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Items: 1 to 50 of 201

1.

Long-Term Oncologic Outcomes After Curative Resection of Familial Medullary Thyroid Carcinoma.

Spanheimer PM, Ganly I, Chou J, Capanu M, Ghossein RA, Tuttle RM, Wong RJ, Shaha AR, Untch BR.

Ann Surg Oncol. 2019 Dec;26(13):4423-4429. doi: 10.1245/s10434-019-07869-9. Epub 2019 Sep 23.

PMID:
31549322
2.

Should multifocality be an indication for completion thyroidectomy in papillary thyroid carcinoma?

Harries V, Wang LY, McGill M, Xu B, Tuttle RM, Wong RJ, Shaha AR, Shah JP, Ghossein R, Patel SG, Ganly I.

Surgery. 2019 Sep 9. pii: S0039-6060(19)30512-4. doi: 10.1016/j.surg.2019.03.031. [Epub ahead of print]

PMID:
31515125
3.

Histologic spectrum of polymorphous adenocarcinoma of the salivary gland harbor genetic alterations affecting PRKD genes.

Sebastiao APM, Xu B, Lozada JR, Pareja F, Geyer FC, Da Cruz Paula A, da Silva EM, Ghossein RA, Weinreb I, de Noronha L, Weigelt B, Reis-Filho JS, Katabi N.

Mod Pathol. 2019 Sep 6. doi: 10.1038/s41379-019-0351-4. [Epub ahead of print]

PMID:
31492931
4.
5.

Pan-Trk immunohistochemistry is a sensitive and specific ancillary tool in diagnosing secretory carcinoma of salivary gland and detecting ETV6-NTRK3 fusion.

Xu B, Haroon Al Rasheed MR, Antonescu CR, Alex D, Frosina D, Ghossein R, Jungbluth AA, Katabi N.

Histopathology. 2019 Aug 25. doi: 10.1111/his.13981. [Epub ahead of print]

PMID:
31448442
6.

Androgen receptor immunohistochemistry in salivary duct carcinoma: a retrospective study of 188 cases focusing on tumoral heterogeneity and temporal concordance.

Xu B, Dogan S, Haroon Al Rasheed MR, Ghossein R, Katabi N.

Hum Pathol. 2019 Aug 17;93:30-36. doi: 10.1016/j.humpath.2019.08.007. [Epub ahead of print]

PMID:
31430492
7.

Critical Prognostic Parameters in the Anatomic Pathology Reporting of Differentiated Follicular Cell-Derived Thyroid Carcinoma.

Xu B, Ghossein R.

Cancers (Basel). 2019 Aug 2;11(8). pii: E1100. doi: 10.3390/cancers11081100. Review.

8.

The immune microenvironment and expression of PD-L1, PD-1, PRAME and MHC I in salivary duct carcinoma.

Xu B, Jungbluth AA, Frosina D, Alzumaili B, Aleynick N, Slodkowska E, Higgins K, Ho A, Morris L, Ghossein R, Katabi N.

Histopathology. 2019 Nov;75(5):672-682. doi: 10.1111/his.13944. Epub 2019 Oct 2.

PMID:
31237963
9.

Genomic and Transcriptomic Characterization of Papillary Microcarcinomas With Lateral Neck Lymph Node Metastases.

Perera D, Ghossein R, Camacho N, Senbabaoglu Y, Seshan V, Li J, Bouvier N, Boucai L, Viale A, Socci ND, Untch BR, Gonen M, Knauf J, Fagin JA, Berger M, Tuttle RM.

J Clin Endocrinol Metab. 2019 Oct 1;104(10):4889-4899. doi: 10.1210/jc.2019-00431.

PMID:
31237614
10.

DNA methylation-based classification of sinonasal undifferentiated carcinoma.

Dogan S, Vasudevaraja V, Xu B, Serrano J, Ptashkin RN, Jung HJ, Chiang S, Jungbluth AA, Cohen MA, Ganly I, Berger MF, Momeni Boroujeni A, Ghossein RA, Ladanyi M, Chute DJ, Snuderl M.

Mod Pathol. 2019 Oct;32(10):1447-1459. doi: 10.1038/s41379-019-0285-x. Epub 2019 Jun 11.

PMID:
31186531
11.

Phase 2 study of vascular endothelial growth factor trap for the treatment of metastatic thyroid cancer.

Sherman EJ, Dunn LA, Schöder H, Ho AL, Baxi SS, Ghossein RA, Haque SS, Sima C, Tuttle RM, Pfister DG.

Cancer. 2019 Sep 1;125(17):2984-2990. doi: 10.1002/cncr.32046. Epub 2019 Jun 7.

