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Items: 1 to 50 of 91

1.

Temporal Dynamics of Reactive Oxygen and Nitrogen Species and NF-κB Activation During Acute and Chronic T Cell-Driven Inflammation.

Schwenck J, Mehling R, Thaiss WM, Kramer D, Menendez IG, Öz HH, Hartl D, Schulze-Osthoff K, Hailfinger S, Ghoreschi K, Quintanilla-Martinez L, Carlsen H, Röcken M, Pichler BJ, Kneilling M.

Mol Imaging Biol. 2019 Sep 3. doi: 10.1007/s11307-019-01412-8. [Epub ahead of print]

PMID:
31482411
2.

Platelets Aggregate With Neutrophils and Promote Skin Pathology in Psoriasis.

Herster F, Bittner Z, Codrea MC, Archer NK, Heister M, Löffler MW, Heumos S, Wegner J, Businger R, Schindler M, Stegner D, Schäkel K, Grabbe S, Ghoreschi K, Miller LS, Weber ANR.

Front Immunol. 2019 Aug 16;10:1867. doi: 10.3389/fimmu.2019.01867. eCollection 2019.

3.

Cysteine-type cathepsins promote the effector phase of acute cutaneous delayed-type hypersensitivity reactions.

Schwenck J, Maurer A, Fehrenbacher B, Mehling R, Knopf P, Mucha N, Haupt D, Fuchs K, Griessinger CM, Bukala D, Holstein J, Schaller M, Menendez IG, Ghoreschi K, Quintanilla-Martinez L, Gütschow M, Laufer S, Reinheckel T, Röcken M, Kalbacher H, Pichler BJ, Kneilling M.

Theranostics. 2019 May 31;9(13):3903-3917. doi: 10.7150/thno.31037. eCollection 2019.

4.

Imaging fibrosis in inflammatory diseases: targeting the exposed extracellular matrix.

Beziere N, Fuchs K, Maurer A, Reischl G, Brück J, Ghoreschi K, Fehrenbacher B, Berrio DC, Schenke-Layland K, Kohlhofer U, Quintanilla-Martinez L, Gawaz M, Kneilling M, Pichler B.

Theranostics. 2019 Apr 13;9(10):2868-2881. doi: 10.7150/thno.28892. eCollection 2019.

5.

T cell pathology in skin inflammation.

Sabat R, Wolk K, Loyal L, Döcke WD, Ghoreschi K.

Semin Immunopathol. 2019 May;41(3):359-377. doi: 10.1007/s00281-019-00742-7. Epub 2019 Apr 26. Review.

6.
7.

Long-term follow-up of early-onset Sneddon syndrome: A case report.

Forchhammer S, Metzler G, Ghoreschi K.

JAAD Case Rep. 2018 Oct 3;4(9):880-882. doi: 10.1016/j.jdcr.2018.08.008. eCollection 2018 Oct. No abstract available.

8.

Dimethyl fumarate-induced IL-17low IFN-γlow IL-4+ Th cells protect mice from severe encephalomyelitis.

Brück J, Glocova I, Geisel J, Kellerer C, Röcken M, Ghoreschi K.

Eur J Immunol. 2018 Sep;48(9):1588-1591. doi: 10.1002/eji.201747435. Epub 2018 Aug 22.

9.

Serpiginous Lesions in an Infant.

Maier J, Kofler L, Beck V, Schweinzer K, Ghoreschi K.

J Cutan Med Surg. 2018 May/Jun;22(3):327. doi: 10.1177/1203475417748887. No abstract available.

PMID:
29865948
10.

Development, Optimization, and Structure-Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4- d]pyrrolo[2,3- b]pyridine Scaffold.

Forster M, Chaikuad A, Dimitrov T, Döring E, Holstein J, Berger BT, Gehringer M, Ghoreschi K, Müller S, Knapp S, Laufer SA.

J Med Chem. 2018 Jun 28;61(12):5350-5366. doi: 10.1021/acs.jmedchem.8b00571. Epub 2018 Jun 13.

