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Items: 1 to 50 of 57

1.

High-fidelity detection and sorting of nanoscale vesicles in viral disease and cancer.

Morales-Kastresana A, Musich TA, Welsh JA, Telford W, Demberg T, Wood JCS, Bigos M, Ross CD, Kachynski A, Dean A, Felton EJ, Van Dyke J, Tigges J, Toxavidis V, Parks DR, Overton WR, Kesarwala AH, Freeman GJ, Rosner A, Perfetto SP, Pasquet L, Terabe M, McKinnon K, Kapoor V, Trepel JB, Puri A, Kobayashi H, Yung B, Chen X, Guion P, Choyke P, Knox SJ, Ghiran I, Robert-Guroff M, Berzofsky JA, Jones JC.

J Extracell Vesicles. 2019 Jun 19;8(1):1597603. doi: 10.1080/20013078.2019.1597603. eCollection 2019.

2.

Erratum: Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling.

Giraldez MD, Spengler RM, Etheridge A, Godoy PM, Barczak AJ, Srinivasan S, Hoff PL, Tanriverdi K, Courtright A, Lu S, Khoory J, Rubio R, Baxter D, Driedonks TAP, Buermans HPJ, Hoen ENMN, Jiang H, Wang K, Ghiran I, Wang YE, Keuren-Jensen KV, Freedman JE, Woodruff PG, Laurent LC, Erle DJ, Galas DJ, Tewari M.

Nat Biotechnol. 2018 Sep 6;36(9):899. doi: 10.1038/nbt0918-899b. No abstract available.

3.

Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling.

Giraldez MD, Spengler RM, Etheridge A, Godoy PM, Barczak AJ, Srinivasan S, De Hoff PL, Tanriverdi K, Courtright A, Lu S, Khoory J, Rubio R, Baxter D, Driedonks TAP, Buermans HPJ, Nolte-'t Hoen ENM, Jiang H, Wang K, Ghiran I, Wang YE, Van Keuren-Jensen K, Freedman JE, Woodruff PG, Laurent LC, Erle DJ, Galas DJ, Tewari M.

Nat Biotechnol. 2018 Sep;36(8):746-757. doi: 10.1038/nbt.4183. Epub 2018 Jul 16.

4.

Myosin IIA interacts with the spectrin-actin membrane skeleton to control red blood cell membrane curvature and deformability.

Smith AS, Nowak RB, Zhou S, Giannetto M, Gokhin DS, Papoin J, Ghiran IC, Blanc L, Wan J, Fowler VM.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4377-E4385. doi: 10.1073/pnas.1718285115. Epub 2018 Apr 2. Erratum in: Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6385.

5.

A Novel Implementation of Magnetic Levitation to Quantify Leukocyte Size, Morphology, and Magnetic Properties to Identify Patients With Sepsis.

Andersen MS, Lu S, Lopez GJ, Lassen AT, Shapiro NI, Ghiran IC.

Shock. 2019 Feb;51(2):147-152. doi: 10.1097/SHK.0000000000001139.

PMID:
29561389
6.

Mast cells regulate CD4+ T-cell differentiation in the absence of antigen presentation.

Rodriguez Cetina Biefer H, Heinbokel T, Uehara H, Camacho V, Minami K, Nian Y, Koduru S, El Fatimy R, Ghiran I, Trachtenberg AJ, de la Fuente MA, Azuma H, Akbari O, Tullius SG, Vasudevan A, Elkhal A.

J Allergy Clin Immunol. 2018 Dec;142(6):1894-1908.e7. doi: 10.1016/j.jaci.2018.01.038. Epub 2018 Feb 20.

7.

Malaria infected red blood cells release small regulatory RNAs through extracellular vesicles.

Babatunde KA, Mbagwu S, Hernández-Castañeda MA, Adapa SR, Walch M, Filgueira L, Falquet L, Jiang RHY, Ghiran I, Mantel PY.

Sci Rep. 2018 Jan 17;8(1):884. doi: 10.1038/s41598-018-19149-9.

