein GS.

Stem Cells. 2016 Jul;34(7):1765-75. doi: 10.1002/stem.2352. Epub 2016 Mar 28. Erratum in: Stem Cells. 2016 Oct;34(10 ):2612.

10.

p53 checkpoint ablation exacerbates the phenotype of Hinfp dependent histone H4 deficiency.

Ghule PN, Xie RL, Colby JL, Jones SN, Lian JB, Wijnen AJ, Stein JL, Stein GS.

Cell Cycle. 2015 Aug 3;14(15):2501-8. doi: 10.1080/15384101.2015.1049783. Epub 2015 Jun 1.

11.

Cell cycle gene expression networks discovered using systems biology: Significance in carcinogenesis.

Scott RE, Ghule PN, Stein JL, Stein GS.

J Cell Physiol. 2015 Oct;230(10):2533-42. doi: 10.1002/jcp.24990.

12.

Spindle microtubule dysfunction and cancer predisposition.

Stumpff J, Ghule PN, Shimamura A, Stein JL, Greenblatt M.

J Cell Physiol. 2014 Dec;229(12):1881-3. doi: 10.1002/jcp.24691.

13.

Fidelity of histone gene regulation is obligatory for genome replication and stability.

Ghule PN, Xie RL, Medina R, Colby JL, Jones SN, Lian JB, Stein JL, van Wijnen AJ, Stein GS.

Mol Cell Biol. 2014 Jul;34(14):2650-9.

14.

Epigenetic control of cell cycle-dependent histone gene expression is a principal component of the abbreviated pluripotent cell cycle.

Medina R, Ghule PN, Cruzat F, Barutcu AR, Montecino M, Stein JL, van Wijnen AJ, Stein GS.

Mol Cell Biol. 2012 Oct;32(19):3860-71. doi: 10.1128/MCB.00736-12. Epub 2012 Jul 23.

15.

Reprogramming the pluripotent cell cycle: restoration of an abbreviated G1 phase in human induced pluripotent stem (iPS) cells.

Ghule PN, Medina R, Lengner CJ, Mandeville M, Qiao M, Dominski Z, Lian JB, Stein JL, van Wijnen AJ, Stein GS.

J Cell Physiol. 2011 May;226(5):1149-56. doi: 10.1002/jcp.22440.

16.

Cyclin D2 and the CDK substrate p220(NPAT) are required for self-renewal of human embryonic stem cells.

Becker KA, Ghule PN, Lian JB, Stein JL, van Wijnen AJ, Stein GS.

J Cell Physiol. 2010 Feb;222(2):456-64. doi: 10.1002/jcp.21967.

17.

Survival responses of human embryonic stem cells to DNA damage.

Filion TM, Qiao M, Ghule PN, Mandeville M, van Wijnen AJ, Stein JL, Lian JB, Altieri DC, Stein GS.

J Cell Physiol. 2009 Sep;220(3):586-92. doi: 10.1002/jcp.21735.

18.
19.

CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P.

Mitra P, Ghule PN, van der Deen M, Medina R, Xie RL, Holmes WF, Ye X, Nakayama KI, Harper JW, Stein JL, Stein GS, van Wijnen AJ.

J Cell Physiol. 2009 May;219(2):438-48. doi: 10.1002/jcp.21687.

20.

Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cells.

Ghule PN, Dominski Z, Yang XC, Marzluff WF, Becker KA, Harper JW, Lian JB, Stein JL, van Wijnen AJ, Stein GS.

Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):16964-9. doi: 10.1073/pnas.0809273105. Epub 2008 Oct 28.

21.

Cell cycle dependent phosphorylation and subnuclear organization of the histone gene regulator p220(NPAT) in human embryonic stem cells.

Ghule PN, Becker KA, Harper JW, Lian JB, Stein JL, van Wijnen AJ, Stein GS.

J Cell Physiol. 2007 Oct;213(1):9-17. Review.

PMID:
17520687
22.

Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase.

Becker KA, Ghule PN, Therrien JA, Lian JB, Stein JL, van Wijnen AJ, Stein GS.

J Cell Physiol. 2006 Dec;209(3):883-93.

PMID:
16972248
23.

Constitutional and somatic RB1 mutation spectrum in nonfamilial unilateral and bilateral retinoblastoma in India.

Bamne MN, Ghule PN, Jose J, Banavali SD, Kurkure PA, Amare Kadam PS.

Genet Test. 2005 Fall;9(3):200-11.

PMID:
16225399

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