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Items: 1 to 50 of 219

1.

Metabolic Regulators Nampt and Sirt6 Serially Participate in the Macrophage Interferon Antiviral Cascade.

Dantoft W, Robertson KA, Watkins WJ, Strobl B, Ghazal P.

Front Microbiol. 2019 Mar 4;10:355. doi: 10.3389/fmicb.2019.00355. eCollection 2019.

2.

The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells.

Perucha E, Melchiotti R, Bibby JA, Wu W, Frederiksen KS, Roberts CA, Hall Z, LeFriec G, Robertson KA, Lavender P, Gerwien JG, Taams LS, Griffin JL, de Rinaldis E, van Baarsen LGM, Kemper C, Ghazal P, Cope AP.

Nat Commun. 2019 Jan 30;10(1):498. doi: 10.1038/s41467-019-08332-9.

3.

Rising trend of substance abuse in Pakistan: a study of sociodemographic profiles of patients admitted to rehabilitation centres.

Ghazal P.

Public Health. 2019 Feb;167:34-37. doi: 10.1016/j.puhe.2018.10.020. Epub 2019 Jan 4.

PMID:
30616031
4.

Meta-Analysis Identification of Highly Robust and Differential Immune-Metabolic Signatures of Systemic Host Response to Acute and Latent Tuberculosis in Children and Adults.

Bah SY, Forster T, Dickinson P, Kampmann B, Ghazal P.

Front Genet. 2018 Oct 4;9:457. doi: 10.3389/fgene.2018.00457. eCollection 2018.

5.

Pulmonary epithelial barrier and immunological functions at birth and in early life - key determinants of the development of asthma?  A description of the protocol for the Breathing Together study.

Turner S, Custovic A, Ghazal P, Grigg J, Gore M, Henderson J, Lloyd CM, Marsland B, Power UF, Roberts G, Saglani S, Schwarze J, Shields M, Bush A.

Wellcome Open Res. 2018 May 17;3:60. doi: 10.12688/wellcomeopenres.14489.1. eCollection 2018.

6.

Purine metabolism controls innate lymphoid cell function and protects against intestinal injury.

Crittenden S, Cheyne A, Adams A, Forster T, Robb CT, Felton J, Ho GT, Ruckerl D, Rossi AG, Anderton SM, Ghazal P, Satsangi J, Howie SE, Yao C.

Immunol Cell Biol. 2018 Nov;96(10):1049-1059. doi: 10.1111/imcb.12167. Epub 2018 Jul 10.

7.

Lipomatosen.

Al Ghazal P, Grönemeyer LL, Schön MP.

J Dtsch Dermatol Ges. 2018 Mar;16(3):313-328. doi: 10.1111/ddg.13460_g.

PMID:
29537156
8.

Lipomatoses.

Al Ghazal P, Grönemeyer LL, Schön MP.

J Dtsch Dermatol Ges. 2018 Mar;16(3):313-327. doi: 10.1111/ddg.13460. Epub 2018 Feb 12. Review.

PMID:
29431910
9.

The neonatal window of opportunity-early priming for life.

Renz H, Adkins BD, Bartfeld S, Blumberg RS, Farber DL, Garssen J, Ghazal P, Hackam DJ, Marsland BJ, McCoy KD, Penders J, Prinz I, Verhasselt V, von Mutius E, Weiser JN, Wesemann DR, Hornef MW.

J Allergy Clin Immunol. 2018 Apr;141(4):1212-1214. doi: 10.1016/j.jaci.2017.11.019. Epub 2017 Dec 14. No abstract available.

10.

Genomic Programming of Human Neonatal Dendritic Cells in Congenital Systemic and In Vitro Cytomegalovirus Infection Reveal Plastic and Robust Immune Pathway Biology Responses.

Dantoft W, Martínez-Vicente P, Jafali J, Pérez-Martínez L, Martin K, Kotzamanis K, Craigon M, Auer M, Young NT, Walsh P, Marchant A, Angulo A, Forster T, Ghazal P.

Front Immunol. 2017 Sep 25;8:1146. doi: 10.3389/fimmu.2017.01146. eCollection 2017.

