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Items: 1 to 50 of 103


HIV-1 Nef-GCC185 interaction regulates assembly of cellular protein complexes at TGN targeting MHC-I downregulation.

Kumari S, Kumar M, Verma R, Ghosh JK, Tripathi RK.

Life Sci. 2019 Jul 15;229:13-20. doi: 10.1016/j.lfs.2019.04.008. Epub 2019 Apr 3.


HIV-1 Nef physically associate with CAMKIIδ - ASK-1 complex to inhibit p38MAPK signalling and apoptosis in infected cells.

Kumar P, Rawat K, Sharma T, Kumari S, Saxena R, Kumar B, Baghel T, Afshan T, Siddiqi MI, Nazir A, Ghosh JK, Tripathi RK.

Life Sci. 2019 May 1;224:263-273. doi: 10.1016/j.lfs.2019.03.039. Epub 2019 Mar 19.


Liquid chromatography-tandem mass spectrometry based method development and validation of S016-1271 (LR8P), a novel cationic antimicrobial peptide for its application to pharmacokinetic studies.

Puttrevu SK, Laxman TS, Tripathi AK, Yadav AK, Verma SK, Mishra A, Pradhan R, Verma NK, Ghosh JK, Bhatta RS.

J Pharm Biomed Anal. 2019 May 30;169:116-126. doi: 10.1016/j.jpba.2019.01.046. Epub 2019 Feb 19.


Challenges and solutions to estimating tuberculosis disease incidence by country of birth in Los Angeles County.

Readhead A, Chang AH, Ghosh JK, Sorvillo F, Detels R, Higashi J.

PLoS One. 2018 Dec 18;13(12):e0209051. doi: 10.1371/journal.pone.0209051. eCollection 2018.


Cell-Selective Pore Forming Antimicrobial Peptides of the Prodomain of Human Furin: A Conserved Aromatic/Cationic Sequence Mapping, Membrane Disruption, and Atomic-Resolution Structure and Dynamics.

Sinha S, Harioudh MK, Dewangan RP, Ng WJ, Ghosh JK, Bhattacharjya S.

ACS Omega. 2018 Nov 30;3(11):14650-14664. doi: 10.1021/acsomega.8b01876. Epub 2018 Nov 1.


A TLR4-derived non-cytotoxic, self-assembling peptide functions as a vaccine adjuvant in mice.

Tandon A, Pathak M, Harioudh MK, Ahmad S, Sayeed M, Afshan T, Siddiqi MI, Mitra K, Bhattacharya SM, Ghosh JK.

J Biol Chem. 2018 Dec 21;293(51):19874-19885. doi: 10.1074/jbc.RA118.002768. Epub 2018 Nov 1.


A collagen domain-derived short adiponectin peptide activates APPL1 and AMPK signaling pathways and improves glucose and fatty acid metabolisms.

Sayeed M, Gautam S, Verma DP, Afshan T, Kumari T, Srivastava AK, Ghosh JK.

J Biol Chem. 2018 Aug 31;293(35):13509-13523. doi: 10.1074/jbc.RA118.001801. Epub 2018 Jul 10.


HIV-1 Nef CAWLEAQ motif: a regulator of monocytes invasion through ENO1 modulation.

Saxena R, Vekariya UK, Kumar P, Tripathi AK, Ghosh JK, Tripathi RK.

Mol Cell Biochem. 2018 Oct;447(1-2):151-164. doi: 10.1007/s11010-018-3300-5. Epub 2018 Feb 5.


An MD2-derived peptide promotes LPS aggregation, facilitates its internalization in THP-1 cells, and inhibits LPS-induced pro-inflammatory responses.

Tandon A, Harioudh MK, Ishrat N, Tripathi AK, Srivastava S, Ghosh JK.

Cell Mol Life Sci. 2018 Jul;75(13):2431-2446. doi: 10.1007/s00018-017-2735-2. Epub 2018 Jan 8.


A short non-cytotoxic antimicrobial peptide designed from Aβ29-40 adopts a nanostructure and shows in vivo anti-endotoxin activity.

Harioudh MK, Sahai R, Mitra K, Ghosh JK.

Chem Commun (Camb). 2017 Dec 5;53(97):13079-13082. doi: 10.1039/c7cc07547b.


Molecular Dynamics Simulations of the Host Defense Peptide Temporin L and Its Q3K Derivative: An Atomic Level View from Aggregation in Water to Bilayer Perturbation.

