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Items: 16


Myosin IIA interacts with the spectrin-actin membrane skeleton to control red blood cell membrane curvature and deformability.

Smith AS, Nowak RB, Zhou S, Giannetto M, Gokhin DS, Papoin J, Ghiran IC, Blanc L, Wan J, Fowler VM.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4377-E4385. doi: 10.1073/pnas.1718285115. Epub 2018 Apr 2. Erratum in: Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6385.


A Novel Implementation of Magnetic Levitation to Quantify Leukocyte Size, Morphology, and Magnetic Properties to Identify Patients with Sepsis.

Andersen MS, Lu S, Lopez GJ, Lassen AT, Shapiro NI, Ghiran IC.

Shock. 2018 Mar 20. doi: 10.1097/SHK.0000000000001139. [Epub ahead of print]


Detection and quantification of subtle changes in red blood cell density using a cell phone.

Felton EJ, Velasquez A, Lu S, Murphy RO, ElKhal A, Mazor O, Gorelik P, Sharda A, Ghiran IC.

Lab Chip. 2016 Aug 16;16(17):3286-95. doi: 10.1039/c6lc00415f.


Ligation of Glycophorin A Generates Reactive Oxygen Species Leading to Decreased Red Blood Cell Function.

Khoory J, Estanislau J, Elkhal A, Lazaar A, Melhorn MI, Brodsky A, Illigens B, Hamachi I, Kurishita Y, Ivanov AR, Shevkoplyas S, Shapiro NI, Ghiran IC.

PLoS One. 2016 Jan 19;11(1):e0141206. doi: 10.1371/journal.pone.0141206. eCollection 2016.


Sickle cell detection using a smartphone.

Knowlton SM, Sencan I, Aytar Y, Khoory J, Heeney MM, Ghiran IC, Tasoglu S.

Sci Rep. 2015 Oct 22;5:15022. doi: 10.1038/srep15022.


Smart-Phone Based Magnetic Levitation for Measuring Densities.

Knowlton S, Yu CH, Jain N, Ghiran IC, Tasoglu S.

PLoS One. 2015 Aug 26;10(8):e0134400. doi: 10.1371/journal.pone.0134400. eCollection 2015.


Levitational Image Cytometry with Temporal Resolution.

Tasoglu S, Khoory JA, Tekin HC, Thomas C, Karnoub AE, Ghiran IC, Demirci U.

Adv Mater. 2015 Jul 8;27(26):3901-8. doi: 10.1002/adma.201405660. Epub 2015 Jun 8.


Dynamic actin filaments control the mechanical behavior of the human red blood cell membrane.

Gokhin DS, Nowak RB, Khoory JA, Piedra Ade L, Ghiran IC, Fowler VM.

Mol Biol Cell. 2015 May 1;26(9):1699-710. doi: 10.1091/mbc.E14-12-1583. Epub 2015 Feb 25.


C4d deposits on the surface of RBCs in trauma patients and interferes with their function.

Muroya T, Kannan L, Ghiran IC, Shevkoplyas SS, Paz Z, Tsokos M, Dalle Lucca JJ, Shapiro NI, Tsokos GC.

Crit Care Med. 2014 May;42(5):e364-72. doi: 10.1097/CCM.0000000000000231.


CR1-mediated ATP release by human red blood cells promotes CR1 clustering and modulates the immune transfer process.

Melhorn MI, Brodsky AS, Estanislau J, Khoory JA, Illigens B, Hamachi I, Kurishita Y, Fraser AD, Nicholson-Weller A, Dolmatova E, Duffy HS, Ghiran IC.

J Biol Chem. 2013 Oct 25;288(43):31139-53. doi: 10.1074/jbc.M113.486035. Epub 2013 Sep 10.


Complement fragment C3d is colocalized within the lipid rafts of T cells and promotes cytokine production.

Borschukova O, Paz Z, Ghiran IC, Liu CC, Kao AH, Manzi S, Ahearn JM, Tsokos GC.

Lupus. 2012 Oct;21(12):1294-304. Epub 2012 Jul 31.


Systemic lupus erythematosus serum deposits C4d on red blood cells, decreases red blood cell membrane deformability, and promotes nitric oxide production.

Ghiran IC, Zeidel ML, Shevkoplyas SS, Burns JM, Tsokos GC, Kyttaris VC.

Arthritis Rheum. 2011 Feb;63(2):503-12. doi: 10.1002/art.30143.


Introduction to fluorescence microscopy.

Ghiran IC.

Methods Mol Biol. 2011;689:93-136. doi: 10.1007/978-1-60761-950-5_7.


Ligation of complement receptor 1 increases erythrocyte membrane deformability.

Glodek AM, Mirchev R, Golan DE, Khoory JA, Burns JM, Shevkoplyas SS, Nicholson-Weller A, Ghiran IC.

Blood. 2010 Dec 23;116(26):6063-71. doi: 10.1182/blood-2010-04-273904. Epub 2010 Sep 22.


Light-scattering spectroscopy differentiates fetal from adult nucleated red blood cells: may lead to noninvasive prenatal diagnosis.

Lim KH, Salahuddin S, Qiu L, Fang H, Vitkin E, Ghiran IC, Modell MD, Takoudes T, Itzkan I, Hanlon EB, Sachs BP, Perelman LT.

Opt Lett. 2009 May 1;34(9):1483-5.


Confocal light absorption and scattering spectroscopic microscopy monitors organelles in live cells with no exogenous labels.

Itzkan I, Qiu L, Fang H, Zaman MM, Vitkin E, Ghiran IC, Salahuddin S, Modell M, Andersson C, Kimerer LM, Cipolloni PB, Lim KH, Freedman SD, Bigio I, Sachs BP, Hanlon EB, Perelman LT.

Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17255-60. Epub 2007 Oct 23.

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