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Items: 33


Hematopoietic stem cell-independent hematopoiesis and the origins of innate-like B lymphocytes.

Ghosn E, Yoshimoto M, Nakauchi H, Weissman IL, Herzenberg LA.

Development. 2019 Aug 1;146(15). pii: dev170571. doi: 10.1242/dev.170571. Review.


Automated subset identification and characterization pipeline for multidimensional flow and mass cytometry data clustering and visualization.

Meehan S, Kolyagin GA, Parks D, Youngyunpipatkul J, Herzenberg LA, Walther G, Ghosn EEB, Orlova DY.

Commun Biol. 2019 Jun 20;2:229. doi: 10.1038/s42003-019-0467-6. eCollection 2019.


B1 B cell progenitors.

Ghosn E, Dorshkind K, Herzenberg LA, Holodick N, Kantor A, Montecino-Rodriguez E, Rothstein TL, Silverman GJ, Yang Y, Yoder MC, Yoshimoto M.

Science. 2019 Apr 19;364(6437):248. doi: 10.1126/science.aax6784. Epub 2019 Apr 18. No abstract available.


QFMatch: multidimensional flow and mass cytometry samples alignment.

Orlova DY, Meehan S, Parks D, Moore WA, Meehan C, Zhao Q, Ghosn EEB, Herzenberg LA, Walther G.

Sci Rep. 2018 Feb 19;8(1):3291. doi: 10.1038/s41598-018-21444-4.


Evidence for altered levels of IgD in the nasal airway mucosa of patients with chronic rhinosinusitis.

Min JY, Nayak JV, Hulse KE, Stevens WW, Raju PA, Huang JH, Suh LA, Van Roey GA, Norton JE, Carter RG, Price CPE, Weibman AR, Rashan AR, Ghosn EE, Patel ZM, Homma T, Conley DB, Welch KC, Shintani-Smith S, Peters AT, Grammer LC 3rd, Harris KE, Kato A, Hwang PH, Kern RC, Herzenberg LA, Schleimer RP, Tan BK.

J Allergy Clin Immunol. 2017 Dec;140(6):1562-1571.e5. doi: 10.1016/j.jaci.2017.05.032. Epub 2017 Jun 16.


A new family with an SLC9A6 mutation expanding the phenotypic spectrum of Christianson syndrome.

Masurel-Paulet A, Piton A, Chancenotte S, Redin C, Thauvin-Robinet C, Henrenger Y, Minot D, Creppy A, Ruffier-Bourdet M, Thevenon J, Kuentz P, Lehalle D, Curie A, Blanchard G, Ghosn E, Bonnet M, Archimbaud-Devilliers M, Huet F, Perret O, Philip N, Mandel JL, Faivre L.

Am J Med Genet A. 2016 Aug;170(8):2103-10. doi: 10.1002/ajmg.a.37765. Epub 2016 Jun 3.


Earth Mover's Distance (EMD): A True Metric for Comparing Biomarker Expression Levels in Cell Populations.

Orlova DY, Zimmerman N, Meehan S, Meehan C, Waters J, Ghosn EE, Filatenkov A, Kolyagin GA, Gernez Y, Tsuda S, Moore W, Moss RB, Herzenberg LA, Walther G.

PLoS One. 2016 Mar 23;11(3):e0151859. doi: 10.1371/journal.pone.0151859. eCollection 2016.


Fetal Hematopoietic Stem Cell Transplantation Fails to Fully Regenerate the B-Lymphocyte Compartment.

Ghosn EE, Waters J, Phillips M, Yamamoto R, Long BR, Yang Y, Gerstein R, Stoddart CA, Nakauchi H, Herzenberg LA.

Stem Cell Reports. 2016 Jan 12;6(1):137-49. doi: 10.1016/j.stemcr.2015.11.011. Epub 2015 Dec 24.


B-1 Cell Development and Function.

Rothstein TL, Herzenberg LA, Holodick NE, Ghosn E.

Ann N Y Acad Sci. 2015 Dec;1362:v-vi. doi: 10.1111/nyas.12949. No abstract available.


Hematopoietic stem cell-independent B-1a lineage.

Ghosn EE, Yang Y.

