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Items: 41


TIM-3 Dictates Functional Orientation of the Immune Infiltrate in Ovarian Cancer.

Fucikova J, Rakova J, Hensler M, Kasikova L, Belicova L, Hladikova K, Truxova I, Skapa P, Laco J, Pecen L, Praznovec I, Halaska MJ, Brtnicky T, Kodet R, Fialova A, Pineau J, Gey A, Tartour E, Ryska A, Galluzzi L, Spisek R.

Clin Cancer Res. 2019 Aug 1;25(15):4820-4831. doi: 10.1158/1078-0432.CCR-18-4175. Epub 2019 May 10.


Absolute numbers of regulatory T cells and neutrophils in corticosteroid-free patients are predictive for response to bevacizumab in recurrent glioblastoma patients.

Quillien V, Carpentier AF, Gey A, Avril T, Tartour E, Sejalon F, Campillo-Gimenez B, Vauleon E.

Cancer Immunol Immunother. 2019 Jun;68(6):871-882. doi: 10.1007/s00262-019-02317-9. Epub 2019 Mar 4.


Adverse events need for hospitalization and systemic immunosuppression in very elderly patients (over 80 years) treated with ipilimumab for metastatic melanoma.

Leroy V, Gerard E, Dutriaux C, Prey S, Gey A, Mertens C, Beylot-Barry M, Pham-Ledard A.

Cancer Immunol Immunother. 2019 Apr;68(4):545-551. doi: 10.1007/s00262-019-02298-9. Epub 2019 Jan 19.


High Therapeutic Efficacy of a New Survivin LSP-Cancer Vaccine Containing CD4+ and CD8+ T-Cell Epitopes.

Onodi F, Maherzi-Mechalikh C, Mougel A, Ben Hamouda N, Taboas C, Gueugnon F, Tran T, Nozach H, Marcon E, Gey A, Terme M, Bouzidi A, Maillere B, Kerzerho J, Tartour E, Tanchot C.

Front Oncol. 2018 Nov 13;8:517. doi: 10.3389/fonc.2018.00517. eCollection 2018.


Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells.

Granier C, Vinatier E, Colin E, Mandavit M, Dariane C, Verkarre V, Biard L, El Zein R, Lesaffre C, Galy-Fauroux I, Roussel H, De Guillebon E, Blanc C, Saldmann A, Badoual C, Gey A, Tartour É.

J Vis Exp. 2018 Feb 8;(132). doi: 10.3791/56606.


[Tim-3: a novel biomarker and therapeutic target in oncology].

Granier C, Gey A, Dariane C, Mejean A, Timsit MO, Blanc C, Verkarre V, Radulescu C, Fabre E, Vano Y, Oudard S, Badoual C, Tartour É.

Med Sci (Paris). 2018 Mar;34(3):231-237. doi: 10.1051/medsci/20183403011. Epub 2018 Mar 16. Review. French.


[Recurrent frontal swelling in a child].

Gey A, Scheller C, Kunze C, Pazaitis N, Stiefel M, Plontke S.

HNO. 2018 Aug;66(8):626-630. doi: 10.1007/s00106-018-0481-x. German. No abstract available.


Mechanisms of action and rationale for the use of checkpoint inhibitors in cancer.

Granier C, De Guillebon E, Blanc C, Roussel H, Badoual C, Colin E, Saldmann A, Gey A, Oudard S, Tartour E.

ESMO Open. 2017 Jul 3;2(2):e000213. doi: 10.1136/esmoopen-2017-000213. eCollection 2017. Review.


Composite biomarkers defined by multiparametric immunofluorescence analysis identify ALK-positive adenocarcinoma as a potential target for immunotherapy.

Roussel H, De Guillebon E, Biard L, Mandavit M, Gibault L, Fabre E, Antoine M, Hofman P, Beau-Faller M, Blons H, Danel C, Barthes FLP, Gey A, Granier C, Wislez M, Laurent-Puig P, Oudard S, Bruneval P, Badoual C, Cadranel J, Tartour E.

Oncoimmunology. 2017 Feb 21;6(4):e1286437. doi: 10.1080/2162402X.2017.1286437. eCollection 2017.


Tim-3 Expression on Tumor-Infiltrating PD-1+CD8+ T Cells Correlates with Poor Clinical Outcome in Renal Cell Carcinoma.