PMID:
29852068
11.

Ungewöhnliche Ulzerationen bei einem Patienten mit Diabetes mellitus.

Maier J, Kofler L, Beck V, Schweinzer K, Metzler G, Ghoreschi K.

J Dtsch Dermatol Ges. 2018 May;16(5):623-626. doi: 10.1111/ddg.13501_g. No abstract available.

PMID:
29750458
12.

Uncommon ulcers in a patient with diabetes.

Maier J, Kofler L, Beck V, Schweinzer K, Metzler G, Ghoreschi K.

J Dtsch Dermatol Ges. 2018 May;16(5):624-626. doi: 10.1111/ddg.13501. Epub 2018 Mar 30. No abstract available.

PMID:
29603621
13.

A review of the mechanisms of action of dimethylfumarate in the treatment of psoriasis.

Brück J, Dringen R, Amasuno A, Pau-Charles I, Ghoreschi K.

Exp Dermatol. 2018 Jun;27(6):611-624. doi: 10.1111/exd.13548. Epub 2018 Apr 25. Review.

PMID:
29603404
14.

Diagnostic value of autoantibody titres in patients with bullous pemphigoid.

Eckardt J, Eberle FC, Ghoreschi K.

Eur J Dermatol. 2018 Feb 1;28(1):3-12. doi: 10.1684/ejd.2017.3166.

PMID:
29336324
15.

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

Cossarizza A, Chang HD, Radbruch A, Akdis M, Andrä I, Annunziato F, Bacher P, Barnaba V, Battistini L, Bauer WM, Baumgart S, Becher B, Beisker W, Berek C, Blanco A, Borsellino G, Boulais PE, Brinkman RR, Büscher M, Busch DH, Bushnell TP, Cao X, Cavani A, Chattopadhyay PK, Cheng Q, Chow S, Clerici M, Cooke A, Cosma A, Cosmi L, Cumano A, Dang VD, Davies D, De Biasi S, Del Zotto G, Della Bella S, Dellabona P, Deniz G, Dessing M, Diefenbach A, Di Santo J, Dieli F, Dolf A, Donnenberg VS, Dörner T, Ehrhardt GRA, Endl E, Engel P, Engelhardt B, Esser C, Everts B, Dreher A, Falk CS, Fehniger TA, Filby A, Fillatreau S, Follo M, Förster I, Foster J, Foulds GA, Frenette PS, Galbraith D, Garbi N, García-Godoy MD, Geginat J, Ghoreschi K, Gibellini L, Goettlinger C, Goodyear CS, Gori A, Grogan J, Gross M, Grützkau A, Grummitt D, Hahn J, Hammer Q, Hauser AE, Haviland DL, Hedley D, Herrera G, Herrmann M, Hiepe F, Holland T, Hombrink P, Houston JP, Hoyer BF, Huang B, Hunter CA, Iannone A, Jäck HM, Jávega B, Jonjic S, Juelke K, Jung S, Kaiser T, Kalina T, Keller B, Khan S, Kienhöfer D, Kroneis T, Kunkel D, Kurts C, Kvistborg P, Lannigan J, Lantz O, Larbi A, LeibundGut-Landmann S, Leipold MD, Levings MK, Litwin V, Liu Y, Lohoff M, Lombardi G, Lopez L, Lovett-Racke A, Lubberts E, Ludewig B, Lugli E, Maecker HT, Martrus G, Matarese G, Maueröder C, McGrath M, McInnes I, Mei HE, Melchers F, Melzer S, Mielenz D, Mills K, Mirrer D, Mjösberg J, Moore J, Moran B, Moretta A, Moretta L, Mosmann TR, Müller S, Müller W, Münz C, Multhoff G, Munoz LE, Murphy KM, Nakayama T, Nasi M, Neudörfl C, Nolan J, Nourshargh S, O'Connor JE, Ouyang W, Oxenius A, Palankar R, Panse I, Peterson P, Peth C, Petriz J, Philips D, Pickl W, Piconese S, Pinti M, Pockley AG, Podolska MJ, Pucillo C, Quataert SA, Radstake TRDJ, Rajwa B, Rebhahn JA, Recktenwald D, Remmerswaal EBM, Rezvani K, Rico LG, Robinson JP, Romagnani C, Rubartelli A, Ruckert B, Ruland J, Sakaguchi S, Sala-de-Oyanguren F, Samstag Y, Sanderson S, Sawitzki B, Scheffold A, Schiemann M, Schildberg F, Schimisky E, Schmid SA, Schmitt S, Schober K, Schüler T, Schulz AR, Schumacher T, Scotta C, Shankey TV, Shemer A, Simon AK, Spidlen J, Stall AM, Stark R, Stehle C, Stein M, Steinmetz T, Stockinger H, Takahama Y, Tarnok A, Tian Z, Toldi G, Tornack J, Traggiai E, Trotter J, Ulrich H, van der Braber M, van Lier RAW, Veldhoen M, Vento-Asturias S, Vieira P, Voehringer D, Volk HD, von Volkmann K, Waisman A, Walker R, Ward MD, Warnatz K, Warth S, Watson JV, Watzl C, Wegener L, Wiedemann A, Wienands J, Willimsky G, Wing J, Wurst P, Yu L, Yue A, Zhang Q, Zhao Y, Ziegler S, Zimmermann J.