PMID:
31174237
12.

Immunogenic neoantigens derived from gene fusions stimulate T cell responses.

Yang W, Lee KW, Srivastava RM, Kuo F, Krishna C, Chowell D, Makarov V, Hoen D, Dalin MG, Wexler L, Ghossein R, Katabi N, Nadeem Z, Cohen MA, Tian SK, Robine N, Arora K, Geiger H, Agius P, Bouvier N, Huberman K, Vanness K, Havel JJ, Sims JS, Samstein RM, Mandal R, Tepe J, Ganly I, Ho AL, Riaz N, Wong RJ, Shukla N, Chan TA, Morris LGT.

Nat Med. 2019 May;25(5):767-775. doi: 10.1038/s41591-019-0434-2. Epub 2019 Apr 22.

13.

Interobserver Variability in the Histopathologic Assessment of Extrathyroidal Extension of Well Differentiated Thyroid Carcinoma Supports the New American Joint Committee on Cancer Eighth Edition Criteria for Tumor Staging.

Turk AT, Asa SL, Baloch ZW, Faquin WC, Fellegara G, Ghossein RA, Giordano TJ, LiVolsi VA, Lloyd R, Mete O, Rosai J, Suster S, Thompson LDR, Wenig BM.

Thyroid. 2019 May;29(5):619-624. doi: 10.1089/thy.2018.0286. Epub 2019 Apr 27.

PMID:
30913992
14.

Quantitative Non-Gaussian Intravoxel Incoherent Motion Diffusion-Weighted Imaging Metrics and Surgical Pathology for Stratifying Tumor Aggressiveness in Papillary Thyroid Carcinomas.

Núñez DA, Lu Y, Paudyal R, Hatzoglou V, Moreira AL, Oh JH, Stambuk HE, Mazaheri Y, Gonen M, Ghossein RA, Shaha AR, Tuttle RM, Shukla-Dave A.

Tomography. 2019 Mar;5(1):26-35. doi: 10.18383/j.tom.2018.00054.

15.

Misinterpreted Myoepithelial Carcinoma of Salivary Gland: A Challenging and Potentially Significant Pitfall.

Xu B, Mneimneh W, Torrence DE, Higgins K, Klimstra D, Ghossein R, Katabi N.

Am J Surg Pathol. 2019 May;43(5):601-609. doi: 10.1097/PAS.0000000000001218.

PMID:
30789358
16.

Poorly Differentiated Carcinoma of the Thyroid Gland: Current Status and Future Prospects.

Ibrahimpasic T, Ghossein R, Shah JP, Ganly I.

Thyroid. 2019 Mar;29(3):311-321. doi: 10.1089/thy.2018.0509.

PMID:
30747050
17.

Outcome and molecular characteristics of non-invasive encapsulated follicular variant of papillary thyroid carcinoma with oncocytic features.

Xu B, Reznik E, Tuttle RM, Knauf J, Fagin JA, Katabi N, Dogan S, Aleynick N, Seshan V, Middha S, Enepekides D, Casadei GP, Solaroli E, Tallini G, Ghossein R, Ganly I.

Endocrine. 2019 Apr;64(1):97-108. doi: 10.1007/s12020-019-01848-6. Epub 2019 Jan 28.

PMID:
30689169
18.

Interinstitutional variation in predictive value of the ThyroSeq v2 genomic classifier for cytologically indeterminate thyroid nodules.

Marcadis AR, Valderrabano P, Ho AS, Tepe J, Swartzwelder CE, Byrd S, Sacks WL, Untch BR, Shaha AR, Xu B, Lin O, Ghossein RA, Wong RJ, Marti JL, Morris LGT.

Surgery. 2019 Jan;165(1):17-24. doi: 10.1016/j.surg.2018.04.062. Epub 2018 Oct 22.

PMID:
30360906
19.

EIF1AX and RAS Mutations Cooperate to Drive Thyroid Tumorigenesis through ATF4 and c-MYC.

Krishnamoorthy GP, Davidson NR, Leach SD, Zhao Z, Lowe SW, Lee G, Landa I, Nagarajah J, Saqcena M, Singh K, Wendel HG, Dogan S, Tamarapu PP, Blenis J, Ghossein RA, Knauf JA, Rätsch G, Fagin JA.

Cancer Discov. 2019 Feb;9(2):264-281. doi: 10.1158/2159-8290.CD-18-0606. Epub 2018 Oct 10.

PMID:
30305285
20.

Vemurafenib Redifferentiation of BRAF Mutant, RAI-Refractory Thyroid Cancers.