Farrotti A, Conflitti P, Srivastava S, Ghosh JK, Palleschi A, Stella L, Bocchinfuso G.

Molecules. 2017 Jul 22;22(7). pii: E1235. doi: 10.3390/molecules22071235.


Identification of GXXXXG motif in Chrysophsin-1 and its implication in the design of analogs with cell-selective antimicrobial and anti-endotoxin activities.

Tripathi AK, Kumari T, Harioudh MK, Yadav PK, Kathuria M, Shukla PK, Mitra K, Ghosh JK.

Sci Rep. 2017 Jun 13;7(1):3384. doi: 10.1038/s41598-017-03576-1.


Selective phenylalanine to proline substitution for improved antimicrobial and anticancer activities of peptides designed on phenylalanine heptad repeat.

Tripathi AK, Kumari T, Tandon A, Sayeed M, Afshan T, Kathuria M, Shukla PK, Mitra K, Ghosh JK.

Acta Biomater. 2017 Jul 15;57:170-186. doi: 10.1016/j.actbio.2017.05.007. Epub 2017 May 5.


Spermicidal efficacy of VRP, a synthetic cationic antimicrobial peptide, inducing apoptosis and membrane disruption.

Ghosh P, Bhoumik A, Saha S, Mukherjee S, Azmi S, Ghosh JK, Dungdung SR.

J Cell Physiol. 2018 Feb;233(2):1041-1050. doi: 10.1002/jcp.25958. Epub 2017 Jun 6.


Piscidin-1-analogs with double L- and D-lysine residues exhibited different conformations in lipopolysaccharide but comparable anti-endotoxin activities.

Kumar A, Mahajan M, Awasthi B, Tandon A, Harioudh MK, Shree S, Singh P, Shukla PK, Ramachandran R, Mitra K, Bhattacharjya S, Ghosh JK.

Sci Rep. 2017 Jan 4;7:39925. doi: 10.1038/srep39925.


Modulation of anti-endotoxin property of Temporin L by minor amino acid substitution in identified phenylalanine zipper sequence.

Srivastava S, Kumar A, Tripathi AK, Tandon A, Ghosh JK.

Biochem J. 2016 Nov 1;473(21):4045-4062. Epub 2016 Sep 8.


Efficacy of aspiration in amebic liver abscess.

Ghosh JK, Goyal SK, Behera MK, Tripathi MK, Dixit VK, Jain AK, Shukla R.

Trop Gastroenterol. 2015 Oct-Dec;36(4):251-5.


Solitary rectal ulcer syndrome: clinical, endoscopic, histological and anorectal manometry findings in north Indian patients.

Behera MK, Dixit VK, Shukla SK, Ghosh JK, Abhilash VB, Asati PK, Jain AK.

Trop Gastroenterol. 2015 Oct-Dec;36(4):244-50.


Isoniazid therapy for Mycobacterium tuberculosis infection in HIV clinics, Los Angeles, California.

Shin SS, Chang AH, Ghosh JK, Dubé MP, Bolan R, Yang OO, Kerndt PR.

Int J Tuberc Lung Dis. 2016 Jul;20(7):961-6. doi: 10.5588/ijtld.15.0988.


Synergistic effects of air pollution and psychosocial stressors on adolescent lung function.

Bandoli G, von Ehrenstein O, Ghosh JK, Ritz B.

J Allergy Clin Immunol. 2016 Sep;138(3):918-920.e4. doi: 10.1016/j.jaci.2016.04.012. Epub 2016 Apr 30. No abstract available.


Psychosocial stressors and lung function in youth ages 10-17: an examination by stressor, age and gender.

Bandoli G, Ghosh JK, von Ehrenstein O, Ritz B.

J Public Health (Oxf). 2017 Jun 1;39(2):297-303. doi: 10.1093/pubmed/fdw035.


Single Amino Acid Substitutions at Specific Positions of the Heptad Repeat Sequence of Piscidin-1 Yielded Novel Analogs That Show Low Cytotoxicity and In Vitro and In Vivo Antiendotoxin Activity.

Kumar A, Tripathi AK, Kathuria M, Shree S, Tripathi JK, Purshottam RK, Ramachandran R, Mitra K, Ghosh JK.

Antimicrob Agents Chemother. 2016 May 23;60(6):3687-99. doi: 10.1128/AAC.02341-15. Print 2016 Jun.


