Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 59

1.

Secreted PLA2 group X orchestrates innate and adaptive immune responses to inhaled allergen.

Nolin JD, Lai Y, Ogden HL, Manicone AM, Murphy RC, An D, Frevert CW, Ghomashchi F, Naika GS, Gelb MH, Gauvreau GM, Piliponsky AM, Altemeier WA, Hallstrand TS.

JCI Insight. 2017 Nov 2;2(21). pii: 94929. doi: 10.1172/jci.insight.94929.

2.

Lymphocyte Galactocerebrosidase Activity by LC-MS/MS for Post-Newborn Screening Evaluation of Krabbe Disease.

Liao HC, Spacil Z, Ghomashchi F, Escolar ML, Kurtzberg J, Orsini JJ, Turecek F, Scott CR, Gelb MH.

Clin Chem. 2017 Aug;63(8):1363-1369. doi: 10.1373/clinchem.2016.264952. Epub 2017 Jun 7.

3.

Liquid Chromatography-Tandem Mass Spectrometry Assay of Leukocyte Acid α-Glucosidase for Post-Newborn Screening Evaluation of Pompe Disease.

Lin N, Huang J, Violante S, Orsini JJ, Caggana M, Hughes EE, Stevens C, DiAntonio L, Chieh Liao H, Hong X, Ghomashchi F, Babu Kumar A, Zhou H, Kornreich R, Wasserstein M, Gelb MH, Yu C.

Clin Chem. 2017 Apr;63(4):842-851. doi: 10.1373/clinchem.2016.259036. Epub 2017 Feb 14.

4.

Preparation of the Full Set of Recombinant Mouse- and Human-Secreted Phospholipases A2.

Ghomashchi F, Brglez V, Payré C, Jeammet L, Bezzine S, Gelb MH, Lambeau G.

Methods Enzymol. 2017;583:35-69. doi: 10.1016/bs.mie.2016.10.034. Epub 2016 Dec 23.

PMID:
28063498
5.

Tandem Mass Spectrometry Has a Larger Analytical Range than Fluorescence Assays of Lysosomal Enzymes: Application to Newborn Screening and Diagnosis of Mucopolysaccharidoses Types II, IVA, and VI.

Kumar AB, Masi S, Ghomashchi F, Chennamaneni NK, Ito M, Scott CR, Turecek F, Gelb MH, Spacil Z.

Clin Chem. 2015 Nov;61(11):1363-71. doi: 10.1373/clinchem.2015.242560. Epub 2015 Sep 14.

6.

Fluorimetric assays for N-acetylgalactosamine-6-sulfatase and arylsulfatase B based on the natural substrates for confirmation of mucopolysaccharidoses types IVA and VI.

Kumar AB, Spacil Z, Ghomashchi F, Masi S, Sumida T, Ito M, Turecek F, Scott CR, Gelb MH.

Clin Chim Acta. 2015 Dec 7;451(Pt B):125-8. doi: 10.1016/j.cca.2015.08.010. Epub 2015 Aug 15.

7.

Matrix metalloproteinase-2 negatively regulates cardiac secreted phospholipase A2 to modulate inflammation and fever.

Berry E, Hernandez-Anzaldo S, Ghomashchi F, Lehner R, Murakami M, Gelb MH, Kassiri Z, Wang X, Fernandez-Patron C.

J Am Heart Assoc. 2015 Mar 27;4(4). pii: e001868. doi: 10.1161/JAHA.115.001868.

8.

Reliable Assay of Acid Sphingomyelinase Deficiency with the Mutation Q292K by Tandem Mass Spectrometry.

Ghomashchi F, Barcenas M, Turecek F, Scott CR, Gelb MH.

Clin Chem. 2015 May;61(5):771-2. doi: 10.1373/clinchem.2014.236448. Epub 2015 Mar 13. No abstract available.

9.

New substrates and enzyme assays for the detection of mucopolysaccharidosis III (Sanfilippo Syndrome) types A, B, C, and D by tandem mass spectrometry.

Wolfe BJ, Ghomashchi F, Kim T, Abam CA, Sadilek M, Jack R, Thompson JN, Scott CR, Gelb MH, Turecek F.

Bioconjug Chem. 2012 Mar 21;23(3):557-64. doi: 10.1021/bc200609x. Epub 2012 Mar 9.

10.

Functional characterization of mutations in inherited human cPLA₂ deficiency.

Reed KA, Tucker DE, Aloulou A, Adler D, Ghomashchi F, Gelb MH, Leslie CC, Oates JA, Boutaud O.