Dunn LA, Sherman EJ, Baxi SS, Tchekmedyian V, Grewal RK, Larson SM, Pentlow KS, Haque S, Tuttle RM, Sabra MM, Fish S, Boucai L, Walters J, Ghossein RA, Seshan VE, Ni A, Li D, Knauf JA, Pfister DG, Fagin JA, Ho AL.

J Clin Endocrinol Metab. 2019 May 1;104(5):1417-1428. doi: 10.1210/jc.2018-01478.

21.

The role of a monoclonal antibody 11C8B1 as a diagnostic marker of IDH2-mutated sinonasal undifferentiated carcinoma.

Dogan S, Frosina D, Fayad M, de Oliveira TB, Alemar B, Rosenblum M, Tang LH, Hameed M, Xu B, Ghossein RA, Chute DJ, Weigelt B, Jungbluth AA.

Mod Pathol. 2019 Feb;32(2):205-215. doi: 10.1038/s41379-018-0126-3. Epub 2018 Sep 11.

PMID:
30206411
22.

Integrated Genomic Analysis of Hürthle Cell Cancer Reveals Oncogenic Drivers, Recurrent Mitochondrial Mutations, and Unique Chromosomal Landscapes.

Ganly I, Makarov V, Deraje S, Dong Y, Reznik E, Seshan V, Nanjangud G, Eng S, Bose P, Kuo F, Morris LGT, Landa I, Carrillo Albornoz PB, Riaz N, Nikiforov YE, Patel K, Umbricht C, Zeiger M, Kebebew E, Sherman E, Ghossein R, Fagin JA, Chan TA.

Cancer Cell. 2018 Aug 13;34(2):256-270.e5. doi: 10.1016/j.ccell.2018.07.002.

23.
24.

Ameloblastomas of the mandible and maxilla.

Petrovic ID, Migliacci J, Ganly I, Patel S, Xu B, Ghossein R, Huryn J, Shah J.

Ear Nose Throat J. 2018 Jul;97(7):E26-E32.

25.

Hgf/Met activation mediates resistance to BRAF inhibition in murine anaplastic thyroid cancers.

Knauf JA, Luckett KA, Chen KY, Voza F, Socci ND, Ghossein R, Fagin JA.

J Clin Invest. 2018 Aug 31;128(9):4086-4097. doi: 10.1172/JCI120966. Epub 2018 Aug 20.

26.

Performance of a Genomic Sequencing Classifier for the Preoperative Diagnosis of Cytologically Indeterminate Thyroid Nodules.

Patel KN, Angell TE, Babiarz J, Barth NM, Blevins T, Duh QY, Ghossein RA, Harrell RM, Huang J, Kennedy GC, Kim SY, Kloos RT, LiVolsi VA, Randolph GW, Sadow PM, Shanik MH, Sosa JA, Traweek ST, Walsh PS, Whitney D, Yeh MW, Ladenson PW.

JAMA Surg. 2018 Sep 1;153(9):817-824. doi: 10.1001/jamasurg.2018.1153.

27.

Tipifarnib Inhibits HRAS-Driven Dedifferentiated Thyroid Cancers.

Untch BR, Dos Anjos V, Garcia-Rendueles MER, Knauf JA, Krishnamoorthy GP, Saqcena M, Bhanot UK, Socci ND, Ho AL, Ghossein R, Fagin JA.

Cancer Res. 2018 Aug 15;78(16):4642-4657. doi: 10.1158/0008-5472.CAN-17-1925. Epub 2018 May 14.

28.

Patterns of recurrence in oral tongue cancer with perineural invasion.

Cracchiolo JR, Xu B, Migliacci JC, Katabi N, Pfister DG, Lee NY, Patel SG, Ghossein RA, Wong RJ.

Head Neck. 2018 Jun;40(6):1287-1295. doi: 10.1002/hed.25110. Epub 2018 Mar 9.

29.

The evolving diagnosis of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP).

Lloyd RV, Asa SL, LiVolsi VA, Sadow PM, Tischler AS, Ghossein RA, Tuttle RM, Nikiforov YE.

Hum Pathol. 2018 Apr;74:1-4. doi: 10.1016/j.humpath.2017.12.027. Epub 2018 Jan 16. No abstract available.

PMID:
29339178
30.

Solitary Extramedullary Plasmacytoma of the Cricoid Cartilage-Case Report.

Krebs S, Ganly I, Ghossein R, Yang J, Yahalom J, Schöder H.

Front Oncol. 2017 Nov 27;7:284. doi: 10.3389/fonc.2017.00284. eCollection 2017.

