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Items: 20


GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells.

Smith EL, Harrington K, Staehr M, Masakayan R, Jones J, Long TJ, Ng KY, Ghoddusi M, Purdon TJ, Wang X, Do T, Pham MT, Brown JM, De Larrea CF, Olson E, Peguero E, Wang P, Liu H, Xu Y, Garrett-Thomson SC, Almo SC, Wendel HG, Riviere I, Liu C, Sather B, Brentjens RJ.

Sci Transl Med. 2019 Mar 27;11(485). pii: eaau7746. doi: 10.1126/scitranslmed.aau7746.


Preclinical Antitumor Activity of a Novel Anti-c-KIT Antibody-Drug Conjugate against Mutant and Wild-type c-KIT-Positive Solid Tumors.

Abrams T, Connor A, Fanton C, Cohen SB, Huber T, Miller K, Hong EE, Niu X, Kline J, Ison-Dugenny M, Harris S, Walker D, Krauser K, Galimi F, Wang Z, Ghoddusi M, Mansfield K, Lee-Hoeflich ST, Holash J, Pryer N, Kluwe W, Ettenberg SA, Sellers WR, Lees E, Kwon P, Abraham JA, Schleyer SC.

Clin Cancer Res. 2018 Sep 1;24(17):4297-4308. doi: 10.1158/1078-0432.CCR-17-3795. Epub 2018 May 15.


A synthetic lethal screen reveals enhanced sensitivity to ATR inhibitor treatment in mantle cell lymphoma with ATM loss-of-function.

Menezes DL, Holt J, Tang Y, Feng J, Barsanti P, Pan Y, Ghoddusi M, Zhang W, Thomas G, Holash J, Lees E, Taricani L.

Mol Cancer Res. 2015 Jan;13(1):120-9. doi: 10.1158/1541-7786.MCR-14-0240. Epub 2014 Sep 17.


Vemurafenib cooperates with HPV to promote initiation of cutaneous tumors.

Holderfield M, Lorenzana E, Weisburd B, Lomovasky L, Boussemart L, Lacroix L, Tomasic G, Favre M, Vagner S, Robert C, Ghoddusi M, Daniel D, Pryer N, McCormick F, Stuart D.

Cancer Res. 2014 Apr 15;74(8):2238-45. doi: 10.1158/0008-5472.CAN-13-1065-T. Epub 2014 Feb 12.


Neutralization of prolactin receptor function by monoclonal antibody LFA102, a novel potential therapeutic for the treatment of breast cancer.

Damiano JS, Rendahl KG, Karim C, Embry MG, Ghoddusi M, Holash J, Fanidi A, Abrams TJ, Abraham JA.

Mol Cancer Ther. 2013 Mar;12(3):295-305. doi: 10.1158/1535-7163.MCT-12-0886. Epub 2012 Dec 27.


14-day repeat-dose oral toxicity evaluation of oxazyme in rats and dogs.

Cowley AB, Poage DW, Dean RR, Meschter CL, Ghoddusi M, Li QS, Sidhu H.

Int J Toxicol. 2010 Jan-Feb;29(1):20-31. doi: 10.1177/1091581809353611. Epub 2009 Dec 7.


Cutaneous pythiosis in a nontravelled California horse.

White SD, Ghoddusi M, Grooters AM, Jones K.

Vet Dermatol. 2008 Dec;19(6):391-4. doi: 10.1111/j.1365-3164.2008.00690.x. Epub 2008 Aug 5.


Mechanisms underlying intranuclear rod formation.

Domazetovska A, Ilkovski B, Cooper ST, Ghoddusi M, Hardeman EC, Minamide LS, Gunning PW, Bamburg JR, North KN.

Brain. 2007 Dec;130(Pt 12):3275-84. Epub 2007 Oct 10.


Ultrastructural changes and sarcoplasmic reticulum Ca2+ regulation in red vastus muscle following eccentric exercise in the rat.

Chen W, Ruell PA, Ghoddusi M, Kee A, Hardeman EC, Hoffman KM, Thompson MW.

Exp Physiol. 2007 Mar;92(2):437-47. Epub 2006 Nov 30.


Skeletal muscle repair in a mouse model of nemaline myopathy.

Sanoudou D, Corbett MA, Han M, Ghoddusi M, Nguyen MA, Vlahovich N, Hardeman EC, Beggs AH.

Hum Mol Genet. 2006 Sep 1;15(17):2603-12. Epub 2006 Jul 28.


Muscle weakness in a mouse model of nemaline myopathy can be reversed with exercise and reveals a novel myofiber repair mechanism.

Joya JE, Kee AJ, Nair-Shalliker V, Ghoddusi M, Nguyen MA, Luther P, Hardeman EC.

Hum Mol Genet. 2004 Nov 1;13(21):2633-45. Epub 2004 Sep 14.


Sorting of a nonmuscle tropomyosin to a novel cytoskeletal compartment in skeletal muscle results in muscular dystrophy.

Kee AJ, Schevzov G, Nair-Shalliker V, Robinson CS, Vrhovski B, Ghoddusi M, Qiu MR, Lin JJ, Weinberger R, Gunning PW, Hardeman EC.

J Cell Biol. 2004 Aug 30;166(5):685-96.


Characterisation of three novel canine osteosarcoma cell lines producing high levels of matrix metalloproteinases.

Loukopoulos P, O'Brien T, Ghoddusi M, Mungall BA, Robinson WF.

Res Vet Sci. 2004 Oct;77(2):131-41.


C2C12 co-culture on a fibroblast substratum enables sustained survival of contractile, highly differentiated myotubes with peripheral nuclei and adult fast myosin expression.

Cooper ST, Maxwell AL, Kizana E, Ghoddusi M, Hardeman EC, Alexander IE, Allen DG, North KN.

Cell Motil Cytoskeleton. 2004 Jul;58(3):200-11.


Occlusable corneas in toadfishes: light transmission, movement and ultrastruture of pigment during light- and dark-adaptation.

Siebeck UE, Collin SP, Ghoddusi M, Marshall NJ.

J Exp Biol. 2003 Jul;206(Pt 13):2177-90.


Renal pathology of polycystic kidney disease and concurrent hereditary nephritis in Bull Terriers.

O'Leary CA, Ghoddusi M, Huxtable CR.

Aust Vet J. 2002 Jun;80(6):353-61.


Role of capsule in the pathogenesis of fowl cholera caused by Pasteurella multocida serogroup A.

Chung JY, Wilkie I, Boyce JD, Townsend KM, Frost AJ, Ghoddusi M, Adler B.

Infect Immun. 2001 Apr;69(4):2487-92.


An apparent outbreak of cutaneous papillomatosis in merino sheep in patagonia, Argentina.

Uzal FA, Latorraca A, Ghoddusi M, Horn M, Adamson M, Kelly WR, Schenkel R.

Vet Res Commun. 2000 Apr;24(3):197-202.


Comparison of the effects of Clostridium perfringens type D culture supernates in ligated intestinal loops of goats and sheep.

Uzal FA, Ghoddusi M, Kelly WR, Rozmanec M.

J Comp Pathol. 1999 Aug;121(2):127-38.


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