Biochemistry. 2011 Mar 15;50(10):1731-8. doi: 10.1021/bi101877n. Epub 2011 Feb 9.

11.

Interfacial kinetic and binding properties of mammalian group IVB phospholipase A2 (cPLA2beta) and comparison with the other cPLA2 isoforms.

Ghomashchi F, Naika GS, Bollinger JG, Aloulou A, Lehr M, Leslie CC, Gelb MH.

J Biol Chem. 2010 Nov 12;285(46):36100-11. doi: 10.1074/jbc.M110.165647. Epub 2010 Aug 11.

12.

A novel anti-inflammatory role for secretory phospholipase A2 in immune complex-mediated arthritis.

Boilard E, Lai Y, Larabee K, Balestrieri B, Ghomashchi F, Fujioka D, Gobezie R, Coblyn JS, Weinblatt ME, Massarotti EM, Thornhill TS, Divangahi M, Remold H, Lambeau G, Gelb MH, Arm JP, Lee DM.

EMBO Mol Med. 2010 May;2(5):172-87. doi: 10.1002/emmm.201000072.

13.

Role of phosphorylation and basic residues in the catalytic domain of cytosolic phospholipase A2alpha in regulating interfacial kinetics and binding and cellular function.

Tucker DE, Ghosh M, Ghomashchi F, Loper R, Suram S, John BS, Girotti M, Bollinger JG, Gelb MH, Leslie CC.

J Biol Chem. 2009 Apr 3;284(14):9596-611. doi: 10.1074/jbc.M807299200. Epub 2009 Jan 28.

14.
15.

Function, activity, and membrane targeting of cytosolic phospholipase A(2)zeta in mouse lung fibroblasts.

Ghosh M, Loper R, Ghomashchi F, Tucker DE, Bonventre JV, Gelb MH, Leslie CC.

J Biol Chem. 2007 Apr 20;282(16):11676-86. Epub 2007 Feb 11.

16.

Recombinant production and properties of binding of the full set of mouse secreted phospholipases A2 to the mouse M-type receptor.

Rouault M, Le Calvez C, Boilard E, Surrel F, Singer A, Ghomashchi F, Bezzine S, Scarzello S, Bollinger J, Gelb MH, Lambeau G.

Biochemistry. 2007 Feb 13;46(6):1647-62.

PMID:
17279628
17.

Group IVC cytosolic phospholipase A2gamma is farnesylated and palmitoylated in mammalian cells.

Tucker DE, Stewart A, Nallan L, Bendale P, Ghomashchi F, Gelb MH, Leslie CC.

J Lipid Res. 2005 Oct;46(10):2122-33. Epub 2005 Aug 1.

18.

Interfacial binding of bee venom secreted phospholipase A2 to membranes occurs predominantly by a nonelectrostatic mechanism.

Bollinger JG, Diraviyam K, Ghomashchi F, Murray D, Gelb MH.

Biochemistry. 2004 Oct 26;43(42):13293-304.

PMID:
15491136
19.

Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase activity.

Rubin BB, Downey GP, Koh A, Degousee N, Ghomashchi F, Nallan L, Stefanski E, Harkin DW, Sun C, Smart BP, Lindsay TF, Cherepanov V, Vachon E, Kelvin D, Sadilek M, Brown GE, Yaffe MB, Plumb J, Grinstein S, Glogauer M, Gelb MH.

J Biol Chem. 2005 Mar 4;280(9):7519-29. Epub 2004 Oct 8.

20.
21.

Interfacial enzymology of parvovirus phospholipases A2.

Canaan S, Zádori Z, Ghomashchi F, Bollinger J, Sadilek M, Moreau ME, Tijssen P, Gelb MH.

J Biol Chem. 2004 Apr 9;279(15):14502-8. Epub 2004 Jan 15.

22.

Differentiation-dependent regulation of secreted phospholipases A2 in murine epidermis.

Gurrieri S, Fürstenberger G, Schadow A, Haas U, Singer AG, Ghomashchi F, Pfeilschifter J, Lambeau G, Gelb MH, Kaszkin M.

J Invest Dermatol. 2003 Jul;121(1):156-64.

23.

Interfacial kinetic and binding properties of the complete set of human and mouse groups I, II, V, X, and XII secreted phospholipases A2.

Singer AG, Ghomashchi F, Le Calvez C, Bollinger J, Bezzine S, Rouault M, Sadilek M, Nguyen E, Lazdunski M, Lambeau G, Gelb MH.