Eur J Immunol. 2017 Oct;47(10):1584-1797. doi: 10.1002/eji.201646632. No abstract available.

16.

Anthralin modulates the expression pattern of cytokeratins and antimicrobial peptides by psoriatic keratinocytes.

Holstein J, Fehrenbacher B, Brück J, Müller-Hermelink E, Schäfer I, Carevic M, Schittek B, Schaller M, Ghoreschi K, Eberle FC.

J Dermatol Sci. 2017 Sep;87(3):236-245. doi: 10.1016/j.jdermsci.2017.06.007. Epub 2017 Jun 15.

PMID:
28673488
17.

Induction of skin-pathogenic Th22 cells by epicutaneous allergen exposure.

Glocova I, Brück J, Geisel J, Müller-Hermelink E, Widmaier K, Yazdi AS, Röcken M, Ghoreschi K.

J Dermatol Sci. 2017 Sep;87(3):268-277. doi: 10.1016/j.jdermsci.2017.06.006. Epub 2017 Jun 9.

PMID:
28655472
18.

Differential induction of ATF3 and HO-1 in myeloid cells and keratinocytes via Dimethylfumarate or Cyclosporine A.

Müller S, Smatlik N, Burian M, Ghoreschi K, Röcken M, Yazdi AS.

J Dermatol Sci. 2017 Sep;87(3):246-251. doi: 10.1016/j.jdermsci.2017.06.005. Epub 2017 Jun 12.

PMID:
28633807
19.

Targeting JAK/STAT signalling in inflammatory skin diseases with small molecule inhibitors.

Welsch K, Holstein J, Laurence A, Ghoreschi K.

Eur J Immunol. 2017 Jul;47(7):1096-1107. doi: 10.1002/eji.201646680. Epub 2017 Jun 21. Review.

20.

Nutritional control of IL-23/Th17-mediated autoimmune disease through HO-1/STAT3 activation.

Brück J, Holstein J, Glocova I, Seidel U, Geisel J, Kanno T, Kumagai J, Mato N, Sudowe S, Widmaier K, Sinnberg T, Yazdi AS, Eberle FC, Hirahara K, Nakayama T, Röcken M, Ghoreschi K.

Sci Rep. 2017 Mar 14;7:44482. doi: 10.1038/srep44482.

21.

Anti-melanoma differentiation-associated protein 5 autoantibodies as a marker for dermatomyositis-associated interstitial lung disease.

Jordan M, Ghoreschi K.

Br J Dermatol. 2017 Feb;176(2):294-295. doi: 10.1111/bjd.15257. No abstract available.

PMID:
28244092
22.

The role of IL-4 in psoriasis.