Ann N Y Acad Sci. 2015 Dec;1362:23-38. doi: 10.1111/nyas.12881. Review.


Amyloid fibrils activate B-1a lymphocytes to ameliorate inflammatory brain disease.

Kurnellas MP, Ghosn EE, Schartner JM, Baker J, Rothbard JJ, Negrin RS, Herzenberg LA, Fathman CG, Steinman L, Rothbard JB.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15016-23. doi: 10.1073/pnas.1521206112. Epub 2015 Nov 30.


Is percutaneous proximal gracilis tenotomy as effective and safe as the open procedure?

Hachache B, Eid T, Ghosn E, Sebaaly A, Kharrat K, Ghanem I.

J Child Orthop. 2015 Dec;9(6):477-81. doi: 10.1007/s11832-015-0699-z. Epub 2015 Oct 26.


Distinct mechanisms define murine B cell lineage immunoglobulin heavy chain (IgH) repertoires.

Yang Y, Wang C, Yang Q, Kantor AB, Chu H, Ghosn EE, Qin G, Mazmanian SK, Han J, Herzenberg LA.

Elife. 2015 Sep 30;4:e09083. doi: 10.7554/eLife.09083.


AutoGate: automating analysis of flow cytometry data.

Meehan S, Walther G, Moore W, Orlova D, Meehan C, Parks D, Ghosn E, Philips M, Mitsunaga E, Waters J, Kantor A, Okamura R, Owumi S, Yang Y, Herzenberg LA, Herzenberg LA.

Immunol Res. 2014 May;58(2-3):218-23. doi: 10.1007/s12026-014-8519-y.


Selective uptake of single-walled carbon nanotubes by circulating monocytes for enhanced tumour delivery.

Smith BR, Ghosn EE, Rallapalli H, Prescher JA, Larson T, Herzenberg LA, Gambhir SS.

Nat Nanotechnol. 2014 Jun;9(6):481-7. doi: 10.1038/nnano.2014.62. Epub 2014 Apr 13.


Determination of HPV prevalence in oral/oropharyngeal mucosa samples in a rural district of São Paulo.

Cavenaghi VB, Ghosn EJ, Cruz N, Rossi LM, da Silva L, Costa HO, Villa LL.

Braz J Otorhinolaryngol. 2013 Sep-Oct;79(5):599-602. doi: 10.5935/1808-8694.20130107. English, Portuguese.


Intracellular localization of myeloperoxidase in murine peritoneal B-lymphocytes and macrophages.

de Araujo TH, Okada SS, Ghosn EE, Taniwaki NN, Rodrigues MR, de Almeida SR, Mortara RA, Russo M, Campa A, Albuquerque RC.

Cell Immunol. 2013 Jan;281(1):27-30. doi: 10.1016/j.cellimm.2013.01.002. Epub 2013 Jan 29.


Reversal of paralysis and reduced inflammation from peripheral administration of β-amyloid in TH1 and TH17 versions of experimental autoimmune encephalomyelitis.

Grant JL, Ghosn EE, Axtell RC, Herges K, Kuipers HF, Woodling NS, Andreasson K, Herzenberg LA, Herzenberg LA, Steinman L.

Sci Transl Med. 2012 Aug 1;4(145):145ra105. doi: 10.1126/scitranslmed.3004145.


Development of B cells and erythrocytes is specifically impaired by the drug celastrol in mice.

Kusy S, Ghosn EE, Herzenberg LA, Contag CH.

PLoS One. 2012;7(4):e35733. doi: 10.1371/journal.pone.0035733. Epub 2012 Apr 24.


Distinct B-cell lineage commitment distinguishes adult bone marrow hematopoietic stem cells.

Ghosn EE, Yamamoto R, Hamanaka S, Yang Y, Herzenberg LA, Nakauchi H, Herzenberg LA.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5394-8. doi: 10.1073/pnas.1121632109. Epub 2012 Mar 19.


Antigen-specific memory in B-1a and its relationship to natural immunity.

Yang Y, Ghosn EE, Cole LE, Obukhanych TV, Sadate-Ngatchou P, Vogel SN, Herzenberg LA, Herzenberg LA.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5388-93. doi: 10.1073/pnas.1121627109. Epub 2012 Mar 14.