Granier C, Dariane C, Combe P, Verkarre V, Urien S, Badoual C, Roussel H, Mandavit M, Ravel P, Sibony M, Biard L, Radulescu C, Vinatier E, Benhamouda N, Peyromaure M, Oudard S, Méjean A, Timsit MO, Gey A, Tartour E.

Cancer Res. 2017 Mar 1;77(5):1075-1082. doi: 10.1158/0008-5472.CAN-16-0274. Epub 2016 Nov 21.


IL-15 Trans-Signaling with the Superagonist RLI Promotes Effector/Memory CD8+ T Cell Responses and Enhances Antitumor Activity of PD-1 Antagonists.

Desbois M, Le Vu P, Coutzac C, Marcheteau E, Béal C, Terme M, Gey A, Morisseau S, Teppaz G, Boselli L, Jacques Y, Béchard D, Tartour E, Cassard L, Chaput N.

J Immunol. 2016 Jul 1;197(1):168-78. doi: 10.4049/jimmunol.1600019. Epub 2016 May 23.


A Therapeutic Her2/neu Vaccine Targeting Dendritic Cells Preferentially Inhibits the Growth of Low Her2/neu-Expressing Tumor in HLA-A2 Transgenic Mice.

Tran T, Diniz MO, Dransart E, Gey A, Merillon N, Lone YC, Godefroy S, Sibley C, Ferreira LC, Medioni J, Oudard S, Johannes L, Tartour E.

Clin Cancer Res. 2016 Aug 15;22(16):4133-44. doi: 10.1158/1078-0432.CCR-16-0044. Epub 2016 Mar 22.


Granulocytic myeloid-derived suppressor cells inversely correlate with plasma arginine and overall survival in critically ill patients.

Gey A, Tadie JM, Caumont-Prim A, Hauw-Berlemont C, Cynober L, Fagon JY, Terme M, Diehl JL, Delclaux C, Tartour E.

Clin Exp Immunol. 2015 May;180(2):280-8. doi: 10.1111/cei.12567.


Severe cutaneous adverse reaction associated with vemurafenib: DRESS, AGEP or overlap reaction?

Gey A, Milpied B, Dutriaux C, Mateus C, Robert C, Perro G, Taieb A, Ezzedine K, Jouary T.

J Eur Acad Dermatol Venereol. 2016 Jan;30(1):178-9. doi: 10.1111/jdv.12685. Epub 2014 Aug 29. No abstract available.


Stay in NICU and infantile haemangioma development.

Gey A, Ezzedine K, Diallo A, Prey S, Dreyfus I, Maza A, Mazereeuw-Hautier J, Taïeb A, Léauté-Labrèze C.

J Eur Acad Dermatol Venereol. 2015 Mar;29(3):566-73. doi: 10.1111/jdv.12639. Epub 2014 Aug 4.


Clinical validation of IFNγ/IL-10 and IFNγ/IL-2 FluoroSpot assays for the detection of Tr1 T cells and influenza vaccine monitoring in humans.

Chauvat A, Benhamouda N, Gey A, Lemoine FM, Paulie S, Carrat F, Gougeon ML, Rozenberg F, Krivine A, Cherai M, Lehmann P 5th, Quintin-Colonna F, Launay O, Tartour E.

Hum Vaccin Immunother. 2014;10(1):104-13. doi: 10.4161/hv.26593. Epub 2013 Oct 1.


[PD-1 and PDL-1 expression in cancer: significance and prognostic value].

Badoual C, Combe P, Gey A, Granier C, Roussel H, De Guillebon E, Oudard S, Tartour E.

Med Sci (Paris). 2013 Jun-Jul;29(6-7):570-2. doi: 10.1051/medsci/2013296005. Epub 2013 Jul 12. French. No abstract available.


Arginine administration to critically ill patients with a low nitric oxide fraction in the airways: a pilot study.

Tadié JM, Cynober L, Peigne V, Caumont-Prim A, Neveux N, Gey A, Guerot E, Diehl JL, Fagon JY, Tartour E, Delclaux C.

Intensive Care Med. 2013 Sep;39(9):1663-5. doi: 10.1007/s00134-013-2984-y. Epub 2013 Jun 19. No abstract available.


Identification of pathogens in mastitis milk samples with fluorescent in situ hybridization.