8.

Small RNA-seq during acute maximal exercise reveal RNAs involved in vascular inflammation and cardiometabolic health: brief report.

Shah R, Yeri A, Das A, Courtright-Lim A, Ziegler O, Gervino E, Ocel J, Quintero-Pinzon P, Wooster L, Bailey CS, Tanriverdi K, Beaulieu LM, Freedman JE, Ghiran I, Lewis GD, Van Keuren-Jensen K, Das S.

Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1162-H1167. doi: 10.1152/ajpheart.00500.2017. Epub 2017 Sep 15.

9.

Detection of membrane-bound and soluble antigens by magnetic levitation.

Andersen MS, Howard E, Lu S, Richard M, Gregory M, Ogembo G, Mazor O, Gorelik P, Shapiro NI, Sharda AV, Ghiran I.

Lab Chip. 2017 Oct 11;17(20):3462-3473. doi: 10.1039/c7lc00402h.

10.

Red Blood Cells: A Source of Extracellular Vesicles.

Kuo WP, Tigges JC, Toxavidis V, Ghiran I.

Methods Mol Biol. 2017;1660:15-22. doi: 10.1007/978-1-4939-7253-1_2. Review.

PMID:
28828644
11.

Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury.

Bei Y, Xu T, Lv D, Yu P, Xu J, Che L, Das A, Tigges J, Toxavidis V, Ghiran I, Shah R, Li Y, Zhang Y, Das S, Xiao J.

Basic Res Cardiol. 2017 Jul;112(4):38. doi: 10.1007/s00395-017-0628-z. Epub 2017 May 22.

12.

DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress.

Simonson B, Subramanya V, Chan MC, Zhang A, Franchino H, Ottaviano F, Mishra MK, Knight AC, Hunt D, Ghiran I, Khurana TS, Kontaridis MI, Rosenzweig A, Das S.

Sci Signal. 2017 Feb 28;10(468). pii: eaaf5967. doi: 10.1126/scisignal.aaf5967.

13.

Extracellular Microvesicle Production by Human Eosinophils Activated by "Inflammatory" Stimuli.

Akuthota P, Carmo LA, Bonjour K, Murphy RO, Silva TP, Gamalier JP, Capron KL, Tigges J, Toxavidis V, Camacho V, Ghiran I, Ueki S, Weller PF, Melo RC.

Front Cell Dev Biol. 2016 Oct 27;4:117. eCollection 2016.

14.

Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria.

Mantel PY, Hjelmqvist D, Walch M, Kharoubi-Hess S, Nilsson S, Ravel D, Ribeiro M, Grüring C, Ma S, Padmanabhan P, Trachtenberg A, Ankarklev J, Brancucci NM, Huttenhower C, Duraisingh MT, Ghiran I, Kuo WP, Filgueira L, Martinelli R, Marti M.

Nat Commun. 2016 Oct 10;7:12727. doi: 10.1038/ncomms12727.

15.

Detection and quantification of subtle changes in red blood cell density using a cell phone.

Felton EJ, Velasquez A, Lu S, Murphy RO, ElKhal A, Mazor O, Gorelik P, Sharda A, Ghiran IC.

Lab Chip. 2016 Aug 16;16(17):3286-95. doi: 10.1039/c6lc00415f.

PMID:
27431921
16.

NAD(+) regulates Treg cell fate and promotes allograft survival via a systemic IL-10 production that is CD4(+) CD25(+) Foxp3(+) T cells independent.

Elkhal A, Rodriguez Cetina Biefer H, Heinbokel T, Uehara H, Quante M, Seyda M, Schuitenmaker JM, Krenzien F, Camacho V, de la Fuente MA, Ghiran I, Tullius SG.

Sci Rep. 2016 Mar 1;6:22325. doi: 10.1038/srep22325.

17.

Ligation of Glycophorin A Generates Reactive Oxygen Species Leading to Decreased Red Blood Cell Function.

