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Items: 37

1.

Comprehensive molecular profiling of advanced/metastatic olfactory neuroblastomas.

Topcagic J, Feldman R, Ghazalpour A, Swensen J, Gatalica Z, Vranic S.

PLoS One. 2018 Jan 11;13(1):e0191244. doi: 10.1371/journal.pone.0191244. eCollection 2018.

2.

The Genetic Architecture of Coronary Artery Disease: Current Knowledge and Future Opportunities.

Hartiala J, Schwartzman WS, Gabbay J, Ghazalpour A, Bennett BJ, Allayee H.

Curr Atheroscler Rep. 2017 Feb;19(2):6. doi: 10.1007/s11883-017-0641-6. Review.

3.

Multi-platform molecular profiling of a large cohort of glioblastomas reveals potential therapeutic strategies.

Xiu J, Piccioni D, Juarez T, Pingle SC, Hu J, Rudnick J, Fink K, Spetzler DB, Maney T, Ghazalpour A, Bender R, Gatalica Z, Reddy S, Sanai N, Idbaih A, Glantz M, Kesari S.

Oncotarget. 2016 Apr 19;7(16):21556-69. doi: 10.18632/oncotarget.7722.

4.

Expanding role of gut microbiota in lipid metabolism.

Ghazalpour A, Cespedes I, Bennett BJ, Allayee H.

Curr Opin Lipidol. 2016 Apr;27(2):141-7. doi: 10.1097/MOL.0000000000000278. Review.

5.

Multiplatform molecular profiling identifies potentially targetable biomarkers in malignant phyllodes tumors of the breast.

Gatalica Z, Vranic S, Ghazalpour A, Xiu J, Ocal IT, McGill J, Bender RP, Discianno E, Schlum A, Sanati S, Palazzo J, Reddy S, Pockaj B.

Oncotarget. 2016 Jan 12;7(2):1707-16. doi: 10.18632/oncotarget.6421.

6.

Mutations in the Kinase Domain of the HER2/ERBB2 Gene Identified in a Wide Variety of Human Cancers.

Wen W, Chen WS, Xiao N, Bender R, Ghazalpour A, Tan Z, Swensen J, Millis SZ, Basu G, Gatalica Z, Press MF.

J Mol Diagn. 2015 Sep;17(5):487-95. doi: 10.1016/j.jmoldx.2015.04.003.

7.

The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice.

Zhou X, Crow AL, Hartiala J, Spindler TJ, Ghazalpour A, Barsky LW, Bennett BJ, Parks BW, Eskin E, Jain R, Epstein JA, Lusis AJ, Adams GB, Allayee H.

Stem Cell Reports. 2015 Jul 14;5(1):125-38. doi: 10.1016/j.stemcr.2015.05.008. Epub 2015 Jun 4.

8.

Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice.

Orozco LD, Morselli M, Rubbi L, Guo W, Go J, Shi H, Lopez D, Furlotte NA, Bennett BJ, Farber CR, Ghazalpour A, Zhang MQ, Bahous R, Rozen R, Lusis AJ, Pellegrini M.

Cell Metab. 2015 Jun 2;21(6):905-17. doi: 10.1016/j.cmet.2015.04.025.

9.

Programmed cell death 1 (PD-1) and its ligand (PD-L1) in common cancers and their correlation with molecular cancer type.

Gatalica Z, Snyder C, Maney T, Ghazalpour A, Holterman DA, Xiao N, Overberg P, Rose I, Basu GD, Vranic S, Lynch HT, Von Hoff DD, Hamid O.

Cancer Epidemiol Biomarkers Prev. 2014 Dec;23(12):2965-70. doi: 10.1158/1055-9965.EPI-14-0654. Epub 2014 Nov 12.

10.

Oncocytoma-like renal tumor with transformation toward high-grade oncocytic carcinoma: a unique case with morphologic, immunohistochemical, and genomic characterization.

