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Items: 49


Global analysis of methionine oxidation provides a census of folding stabilities for the human proteome.

Walker EJ, Bettinger JQ, Welle KA, Hryhorenko JR, Ghaemmaghami S.

Proc Natl Acad Sci U S A. 2019 Mar 7. pii: 201819851. doi: 10.1073/pnas.1819851116. [Epub ahead of print]


JNK modifies neuronal metabolism to promote proteostasis and longevity.

Wang L, Davis SS, Borch Jensen M, Rodriguez-Fernandez IA, Apaydin C, Juhasz G, Gibson BW, Schilling B, Ramanathan A, Ghaemmaghami S, Jasper H.

Aging Cell. 2019 Feb 27:e12849. doi: 10.1111/acel.12849. [Epub ahead of print]


Developmentally regulated H2Av buffering via dynamic sequestration to lipid droplets in Drosophila embryos.

Johnson MR, Stephenson RA, Ghaemmaghami S, Welte MA.

Elife. 2018 Jul 25;7. pii: e36021. doi: 10.7554/eLife.36021.


Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice.

Popa-Wagner A, Sandu RE, Cristin C, Uzoni A, Welle KA, Hryhorenko JR, Ghaemmaghami S.

Front Aging Neurosci. 2018 Feb 16;10:32. doi: 10.3389/fnagi.2018.00032. eCollection 2018.


Outcome after Surgical Management of Acetabular Fractures: A 7-Year Experience.

Mesbahi SAR, Ghaemmaghami A, Ghaemmaghami S, Farhadi P.

Bull Emerg Trauma. 2018 Jan;6(1):37-44. doi: 10.29252/beat-060106.


Cross-species Comparison of Proteome Turnover Kinetics.

Swovick K, Welle KA, Hryhorenko JR, Seluanov A, Gorbunova V, Ghaemmaghami S.

Mol Cell Proteomics. 2018 Apr;17(4):580-591. doi: 10.1074/mcp.RA117.000574. Epub 2018 Jan 10.


Proteome-wide modulation of degradation dynamics in response to growth arrest.

Zhang T, Wolfe C, Pierle A, Welle KA, Hryhorenko JR, Ghaemmaghami S.

Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):E10329-E10338. doi: 10.1073/pnas.1710238114. Epub 2017 Nov 13.


Potential mechanisms linking SIRT activity and hypoxic 2-hydroxyglutarate generation: no role for direct enzyme (de)acetylation.

Nadtochiy SM, Wang YT, Zhang J, Nehrke K, Schafer X, Welle K, Ghaemmaghami S, Munger J, Brookes PS.

Biochem J. 2017 Aug 10;474(16):2829-2839. doi: 10.1042/BCJ20170389.


Biology and Genetics of PrP Prion Strains.

Ghaemmaghami S.

Cold Spring Harb Perspect Med. 2017 Aug 1;7(8). pii: a026922. doi: 10.1101/cshperspect.a026922. Review.


Time-resolved Analysis of Proteome Dynamics by Tandem Mass Tags and Stable Isotope Labeling in Cell Culture (TMT-SILAC) Hyperplexing.

Welle KA, Zhang T, Hryhorenko JR, Shen S, Qu J, Ghaemmaghami S.

Mol Cell Proteomics. 2016 Dec;15(12):3551-3563. Epub 2016 Oct 20.


Effect of different brewing times on antioxidant activity and polyphenol content of loosely packed and bagged black teas (Camellia sinensis L.).

Nikniaz Z, Mahdavi R, Ghaemmaghami SJ, Lotfi Yagin N, Nikniaz L.

Avicenna J Phytomed. 2016 May-Jun;6(3):313-21.


Global analysis of cellular protein flux quantifies the selectivity of basal autophagy.

Zhang T, Ghaemmaghami S.

Autophagy. 2016 Aug 2;12(8):1411-2. doi: 10.1080/15548627.2016.1190891. Epub 2016 Jun 1.


Study on mycoflora of poultry feed ingredients and finished feed in Iran.

Ghaemmaghami SS, Modirsaneii M, Khosravi AR, Razzaghi-Abyaneh M.

Iran J Microbiol. 2016 Feb;8(1):47-54.


Global Analysis of Cellular Protein Flux Quantifies the Selectivity of Basal Autophagy.

Zhang T, Shen S, Qu J, Ghaemmaghami S.

Cell Rep. 2016 Mar 15;14(10):2426-39. doi: 10.1016/j.celrep.2016.02.040. Epub 2016 Mar 3.


Visfatin effects on telomerase gene expression in AGS gastric cancer cell line.

Mohammadi M, Zarghami N, Hedayati M, Ghaemmaghami S, Yamchi RM, Mohaddes M.

Indian J Cancer. 2015 Jan-Mar;52(1):32-5. doi: 10.4103/0019-509X.175567.