J Biol Chem. 2002 Dec 13;277(50):48535-49. Epub 2002 Sep 30.

24.

Crystal structure of human group X secreted phospholipase A2. Electrostatically neutral interfacial surface targets zwitterionic membranes.

Pan YH, Yu BZ, Singer AG, Ghomashchi F, Lambeau G, Gelb MH, Jain MK, Bahnson BJ.

J Biol Chem. 2002 Aug 9;277(32):29086-93. Epub 2002 May 25.

25.
26.

Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis.

Degousee N, Ghomashchi F, Stefanski E, Singer A, Smart BP, Borregaard N, Reithmeier R, Lindsay TF, Lichtenberger C, Reinisch W, Lambeau G, Arm J, Tischfield J, Gelb MH, Rubin BB.

J Biol Chem. 2002 Feb 15;277(7):5061-73. Epub 2001 Dec 6.

27.

A pyrrolidine-based specific inhibitor of cytosolic phospholipase A(2)alpha blocks arachidonic acid release in a variety of mammalian cells.

Ghomashchi F, Stewart A, Hefner Y, Ramanadham S, Turk J, Leslie CC, Gelb MH.

Biochim Biophys Acta. 2001 Aug 6;1513(2):160-6. Erratum in: Biochim Biophys Acta. 2011 Jun;1808(6):1779.

28.

Distinct arachidonate-releasing functions of mammalian secreted phospholipase A2s in human embryonic kidney 293 and rat mastocytoma RBL-2H3 cells through heparan sulfate shuttling and external plasma membrane mechanisms.

Murakami M, Koduri RS, Enomoto A, Shimbara S, Seki M, Yoshihara K, Singer A, Valentin E, Ghomashchi F, Lambeau G, Gelb MH, Kudo I.

J Biol Chem. 2001 Mar 30;276(13):10083-96. Epub 2000 Dec 5.

29.

Cloning and recombinant expression of human group IIF-secreted phospholipase A(2).

Valentin E, Singer AG, Ghomashchi F, Lazdunski M, Gelb MH, Lambeau G.

Biochem Biophys Res Commun. 2000 Dec 9;279(1):223-8.

PMID:
11112443
30.

Binding of the delta subunit to rod phosphodiesterase catalytic subunits requires methylated, prenylated C-termini of the catalytic subunits.

Cook TA, Ghomashchi F, Gelb MH, Florio SK, Beavo JA.

Biochemistry. 2000 Nov 7;39(44):13516-23.

PMID:
11063588
31.

The delta subunit of type 6 phosphodiesterase reduces light-induced cGMP hydrolysis in rod outer segments.

Cook TA, Ghomashchi F, Gelb MH, Florio SK, Beavo JA.

J Biol Chem. 2001 Feb 16;276(7):5248-55. Epub 2000 Oct 26.

32.

Cloning and recombinant expression of a structurally novel human secreted phospholipase A2.

Gelb MH, Valentin E, Ghomashchi F, Lazdunski M, Lambeau G.

J Biol Chem. 2000 Dec 22;275(51):39823-6.

33.

Serine 727 phosphorylation and activation of cytosolic phospholipase A2 by MNK1-related protein kinases.

Hefner Y, Borsch-Haubold AG, Murakami M, Wilde JI, Pasquet S, Schieltz D, Ghomashchi F, Yates JR 3rd, Armstrong CG, Paterson A, Cohen P, Fukunaga R, Hunter T, Kudo I, Watson SP, Gelb MH.

J Biol Chem. 2000 Dec 1;275(48):37542-51.

34.

Basic residues of human group IIA phospholipase A2 are important for binding to factor Xa and prothrombinase inhibition comparison with other mammalian secreted phospholipases A2.

Mounier CM, Luchetta P, Lecut C, Koduri RS, Faure G, Lambeau G, Valentin E, Singer A, Ghomashchi F, Béguin S, Gelb MH, Bon C.

Eur J Biochem. 2000 Aug;267(16):4960-9.

35.

Structural analysis of protein prenyl groups and associated C-terminal modifications.

Whitten ME, Yokoyama K, Schieltz D, Ghomashchi F, Lam D, Yates JR 3rd, Palczewski K, Gelb MH.

Methods Enzymol. 2000;316:436-51. No abstract available.

36.

Novel human secreted phospholipase A(2) with homology to the group III bee venom enzyme.

Valentin E, Ghomashchi F, Gelb MH, Lazdunski M, Lambeau G.

J Biol Chem. 2000 Mar 17;275(11):7492-6.

37.