Hahn M, Ghoreschi K.

Expert Rev Clin Immunol. 2017 Mar;13(3):171-173. doi: 10.1080/1744666X.2017.1279054. Epub 2017 Jan 16. No abstract available.

PMID:
28064550
23.

An intensified dosing schedule of subcutaneous methotrexate in patients with moderate to severe plaque-type psoriasis (METOP): a 52 week, multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.

Warren RB, Mrowietz U, von Kiedrowski R, Niesmann J, Wilsmann-Theis D, Ghoreschi K, Zschocke I, Falk TM, Blödorn-Schlicht N, Reich K.

Lancet. 2017 Feb 4;389(10068):528-537. doi: 10.1016/S0140-6736(16)32127-4. Epub 2016 Dec 22.

PMID:
28012564
24.

Selective JAK3 Inhibitors with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket.

Forster M, Chaikuad A, Bauer SM, Holstein J, Robers MB, Corona CR, Gehringer M, Pfaffenrot E, Ghoreschi K, Knapp S, Laufer SA.

Cell Chem Biol. 2016 Nov 17;23(11):1335-1340. doi: 10.1016/j.chembiol.2016.10.008. Epub 2016 Nov 10.

25.

ADF Winter School-An exciting concept of the Arbeitsgemeinschaft Dermatologische Forschung to connect young scientists and clinician scientists in Dermatology at the top of Germany.

Yazdi AS, Barlin M, Böhm K, Gendrisch F, Ghorbanalipoor S, Häberle S, Hamel A, Hüning S, Hüttner C, Iwanova I, Kanaki T, Kimeswenger S, Lohmann N, Munir S, Muzumdar S, Pereira MP, Peking P, Plesser K, Rendon A, Rentschler M, Schlumprecht C, Smorodchenko A, Stock M, Tillmanns J, Uslu U, Ghoreschi K, Glatz M, Grabbe S, Kunz M, Ludwig R, Scharffetter-Kochanek K, Loser K.

Exp Dermatol. 2017 Mar;26(3):292-294. doi: 10.1111/exd.13241. Epub 2016 Nov 3. No abstract available.

PMID:
27808431
26.

Reporting the response to anti-tumour necrosis factor treatment.

Volc S, Ghoreschi K.

Br J Dermatol. 2016 Nov;175(5):867-868. doi: 10.1111/bjd.14988. No abstract available.

PMID:
27790684
27.

The Interleukin-1 Family.

Yazdi AS, Ghoreschi K.

Adv Exp Med Biol. 2016;941:21-29. Review.

PMID:
27734407
28.

S1-Leitlinie zur UV-Phototherapie und Photochemotherapie.

Herzinger T, Berneburg M, Ghoreschi K, Gollnick H, Hölzle E, Hönigsmann H, Lehmann P, Peters T, Röcken M, Scharffetter-Kochanek K, Schwarz T, Simon J, Tanew A, Weichenthal M.

J Dtsch Dermatol Ges. 2016 Aug;14(8):e1-e25. doi: 10.1111/ddg.12912_g.

PMID:
27509439
29.

S1-Guidelines on UV phototherapy and photochemotherapy.

Herzinger T, Berneburg M, Ghoreschi K, Gollnick H, Hölzle E, Hönigsmann H, Lehmann P, Peters T, Röcken M, Scharffetter-Kochanek K, Schwarz T, Simon J, Tanew A, Weichenthal M.

J Dtsch Dermatol Ges. 2016 Aug;14(8):853-76. doi: 10.1111/ddg.12912. Review.

PMID:
27509435
30.

[Pathogenesis of psoriasis].

Schäkel K, Schön MP, Ghoreschi K.

Hautarzt. 2016 Jun;67(6):422-31. doi: 10.1007/s00105-016-3800-8. Review. German.

PMID:
27246016
31.

Pathophysiological basis of systemic treatments in psoriasis.

Volc S, Ghoreschi K.

J Dtsch Dermatol Ges. 2016 Jun;14(6):557-72. doi: 10.1111/ddg.13050. Review.

