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Items: 1 to 50 of 76

1.

Immunization of BLT Humanized Mice Redirects T Cell Responses to Gag and Reduces Acute HIV-1 Viremia.

Claiborne DT, Dudek TE, Maldini CR, Power KA, Ghebremichael M, Seung E, Mellors EF, Vrbanac VD, Krupp K, Bisesi A, Tager AM, Knipe DM, Boutwell CL, Allen TM.

J Virol. 2019 Sep 30;93(20). pii: e00814-19. doi: 10.1128/JVI.00814-19. Print 2019 Oct 15.

PMID:
31375576
2.

Editor's Note: The Efficacy of the Novel Dual PI3-Kinase/mTOR Inhibitor NVP-BEZ235 Compared with Rapamycin in Renal Cell Carcinoma.

Cho DC, Cohen MB, Panka DJ, Collins M, Ghebremichael M, Atkins MB, Signoretti S, Mier JW.

Clin Cancer Res. 2019 Jul 1;25(13):4194. doi: 10.1158/1078-0432.CCR-19-1601. No abstract available.

PMID:
31263033
3.

Prospective Cohort Study on Performance of Cerebrospinal Fluid (CSF) Xpert MTB/RIF, CSF Lipoarabinomannan (LAM) Lateral Flow Assay (LFA), and Urine LAM LFA for Diagnosis of Tuberculous Meningitis in Zambia.

Siddiqi OK, Birbeck GL, Ghebremichael M, Mubanga E, Love S, Buback C, Kosloff B, Ayles H, Atadzhanov M, Dheda K, Koralnik IJ.

J Clin Microbiol. 2019 Jul 26;57(8). pii: e00652-19. doi: 10.1128/JCM.00652-19. Print 2019 Aug.

PMID:
31189584
4.

Comparing the Diagnostics Accuracy of CD4+ T-Lymphocyte Count and Percent as a Surrogate Markers of Pediatric HIV Disease.

Ghebremichael M, Michael H, Tubbs J, Paintsil E.

J Math Stat. 2019;15(1):55-64. doi: 10.3844/jmssp.2019.55.64. Epub 2019 Apr 3.

5.

Structural topology defines protective CD8+ T cell epitopes in the HIV proteome.

Gaiha GD, Rossin EJ, Urbach J, Landeros C, Collins DR, Nwonu C, Muzhingi I, Anahtar MN, Waring OM, Piechocka-Trocha A, Waring M, Worrall DP, Ghebremichael MS, Newman RM, Power KA, Allen TM, Chodosh J, Walker BD.

Science. 2019 May 3;364(6439):480-484. doi: 10.1126/science.aav5095.

PMID:
31048489
6.

Resistance of HIV-infected macrophages to CD8+ T lymphocyte-mediated killing drives activation of the immune system.

Clayton KL, Collins DR, Lengieza J, Ghebremichael M, Dotiwala F, Lieberman J, Walker BD.

Nat Immunol. 2018 May;19(5):475-486. doi: 10.1038/s41590-018-0085-3. Epub 2018 Apr 18.

7.

Viral control in chronic HIV-1 subtype C infection is associated with enrichment of p24 IgG1 with Fc effector activity.

Chung AW, Mabuka JM, Ndlovu B, Licht A, Robinson H, Ramlakhan Y, Ghebremichael M, Reddy T, Goulder PJR, Walker BD, Ndung'u T, Alter G.

AIDS. 2018 Jun 19;32(10):1207-1217. doi: 10.1097/QAD.0000000000001812.

8.

The ROC curve for regularly measured longitudinal biomarkers.

Michael H, Tian L, Ghebremichael M.

Biostatistics. 2019 Jul 1;20(3):433-451. doi: 10.1093/biostatistics/kxy010.

PMID:
29608649
9.

Detection and treatment of Fiebig stage I HIV-1 infection in young at-risk women in South Africa: a prospective cohort study.

Dong KL, Moodley A, Kwon DS, Ghebremichael MS, Dong M, Ismail N, Ndhlovu ZM, Mabuka JM, Muema DM, Pretorius K, Lin N, Walker BD, Ndung'u T.

Lancet HIV. 2018 Jan;5(1):e35-e44. doi: 10.1016/S2352-3018(17)30146-7. Epub 2017 Oct 1.

10.

Upregulation of Apoptosis Pathway Genes in Peripheral Blood Mononuclear Cells of HIV-Infected Individuals with Antiretroviral Therapy-Associated Mitochondrial Toxicity.

