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Items: 16


Gain of the short arm of chromosome 2 (2p gain) has a significant role in drug-resistant chronic lymphocytic leukemia.

Kostopoulou F, Gabillaud C, Chapiro E, Grange B, Tran J, Bouzy S, Degaud M, Ghamlouch H, Le Garff-Tavernier M, Maloum K, Choquet S, Leblond V, Gabarre J, Lavaud A, Morel V, Roos-Weil D, Uzunov M, Guieze R, Bernard OA, Susin SA, Tournilhac O, Nguyen-Khac F; French Innovative Leukemia Organization (FILO) group.

Cancer Med. 2019 May 7. doi: 10.1002/cam4.2123. [Epub ahead of print]


A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation.

Roos-Weil D, Decaudin C, Armand M, Della-Valle V, Diop MK, Ghamlouch H, Ropars V, Hérate C, Lara D, Durot E, Haddad R, Mylonas E, Damm F, Pflumio F, Stoilova B, Metzner M, Elemento O, Dessen P, Camara-Clayette V, Cosset FL, Verhoeyen E, Leblond V, Ribrag V, Cornillet-Lefebvre P, Rameau P, Azar N, Charlotte F, Morel P, Charbonnier JB, Vyas P, Mercher T, Aoufouchi S, Droin N, Guillouf C, Nguyen-Khac F, Bernard OA.

Cancer Discov. 2019 Apr 24. doi: 10.1158/2159-8290.CD-18-0873. [Epub ahead of print]


A miR-150/TET3 pathway regulates the generation of mouse and human non-classical monocyte subset.

Selimoglu-Buet D, Rivière J, Ghamlouch H, Bencheikh L, Lacout C, Morabito M, Diop M, Meurice G, Breckler M, Chauveau A, Debord C, Debeurme F, Itzykson R, Chapuis N, Willekens C, Wagner-Ballon O, Bernard OA, Droin N, Solary E.

Nat Commun. 2018 Dec 21;9(1):5455. doi: 10.1038/s41467-018-07801-x.


TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis.

Dominguez PM, Ghamlouch H, Rosikiewicz W, Kumar P, Béguelin W, Fontán L, Rivas MA, Pawlikowska P, Armand M, Mouly E, Torres-Martin M, Doane AS, Calvo Fernandez MT, Durant M, Della-Valle V, Teater M, Cimmino L, Droin N, Tadros S, Motanagh S, Shih AH, Rubin MA, Tam W, Aifantis I, Levine RL, Elemento O, Inghirami G, Green MR, Figueroa ME, Bernard OA, Aoufouchi S, Li S, Shaknovich R, Melnick AM.

Cancer Discov. 2018 Dec;8(12):1632-1653. doi: 10.1158/2159-8290.CD-18-0657. Epub 2018 Oct 1.


Chronic Lymphocytic Leukemia B-Cell Normal Cellular Counterpart: Clues From a Functional Perspective.

Darwiche W, Gubler B, Marolleau JP, Ghamlouch H.

Front Immunol. 2018 Apr 4;9:683. doi: 10.3389/fimmu.2018.00683. eCollection 2018. Review.


B-cell tumor development in Tet2-deficient mice.

Mouly E, Ghamlouch H, Della-Valle V, Scourzic L, Quivoron C, Roos-Weil D, Pawlikowska P, Saada V, Diop MK, Lopez CK, Fontenay M, Dessen P, Touw IP, Mercher T, Aoufouchi S, Bernard OA.

Blood Adv. 2018 Mar 27;2(6):703-714. doi: 10.1182/bloodadvances.2017014118.


Chronic lymphocytic leukaemia genomics and the precision medicine era.

Ghamlouch H, Nguyen-Khac F, Bernard OA.

Br J Haematol. 2017 Sep;178(6):852-870. doi: 10.1111/bjh.14719. Epub 2017 Apr 25. Review.


The Importance of an In-depth Study of Immunoglobulin Gene Rearrangements When Ascertaining the Clonal Relationship between Concomitant Chronic Lymphocytic Leukemia and Multiple Myeloma.

Trudel S, Ghamlouch H, Dremaux J, Delette C, Harrivel V, Marolleau JP, Gubler B.

Front Immunol. 2016 Dec 27;7:625. doi: 10.3389/fimmu.2016.00625. eCollection 2016.


Impact of prenatal and postnatal exposure to the pesticide chlorpyrifos on the contraction of rat ileal muscle strips: involvement of an inducible nitric oxide synthase-dependent pathway.

Darwiche W, Delanaud S, Dupont S, Ghamlouch H, Ramadan W, Joumaa W, Bach V, Gay-Quéheillard J.

Neurogastroenterol Motil. 2017 Feb;29(2). doi: 10.1111/nmo.12918. Epub 2016 Aug 21.


Factors involved in CLL pathogenesis and cell survival are disrupted by differentiation of CLL B-cells into antibody-secreting cells.

Ghamlouch H, Darwiche W, Hodroge A, Ouled-Haddou H, Dupont S, Singh AR, Guignant C, Trudel S, Royer B, Gubler B, Marolleau JP.

Oncotarget. 2015 Jul 30;6(21):18484-503.


TLR9 Ligand (CpG Oligodeoxynucleotide) Induces CLL B-Cells to Differentiate into CD20(+) Antibody-Secreting Cells.

Ghamlouch H, Ouled-Haddou H, Guyart A, Regnier A, Trudel S, Claisse JF, Fuentes V, Royer B, Marolleau JP, Gubler B.

Front Immunol. 2014 Jun 16;5:292. doi: 10.3389/fimmu.2014.00292. eCollection 2014.


Phorbol myristate acetate, but not CD40L, induces the differentiation of CLL B cells into Ab-secreting cells.

Ghamlouch H, Ouled-Haddou H, Guyart A, Regnier A, Trudel S, Claisse JF, Fuentes V, Royer B, Marolleau JP, Gubler B.

Immunol Cell Biol. 2014 Aug;92(7):591-604. doi: 10.1038/icb.2014.37. Epub 2014 May 6.


Identification of SLAMF3 (CD229) as an inhibitor of hepatocellular carcinoma cell proliferation and tumour progression.

Marcq I, Nyga R, Cartier F, Amrathlal RS, Ossart C, Ouled-Haddou H, Ghamlouch H, Galmiche A, Chatelain D, Lamotte L, Debuysscher V, Fuentes V, Nguyen-Khac E, Regimbeau JM, Marolleau JP, Latour S, Bouhlal H.

PLoS One. 2013 Dec 20;8(12):e82918. doi: 10.1371/journal.pone.0082918. eCollection 2013.


Characterization of a new V gene replacement in the absence of activation-induced cytidine deaminase and its contribution to human B-cell receptor diversity.

Ouled-Haddou H, Ghamlouch H, Regnier A, Trudel S, Herent D, Lefranc MP, Marolleau JP, Gubler B.

Immunology. 2014 Feb;141(2):268-75. doi: 10.1111/imm.12192.


A combination of cytokines rescues highly purified leukemic CLL B-cells from spontaneous apoptosis in vitro.

Ghamlouch H, Ouled-Haddou H, Damaj G, Royer B, Gubler B, Marolleau JP.

PLoS One. 2013;8(3):e60370. doi: 10.1371/journal.pone.0060370. Epub 2013 Mar 26.


Observation of vortex-lattice melting in YBa2Cu3O7- delta by Seebeck-effect measurements.

Ghamlouch H, Aubin M, Gagnon R, Taillefer L.

Phys Rev B Condens Matter. 1996 Oct 1;54(13):9070-9073. No abstract available.


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