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Items: 1 to 50 of 182

1.

Adaptive Immunity Induces Tolerance to Flagellin by Attenuating TLR5 and NLRC4-Mediated Innate Immune Responses.

Yeoh BS, Gewirtz AT, Vijay-Kumar M.

Front Cell Infect Microbiol. 2019 Feb 19;9:29. doi: 10.3389/fcimb.2019.00029. eCollection 2019.

2.

Chronic inflammatory diseases: Are we ready for microbiota-based dietary intervention?

Viennois E, Gewirtz AT, Chassaing B.

Cell Mol Gastroenterol Hepatol. 2019 Mar 2. pii: S2352-345X(19)30024-4. doi: 10.1016/j.jcmgh.2019.02.008. [Epub ahead of print] Review.

3.

Deoxyribonuclease I Activity, Cell-Free DNA, and Risk of Liver Cancer in a Prospective Cohort.

Golonka RM, Yeoh BS, Petrick JL, Weinstein SJ, Albanes D, Gewirtz AT, McGlynn KA, Vijay-Kumar M.

JNCI Cancer Spectr. 2018 Dec;2(4):pky083. doi: 10.1093/jncics/pky083. Epub 2019 Feb 21.

4.

Early-Life Microbiota Exposure Restricts Myeloid-Derived Suppressor Cell-Driven Colonic Tumorigenesis.

Harusato A, Viennois E, Etienne-Mesmin L, Matsuyama S, Abo H, Osuka S, Lukacs NW, Naito Y, Itoh Y, Li JD, Merlin D, Gewirtz AT, Denning TL.

Cancer Immunol Res. 2019 Feb 19. doi: 10.1158/2326-6066.CIR-18-0444. [Epub ahead of print]

PMID:
30782668
5.

Microbiota fermentation-NLRP3 axis shapes the impact of dietary fibres on intestinal inflammation.

Singh V, Yeoh BS, Walker RE, Xiao X, Saha P, Golonka RM, Cai J, Bretin ACA, Cheng X, Liu Q, Flythe MD, Chassaing B, Shearer GC, Patterson AD, Gewirtz AT, Vijay-Kumar M.

Gut. 2019 Jan 22. pii: gutjnl-2018-316250. doi: 10.1136/gutjnl-2018-316250. [Epub ahead of print]

PMID:
30670576
6.

Dietary emulsifiers consumption alters anxiety-like and social-related behaviors in mice in a sex-dependent manner.

Holder MK, Peters NV, Whylings J, Fields CT, Gewirtz AT, Chassaing B, de Vries GJ.

Sci Rep. 2019 Jan 17;9(1):172. doi: 10.1038/s41598-018-36890-3.

7.

Bacterial Translocation and Risk of Liver Cancer in a Finnish Cohort.

Yang B, Petrick JL, Thistle JE, Pinto LA, Kemp TJ, Tran HQ, Gewirtz AT, Waterboer T, Fedirko V, Jenab M, Graubard BI, Weinstein SJ, Albanes D, McGlynn KA.

Cancer Epidemiol Biomarkers Prev. 2019 Jan 2. doi: 10.1158/1055-9965.EPI-18-0240. [Epub ahead of print]

PMID:
30602499
8.

Aluminum Meddles With Visceral Pain Perception.

Bretin A, Gewirtz AT.

Cell Mol Gastroenterol Hepatol. 2019;7(1):235-236. doi: 10.1016/j.jcmgh.2018.10.005. Epub 2018 Oct 30. No abstract available.

9.

Identification of Inner Mucus-Associated Bacteria by Laser Capture Microdissection.

Chassaing B, Gewirtz AT.

Cell Mol Gastroenterol Hepatol. 2018 Sep 17;7(1):157-160. doi: 10.1016/j.jcmgh.2018.09.009. eCollection 2019. No abstract available.

10.

Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer.

Singh V, Yeoh BS, Chassaing B, Xiao X, Saha P, Aguilera Olvera R, Lapek JD Jr, Zhang L, Wang WB, Hao S, Flythe MD, Gonzalez DJ, Cani PD, Conejo-Garcia JR, Xiong N, Kennett MJ, Joe B, Patterson AD, Gewirtz AT, Vijay-Kumar M.

Cell. 2018 Oct 18;175(3):679-694.e22. doi: 10.1016/j.cell.2018.09.004.

PMID:
30340040
11.

Biomarkers of maternal environmental enteric dysfunction are associated with shorter gestation and reduced length in newborn infants in Uganda.

Lauer JM, Duggan CP, Ausman LM, Griffiths JK, Webb P, Agaba E, Nshakira N, Tran HQ, Gewirtz AT, Ghosh S.

Am J Clin Nutr. 2018 Oct 1;108(4):889-896. doi: 10.1093/ajcn/nqy176.

12.

Publisher Correction: Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.

Fulde M, Sommer F, Chassaing B, van Vorst K, Dupont A, Hensel M, Basic M, Klopfleisch R, Rosenstiel P, Bleich A, Bäckhed F, Gewirtz AT, Hornef MW.

Nature. 2018 Nov;563(7731):E25. doi: 10.1038/s41586-018-0507-2.

PMID:
30158704
13.

Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.