Foli Y, Ghebremichael M, Li M, Paintsil E.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00522-17. doi: 10.1128/AAC.00522-17. Print 2017 Aug.

11.

Lactobacillus-Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women.

Gosmann C, Anahtar MN, Handley SA, Farcasanu M, Abu-Ali G, Bowman BA, Padavattan N, Desai C, Droit L, Moodley A, Dong M, Chen Y, Ismail N, Ndung'u T, Ghebremichael MS, Wesemann DR, Mitchell C, Dong KL, Huttenhower C, Walker BD, Virgin HW, Kwon DS.

Immunity. 2017 Jan 17;46(1):29-37. doi: 10.1016/j.immuni.2016.12.013. Epub 2017 Jan 10.

12.

A Functional Role for Antibodies in Tuberculosis.

Lu LL, Chung AW, Rosebrock TR, Ghebremichael M, Yu WH, Grace PS, Schoen MK, Tafesse F, Martin C, Leung V, Mahan AE, Sips M, Kumar MP, Tedesco J, Robinson H, Tkachenko E, Draghi M, Freedberg KJ, Streeck H, Suscovich TJ, Lauffenburger DA, Restrepo BI, Day C, Fortune SM, Alter G.

Cell. 2016 Oct 6;167(2):433-443.e14. doi: 10.1016/j.cell.2016.08.072. Epub 2016 Sep 22.

13.

HLA-C levels impact natural killer cell subset distribution and function.

Sips M, Liu Q, Draghi M, Ghebremichael M, Berger CT, Suscovich TJ, Sun Y, Walker BD, Carrington M, Altfeld M, Brouckaert P, De Jager PL, Alter G.

Hum Immunol. 2016 Dec;77(12):1147-1153. doi: 10.1016/j.humimm.2016.08.004. Epub 2016 Aug 10.

14.

Elite controller CD8+ T cells exhibit comparable viral inhibition capacity, but better sustained effector properties compared to chronic progressors.

Shasha D, Karel D, Angiuli O, Greenblatt A, Ghebremichael M, Yu X, Porichis F, Walker BD.

J Leukoc Biol. 2016 Dec;100(6):1425-1433. Epub 2016 Jul 12.

15.

Frequent Episodes of Detectable Viremia in HIV Treatment-Experienced Children is Associated with a Decline in CD4+ T-cells Over Time.

Paintsil E, Martin R, Goldenthal A, Bhandari S, Andiman W, Ghebremichael M.

J AIDS Clin Res. 2016 Apr;7(4). pii: 565. doi: 10.4172/2155-6113.1000565. Epub 2016 Apr 14.

16.

Protection of Humanized Mice From Repeated Intravaginal HIV Challenge by Passive Immunization: A Model for Studying the Efficacy of Neutralizing Antibodies In Vivo.

Deruaz M, Moldt B, Le KM, Power KA, Vrbanac VD, Tanno S, Ghebremichael MS, Allen TM, Tager AM, Burton DR, Luster AD.

J Infect Dis. 2016 Aug 15;214(4):612-6. doi: 10.1093/infdis/jiw203. Epub 2016 Jun 29.

17.

Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus.

Tully DC, Ogilvie CB, Batorsky RE, Bean DJ, Power KA, Ghebremichael M, Bedard HE, Gladden AD, Seese AM, Amero MA, Lane K, McGrath G, Bazner SB, Tinsley J, Lennon NJ, Henn MR, Brumme ZL, Norris PJ, Rosenberg ES, Mayer KH, Jessen H, Kosakovsky Pond SL, Walker BD, Altfeld M, Carlson JM, Allen TM.

PLoS Pathog. 2016 May 10;12(5):e1005619. doi: 10.1371/journal.ppat.1005619. eCollection 2016 May.

18.

A Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis.

Abers MS, Ghebremichael MS, Timmons AK, Warren HS, Poznansky MC, Vyas JM.

Open Forum Infect Dis. 2016 Feb 12;3(1):ofw036. doi: 10.1093/ofid/ofw036. eCollection 2016 Jan.

19.

Altered Virome and Bacterial Microbiome in Human Immunodeficiency Virus-Associated Acquired Immunodeficiency Syndrome.

Monaco CL, Gootenberg DB, Zhao G, Handley SA, Ghebremichael MS, Lim ES, Lankowski A, Baldridge MT, Wilen CB, Flagg M, Norman JM, Keller BC, Luévano JM, Wang D, Boum Y, Martin JN, Hunt PW, Bangsberg DR, Siedner MJ, Kwon DS, Virgin HW.