Antigen-specific antibody responses in B-1a and their relationship to natural immunity.

Yang Y, Ghosn EE, Cole LE, Obukhanych TV, Sadate-Ngatchou P, Vogel SN, Herzenberg LA, Herzenberg LA.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5382-7. doi: 10.1073/pnas.1121631109. Epub 2012 Mar 14.


Cellular renewal and improvement of local cell effector activity in peritoneal cavity in response to infectious stimuli.

Cassado Ados A, de Albuquerque JA, Sardinha LR, Buzzo Cde L, Faustino L, Nascimento R, Ghosn EE, Lima MR, Alvarez JM, Bortoluci KR.

PLoS One. 2011;6(7):e22141. doi: 10.1371/journal.pone.0022141. Epub 2011 Jul 22.


Distinct progenitors for B-1 and B-2 cells are present in adult mouse spleen.

Ghosn EE, Sadate-Ngatchou P, Yang Y, Herzenberg LA, Herzenberg LA.

Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2879-84. doi: 10.1073/pnas.1019764108. Epub 2011 Jan 31.


Basophil CD203c levels are increased at baseline and can be used to monitor omalizumab treatment in subjects with nut allergy.

Gernez Y, Tirouvanziam R, Yu G, Ghosn EE, Reshamwala N, Nguyen T, Tsai M, Galli SJ, Herzenberg LA, Herzenberg LA, Nadeau KC.

Int Arch Allergy Immunol. 2011;154(4):318-27. doi: 10.1159/000321824. Epub 2010 Oct 25.


Two physically, functionally, and developmentally distinct peritoneal macrophage subsets.

Ghosn EE, Cassado AA, Govoni GR, Fukuhara T, Yang Y, Monack DM, Bortoluci KR, Almeida SR, Herzenberg LA, Herzenberg LA.

Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2568-73. doi: 10.1073/pnas.0915000107. Epub 2010 Jan 25.


Monocyte-derived dendritic cells from patients with severe forms of chromoblastomycosis induce CD4+ T cell activation in vitro.

Sousa MG, Ghosn EE, Nascimento RC, Bomfim GF, Noal V, Santiago K, de Maria Pedrozo E Silva Azevedo C, Marques SG, Gonçalves AG, de Castro Lima Santos DW, Criado PR, Costa Martins JE, Almeida SR.

Clin Exp Immunol. 2009 Apr;156(1):117-25. doi: 10.1111/j.1365-2249.2008.03870.x. Epub 2009 Feb 4.


Fonsecaea pedrosoi infection induces differential modulation of costimulatory molecules and cytokines in monocytes from patients with severe and mild forms of chromoblastomycosis.

Sousa MG, de Maria Pedrozo e Silva Azevedo C, Nascimento RC, Ghosn EE, Santiago KL, Noal V, Bomfim GF, Marques SG, Gonçalves AG, Wagner de Castro Lima Santos D, Almeida SR.

J Leukoc Biol. 2008 Sep;84(3):864-70. doi: 10.1189/jlb.0308211. Epub 2008 Jun 18.


CD11b expression distinguishes sequential stages of peritoneal B-1 development.

Ghosn EE, Yang Y, Tung J, Herzenberg LA, Herzenberg LA.

Proc Natl Acad Sci U S A. 2008 Apr 1;105(13):5195-200. doi: 10.1073/pnas.0712350105. Epub 2008 Mar 28.


Division and differentiation of natural antibody-producing cells in mouse spleen.

Yang Y, Tung JW, Ghosn EE, Herzenberg LA, Herzenberg LA.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4542-6. Epub 2007 Mar 7.


Absence of CD4+ T cells impairs host defence of mice infected with Fonsecaea pedrosoi.

Teixeira de Sousa Mda G, Ghosn EE, Almeida SR.

Scand J Immunol. 2006 Dec;64(6):595-600.


Nitric oxide-dependent killing of Cryptococcus neoformans by B-1-derived mononuclear phagocyte.

Ghosn EE, Russo M, Almeida SR.

J Leukoc Biol. 2006 Jul;80(1):36-44. Epub 2006 May 2.


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