11.

Is systems pharmacology ready to impact upon therapy development? A study on the cholesterol biosynthesis pathway.

Benson HE, Watterson S, Sharman JL, Mpamhanga CP, Parton A, Southan C, Harmar AJ, Ghazal P.

Br J Pharmacol. 2017 Dec;174(23):4362-4382. doi: 10.1111/bph.14037. Epub 2017 Nov 26.

12.

Evolutionary Origin of the Interferon-Immune Metabolic Axis: The Sterol-Vitamin D Link.

Newmark H, Dantoft W, Ghazal P.

Front Immunol. 2017 Feb 9;8:62. doi: 10.3389/fimmu.2017.00062. eCollection 2017.

13.

Interferon Control of the Sterol Metabolic Network: Bidirectional Molecular Circuitry-Mediating Host Protection.

Robertson KA, Ghazal P.

Front Immunol. 2016 Dec 23;7:634. doi: 10.3389/fimmu.2016.00634. eCollection 2016. Review.

14.

The volume of postoperative drainage fluid as a potential early predictor of lymphedema after lymph node excision for metastatic melanoma.

Kretschmer L, Hellriegel S, Thoms KM, Schon MP, Al Ghazal P, Zapf A.

Lymphology. 2017;50(3):120-130.

PMID:
30234248
15.

Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence.

Clement M, Marsden M, Stacey MA, Abdul-Karim J, Gimeno Brias S, Costa Bento D, Scurr MJ, Ghazal P, Weaver CT, Carlesso G, Clare S, Jones SA, Godkin A, Jones GW, Humphreys IR.

PLoS Pathog. 2016 Dec 7;12(12):e1006050. doi: 10.1371/journal.ppat.1006050. eCollection 2016 Dec.

16.

Tricenter analysis of cofactors and comorbidity in patients with pyoderma gangrenosum.

Jockenhöfer F, Herberger K, Schaller J, Hohaus KC, Stoffels-Weindorf M, Ghazal PA, Augustin M, Dissemond J.

J Dtsch Dermatol Ges. 2016 Oct;14(10):1023-1030. doi: 10.1111/ddg.12791.

PMID:
27767288
17.

Trizentrische Analyse von Kofaktoren und Komorbidität des Pyoderma gangraenosum.

Jockenhöfer F, Herberger K, Schaller J, Hohaus KC, Stoffels-Weindorf M, Ghazal PA, Augustin M, Dissemond J.

J Dtsch Dermatol Ges. 2016 Oct;14(10):1023-1031. doi: 10.1111/ddg.12791_g.

PMID:
27767262
18.

AMPA receptor trafficking in recent vs. remote memory.

Ghazal P.

Brain Res. 2016 Nov 1;1650:203-207. doi: 10.1016/j.brainres.2016.09.010. Epub 2016 Sep 8.

PMID:
27614139
19.

Percutaneous ultrasound-guided drainage of needle aspiration-refractory seromas following lymph node excision.

Baltzer A, Brehmer F, Forkel S, Al Ghazal P, Schön MP, Kretschmer L.

J Dtsch Dermatol Ges. 2016 Aug;14(8):850-2. doi: 10.1111/ddg.13090. No abstract available.

PMID:
27509434
20.

Perkutane Ultraschall-gesteuerte Durchstichdrainage therapierefraktärer Serome nach Lymphknotenexzision.

Baltzer A, Brehmer F, Forkel S, Ghazal PA, Schön MP, Kretschmer L.

J Dtsch Dermatol Ges. 2016 Aug;14(8):850-2. doi: 10.1111/ddg.13090_g. No abstract available.

PMID:
27509433
21.

Sex-Differential Non-Vaccine-Specific Immunological Effects of Diphtheria-Tetanus-Pertussis and Measles Vaccination.

Noho-Konteh F, Adetifa JU, Cox M, Hossin S, Reynolds J, Le MT, Sanyang LC, Drammeh A, Plebanski M, Forster T, Dickinson P, Ghazal P, Whittle H, Rowland-Jones SL, Sutherland JS, Flanagan KL.

