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Items: 4

1.

Tissue-Specific Oncogenic Activity of KRASA146T.

Poulin EJ, Bera AK, Lu J, Lin YJ, Strasser SD, Paulo JA, Huang TQ, Morales C, Yan W, Cook J, Nowak JA, Brubaker DK, Joughin BA, Johnson CW, DeStefanis RA, Ghazi PC, Gondi S, Wales TE, Iacob RE, Bogdanova L, Gierut JJ, Li Y, Engen JR, Perez-Mancera PA, Braun BS, Gygi SP, Lauffenburger DA, Westover KD, Haigis KM.

Cancer Discov. 2019 Jun;9(6):738-755. doi: 10.1158/2159-8290.CD-18-1220. Epub 2019 Apr 5.

PMID:
30952657
2.

The colonic epithelium plays an active role in promoting colitis by shaping the tissue cytokine profile.

Lyons J, Ghazi PC, Starchenko A, Tovaglieri A, Baldwin KR, Poulin EJ, Gierut JJ, Genetti C, Yajnik V, Breault DT, Lauffenburger DA, Haigis KM.

PLoS Biol. 2018 Mar 29;16(3):e2002417. doi: 10.1371/journal.pbio.2002417. eCollection 2018 Mar.

3.

Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitis.

Lyons J, Brubaker DK, Ghazi PC, Baldwin KR, Edwards A, Boukhali M, Strasser SD, Suarez-Lopez L, Lin YJ, Yajnik V, Kissil JL, Haas W, Lauffenburger DA, Haigis KM.

Sci Signal. 2018 Feb 27;11(519). pii: eaan3580. doi: 10.1126/scisignal.aan3580.

4.

Simultaneous cytosolic delivery of a chemotherapeutic and siRNA using nanoparticle-stabilized nanocapsules.

Hardie J, Jiang Y, Tetrault ER, Ghazi PC, Tonga GY, Farkas ME, Rotello VM.

Nanotechnology. 2016 Sep 16;27(37):374001. doi: 10.1088/0957-4484/27/37/374001. Epub 2016 Aug 9.

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