Cell Host Microbe. 2016 Mar 9;19(3):311-22. doi: 10.1016/j.chom.2016.02.011.

20.

Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategies.

Sips M, Krykbaeva M, Diefenbach TJ, Ghebremichael M, Bowman BA, Dugast AS, Boesch AW, Streeck H, Kwon DS, Ackerman ME, Suscovich TJ, Brouckaert P, Schacker TW, Alter G.

Mucosal Immunol. 2016 Nov;9(6):1584-1595. doi: 10.1038/mi.2016.12. Epub 2016 Feb 17.

21.

Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective cohort study.

Byrne EH, Anahtar MN, Cohen KE, Moodley A, Padavattan N, Ismail N, Bowman BA, Olson GS, Mabhula A, Leslie A, Ndung'u T, Walker BD, Ghebremichael MS, Dong KL, Kwon DS.

Lancet Infect Dis. 2016 Apr;16(4):441-8. doi: 10.1016/S1473-3099(15)00429-6. Epub 2015 Dec 24.

22.

HIV-1 Antibody Neutralization Breadth Is Associated with Enhanced HIV-Specific CD4+ T Cell Responses.

Ranasinghe S, Soghoian DZ, Lindqvist M, Ghebremichael M, Donaghey F, Carrington M, Seaman MS, Kaufmann DE, Walker BD, Porichis F.

J Virol. 2015 Dec 9;90(5):2208-20. doi: 10.1128/JVI.02278-15.

23.

Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point.

Ndhlovu ZM, Kamya P, Mewalal N, Kløverpris HN, Nkosi T, Pretorius K, Laher F, Ogunshola F, Chopera D, Shekhar K, Ghebremichael M, Ismail N, Moodley A, Malik A, Leslie A, Goulder PJ, Buus S, Chakraborty A, Dong K, Ndung'u T, Walker BD.

Immunity. 2015 Sep 15;43(3):591-604. doi: 10.1016/j.immuni.2015.08.012. Epub 2015 Sep 8.

24.

Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract.

Anahtar MN, Byrne EH, Doherty KE, Bowman BA, Yamamoto HS, Soumillon M, Padavattan N, Ismail N, Moodley A, Sabatini ME, Ghebremichael MS, Nusbaum C, Huttenhower C, Virgin HW, Ndung'u T, Dong KL, Walker BD, Fichorova RN, Kwon DS.

Immunity. 2015 May 19;42(5):965-76. doi: 10.1016/j.immuni.2015.04.019.

25.

Co-infection with Mycobacterium tuberculosis impairs HIV-Specific CD8+ and CD4+ T cell functionality.

Chetty S, Govender P, Zupkosky J, Pillay M, Ghebremichael M, Moosa MY, Ndung'u T, Porichis F, Kasprowicz VO.

PLoS One. 2015 Mar 17;10(3):e0118654. doi: 10.1371/journal.pone.0118654. eCollection 2015. Erratum in: PLoS One. 2015 May 20;10 (5):e0127763.

26.

'Poisonous, filthy, loathsome, damnable stuff': the rhetorical ecology of vaccination concern.

Hausman BL, Ghebremichael M, Hayek P, Mack E.

Yale J Biol Med. 2014 Dec 12;87(4):403-16. eCollection 2014 Dec.

27.

Different antigen-processing activities in dendritic cells, macrophages, and monocytes lead to uneven production of HIV epitopes and affect CTL recognition.

Dinter J, Gourdain P, Lai NY, Duong E, Bracho-Sanchez E, Rucevic M, Liebesny PH, Xu Y, Shimada M, Ghebremichael M, Kavanagh DG, Le Gall S.

J Immunol. 2014 Nov 1;193(9):4322-4334. doi: 10.4049/jimmunol.1400491. Epub 2014 Sep 17.

28.

Tuberculosis distorts the inhibitory impact of interleukin-10 in HIV infection.

Chetty S, Porichis F, Govender P, Zupkosky J, Ghebremichael M, Pillay M, Walker BD, Ndung'u T, Kaufmann DE, Kasprowicz VO.

AIDS. 2014 Nov 28;28(18):2671-6. doi: 10.1097/QAD.0000000000000437.

29.

Chronic HCV infection affects the NK cell phenotype in the blood more than in the liver.

Cosgrove C, Berger CT, Kroy DC, Cheney PC, Ghebremichael M, Aneja J, Tomlinson M, Kim AY, Lauer GM, Alter G.