Multi-pollutant exposure profiles associated with term low birth weight in Los Angeles County.

Coker E, Liverani S, Ghosh JK, Jerrett M, Beckerman B, Li A, Ritz B, Molitor J.

Environ Int. 2016 May;91:1-13. doi: 10.1016/j.envint.2016.02.011. Epub 2016 Feb 15.


Duplication of transverse colon in an adult presenting as chronic diarrhea.

Ghosh JK, Goyal SK, Behera MK, Abhilash VB, Dixit VK, Jain AK.

Trop Gastroenterol. 2015 Jan-Mar;36(1):62-3. No abstract available.


Colonic spirochetosis in an immunocompetent child.

Ghosh JK, Goyal SK, Lamtha SC, Kaushik P, Behera MK, Abhilash VB, Dixit VK, Jain AK.

Trop Gastroenterol. 2014 Oct-Dec;35(4):266-9. No abstract available.


Prenatal Maternal Stress and the Risk of Lifetime Wheeze in Young Offspring: An Examination by Stressor and Maternal Ethnicity.

Bandoli G, von Ehrenstein O, Ghosh JK, Flores ME, Dunkel Schetter C, Ritz B.

J Immigr Minor Health. 2016 Oct;18(5):987-95. doi: 10.1007/s10903-015-0269-y.


Tetrahydrofuran amino acid-containing gramicidin S analogues with improved biological profiles.

Pal S, Singh G, Singh S, Tripathi JK, Ghosh JK, Sinha S, Ampapathi RS, Chakraborty TK.

Org Biomol Chem. 2015 Jun 28;13(24):6789-802. doi: 10.1039/c5ob00622h.


Efficacy of liquid-based cytology versus conventional smears in FNA samples.

Tripathy K, Misra A, Ghosh JK.

J Cytol. 2015 Jan-Mar;32(1):17-20. doi: 10.4103/0970-9371.155225.


Variants of self-assembling peptide, KLD-12 that show both rapid fracture healing and antimicrobial properties.

Tripathi JK, Pal S, Awasthi B, Kumar A, Tandon A, Mitra K, Chattopadhyay N, Ghosh JK.

Biomaterials. 2015 Jul;56:92-103. doi: 10.1016/j.biomaterials.2015.03.046. Epub 2015 Apr 16.


Hydatid Cyst of Liver Presented as Obstructive Jaundice in Pregnancy; Managed by PAIR.

Ghosh JK, Goyal SK, Behera MK, Dixit VK, Jain AK.

J Clin Exp Hepatol. 2014 Dec;4(4):366-9. doi: 10.1016/j.jceh.2014.11.002. Epub 2014 Nov 26.


Clinical Profile and Response to Treatment with Pegylated Interferon α 2b and Ribavirin in Chronic Hepatitis C-A Reappraisal from a Tertiary Care Center in Northern India.

Dixit VK, Ghosh JK, Lamtha SC, Kaushik P, Goyal SK, Behera MK, Singh N, Jain AK.

J Clin Exp Hepatol. 2014 Jun;4(2):101-5. doi: 10.1016/j.jceh.2014.05.012. Epub 2014 Jun 18.


Assessment of the Model for End-stage Liver Disease (MELD) Score in Predicting Prognosis of Patients with Alcoholic Hepatitis.

Goyal SK, Dixit VK, Jain AK, Mohapatra PK, Ghosh JK.

J Clin Exp Hepatol. 2014 Mar;4(1):19-24. doi: 10.1016/j.jceh.2014.02.006. Epub 2014 Feb 27.


Design and characterization of short antimicrobial peptides using leucine zipper templates with selectivity towards microorganisms.

Ahmad A, Azmi S, Srivastava S, Kumar A, Tripathi JK, Mishra NN, Shukla PK, Ghosh JK.

Amino Acids. 2014 Nov;46(11):2531-43. doi: 10.1007/s00726-014-1802-3. Epub 2014 Jul 29.


Four cases of adenocarcinoma of esophagus with co-existing hydatid cyst of liver which caused delayed management of carcinoma esophagus.

Ghosh JK, Goyal SK, Dixit VK, Jain AK.

Indian J Gastroenterol. 2015 Jan;34(1):84-5. doi: 10.1007/s12664-014-0480-0. No abstract available.


Prenatal exposure to traffic-related air pollution and risk of early childhood cancers.

Ghosh JK, Heck JE, Cockburn M, Su J, Jerrett M, Ritz B.