Clin Infect Dis. 2016 Nov 1;63(9):1213-1226. Epub 2016 Jul 19.

22.

Immune oxysterols: Role in mycobacterial infection and inflammation.

Bah SY, Dickinson P, Forster T, Kampmann B, Ghazal P.

J Steroid Biochem Mol Biol. 2017 May;169:152-163. doi: 10.1016/j.jsbmb.2016.04.015. Epub 2016 May 4. Review.

23.

Prostaglandin E₂ constrains systemic inflammation through an innate lymphoid cell-IL-22 axis.

Duffin R, O'Connor RA, Crittenden S, Forster T, Yu C, Zheng X, Smyth D, Robb CT, Rossi F, Skouras C, Tang S, Richards J, Pellicoro A, Weller RB, Breyer RM, Mole DJ, Iredale JP, Anderton SM, Narumiya S, Maizels RM, Ghazal P, Howie SE, Rossi AG, Yao C.

Science. 2016 Mar 18;351(6279):1333-8. doi: 10.1126/science.aad9903.

24.

An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway.

Robertson KA, Hsieh WY, Forster T, Blanc M, Lu H, Crick PJ, Yutuc E, Watterson S, Martin K, Griffiths SJ, Enright AJ, Yamamoto M, Pradeepa MM, Lennox KA, Behlke MA, Talbot S, Haas J, Dölken L, Griffiths WJ, Wang Y, Angulo A, Ghazal P.

PLoS Biol. 2016 Mar 3;14(3):e1002364. doi: 10.1371/journal.pbio.1002364. eCollection 2016 Mar.

25.
26.

Updated results of 100 patients on clinical features and therapeutic options in necrobiosis lipoidica in a retrospective multicentre study.

Erfurt-Berge C, Dissemond J, Schwede K, Seitz AT, Al Ghazal P, Wollina U, Renner R.

Eur J Dermatol. 2015 Nov-Dec;25(6):595-601. doi: 10.1684/ejd.2015.2636.

PMID:
26575980
27.

Whole blood gene expression profiling of neonates with confirmed bacterial sepsis.

Dickinson P, Smith CL, Forster T, Craigon M, Ross AJ, Khondoker MR, Ivens A, Lynn DJ, Orme J, Jackson A, Lacaze P, Flanagan KL, Stenson BJ, Ghazal P.

Genom Data. 2014 Nov 15;3:41-8. doi: 10.1016/j.gdata.2014.11.003. eCollection 2015 Mar.

28.

Patients with pyoderma gangrenosum - analyses of the German DRG data from 2012.

Jockenhöfer F, Klode J, Kröger K, Roesch A, Al Ghazal P, Dissemond J.

Int Wound J. 2016 Oct;13(5):951-6. doi: 10.1111/iwj.12463. Epub 2015 Aug 6.

PMID:
26250591
29.

Draft Genome Sequences of Six Different Staphylococcus epidermidis Clones, Isolated Individually from Preterm Neonates Presenting with Sepsis at Edinburgh's Royal Infirmary.

Walsh P, Bekaert M, Carroll J, Manning T, Kelly B, O'Driscoll A, Lu X, Smith C, Dickinson P, Templeton K, Ghazal P, Sleator RD.

Genome Announc. 2015 May 14;3(3). pii: e00471-15. doi: 10.1128/genomeA.00471-15.

30.

A temporal gate for viral enhancers to co-opt Toll-like-receptor transcriptional activation pathways upon acute infection.

Kropp KA, Hsieh WY, Isern E, Forster T, Krause E, Brune W, Angulo A, Ghazal P.

PLoS Pathog. 2015 Apr 9;11(4):e1004737. doi: 10.1371/journal.ppat.1004737. eCollection 2015 Apr.

31.

Infection homeostasis: implications for therapeutic and immune programming of metabolism in controlling infection.

Kotzamanis K, Angulo A, Ghazal P.

Med Microbiol Immunol. 2015 Jun;204(3):395-407. doi: 10.1007/s00430-015-0402-5. Epub 2015 Mar 24. Review.