Exogenously added human group X secreted phospholipase A(2) but not the group IB, IIA, and V enzymes efficiently release arachidonic acid from adherent mammalian cells.

Bezzine S, Koduri RS, Valentin E, Murakami M, Kudo I, Ghomashchi F, Sadilek M, Lambeau G, Gelb MH.

J Biol Chem. 2000 Feb 4;275(5):3179-91.

38.

Stress stimuli increase calcium-induced arachidonic acid release through phosphorylation of cytosolic phospholipase A2.

Buschbeck M, Ghomashchi F, Gelb MH, Watson SP, Börsch-Haubold AG.

Biochem J. 1999 Dec 1;344 Pt 2:359-66.

39.

On the diversity of secreted phospholipases A(2). Cloning, tissue distribution, and functional expression of two novel mouse group II enzymes.

Valentin E, Ghomashchi F, Gelb MH, Lazdunski M, Lambeau G.

J Biol Chem. 1999 Oct 29;274(44):31195-202. Erratum in: J Biol Chem 2000 Jan 21;275(3):2246.

40.

Phosphorylation of cytosolic phospholipase A2 in platelets is mediated by multiple stress-activated protein kinase pathways.

Börsch-Haubold AG, Ghomashchi F, Pasquet S, Goedert M, Cohen P, Gelb MH, Watson SP.

Eur J Biochem. 1999 Oct 1;265(1):195-203.

41.

Trifluoromethyl ketones and methyl fluorophosphonates as inhibitors of group IV and VI phospholipases A(2): structure-function studies with vesicle, micelle, and membrane assays.

Ghomashchi F, Loo R, Balsinde J, Bartoli F, Apitz-Castro R, Clark JD, Dennis EA, Gelb MH.

Biochim Biophys Acta. 1999 Aug 20;1420(1-2):45-56.

42.

Binding of bee venom and human group IIa phospholipases A2 to membranes: a minor role for electrostatics.

Lin Y, Ghomashchi F, Nielsen R, Snitko Y, Yu BZ, Han SK, Cho W, Wilton DC, Jain MK, Robinson BH, Gelb MH.

Biochem Soc Trans. 1998 Aug;26(3):341-5. Review. No abstract available.

PMID:
9765875
43.

Interfacial recognition by bee venom phospholipase A2: insights into nonelectrostatic molecular determinants by charge reversal mutagenesis.

Ghomashchi F, Lin Y, Hixon MS, Yu BZ, Annand R, Jain MK, Gelb MH.

Biochemistry. 1998 May 12;37(19):6697-710.

PMID:
9578553
44.
45.

Localization of structural elements of bee venom phospholipase A2 involved in N-type receptor binding and neurotoxicity.

Nicolas JP, Lin Y, Lambeau G, Ghomashchi F, Lazdunski M, Gelb MH.

J Biol Chem. 1997 Mar 14;272(11):7173-81.

46.

Identification of phosphorylation sites of human 85-kDa cytosolic phospholipase A2 expressed in insect cells and present in human monocytes.

de Carvalho MG, McCormack AL, Olson E, Ghomashchi F, Gelb MH, Yates JR 3rd, Leslie CC.

J Biol Chem. 1996 Mar 22;271(12):6987-97.

47.

Continuous, vesicle-based fluorimetric assays of 14- and 85-kDa phospholipases A2.

Bayburt T, Yu BZ, Street I, Ghomashchi F, Laliberté F, Perrier H, Wang Z, Homan R, Jain MK, Gelb MH.

Anal Biochem. 1995 Nov 20;232(1):7-23.

PMID:
8600835
48.

Binding of prenylated and polybasic peptides to membranes: affinities and intervesicle exchange.

Ghomashchi F, Zhang X, Liu L, Gelb MH.

Biochemistry. 1995 Sep 19;34(37):11910-8.

PMID:
7547927
49.

The inhibition of protein prenyltransferases by oxygenated metabolites of limonene and perillyl alcohol.

Gelb MH, Tamanoi F, Yokoyama K, Ghomashchi F, Esson K, Gould MN.

Cancer Lett. 1995 May 8;91(2):169-75.

PMID:
7767906
50.

Conodipine-M, a novel phospholipase A2 isolated from the venom of the marine snail Conus magus.

McIntosh JM, Ghomashchi F, Gelb MH, Dooley DJ, Stoehr SJ, Giordani AB, Naisbitt SR, Olivera BM.

J Biol Chem. 1995 Feb 24;270(8):3518-26.

Supplemental Content

Loading ...
Support Center