Ion-Current-Based Temporal Proteomic Profiling of Influenza-A-Virus-Infected Mouse Lungs Revealed Underlying Mechanisms of Altered Integrity of the Lung Microvascular Barrier.

Shen S, Li J, Hilchey S, Shen X, Tu C, Qiu X, Ng A, Ghaemmaghami S, Wu H, Zand MS, Qu J.

J Proteome Res. 2016 Feb 5;15(2):540-53. doi: 10.1021/acs.jproteome.5b00927. Epub 2016 Jan 8.


Kinetics of precursor labeling in stable isotope labeling in cell cultures (SILAC) experiments.

Zhang T, Price JC, Nouri-Nigjeh E, Li J, Hellerstein MK, Qu J, Ghaemmaghami S.

Anal Chem. 2014 Nov 18;86(22):11334-41. doi: 10.1021/ac503067a. Epub 2014 Oct 29.


Analysis of proteome dynamics in mice by isotopic labeling.

Price JC, Ghaemmaghami S.

Methods Mol Biol. 2014;1156:111-31. doi: 10.1007/978-1-4939-0685-7_7.


Successes and challenges in phenotype-based lead discovery for prion diseases.

Ghaemmaghami S, Russo M, Renslo AR.

J Med Chem. 2014 Aug 28;57(16):6919-29. doi: 10.1021/jm5001425. Epub 2014 Apr 24. Review.


Resistin and Visfatin Expression in HCT-116 Colorectal Cancer Cell Line.

Ghaemmaghami S, Mohaddes SM, Hedayati M, Gorgian Mohammadi M, Dehbashi G.

Int J Mol Cell Med. 2013 Summer;2(3):143-50.


Antiprion compounds that reduce PrP(Sc) levels in dividing and stationary-phase cells.

Silber BM, Gever JR, Li Z, Gallardo-Godoy A, Renslo AR, Widjaja K, Irwin JJ, Rao S, Jacobson MP, Ghaemmaghami S, Prusiner SB.

Bioorg Med Chem. 2013 Dec 15;21(24):7999-8012. doi: 10.1016/j.bmc.2013.09.022. Epub 2013 Sep 18.


The optokinetic response as a quantitative measure of visual acuity in zebrafish.

Cameron DJ, Rassamdana F, Tam P, Dang K, Yanez C, Ghaemmaghami S, Dehkordi MI.

J Vis Exp. 2013 Oct 9;(80). doi: 10.3791/50832.


Strain specificity and drug resistance in anti-prion therapy.

Miller-Vedam L, Ghaemmaghami S.

Curr Top Med Chem. 2013;13(19):2397-406. Review.


Effects of infants' birth order, maternal age, and socio-economic status on birth weight.

Ghaemmaghami SJ, Nikniaz L, Mahdavi R, Nikniaz Z, Razmifard F, Afsharnia F.

Saudi Med J. 2013 Sep;34(9):949-53.


Adipocyte Derived Hormones Gene Expression, Resistin and Visfatin, in AGS Gastric Cancer Cell Line.

Gorgian Mohammadi M, Hedayati M, Zarghami N, Ghaemmaghami S, Mohaddes M.

Iran J Cancer Prev. 2013 Summer;6(3):165-9.


Sequence characterization of cDNA sequence of encoding of an antimicrobial Peptide with no disulfide bridge from the Iranian mesobuthus eupeus venomous glands.

Farajzadeh-Sheikh A, Jolodar A, Ghaemmaghami S.

Iran Red Crescent Med J. 2013 Jan;15(1):36-41. doi: 10.5812/ircmj.4024. Epub 2013 Jan 5.


Convergent replication of mouse synthetic prion strains.

Ghaemmaghami S, Colby DW, Nguyen HO, Hayashi S, Oehler A, DeArmond SJ, Prusiner SB.

Am J Pathol. 2013 Mar;182(3):866-74. doi: 10.1016/j.ajpath.2012.11.038.


Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice.

Nazor Friberg K, Hung G, Wancewicz E, Giles K, Black C, Freier S, Bennett F, Dearmond SJ, Freyman Y, Lessard P, Ghaemmaghami S, Prusiner SB.

Mol Ther Nucleic Acids. 2012 Feb 7;1:e9. doi: 10.1038/mtna.2011.6.


Pharmacokinetics of quinacrine efflux from mouse brain via the P-glycoprotein efflux transporter.

Ahn M, Ghaemmaghami S, Huang Y, Phuan PW, May BC, Giles K, DeArmond SJ, Prusiner SB.

PLoS One. 2012;7(7):e39112. doi: 10.1371/journal.pone.0039112. Epub 2012 Jul 2.


Compartment modeling for mammalian protein turnover studies by stable isotope metabolic labeling.

Guan S, Price JC, Ghaemmaghami S, Prusiner SB, Burlingame AL.

Anal Chem. 2012 May 1;84(9):4014-21. doi: 10.1021/ac203330z. Epub 2012 Apr 19.