Sirintrapun SJ, Geisinger KR, Cimic A, Snow A, Hagenkord J, Monzon F, Legendre BL Jr, Ghazalpour A, Bender RP, Gatalica Z.

Medicine (Baltimore). 2014 Oct;93(15):e81. doi: 10.1097/MD.0000000000000081.

11.

Genetic regulation of mouse liver metabolite levels.

Ghazalpour A, Bennett BJ, Shih D, Che N, Orozco L, Pan C, Hagopian R, He A, Kayne P, Yang WP, Kirchgessner T, Lusis AJ.

Mol Syst Biol. 2014 May 23;10:730. doi: 10.15252/msb.20135004.

12.

Extraskeletal myxoid chondrosarcoma of the vulva with PLAG1 gene activation: molecular genetic characterization of 2 cases.

Dotlic S, Gatalica Z, Wen W, Ghazalpour A, Mangham C, Babic D, Zekan J, Vranic S.

Appl Immunohistochem Mol Morphol. 2014 Aug;22(7):537-42. doi: 10.1097/PAI.0b013e31829852e7.

PMID:
24185117
13.

Analysis of allele-specific expression in mouse liver by RNA-Seq: a comparison with Cis-eQTL identified using genetic linkage.

Lagarrigue S, Martin L, Hormozdiari F, Roux PF, Pan C, van Nas A, Demeure O, Cantor R, Ghazalpour A, Eskin E, Lusis AJ.

Genetics. 2013 Nov;195(3):1157-66. doi: 10.1534/genetics.113.153882. Epub 2013 Sep 11. Erratum in: Genetics. 2014 Apr;196(4):1359.

14.

The systems genetics resource: a web application to mine global data for complex disease traits.

van Nas A, Pan C, Ingram-Drake LA, Ghazalpour A, Drake TA, Sobel EM, Papp JC, Lusis AJ.

Front Genet. 2013 May 20;4:84. doi: 10.3389/fgene.2013.00084. eCollection 2013.

15.

Limited RNA editing in exons of mouse liver and adipose.

Lagarrigue S, Hormozdiari F, Martin LJ, Lecerf F, Hasin Y, Rau C, Hagopian R, Xiao Y, Yan J, Drake TA, Ghazalpour A, Eskin E, Lusis AJ.

Genetics. 2013 Apr;193(4):1107-15. doi: 10.1534/genetics.112.149054. Epub 2013 Feb 14.

16.

Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages.

Orozco LD, Bennett BJ, Farber CR, Ghazalpour A, Pan C, Che N, Wen P, Qi HX, Mutukulu A, Siemers N, Neuhaus I, Yordanova R, Gargalovic P, Pellegrini M, Kirchgessner T, Lusis AJ.

Cell. 2012 Oct 26;151(3):658-70. doi: 10.1016/j.cell.2012.08.043.

17.

Juxtaglomerular cell tumor: a morphological, immunohistochemical and genetic study of six cases.

Kuroda N, Maris S, Monzon FA, Tan PH, Thomas A, Petersson FB, Gatalica Z, Ghazalpour A, Bender RP, Grossmann P, Michal M, Svajdler M, Ovcak Z, Hora M, Hes O.

Hum Pathol. 2013 Jan;44(1):47-54. doi: 10.1016/j.humpath.2012.04.006. Epub 2012 Aug 29.

PMID:
22939575
18.

Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits.

Ghazalpour A, Rau CD, Farber CR, Bennett BJ, Orozco LD, van Nas A, Pan C, Allayee H, Beaven SW, Civelek M, Davis RC, Drake TA, Friedman RA, Furlotte N, Hui ST, Jentsch JD, Kostem E, Kang HM, Kang EY, Joo JW, Korshunov VA, Laughlin RE, Martin LJ, Ohmen JD, Parks BW, Pellegrini M, Reue K, Smith DJ, Tetradis S, Wang J, Wang Y, Weiss JN, Kirchgessner T, Gargalovic PS, Eskin E, Lusis AJ, LeBoeuf RC.