Gey A, Werckenthin C, Poppert S, Straubinger RK.

J Vet Diagn Invest. 2013 May;25(3):386-94. doi: 10.1177/1040638713486113. Epub 2013 Apr 30.


Mucosal imprinting of vaccine-induced CD8⁺ T cells is crucial to inhibit the growth of mucosal tumors.

Sandoval F, Terme M, Nizard M, Badoual C, Bureau MF, Freyburger L, Clement O, Marcheteau E, Gey A, Fraisse G, Bouguin C, Merillon N, Dransart E, Tran T, Quintin-Colonna F, Autret G, Thiebaud M, Suleman M, Riffault S, Wu TC, Launay O, Danel C, Taieb J, Richardson J, Zitvogel L, Fridman WH, Johannes L, Tartour E.

Sci Transl Med. 2013 Feb 13;5(172):172ra20. doi: 10.1126/scitranslmed.3004888. Erratum in: Sci Transl Med. 2013 Mar 27;5(178):178er2. Suleman, Muhammed [corrected to Suleman, Muhammad].


Autoimmune thyroid disease in vitiligo: multivariate analysis indicates intricate pathomechanisms.

Gey A, Diallo A, Seneschal J, Léauté-Labrèze C, Boralevi F, Jouary T, Taieb A, Ezzedine K.

Br J Dermatol. 2013 Apr;168(4):756-61. doi: 10.1111/bjd.12166.


PD-1-expressing tumor-infiltrating T cells are a favorable prognostic biomarker in HPV-associated head and neck cancer.

Badoual C, Hans S, Merillon N, Van Ryswick C, Ravel P, Benhamouda N, Levionnois E, Nizard M, Si-Mohamed A, Besnier N, Gey A, Rotem-Yehudar R, Pere H, Tran T, Guerin CL, Chauvat A, Dransart E, Alanio C, Albert S, Barry B, Sandoval F, Quintin-Colonna F, Bruneval P, Fridman WH, Lemoine FM, Oudard S, Johannes L, Olive D, Brasnu D, Tartour E.

Cancer Res. 2013 Jan 1;73(1):128-38. doi: 10.1158/0008-5472.CAN-12-2606. Epub 2012 Nov 7.


Pitfalls in anti-influenza T cell detection by Elispot using thimerosal containing pandemic H1N1 vaccine as antigen.

Chauvat A, Benhamouda N, Loison E, Gougeon ML, Gey A, Levionnois E, Ravel P, Abitbol V, Roncelin S, Marcheteau E, Quintin-Colonna F, Fridman WH, Launay O, Tartour E.

J Immunol Methods. 2012 Apr 30;378(1-2):81-7. doi: 10.1016/j.jim.2012.02.008. Epub 2012 Feb 16.


Rapid identification of the animal pathogens Streptococcus uberis and Arcanobacterium pyogenes by fluorescence in situ hybridization (FISH).

Werckenthin C, Gey A, Straubinger RK, Poppert S.

Vet Microbiol. 2012 May 4;156(3-4):330-5. doi: 10.1016/j.vetmic.2011.10.007. Epub 2011 Oct 15.


A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens.

Pere H, Montier Y, Bayry J, Quintin-Colonna F, Merillon N, Dransart E, Badoual C, Gey A, Ravel P, Marcheteau E, Batteux F, Sandoval F, Adotevi O, Chiu C, Garcia S, Tanchot C, Lone YC, Ferreira LC, Nelson BH, Hanahan D, Fridman WH, Johannes L, Tartour E.

Blood. 2011 Nov 3;118(18):4853-62. doi: 10.1182/blood-2011-01-329656. Epub 2011 Sep 9.


Better understanding tumor-host interaction in head and neck cancer to improve the design and development of immunotherapeutic strategies.

Badoual C, Sandoval F, Pere H, Hans S, Gey A, Merillon N, Van Ryswick C, Quintin-Colonna F, Bruneval P, Brasnu D, Fridman WH, Tartour E.

Head Neck. 2010 Jul;32(7):946-58. doi: 10.1002/hed.21346. Review.


The soluble alpha chain of interleukin-15 receptor: a proinflammatory molecule associated with tumor progression in head and neck cancer.