Am J Epidemiol. 2013 Oct 15;178(8):1233-9. doi: 10.1093/aje/kwt129. Epub 2013 Aug 28.


Dynamics of physical interaction between HIV-1 Nef and ASK1: identifying the interacting motif(s).

Kumar B, Tripathi C, Kanchan RK, Tripathi JK, Ghosh JK, Ramachandran R, Bhadauria S, Tripathi RK.

PLoS One. 2013 Jun 14;8(6):e67586. doi: 10.1371/journal.pone.0067586. Print 2013.


Acute pancreatitis associated with amoebic liver abscess.

Ghosh JK, Dixit VK, Lamtha SC, Goyal SK, Kaushik P.

Case Rep Gastrointest Med. 2013;2013:717393. doi: 10.1155/2013/717393. Epub 2013 Apr 2.


Introduction of a lysine residue promotes aggregation of temporin L in lipopolysaccharides and augmentation of its antiendotoxin property.

Srivastava S, Ghosh JK.

Antimicrob Agents Chemother. 2013 Jun;57(6):2457-66. doi: 10.1128/AAC.00169-13. Epub 2013 Mar 11.


Effects of residential indoor air quality and household ventilation on preterm birth and term low birth weight in Los Angeles County, California.

Ghosh JK, Wilhelm M, Ritz B.

Am J Public Health. 2013 Apr;103(4):686-94. doi: 10.2105/AJPH.2012.300987. Epub 2013 Feb 14.


Characterization of antimicrobial, cytotoxic, and antiendotoxin properties of short peptides with different hydrophobic amino acids at "a" and "d" positions of a heptad repeat sequence.

Azmi S, Srivastava S, Mishra NN, Tripathi JK, Shukla PK, Ghosh JK.

J Med Chem. 2013 Feb 14;56(3):924-39. doi: 10.1021/jm301407k. Epub 2013 Jan 30.


Assessing the influence of traffic-related air pollution on risk of term low birth weight on the basis of land-use-based regression models and measures of air toxics.

Ghosh JK, Wilhelm M, Su J, Goldberg D, Cockburn M, Jerrett M, Ritz B.

Am J Epidemiol. 2012 Jun 15;175(12):1262-74. doi: 10.1093/aje/kwr469. Epub 2012 May 13.


Consequences of alteration in leucine zipper sequence of melittin in its neutralization of lipopolysaccharide-induced proinflammatory response in macrophage cells and interaction with lipopolysaccharide.

Srivastava RM, Srivastava S, Singh M, Bajpai VK, Ghosh JK.

J Biol Chem. 2012 Jan 13;287(3):1980-95. doi: 10.1074/jbc.M111.302893. Epub 2011 Nov 29.


Traffic-related air toxics and preterm birth: a population-based case-control study in Los Angeles County, California.

Wilhelm M, Ghosh JK, Su J, Cockburn M, Jerrett M, Ritz B.

Environ Health. 2011 Oct 7;10:89. doi: 10.1186/1476-069X-10-89.


Traffic-related air toxics and term low birth weight in Los Angeles County, California.

Wilhelm M, Ghosh JK, Su J, Cockburn M, Jerrett M, Ritz B.

Environ Health Perspect. 2012 Jan;120(1):132-8. doi: 10.1289/ehp.1103408. Epub 2011 Aug 11.


A synthetic S6 segment derived from KvAP channel self-assembles, permeabilizes lipid vesicles, and exhibits ion channel activity in bilayer lipid membrane.

Verma R, Malik C, Azmi S, Srivastava S, Ghosh S, Ghosh JK.

J Biol Chem. 2011 Jul 15;286(28):24828-41. doi: 10.1074/jbc.M110.209676. Epub 2011 May 18.


Towards the synthesis of sugar amino acid containing antimicrobial noncytotoxic CAP conjugates with gold nanoparticles and a mechanistic study of cell disruption.

Pal S, Mitra K, Azmi S, Ghosh JK, Chakraborty TK.

Org Biomol Chem. 2011 Jul 7;9(13):4806-10. doi: 10.1039/c1ob05338h. Epub 2011 May 17.


Inducing toxicity by introducing a leucine-zipper-like motif in frog antimicrobial peptide, magainin 2.

Pandey BK, Srivastava S, Singh M, Ghosh JK.

Biochem J. 2011 Jun 15;436(3):609-20. doi: 10.1042/BJ20110056.


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