A data processing pipeline for mammalian proteome dynamics studies using stable isotope metabolic labeling.

Guan S, Price JC, Prusiner SB, Ghaemmaghami S, Burlingame AL.

Mol Cell Proteomics. 2011 Dec;10(12):M111.010728. doi: 10.1074/mcp.M111.010728. Epub 2011 Sep 21.


Conformational transformation and selection of synthetic prion strains.

Ghaemmaghami S, Watts JC, Nguyen HO, Hayashi S, DeArmond SJ, Prusiner SB.

J Mol Biol. 2011 Oct 28;413(3):527-42. doi: 10.1016/j.jmb.2011.07.021. Epub 2011 Aug 4.


A survey of antiprion compounds reveals the prevalence of non-PrP molecular targets.

Poncet-Montange G, St Martin SJ, Bogatova OV, Prusiner SB, Shoichet BK, Ghaemmaghami S.

J Biol Chem. 2011 Aug 5;286(31):27718-28. doi: 10.1074/jbc.M111.234393. Epub 2011 May 24.


Video keyframe analysis using a segment-based statistical metric in a visually sensitive parametric space.

Omidyeganeh M, Ghaemmaghami S, Shirmohammadi S.

IEEE Trans Image Process. 2011 Oct;20(10):2730-7. doi: 10.1109/TIP.2011.2143421. Epub 2011 Apr 19.


Analysis of proteome dynamics in the mouse brain.

Price JC, Guan S, Burlingame A, Prusiner SB, Ghaemmaghami S.

Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14508-13. doi: 10.1073/pnas.1006551107. Erratum in: Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3645.


Discovery of 2-aminothiazoles as potent antiprion compounds.

Ghaemmaghami S, May BC, Renslo AR, Prusiner SB.

J Virol. 2010 Apr;84(7):3408-12. doi: 10.1128/JVI.02145-09. Epub 2009 Dec 23.


Continuous quinacrine treatment results in the formation of drug-resistant prions.

Ghaemmaghami S, Ahn M, Lessard P, Giles K, Legname G, DeArmond SJ, Prusiner SB.

PLoS Pathog. 2009 Nov;5(11):e1000673. doi: 10.1371/journal.ppat.1000673. Epub 2009 Nov 26.


Chemical induction of misfolded prion protein conformers in cell culture.

Ghaemmaghami S, Ullman J, Ahn M, St Martin S, Prusiner SB.

J Biol Chem. 2010 Apr 2;285(14):10415-23. doi: 10.1074/jbc.M109.045112. Epub 2009 Dec 2.


Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling.

Ingolia NT, Ghaemmaghami S, Newman JR, Weissman JS.

Science. 2009 Apr 10;324(5924):218-23. doi: 10.1126/science.1168978. Epub 2009 Feb 12.


Evaluation of the Root ZX apex locator in primary teeth.

Ghaemmaghami S, Eberle J, Duperon D.

Pediatr Dent. 2008 Nov-Dec;30(6):496-8.


Construction, verification and experimental use of two epitope-tagged collections of budding yeast strains.

Howson R, Huh WK, Ghaemmaghami S, Falvo JV, Bower K, Belle A, Dephoure N, Wykoff DD, Weissman JS, O'Shea EK.

Comp Funct Genomics. 2005;6(1-2):2-16. doi: 10.1002/cfg.449.


Cell division modulates prion accumulation in cultured cells.

Ghaemmaghami S, Phuan PW, Perkins B, Ullman J, May BC, Cohen FE, Prusiner SB.

Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):17971-6. Epub 2007 Nov 7.


Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise.

Newman JR, Ghaemmaghami S, Ihmels J, Breslow DK, Noble M, DeRisi JL, Weissman JS.

Nature. 2006 Jun 15;441(7095):840-6. Epub 2006 May 14.


Global analysis of protein expression in yeast.

Ghaemmaghami S, Huh WK, Bower K, Howson RW, Belle A, Dephoure N, O'Shea EK, Weissman JS.

Nature. 2003 Oct 16;425(6959):737-41.


A general mass spectrometry-based assay for the quantitation of protein-ligand binding interactions in solution.

Powell KD, Ghaemmaghami S, Wang MZ, Ma L, Oas TG, Fitzgerald MC.

J Am Chem Soc. 2002 Sep 4;124(35):10256-7. Erratum in: J Am Chem Soc. 2003 Apr 9;125(14):4398.


Quantitative protein stability measurement in vivo.

Ghaemmaghami S, Oas TG.

Nat Struct Biol. 2001 Oct;8(10):879-82.


A quantitative, high-throughput screen for protein stability.

Ghaemmaghami S, Fitzgerald MC, Oas TG.

Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8296-301.


Folding kinetics of a fluorescent variant of monomeric lambda repressor.

Ghaemmaghami S, Word JM, Burton RE, Richardson JS, Oas TG.

Biochemistry. 1998 Jun 23;37(25):9179-85.


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