Badoual C, Bouchaud G, Agueznay Nel H, Mortier E, Hans S, Gey A, Fernani F, Peyrard S, -Puig PL, Bruneval P, Sastre X, Plet A, Garrigue-Antar L, Quintin-Colonna F, Fridman WH, Brasnu D, Jacques Y, Tartour E.

Cancer Res. 2008 May 15;68(10):3907-14. doi: 10.1158/0008-5472.CAN-07-6842.


Soluble interleukin-2 receptor and metalloproteinase-9 expression in head and neck cancer: prognostic value and analysis of their relationships.

El Houda Agueznay N, Badoual C, Hans S, Gey A, Vingert B, Peyrard S, Quintin-Colonna F, Ravel P, Bruneval P, Roncelin S, Lelongt B, Bertoglio J, Fridman WH, Brasnu D, Tartour E.

Clin Exp Immunol. 2007 Oct;150(1):114-23. Epub 2007 Aug 3.


Optimization of an elispot assay to detect cytomegalovirus-specific CD8+ T lymphocytes.

Godard B, Gazagne A, Gey A, Baptiste M, Vingert B, Pegaz-Fiornet B, Strompf L, Fridman WH, Glotz D, Tartour E.

Hum Immunol. 2004 Nov;65(11):1307-18.


Identification and characterisation of a group of cervical carcinoma patients with profound downregulation of intratumoral Type 1 (IFNgamma) and Type 2 (IL-4) cytokine mRNA expression.

Gey A, Kumari P, Sambandam A, Lecuru F, Cassard L, Badoual C, Fridman C, Nagarajan B, Fridman WH, Tartour E.

Eur J Cancer. 2003 Mar;39(5):595-603.


Interleukin-17 inhibits tumor cell growth by means of a T-cell-dependent mechanism.

Benchetrit F, Ciree A, Vives V, Warnier G, Gey A, Sautès-Fridman C, Fossiez F, Haicheur N, Fridman WH, Tartour E.

Blood. 2002 Mar 15;99(6):2114-21.


[In situ PCR].

Tartour E, Gey A, Hamdi S, Vielh P, Nagarajan B, Fridman WH.

Ann Pathol. 2000 May;20(3):213-20. Review. French. No abstract available.


Development of a direct in situ RT-PCR method using labeled primers to detect cytokine mRNA inside cells.

Gey A, Hamdi S, Vielh P, Mehtali M, Fridman WH, Tartour E.

J Immunol Methods. 1999 Jul 30;227(1-2):149-60.


Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice.

Tartour E, Fossiez F, Joyeux I, Galinha A, Gey A, Claret E, Sastre-Garau X, Couturier J, Mosseri V, Vives V, Banchereau J, Fridman WH, Wijdenes J, Lebecque S, Sautès-Fridman C.

Cancer Res. 1999 Aug 1;59(15):3698-704.


In vivo induction of functional Fc gammaRI (CD64) on neutrophils and modulation of blood cytokine mRNA levels in cancer patients treated with G-CSF (rMetHuG-CSF).

Michon JM, Gey A, Moutel S, Tartour E, Meresse V, Fridman W, Teillaud JL.

Br J Haematol. 1998 Mar;100(3):550-6.


Prognostic value of intratumoral interferon gamma messenger RNA expression in invasive cervical carcinomas.

Tartour E, Gey A, Sastre-Garau X, Lombard Surin I, Mosseri V, Fridman WH.

J Natl Cancer Inst. 1998 Feb 18;90(4):287-94.


Macrophage inflammatory protein-1alpha is induced by human immunodeficiency virus infection of monocyte-derived macrophages.

Canque B, Rosenzwajg M, Gey A, Tartour E, Fridman WH, Gluckman JC.

Blood. 1996 Mar 1;87(5):2011-9.


PCR-based analysis of the murine immunoglobulin heavy-chain repertoire.

Delassus S, Gey A, Darche S, Cumano A, Roth C, Kourilsky P.

J Immunol Methods. 1995 Aug 18;184(2):219-29.


Phenotypic and functional analysis of tumour-infiltrating lymphocytes from patients with melanoma and other metastatic cancers.

Mathiot C, Robin E, Gey A, Weng X, Dorval T, Pouillart P, Sastre X, Zerbib M, Hamelin JP, Salmon R, et al.

Eur J Cancer. 1992;28(2-3):345-50.


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