PMID:
27240060
32.

Pathophysiologische Grundlagen der Systemtherapien bei Psoriasis.

Volc S, Ghoreschi K.

J Dtsch Dermatol Ges. 2016 Jun;14(6):557-73. doi: 10.1111/ddg.13050_g. No abstract available.

PMID:
27240059
33.

Recent advances in understanding psoriasis.

Eberle FC, Brück J, Holstein J, Hirahara K, Ghoreschi K.

F1000Res. 2016 Apr 28;5. pii: F1000 Faculty Rev-770. doi: 10.12688/f1000research.7927.1. eCollection 2016. Review.

34.

Increased Frequency of T Follicular Helper Cells and Elevated Interleukin-27 Plasma Levels in Patients with Pemphigus.

Hennerici T, Pollmann R, Schmidt T, Seipelt M, Tackenberg B, Möbs C, Ghoreschi K, Hertl M, Eming R.

PLoS One. 2016 Feb 12;11(2):e0148919. doi: 10.1371/journal.pone.0148919. eCollection 2016.

35.

The single-chain anti-TNF-α antibody DLX105 induces clinical and biomarker responses upon local administration in patients with chronic plaque-type psoriasis.

Tsianakas A, Brunner PM, Ghoreschi K, Berger C, Loser K, Röcken M, Stingl G, Luger T, Jung T.

Exp Dermatol. 2016 Jun;25(6):428-33. doi: 10.1111/exd.12927. Epub 2016 Feb 13.

PMID:
26738450
36.

Cutaneous immunology: basics and new concepts.

Yazdi AS, Röcken M, Ghoreschi K.

Semin Immunopathol. 2016 Jan;38(1):3-10. doi: 10.1007/s00281-015-0545-x. Epub 2015 Nov 12. Review.

PMID:
26563284
37.

Update on the treatment of psoriasis and psoriatic arthritis - role of apremilast.

Forchhammer S, Ghoreschi K.

Psoriasis (Auckl). 2015 Sep 7;5:117-124. doi: 10.2147/PTT.S69476. eCollection 2015. Review.

38.

Cholesterol Modification of p40-Specific Small Interfering RNA Enables Therapeutic Targeting of Dendritic Cells.

Brück J, Pascolo S, Fuchs K, Kellerer C, Glocova I, Geisel J, Dengler K, Yazdi AS, Röcken M, Ghoreschi K.

J Immunol. 2015 Sep 1;195(5):2216-23. doi: 10.4049/jimmunol.1402989. Epub 2015 Jul 31.

39.

Restless legs syndrome in psoriasis: an unexpected comorbidity.

Schell C, Schleich R, Walker F, Yazdi AS, Lerche H, Röcken M, Axmann D, Ghoreschi K, Eberle FC.

Eur J Dermatol. 2015 May-Jun;25(3):255-60. doi: 10.1684/ejd.2015.2525.

PMID:
25786537
40.

IL-4 abrogates T(H)17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells.

Guenova E, Skabytska Y, Hoetzenecker W, Weindl G, Sauer K, Tham M, Kim KW, Park JH, Seo JH, Ignatova D, Cozzio A, Levesque MP, Volz T, Köberle M, Kaesler S, Thomas P, Mailhammer R, Ghoreschi K, Schäkel K, Amarov B, Eichner M, Schaller M, Clark RA, Röcken M, Biedermann T.

Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):2163-8. doi: 10.1073/pnas.1416922112. Epub 2015 Feb 2.

41.

Tofacitinib suppresses antibody responses to protein therapeutics in murine hosts.

Onda M, Ghoreschi K, Steward-Tharp S, Thomas C, O'Shea JJ, Pastan IH, FitzGerald DJ.

J Immunol. 2014 Jul 1;193(1):48-55. doi: 10.4049/jimmunol.1400063. Epub 2014 Jun 2.

42.

Fumaderm® in daily practice for psoriasis: dosing, efficacy and quality of life.