PLoS One. 2014 Aug 22;9(8):e105950. doi: 10.1371/journal.pone.0105950. eCollection 2014.

30.

Induction cetuximab, paclitaxel, and carboplatin followed by chemoradiation with cetuximab, paclitaxel, and carboplatin for stage III/IV head and neck squamous cancer: a phase II ECOG-ACRIN trial (E2303).

Wanebo HJ, Lee J, Burtness BA, Ridge JA, Ghebremichael M, Spencer SA, Psyrri D, Pectasides E, Rimm D, Rosen FR, Hancock MR, Tolba KA, Forastiere AA.

Ann Oncol. 2014 Oct;25(10):2036-41. doi: 10.1093/annonc/mdu248. Epub 2014 Jul 9.

31.

Lack of protection following passive transfer of polyclonal highly functional low-dose non-neutralizing antibodies.

Dugast AS, Chan Y, Hoffner M, Licht A, Nkolola J, Li H, Streeck H, Suscovich TJ, Ghebremichael M, Ackerman ME, Barouch DH, Alter G.

PLoS One. 2014 May 12;9(5):e97229. doi: 10.1371/journal.pone.0097229. eCollection 2014.

32.

Prognostic significance of human papillomavirus in recurrent or metastatic head and neck cancer: an analysis of Eastern Cooperative Oncology Group trials.

Argiris A, Li S, Ghebremichael M, Egloff AM, Wang L, Forastiere AA, Burtness B, Mehra R.

Ann Oncol. 2014 Jul;25(7):1410-6. doi: 10.1093/annonc/mdu167. Epub 2014 May 5.

33.

The Syndromic versus Laboratory Diagnosis of Sexually Transmitted Infections in Resource-Limited Settings.

Ghebremichael M.

ISRN AIDS. 2014 Mar 5;2014:103452. doi: 10.1155/2014/103452. eCollection 2014.

34.

Molecular diagnosis of central nervous system opportunistic infections in HIV-infected Zambian adults.

Siddiqi OK, Ghebremichael M, Dang X, Atadzhanov M, Kaonga P, Khoury MN, Koralnik IJ.

Clin Infect Dis. 2014 Jun;58(12):1771-7. doi: 10.1093/cid/ciu191. Epub 2014 Mar 25.

35.

HIV-1 infection impairs regulatory T-cell suppressive capacity on a per-cell basis.

Angin M, Sharma S, King M, Murooka TT, Ghebremichael M, Mempel TR, Walker BD, Bhasin MK, Addo MM.

J Infect Dis. 2014 Sep 15;210(6):899-903. doi: 10.1093/infdis/jiu188. Epub 2014 Mar 23.

36.

Polyfunctional Fc-effector profiles mediated by IgG subclass selection distinguish RV144 and VAX003 vaccines.

Chung AW, Ghebremichael M, Robinson H, Brown E, Choi I, Lane S, Dugast AS, Schoen MK, Rolland M, Suscovich TJ, Mahan AE, Liao L, Streeck H, Andrews C, Rerks-Ngarm S, Nitayaphan S, de Souza MS, Kaewkungwal J, Pitisuttithum P, Francis D, Michael NL, Kim JH, Bailey-Kellogg C, Ackerman ME, Alter G.

Sci Transl Med. 2014 Mar 19;6(228):228ra38. doi: 10.1126/scitranslmed.3007736.

37.

Antiretroviral therapy-induced mitochondrial toxicity: potential mechanisms beyond polymerase-γ inhibition.

Selvaraj S, Ghebremichael M, Li M, Foli Y, Langs-Barlow A, Ogbuagu A, Barakat L, Tubridy E, Edifor R, Lam W, Cheng YC, Paintsil E.

Clin Pharmacol Ther. 2014 Jul;96(1):110-20. doi: 10.1038/clpt.2014.64. Epub 2014 Mar 17.

38.

Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection.

Vaidya SA, Streeck H, Beckwith N, Ghebremichael M, Pereyra F, Kwon DS, Addo MM, Rychert J, Routy JP, Jessen H, Kelleher AD, Hecht F, Sekaly RP, Carrington M, Walker BD, Allen TM, Rosenberg ES, Altfeld M.

Retrovirology. 2013 Nov 18;10:139. doi: 10.1186/1742-4690-10-139.

39.

A phase II study of bevacizumab and high-dose interleukin-2 in patients with metastatic renal cell carcinoma: a Cytokine Working Group (CWG) study.