Khoory J, Estanislau J, Elkhal A, Lazaar A, Melhorn MI, Brodsky A, Illigens B, Hamachi I, Kurishita Y, Ivanov AR, Shevkoplyas S, Shapiro NI, Ghiran IC.

PLoS One. 2016 Jan 19;11(1):e0141206. doi: 10.1371/journal.pone.0141206. eCollection 2016.

18.

Diurnal Variations of Circulating Extracellular Vesicles Measured by Nano Flow Cytometry.

Danielson KM, Estanislau J, Tigges J, Toxavidis V, Camacho V, Felton EJ, Khoory J, Kreimer S, Ivanov AR, Mantel PY, Jones J, Akuthota P, Das S, Ghiran I.

PLoS One. 2016 Jan 8;11(1):e0144678. doi: 10.1371/journal.pone.0144678. eCollection 2016.

19.

Sickle cell detection using a smartphone.

Knowlton SM, Sencan I, Aytar Y, Khoory J, Heeney MM, Ghiran IC, Tasoglu S.

Sci Rep. 2015 Oct 22;5:15022. doi: 10.1038/srep15022.

20.

Potential functional applications of extracellular vesicles: a report by the NIH Common Fund Extracellular RNA Communication Consortium.

Quesenberry PJ, Aliotta J, Camussi G, Abdel-Mageed AB, Wen S, Goldberg L, Zhang HG, Tetta C, Franklin J, Coffey RJ, Danielson K, Subramanya V, Ghiran I, Das S, Chen CC, Pusic KM, Pusic AD, Chatterjee D, Kraig RP, Balaj L, Dooner M.

J Extracell Vesicles. 2015 Aug 28;4:27575. doi: 10.3402/jev.v4.27575. eCollection 2015.

21.

Smart-Phone Based Magnetic Levitation for Measuring Densities.

Knowlton S, Yu CH, Jain N, Ghiran IC, Tasoglu S.

PLoS One. 2015 Aug 26;10(8):e0134400. doi: 10.1371/journal.pone.0134400. eCollection 2015.

22.

Magnetic levitation of single cells.

Durmus NG, Tekin HC, Guven S, Sridhar K, Arslan Yildiz A, Calibasi G, Ghiran I, Davis RW, Steinmetz LM, Demirci U.

Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):E3661-8. doi: 10.1073/pnas.1509250112. Epub 2015 Jun 29.

23.

Levitational Image Cytometry with Temporal Resolution.

Tasoglu S, Khoory JA, Tekin HC, Thomas C, Karnoub AE, Ghiran IC, Demirci U.

Adv Mater. 2015 Jul 8;27(26):3901-8. doi: 10.1002/adma.201405660. Epub 2015 Jun 8.

24.

Mass-spectrometry-based molecular characterization of extracellular vesicles: lipidomics and proteomics.

Kreimer S, Belov AM, Ghiran I, Murthy SK, Frank DA, Ivanov AR.

J Proteome Res. 2015 Jun 5;14(6):2367-84. doi: 10.1021/pr501279t. Epub 2015 May 14. Review.

PMID:
25927954
25.

Dynamic actin filaments control the mechanical behavior of the human red blood cell membrane.

Gokhin DS, Nowak RB, Khoory JA, Piedra Ade L, Ghiran IC, Fowler VM.

Mol Biol Cell. 2015 May 1;26(9):1699-710. doi: 10.1091/mbc.E14-12-1583. Epub 2015 Feb 25.

26.

NAD+ protects against EAE by regulating CD4+ T-cell differentiation.

Tullius SG, Biefer HR, Li S, Trachtenberg AJ, Edtinger K, Quante M, Krenzien F, Uehara H, Yang X, Kissick HT, Kuo WP, Ghiran I, de la Fuente MA, Arredouani MS, Camacho V, Tigges JC, Toxavidis V, El Fatimy R, Smith BD, Vasudevan A, ElKhal A.

Nat Commun. 2014 Oct 7;5:5101. doi: 10.1038/ncomms6101.

27.