32.

Therapy of pyoderma gangrenosum in Germany: results of a survey among wound experts.

Al Ghazal P, Dissemond J.

J Dtsch Dermatol Ges. 2015 Apr;13(4):317-24. doi: 10.1111/ddg.12585. Epub 2015 Mar 11.

PMID:
25761564
33.

Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis.

Lu H, Talbot S, Robertson KA, Watterson S, Forster T, Roy D, Ghazal P.

Steroids. 2015 Jul;99(Pt B):219-29. doi: 10.1016/j.steroids.2015.02.022. Epub 2015 Mar 7.

34.

CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue.

Stack G, Jones E, Marsden M, Stacey MA, Snelgrove RJ, Lacaze P, Jacques LC, Cuff SM, Stanton RJ, Gallimore AM, Hussell T, Wilkinson GW, Ghazal P, Taylor PR, Humphreys IR.

PLoS Pathog. 2015 Feb 5;11(2):e1004641. doi: 10.1371/journal.ppat.1004641. eCollection 2015 Feb.

35.

HBLAST: Parallelised sequence similarity--A Hadoop MapReducable basic local alignment search tool.

O'Driscoll A, Belogrudov V, Carroll J, Kropp K, Walsh P, Ghazal P, Sleator RD.

J Biomed Inform. 2015 Apr;54:58-64. doi: 10.1016/j.jbi.2015.01.008. Epub 2015 Jan 24.

36.

Diagnostic criteria for pyoderma gangrenosum: results of a survey among dermatologic wound experts in Germany.

Al Ghazal P, Klode J, Dissemond J.

J Dtsch Dermatol Ges. 2014 Dec 5. doi: 10.1111/ddg.14570. [Epub ahead of print] No abstract available.

PMID:
25482862
37.

Diagnostic criteria for pyoderma gangrenosum: results of a survey among dermatologic wound experts in Germany.

Al Ghazal P, Klode J, Dissemond J.

J Dtsch Dermatol Ges. 2014 Dec;12(12):1129-31. doi: 10.1111/ddg.12401. English, German. No abstract available.

PMID:
25482699
38.

Paradoxical response to the sedative effects of diazepam and alcohol in C57BL/6J mice lacking the neuropeptide S receptor.

Ghazal P, Corsi M, Roth A, Faggioni F, Corti C, Merlo Pick E, Pucciarelli S, Ciccocioppo R, Ubaldi M.

Peptides. 2014 Nov;61:107-13. doi: 10.1016/j.peptides.2014.09.010. Epub 2014 Sep 18.

PMID:
25240770
39.

Draft Genome Sequence of a Serratia marcescens Strain Isolated from a Preterm Neonatal Blood Sepsis Patient at the Royal Infirmary, Edinburgh, Scotland, United Kingdom.

Kropp KA, Lucid A, Carroll J, Belgrudov V, Walsh P, Kelly B, Smith C, Dickinson P, O'Driscoll A, Templeton K, Ghazal P, Sleator RD.

Genome Announc. 2014 Sep 11;2(5). pii: e00908-14. doi: 10.1128/genomeA.00908-14.

40.

Draft Genome Sequence of an Enterococcus faecalis Strain Isolated from a Neonatal Blood Sepsis Patient.

Kropp KA, Lucid A, Carroll J, Belgrudov V, Walsh P, Kelly B, Smith C, Dickinson P, O'Driscoll A, Templeton K, Ghazal P, Sleator RD.

Genome Announc. 2014 Sep 11;2(5). pii: e00907-14. doi: 10.1128/genomeA.00907-14.

41.

Draft Genome Sequence of a Staphylococcus aureus Isolate Taken from the Blood of a Preterm Neonatal Blood Sepsis Patient.

Kropp KA, Lucid A, Carroll J, Belgrudov V, Walsh P, Kelly B, Templeton K, Smith C, Dickinson P, O'Driscoll A, Ghazal P, Sleator RD.

Genome Announc. 2014 Sep 11;2(5). pii: e00906-14. doi: 10.1128/genomeA.00906-14.

42.