Dandamudi UB, Ghebremichael M, Sosman JA, Clark JI, McDermott DF, Atkins MB, Dutcher JP, Urba WJ, Regan MM, Puzanov I, Crocenzi TS, Curti BD, Vaishampayan UN, Crosby NA, Margolin KA, Ernstoff MS.

J Immunother. 2013 Nov-Dec;36(9):490-5. doi: 10.1097/CJI.0000000000000003.

PMID:
24145360
40.

Phase III randomized, placebo-controlled trial of docetaxel with or without gefitinib in recurrent or metastatic head and neck cancer: an eastern cooperative oncology group trial.

Argiris A, Ghebremichael M, Gilbert J, Lee JW, Sachidanandam K, Kolesar JM, Burtness B, Forastiere AA.

J Clin Oncol. 2013 Apr 10;31(11):1405-14. doi: 10.1200/JCO.2012.45.4272. Epub 2013 Mar 4.

41.

No effect of adjunctive, repeated-dose intranasal insulin treatment on psychopathology and cognition in patients with schizophrenia.

Fan X, Liu E, Freudenreich O, Copeland P, Hayden D, Ghebremichael M, Cohen B, Ongur D, Goff DC, Henderson DC.

J Clin Psychopharmacol. 2013 Apr;33(2):226-30. doi: 10.1097/JCP.0b013e31828701d0.

42.
43.

Preserved function of regulatory T cells in chronic HIV-1 infection despite decreased numbers in blood and tissue.

Angin M, Kwon DS, Streeck H, Wen F, King M, Rezai A, Law K, Hongo TC, Pyo A, Piechocka-Trocha A, Toth I, Pereyra F, Ghebremichael M, Rodig SJ, Milner DA Jr, Richter JM, Altfeld M, Kaufmann DE, Walker BD, Addo MM.

J Infect Dis. 2012 May 15;205(10):1495-500. doi: 10.1093/infdis/jis236. Epub 2012 Mar 15.

44.

Factors predicting discordant virological and immunological responses to antiretroviral therapy in HIV-1 clade C infected Zulu/Xhosa in South Africa.

Julg B, Poole D, Ghebremichael M, Castilla C, Altfeld M, Sunpath H, Murphy RA, Walker BD.

PLoS One. 2012;7(2):e31161. doi: 10.1371/journal.pone.0031161. Epub 2012 Feb 14.

45.
46.

Use of dried blood spots for the determination of genetic variation of interleukin-10, killer immunoglobulin-like receptor and HLA class I genes.

Ndlovu BG, Danaviah S, Moodley E, Ghebremichael M, Bland R, Viljoen J, Newell ML, Ndung'u T, Carr WH.

Tissue Antigens. 2012 Feb;79(2):114-22. doi: 10.1111/j.1399-0039.2011.01807.x. Epub 2011 Nov 22.

47.

HIV-specific CD4 T cell responses to different viral proteins have discordant associations with viral load and clinical outcome.

Ranasinghe S, Flanders M, Cutler S, Soghoian DZ, Ghebremichael M, Davis I, Lindqvist M, Pereyra F, Walker BD, Heckerman D, Streeck H.

J Virol. 2012 Jan;86(1):277-83. doi: 10.1128/JVI.05577-11. Epub 2011 Oct 26.

48.

Altered distribution of mucosal NK cells during HIV infection.

Sips M, Sciaranghella G, Diefenbach T, Dugast AS, Berger CT, Liu Q, Kwon D, Ghebremichael M, Estes JD, Carrington M, Martin JN, Deeks SG, Hunt PW, Alter G.

Mucosal Immunol. 2012 Jan;5(1):30-40. doi: 10.1038/mi.2011.40. Epub 2011 Oct 12.

49.

High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV control.

Berger CT, Frahm N, Price DA, Mothe B, Ghebremichael M, Hartman KL, Henry LM, Brenchley JM, Ruff LE, Venturi V, Pereyra F, Sidney J, Sette A, Douek DC, Walker BD, Kaufmann DE, Brander C.

J Virol. 2011 Sep;85(18):9334-45. doi: 10.1128/JVI.00460-11. Epub 2011 Jul 13.

50.

Early viral replication in lymph nodes provides HIV with a means by which to escape NK-cell-mediated control.

Luteijn R, Sciaranghella G, van Lunzen J, Nolting A, Dugast AS, Ghebremichael MS, Altfeld M, Alter G.

Eur J Immunol. 2011 Sep;41(9):2729-40. doi: 10.1002/eji.201040886. Epub 2011 Aug 12.

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