Mamm Genome. 2012 Oct;23(9-10):680-92. doi: 10.1007/s00335-012-9411-5. Epub 2012 Aug 15. Review.

19.

Genetic locus on mouse chromosome 7 controls elevated heart rate.

Smolock EM, Ilyushkina IA, Ghazalpour A, Gerloff J, Murashev AN, Lusis AJ, Korshunov VA.

Physiol Genomics. 2012 Jul 3;44(13):689-98. doi: 10.1152/physiolgenomics.00041.2012. Epub 2012 May 15.

20.

Quantitative trait Loci association mapping by imputation of strain origins in multifounder crosses.

Zhou JJ, Ghazalpour A, Sobel EM, Sinsheimer JS, Lange K.

Genetics. 2012 Feb;190(2):459-73. doi: 10.1534/genetics.111.135095. Epub 2011 Dec 5.

21.

Comparative analysis of proteome and transcriptome variation in mouse.

Ghazalpour A, Bennett B, Petyuk VA, Orozco L, Hagopian R, Mungrue IN, Farber CR, Sinsheimer J, Kang HM, Furlotte N, Park CC, Wen PZ, Brewer H, Weitz K, Camp DG 2nd, Pan C, Yordanova R, Neuhaus I, Tilford C, Siemers N, Gargalovic P, Eskin E, Kirchgessner T, Smith DJ, Smith RD, Lusis AJ.

PLoS Genet. 2011 Jun;7(6):e1001393. doi: 10.1371/journal.pgen.1001393. Epub 2011 Jun 9.

22.

Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis.

Farber CR, Bennett BJ, Orozco L, Zou W, Lira A, Kostem E, Kang HM, Furlotte N, Berberyan A, Ghazalpour A, Suwanwela J, Drake TA, Eskin E, Wang QT, Teitelbaum SL, Lusis AJ.

PLoS Genet. 2011 Apr;7(4):e1002038. doi: 10.1371/journal.pgen.1002038. Epub 2011 Apr 7.

23.

Gene networks associated with conditional fear in mice identified using a systems genetics approach.

Park CC, Gale GD, de Jong S, Ghazalpour A, Bennett BJ, Farber CR, Langfelder P, Lin A, Khan AH, Eskin E, Horvath S, Lusis AJ, Ophoff RA, Smith DJ.

BMC Syst Biol. 2011 Mar 16;5:43. doi: 10.1186/1752-0509-5-43.

24.

A high-resolution association mapping panel for the dissection of complex traits in mice.

Bennett BJ, Farber CR, Orozco L, Kang HM, Ghazalpour A, Siemers N, Neubauer M, Neuhaus I, Yordanova R, Guan B, Truong A, Yang WP, He A, Kayne P, Gargalovic P, Kirchgessner T, Pan C, Castellani LW, Kostem E, Furlotte N, Drake TA, Eskin E, Lusis AJ.

Genome Res. 2010 Feb;20(2):281-90. doi: 10.1101/gr.099234.109. Epub 2010 Jan 6.

25.

Copy number variation influences gene expression and metabolic traits in mice.

Orozco LD, Cokus SJ, Ghazalpour A, Ingram-Drake L, Wang S, van Nas A, Che N, Araujo JA, Pellegrini M, Lusis AJ.

Hum Mol Genet. 2009 Nov 1;18(21):4118-29. doi: 10.1093/hmg/ddp360. Epub 2009 Jul 31.

26.

Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks.

Yang X, Deignan JL, Qi H, Zhu J, Qian S, Zhong J, Torosyan G, Majid S, Falkard B, Kleinhanz RR, Karlsson J, Castellani LW, Mumick S, Wang K, Xie T, Coon M, Zhang C, Estrada-Smith D, Farber CR, Wang SS, van Nas A, Ghazalpour A, Zhang B, Macneil DJ, Lamb JR, Dipple KM, Reitman ML, Mehrabian M, Lum PY, Schadt EE, Lusis AJ, Drake TA.