Draft Genome Sequence of a Pantoea sp. Isolated from a Preterm Neonatal Blood Sepsis Patient.

Kropp KA, Lucid A, Carroll J, Belgrudov V, Walsh P, Kelly B, Templeton K, Smith C, Dickinson P, O'Driscoll A, Ghazal P, Sleator RD.

Genome Announc. 2014 Sep 11;2(5). pii: e00904-14. doi: 10.1128/genomeA.00904-14.

43.

Draft Genome Sequence of a Staphylococcus warneri Strain Isolated from a Preterm Neonate Blood Sepsis Patient at the Royal Infirmary, Edinburgh, Scotland.

Kropp KA, Lucid A, Carroll J, Belgrudov V, Walsh P, Kelly B, Smith C, Dickinson P, O'Driscoll A, Templeton K, Ghazal P, Sleator RD.

Genome Announc. 2014 Sep 4;2(5). pii: e00877-14. doi: 10.1128/genomeA.00877-14.

44.

Draft Genome Sequence of a Streptococcus agalactiae Strain Isolated from a Preterm Neonate Blood Sepsis Patient at the Royal Infirmary, Edinburgh, Scotland.

Kropp KA, Lucid A, Carroll J, Belgrudov V, Walsh P, Kelly B, Smith C, Dickinson P, O'Driscoll A, Templeton K, Ghazal P, Sleator RD.

Genome Announc. 2014 Sep 4;2(5). pii: e00875-14. doi: 10.1128/genomeA.00875-14.

45.

Identification of a human neonatal immune-metabolic network associated with bacterial infection.

Smith CL, Dickinson P, Forster T, Craigon M, Ross A, Khondoker MR, France R, Ivens A, Lynn DJ, Orme J, Jackson A, Lacaze P, Flanagan KL, Stenson BJ, Ghazal P.

Nat Commun. 2014 Aug 14;5:4649. doi: 10.1038/ncomms5649.

46.

A loss of function analysis of host factors influencing Vaccinia virus replication by RNA interference.

Beard PM, Griffiths SJ, Gonzalez O, Haga IR, Pechenick Jowers T, Reynolds DK, Wildenhain J, Tekotte H, Auer M, Tyers M, Ghazal P, Zimmer R, Haas J.

PLoS One. 2014 Jun 5;9(6):e98431. doi: 10.1371/journal.pone.0098431. eCollection 2014.

47.

Parallel classification and feature selection in microarray data using SPRINT.

Mitchell L, Sloan TM, Mewissen M, Ghazal P, Forster T, Piotrowski M, Trew A.

Concurr Comput. 2014 Mar 25;26(4):854-865.

48.

Viral enhancer mimicry of host innate-immune promoters.

Kropp KA, Angulo A, Ghazal P.

PLoS Pathog. 2014 Feb 6;10(2):e1003804. doi: 10.1371/journal.ppat.1003804. eCollection 2014 Feb. Review. No abstract available.

49.

Differential influence of vemurafenib and dabrafenib on patients' lymphocytes despite similar clinical efficacy in melanoma.

Schilling B, Sondermann W, Zhao F, Griewank KG, Livingstone E, Sucker A, Zelba H, Weide B, Trefzer U, Wilhelm T, Loquai C, Berking C, Hassel J, Kähler KC, Utikal J, Al Ghazal P, Gutzmer R, Goldinger SM, Zimmer L, Paschen A, Hillen U, Schadendorf D; DeCOG.

Ann Oncol. 2014 Mar;25(3):747-53. doi: 10.1093/annonc/mdt587. Epub 2014 Feb 6.

50.

Lower prevalence of lymphatic metastasis and poorer survival of the sentinel node-negative patients limit the prognostic value of sentinel node biopsy for head or neck melanomas.

Al Ghazal P, Gutzmer R, Satzger I, Starz H, Bader C, Thoms KM, Mitteldorf C, Schön MP, Kapp A, Bertsch HP, Kretschmer L.

Melanoma Res. 2014 Apr;24(2):158-64. doi: 10.1097/CMR.0000000000000042.

PMID:
24346168

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