Bio-inspired cryo-ink preserves red blood cell phenotype and function during nanoliter vitrification.

El Assal R, Guven S, Gurkan UA, Gozen I, Shafiee H, Dalbeyler S, Abdalla N, Thomas G, Fuld W, Illigens BM, Estanislau J, Khoory J, Kaufman R, Zylberberg C, Lindeman N, Wen Q, Ghiran I, Demirci U.

Adv Mater. 2014 Sep 3;26(33):5815-22. doi: 10.1002/adma.201400941. Epub 2014 Jul 22.

28.

C4d deposits on the surface of RBCs in trauma patients and interferes with their function.

Muroya T, Kannan L, Ghiran IC, Shevkoplyas SS, Paz Z, Tsokos M, Dalle Lucca JJ, Shapiro NI, Tsokos GC.

Crit Care Med. 2014 May;42(5):e364-72. doi: 10.1097/CCM.0000000000000231.

29.

CR1-mediated ATP release by human red blood cells promotes CR1 clustering and modulates the immune transfer process.

Melhorn MI, Brodsky AS, Estanislau J, Khoory JA, Illigens B, Hamachi I, Kurishita Y, Fraser AD, Nicholson-Weller A, Dolmatova E, Duffy HS, Ghiran IC.

J Biol Chem. 2013 Oct 25;288(43):31139-53. doi: 10.1074/jbc.M113.486035. Epub 2013 Sep 10.

30.

Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system.

Mantel PY, Hoang AN, Goldowitz I, Potashnikova D, Hamza B, Vorobjev I, Ghiran I, Toner M, Irimia D, Ivanov AR, Barteneva N, Marti M.

Cell Host Microbe. 2013 May 15;13(5):521-534. doi: 10.1016/j.chom.2013.04.009.

31.

Human complement receptor type 1/CD35 is an Epstein-Barr Virus receptor.

Ogembo JG, Kannan L, Ghiran I, Nicholson-Weller A, Finberg RW, Tsokos GC, Fingeroth JD.

Cell Rep. 2013 Feb 21;3(2):371-85. doi: 10.1016/j.celrep.2013.01.023. Epub 2013 Feb 14.

32.

Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans.

Ueki S, Melo RC, Ghiran I, Spencer LA, Dvorak AM, Weller PF.

Blood. 2013 Mar 14;121(11):2074-83. doi: 10.1182/blood-2012-05-432088. Epub 2013 Jan 9.

33.

Complement fragment C3d is colocalized within the lipid rafts of T cells and promotes cytokine production.

Borschukova O, Paz Z, Ghiran IC, Liu CC, Kao AH, Manzi S, Ahearn JM, Tsokos GC.

Lupus. 2012 Oct;21(12):1294-304. Epub 2012 Jul 31.

PMID:
22851413
34.

Systemic lupus erythematosus serum deposits C4d on red blood cells, decreases red blood cell membrane deformability, and promotes nitric oxide production.

Ghiran IC, Zeidel ML, Shevkoplyas SS, Burns JM, Tsokos GC, Kyttaris VC.

Arthritis Rheum. 2011 Feb;63(2):503-12. doi: 10.1002/art.30143.

35.

Introduction to fluorescence microscopy.

Ghiran IC.

Methods Mol Biol. 2011;689:93-136. doi: 10.1007/978-1-60761-950-5_7.

PMID:
21153789
36.

Examining the role of microvesicles to develop prognostic and diagnostic assays.

Ghiran I, Kuo WP.

J Appl Oral Sci. 2010 Sep-Oct;18(5):i. No abstract available.

37.

Ligation of complement receptor 1 increases erythrocyte membrane deformability.

Glodek AM, Mirchev R, Golan DE, Khoory JA, Burns JM, Shevkoplyas SS, Nicholson-Weller A, Ghiran IC.

Blood. 2010 Dec 23;116(26):6063-71. doi: 10.1182/blood-2010-04-273904. Epub 2010 Sep 22.

38.