Nat Genet. 2009 Apr;41(4):415-23. doi: 10.1038/ng.325. Epub 2009 Mar 8.

27.

An integrative genetics approach to identify candidate genes regulating BMD: combining linkage, gene expression, and association.

Farber CR, van Nas A, Ghazalpour A, Aten JE, Doss S, Sos B, Schadt EE, Ingram-Drake L, Davis RC, Horvath S, Smith DJ, Drake TA, Lusis AJ.

J Bone Miner Res. 2009 Jan;24(1):105-16. doi: 10.1359/jbmr.080908.

28.

High-resolution mapping of gene expression using association in an outbred mouse stock.

Ghazalpour A, Doss S, Kang H, Farber C, Wen PZ, Brozell A, Castellanos R, Eskin E, Smith DJ, Drake TA, Lusis AJ.

PLoS Genet. 2008 Aug 8;4(8):e1000149. doi: 10.1371/journal.pgen.1000149.

29.

Variations in DNA elucidate molecular networks that cause disease.

Chen Y, Zhu J, Lum PY, Yang X, Pinto S, MacNeil DJ, Zhang C, Lamb J, Edwards S, Sieberts SK, Leonardson A, Castellini LW, Wang S, Champy MF, Zhang B, Emilsson V, Doss S, Ghazalpour A, Horvath S, Drake TA, Lusis AJ, Schadt EE.

Nature. 2008 Mar 27;452(7186):429-35. doi: 10.1038/nature06757. Epub 2008 Mar 16.

30.

Weighted gene coexpression network analysis strategies applied to mouse weight.

Fuller TF, Ghazalpour A, Aten JE, Drake TA, Lusis AJ, Horvath S.

Mamm Genome. 2007 Jul;18(6-7):463-72. Epub 2007 Aug 1.

31.

Integrating genetic and network analysis to characterize genes related to mouse weight.

Ghazalpour A, Doss S, Zhang B, Wang S, Plaisier C, Castellanos R, Brozell A, Schadt EE, Drake TA, Lusis AJ, Horvath S.

PLoS Genet. 2006 Aug 18;2(8):e130. Epub 2006 Jul 5.

32.

Complex inheritance of the 5-lipoxygenase locus influencing atherosclerosis in mice.

Ghazalpour A, Wang X, Lusis AJ, Mehrabian M.

Genetics. 2006 Jun;173(2):943-51. Epub 2006 Apr 19.

33.

Hepatocellular carcinoma in Txnip-deficient mice.

Sheth SS, Bodnar JS, Ghazalpour A, Thipphavong CK, Tsutsumi S, Tward AD, Demant P, Kodama T, Aburatani H, Lusis AJ.

Oncogene. 2006 Jun 15;25(25):3528-36. Epub 2006 Apr 10.

PMID:
16607285
34.

Genomic analysis of metabolic pathway gene expression in mice.

Ghazalpour A, Doss S, Sheth SS, Ingram-Drake LA, Schadt EE, Lusis AJ, Drake TA.

Genome Biol. 2005;6(7):R59. Epub 2005 Jul 1.

35.

Thematic review series: The pathogenesis of atherosclerosis. Toward a biological network for atherosclerosis.

Ghazalpour A, Doss S, Yang X, Aten J, Toomey EM, Van Nas A, Wang S, Drake TA, Lusis AJ.

J Lipid Res. 2004 Oct;45(10):1793-805. Epub 2004 Aug 1. Review.

36.

Using mice to dissect genetic factors in atherosclerosis.

Allayee H, Ghazalpour A, Lusis AJ.

Arterioscler Thromb Vasc Biol. 2003 Sep 1;23(9):1501-9. Epub 2003 Aug 14. Review.

PMID:
12920046
37.

Genetic loci contributing to age-related hippocampal lesions in mice.

Krass KL, Colinayo V, Ghazalpour A, Vinters HV, Lusis AJ, Drake TA.

Neurobiol Dis. 2003 Jul;13(2):102-8.

PMID:
12828934

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