31.

Should subcentimeter non-invasive encapsulated, follicular variant of papillary thyroid carcinoma be included in the noninvasive follicular thyroid neoplasm with papillary-like nuclear features category?

Xu B, Farhat N, Barletta JA, Hung YP, Biase D, Casadei GP, Onenerk AM, Tuttle RM, Roman BR, Katabi N, Nosé V, Sadow P, Tallini G, Faquin WC, Ghossein R.

Endocrine. 2018 Jan;59(1):143-150. doi: 10.1007/s12020-017-1484-1. Epub 2017 Dec 4.

32.

Multi-dimensional genomic analysis of myoepithelial carcinoma identifies prevalent oncogenic gene fusions.

Dalin MG, Katabi N, Persson M, Lee KW, Makarov V, Desrichard A, Walsh LA, West L, Nadeem Z, Ramaswami D, Havel JJ, Kuo F, Chadalavada K, Nanjangud GJ, Ganly I, Riaz N, Ho AL, Antonescu CR, Ghossein R, Stenman G, Chan TA, Morris LGT.

Nat Commun. 2017 Oct 30;8(1):1197. doi: 10.1038/s41467-017-01178-z.

33.

Pathologic Reporting of Tall-Cell Variant of Papillary Thyroid Cancer: Have We Reached a Consensus?

Hernandez-Prera JC, Machado RA, Asa SL, Baloch Z, Faquin WC, Ghossein R, LiVolsi VA, Lloyd RV, Mete O, Nikiforov YE, Seethala RR, Suster S, Thompson LD, Turk AT, Sadow PM, Urken ML, Wenig BM.

Thyroid. 2017 Dec;27(12):1498-1504. doi: 10.1089/thy.2017.0280. Epub 2017 Nov 7.

PMID:
29020884
34.

PD-1 Expression in Head and Neck Squamous Cell Carcinomas Derives Primarily from Functionally Anergic CD4+ TILs in the Presence of PD-L1+ TAMs.

Mattox AK, Lee J, Westra WH, Pierce RH, Ghossein R, Faquin WC, Diefenbach TJ, Morris LG, Lin DT, Wirth LJ, Lefranc-Torres A, Ishida E, Chakravarty PD, Johnson L, Zeng YC, Chen H, Poznansky MC, Iyengar NM, Pai SI.

Cancer Res. 2017 Nov 15;77(22):6365-6374. doi: 10.1158/0008-5472.CAN-16-3453. Epub 2017 Sep 25.

35.

Natural History and Tumor Volume Kinetics of Papillary Thyroid Cancers During Active Surveillance.

Tuttle RM, Fagin JA, Minkowitz G, Wong RJ, Roman B, Patel S, Untch B, Ganly I, Shaha AR, Shah JP, Pace M, Li D, Bach A, Lin O, Whiting A, Ghossein R, Landa I, Sabra M, Boucai L, Fish S, Morris LGT.

JAMA Otolaryngol Head Neck Surg. 2017 Oct 1;143(10):1015-1020. doi: 10.1001/jamaoto.2017.1442.

36.

PLAG1 immunohistochemistry is a sensitive marker for pleomorphic adenoma: a comparative study with PLAG1 genetic abnormalities.

Katabi N, Xu B, Jungbluth AA, Zhang L, Shao SY, Lane J, Ghossein R, Antonescu CR.

Histopathology. 2018 Jan;72(2):285-293. doi: 10.1111/his.13341. Epub 2017 Oct 19.

37.

Crucial parameters in thyroid carcinoma reporting - challenges, controversies and clinical implications.

Xu B, Ghossein RA.

Histopathology. 2018 Jan;72(1):32-39. doi: 10.1111/his.13335. Review.

38.

Salivary gland epithelial neoplasms in pediatric population: a single-institute experience with a focus on the histologic spectrum and clinical outcome.

Xu B, Aneja A, Ghossein R, Katabi N.

Hum Pathol. 2017 Sep;67:37-44. doi: 10.1016/j.humpath.2017.07.007. Epub 2017 Jul 21.

PMID:
28739497
39.

Predictors of Outcome in Adenoid Cystic Carcinoma of Salivary Glands: A Clinicopathologic Study With Correlation Between MYB Fusion and Protein Expression.

Xu B, Drill E, Ho A, Ho A, Dunn L, Prieto-Granada CN, Chan T, Ganly I, Ghossein R, Katabi N.

Am J Surg Pathol. 2017 Oct;41(10):1422-1432. doi: 10.1097/PAS.0000000000000918.

40.