Complement receptor 1 expression on mouse erythrocytes mediates clearance of Streptococcus pneumoniae by immune adherence.

Li J, Wang JP, Ghiran I, Cerny A, Szalai AJ, Briles DE, Finberg RW.

Infect Immun. 2010 Jul;78(7):3129-35. doi: 10.1128/IAI.01263-09. Epub 2010 May 3.

39.

Helicobacter pylori moves through mucus by reducing mucin viscoelasticity.

Celli JP, Turner BS, Afdhal NH, Keates S, Ghiran I, Kelly CP, Ewoldt RH, McKinley GH, So P, Erramilli S, Bansil R.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14321-6. doi: 10.1073/pnas.0903438106. Epub 2009 Aug 11.

40.

Light-scattering spectroscopy differentiates fetal from adult nucleated red blood cells: may lead to noninvasive prenatal diagnosis.

Lim KH, Salahuddin S, Qiu L, Fang H, Vitkin E, Ghiran IC, Modell MD, Takoudes T, Itzkan I, Hanlon EB, Sachs BP, Perelman LT.

Opt Lett. 2009 May 1;34(9):1483-5.

41.

C3b deposition on human erythrocytes induces the formation of a membrane skeleton-linked protein complex.

Karnchanaphanurach P, Mirchev R, Ghiran I, Asara JM, Papahadjopoulos-Sternberg B, Nicholson-Weller A, Golan DE.

J Clin Invest. 2009 Apr;119(4):788-801. doi: 10.1172/JCI36088. Epub 2009 Mar 2.

42.

Eosinophil granules function extracellularly as receptor-mediated secretory organelles.

Neves JS, Perez SA, Spencer LA, Melo RC, Reynolds L, Ghiran I, Mahmudi-Azer S, Odemuyiwa SO, Dvorak AM, Moqbel R, Weller PF.

Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18478-83. doi: 10.1073/pnas.0804547105. Epub 2008 Nov 18.

43.

Complex dynamics of human red blood cell flickering: alterations with in vivo aging.

Costa M, Ghiran I, Peng CK, Nicholson-Weller A, Goldberger AL.

Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Aug;78(2 Pt 1):020901. Epub 2008 Aug 1.

44.

Ligation of erythrocyte CR1 induces its clustering in complex with scaffolding protein FAP-1.

Ghiran I, Glodek AM, Weaver G, Klickstein LB, Nicholson-Weller A.

Blood. 2008 Oct 15;112(8):3465-73. doi: 10.1182/blood-2008-04-151845. Epub 2008 Aug 6.

45.

Airway eosinophils: allergic inflammation recruited professional antigen-presenting cells.

Wang HB, Ghiran I, Matthaei K, Weller PF.

J Immunol. 2007 Dec 1;179(11):7585-92.

46.

Confocal light absorption and scattering spectroscopic microscopy monitors organelles in live cells with no exogenous labels.

Itzkan I, Qiu L, Fang H, Zaman MM, Vitkin E, Ghiran IC, Salahuddin S, Modell M, Andersson C, Kimerer LM, Cipolloni PB, Lim KH, Freedman SD, Bigio I, Sachs BP, Hanlon EB, Perelman LT.

Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17255-60. Epub 2007 Oct 23.

47.

Antibody CR1-2B11 recognizes a non-polymorphic epitope of human CR1 (CD35).

Chen CH, Ghiran I, Beurskens FJ, Weaver G, Vincent JA, Nicholson-Weller A, Klickstein LB.

Clin Exp Immunol. 2007 Jun;148(3):546-54.

48.

Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors.

Honczarenko M, Le Y, Swierkowski M, Ghiran I, Glodek AM, Silberstein LE.

Stem Cells. 2006 Apr;24(4):1030-41. Epub 2005 Oct 27.

49.

Human eosinophils secrete preformed, granule-stored interleukin-4 through distinct vesicular compartments.

Melo RC, Spencer LA, Perez SA, Ghiran I, Dvorak AM, Weller PF.

Traffic. 2005 Nov;6(11):1047-57.

50.

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