Walker F, Adamczyk A, Kellerer C, Belge K, Brück J, Berner T, Merten K, Núnez Gómez N, Neureither M, Röcken M, Ghoreschi K; Study group.

Br J Dermatol. 2014 Nov;171(5):1197-205. doi: 10.1111/bjd.13098. Epub 2014 Oct 1.

PMID:
24813676
43.

Sulforaphane protects from T cell-mediated autoimmune disease by inhibition of IL-23 and IL-12 in dendritic cells.

Geisel J, Brück J, Glocova I, Dengler K, Sinnberg T, Rothfuss O, Walter M, Schulze-Osthoff K, Röcken M, Ghoreschi K.

J Immunol. 2014 Apr 15;192(8):3530-9. doi: 10.4049/jimmunol.1300556. Epub 2014 Mar 17.

44.

Advances in treating psoriasis.

Belge K, Brück J, Ghoreschi K.

F1000Prime Rep. 2014 Jan 2;6:4. doi: 10.12703/P6-4. eCollection 2014. Review.

45.

Reversal of CD8 T-cell-mediated mucocutaneous graft-versus-host-like disease by the JAK inhibitor tofacitinib.

Okiyama N, Furumoto Y, Villarroel VA, Linton JT, Tsai WL, Gutermuth J, Ghoreschi K, Gadina M, O'Shea JJ, Katz SI.

J Invest Dermatol. 2014 Apr;134(4):992-1000. doi: 10.1038/jid.2013.476. Epub 2013 Nov 8.

46.

Jakpot! New small molecules in autoimmune and inflammatory diseases.

Ghoreschi K, Gadina M.

Exp Dermatol. 2014 Jan;23(1):7-11. doi: 10.1111/exd.12265. Review.

47.

Tissue inhibitor of metalloproteinase 1 is preferentially expressed in Th1 and Th17 T-helper cell subsets and is a direct STAT target gene.

Adamson A, Ghoreschi K, Rittler M, Chen Q, Sun HW, Vahedi G, Kanno Y, Stetler-Stevenson WG, O'Shea JJ, Laurence A.

PLoS One. 2013;8(3):e59367. doi: 10.1371/journal.pone.0059367. Epub 2013 Mar 26.

48.

[New insights into fumaric acid esters (Fumaderm ®):results of the 2nd Expert Workshops].

Mrowietz U, Altmeyer P, Augustin M, Boehncke WH, Bonnekoh B, Frambach Y, Gambichler T, Ghoreschi K, Hertl M, Hund AC, Jacobi A, Kuhn A, Ludwig RJ, Luger T, Martin SF, Merk H, Norgauer J, Reich K, Rostami-Yazdi M, Sabat R, Schäkel K, Scharffetter-Kochanek K, Schön MP, Scola N, Sticherling M, Thaci D, Wilsmann-Theis D, Viehweg A, Wozel G, Zouboulis CC, Neureither M.

J Dtsch Dermatol Ges. 2012 Dec;10 Suppl 8:1-15. doi: 10.1111/j.1610-0379.2012.08047.x. German. No abstract available.

PMID:
23198820
49.

Manifestation of rheumatoid arthritis during subcutaneous allergen-specific immunotherapy with bee venom.

Ghoreschi K, Fischer J, Biedermann T.

J Allergy Clin Immunol. 2012 Dec;130(6):1438-9; author reply 1439-40. doi: 10.1016/j.jaci.2012.08.052. Epub 2012 Oct 23. No abstract available.

PMID:
23098811
50.

Interleukin-27 priming of T cells controls IL-17 production in trans via induction of the ligand PD-L1.

Hirahara K, Ghoreschi K, Yang XP, Takahashi H, Laurence A, Vahedi G, Sciumè G, Hall AO, Dupont CD, Francisco LM, Chen Q, Tanaka M, Kanno Y, Sun HW, Sharpe AH, Hunter CA, O'Shea JJ.

Immunity. 2012 Jun 29;36(6):1017-30. doi: 10.1016/j.immuni.2012.03.024. Epub 2012 Jun 21.

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