Phase 2 study evaluating the combination of sorafenib and temsirolimus in the treatment of radioactive iodine-refractory thyroid cancer.

Sherman EJ, Dunn LA, Ho AL, Baxi SS, Ghossein RA, Fury MG, Haque S, Sima CS, Cullen G, Fagin JA, Pfister DG.

Cancer. 2017 Nov 1;123(21):4114-4121. doi: 10.1002/cncr.30861. Epub 2017 Jun 29.

41.

Genomic Alterations in Fatal Forms of Non-Anaplastic Thyroid Cancer: Identification of MED12 and RBM10 as Novel Thyroid Cancer Genes Associated with Tumor Virulence.

Ibrahimpasic T, Xu B, Landa I, Dogan S, Middha S, Seshan V, Deraje S, Carlson DL, Migliacci J, Knauf JA, Untch B, Berger MF, Morris L, Tuttle RM, Chan T, Fagin JA, Ghossein R, Ganly I.

Clin Cancer Res. 2017 Oct 1;23(19):5970-5980. doi: 10.1158/1078-0432.CCR-17-1183. Epub 2017 Jun 20.

42.

Patients with Multifocal Macroscopic Papillary Thyroid Carcinoma Have a Low Risk of Recurrence at Early Follow-Up after Total Thyroidectomy and Radioactive Iodine Treatment.

La Greca A, Xu B, Ghossein R, Tuttle RM, Sabra MM.

Eur Thyroid J. 2017 Feb;6(1):31-39. doi: 10.1159/000448752. Epub 2016 Oct 4.

43.

Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene.

Montero-Conde C, Leandro-Garcia LJ, Chen X, Oler G, Ruiz-Llorente S, Ryder M, Landa I, Sanchez-Vega F, La K, Ghossein RA, Bajorin DF, Knauf JA, Riordan JD, Dupuy AJ, Fagin JA.

Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):E4951-E4960. doi: 10.1073/pnas.1702723114. Epub 2017 Jun 5.

44.

Evolution of the histologic classification of thyroid neoplasms and its impact on clinical management.

Xu B, Ghossein R.

Eur J Surg Oncol. 2018 Mar;44(3):338-347. doi: 10.1016/j.ejso.2017.05.002. Epub 2017 May 18. Review.

45.

Metastatic thyroid carcinoma without identifiable primary tumor within the thyroid gland: a retrospective study of a rare phenomenon.

Xu B, Scognamiglio T, Cohen PR, Prasad ML, Hasanovic A, Tuttle RM, Katabi N, Ghossein RA.

Hum Pathol. 2017 Jul;65:133-139. doi: 10.1016/j.humpath.2017.05.013. Epub 2017 May 25.

46.

Frequent IDH2 R172 mutations in undifferentiated and poorly-differentiated sinonasal carcinomas.

Dogan S, Chute DJ, Xu B, Ptashkin RN, Chandramohan R, Casanova-Murphy J, Nafa K, Bishop JA, Chiosea SI, Stelow EB, Ganly I, Pfister DG, Katabi N, Ghossein RA, Berger MF.

J Pathol. 2017 Aug;242(4):400-408. doi: 10.1002/path.4915. Epub 2017 Jun 9.

47.

Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features: Historical Context, Diagnosis, and Future Challenges.

Xu B, Tallini G, Ghossein RA.

Endocr Pathol. 2017 Jun;28(2):128-138. doi: 10.1007/s12022-017-9478-3. Review. Retraction in: Endocr Pathol. 2018 Aug 7;:.

PMID:
28361392
48.

A Proposal to Redefine Close Surgical Margins in Squamous Cell Carcinoma of the Oral Tongue.

Zanoni DK, Migliacci JC, Xu B, Katabi N, Montero PH, Ganly I, Shah JP, Wong RJ, Ghossein RA, Patel SG.

JAMA Otolaryngol Head Neck Surg. 2017 Jun 1;143(6):555-560. doi: 10.1001/jamaoto.2016.4238.

49.

Outcome of Large Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features.

Xu B, Tallini G, Scognamiglio T, Roman BR, Tuttle RM, Ghossein RA.

Thyroid. 2017 Apr;27(4):512-517. doi: 10.1089/thy.2016.0649. Epub 2017 Feb 24.

50.

Primary Thyroid Carcinoma with Low-Risk Histology and Distant Metastases: Clinicopathologic and Molecular Characteristics.

Xu B, Tuttle RM, Sabra MM, Ganly I, Ghossein R.

Thyroid. 2017 May;27(5):632-640. doi: 10.1089/thy.2016.0582. Epub 2017 Feb 1.

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