Fulde M, Sommer F, Chassaing B, van Vorst K, Dupont A, Hensel M, Basic M, Klopfleisch R, Rosenstiel P, Bleich A, Bäckhed F, Gewirtz AT, Hornef MW.

Nature. 2018 Aug;560(7719):489-493. doi: 10.1038/s41586-018-0395-5. Epub 2018 Aug 8. Erratum in: Nature. 2018 Nov;563(7731):E25.

PMID:
30089902
14.

A cytokine network involving IL-36γ, IL-23, and IL-22 promotes antimicrobial defense and recovery from intestinal barrier damage.

Ngo VL, Abo H, Maxim E, Harusato A, Geem D, Medina-Contreras O, Merlin D, Gewirtz AT, Nusrat A, Denning TL.

Proc Natl Acad Sci U S A. 2018 May 29;115(22):E5076-E5085. doi: 10.1073/pnas.1718902115. Epub 2018 May 14.

15.

Corrigendum to "Acute and repeated exposure to social stress reduces gut microbiota diversity in Syrian hamsters" [Behav. Brain Res. 345 (2018) 39-48].

Partrick KA, Chassaing B, Beach LQ, McCann KE, Gewirtz AT, Huhman KL.

Behav Brain Res. 2018 Aug 1;348:277. doi: 10.1016/j.bbr.2018.03.044. Epub 2018 Apr 16.

PMID:
29673868
16.

Mice harboring pathobiont-free microbiota do not develop intestinal inflammation that normally results from an innate immune deficiency.

Chassaing B, Gewirtz AT.

PLoS One. 2018 Apr 4;13(4):e0195310. doi: 10.1371/journal.pone.0195310. eCollection 2018.

17.

Markers of Environmental Enteric Dysfunction Are Associated With Neurodevelopmental Outcomes in Tanzanian Children.

Etheredge AJ, Manji K, Kellogg M, Tran H, Liu E, McDonald CM, Kisenge R, Aboud S, Fawzi W, Bellinger D, Gewirtz AT, Duggan CP.

J Pediatr Gastroenterol Nutr. 2018 Jun;66(6):953-959. doi: 10.1097/MPG.0000000000001978.

PMID:
29613921
18.

Not so Splendid for the Gut Microbiota.

Chassaing B, Gewirtz AT.

Inflamm Bowel Dis. 2018 Apr 23;24(5):1055-1056. doi: 10.1093/ibd/izy072.

19.

Together Forever: Bacterial-Viral Interactions in Infection and Immunity.

Shi Z, Gewirtz AT.

Viruses. 2018 Mar 10;10(3). pii: E122. doi: 10.3390/v10030122. Review.

20.

Microbiota and metabolism: what's new in 2018?

Bretin A, Gewirtz AT, Chassaing B.

Am J Physiol Endocrinol Metab. 2018 Jul 1;315(1):E1-E6. doi: 10.1152/ajpendo.00014.2018. Epub 2018 Feb 27.

PMID:
29486139
21.

Acute and repeated exposure to social stress reduces gut microbiota diversity in Syrian hamsters.

Partrick KA, Chassaing B, Beach LQ, McCann KE, Gewirtz AT, Huhman KL.

Behav Brain Res. 2018 Jun 1;345:39-48. doi: 10.1016/j.bbr.2018.02.005. Epub 2018 Feb 21. No abstract available. Erratum in: Behav Brain Res. 2018 Apr 16;:.

PMID:
29474810
22.

Effects of gut-derived endotoxin on anxiety-like and repetitive behaviors in male and female mice.

Fields CT, Chassaing B, Castillo-Ruiz A, Osan R, Gewirtz AT, de Vries GJ.

Biol Sex Differ. 2018 Jan 19;9(1):7. doi: 10.1186/s13293-018-0166-x.

23.

TLR5 signaling in murine bone marrow induces hematopoietic progenitor cell proliferation and aids survival from radiation.

Zhang B, Oyewole-Said D, Zou J, Willliams IR, Gewirtz AT.

Blood Adv. 2017 Sep 14;1(21):1796-1806. doi: 10.1182/bloodadvances.2017006981. eCollection 2017 Sep 26.

24.

Fiber-Mediated Nourishment of Gut Microbiota Protects against Diet-Induced Obesity by Restoring IL-22-Mediated Colonic Health.

Zou J, Chassaing B, Singh V, Pellizzon M, Ricci M, Fythe MD, Kumar MV, Gewirtz AT.

Cell Host Microbe. 2018 Jan 10;23(1):41-53.e4. doi: 10.1016/j.chom.2017.11.003. Epub 2017 Dec 21.

25.

Bolus Weekly Vitamin D3 Supplementation Impacts Gut and Airway Microbiota in Adults With Cystic Fibrosis: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial.

Kanhere M, He J, Chassaing B, Ziegler TR, Alvarez JA, Ivie EA, Hao L, Hanfelt J, Gewirtz AT, Tangpricha V.

J Clin Endocrinol Metab. 2018 Feb 1;103(2):564-574. doi: 10.1210/jc.2017-01983.

26.

How diet can impact gut microbiota to promote or endanger health.

Chassaing B, Vijay-Kumar M, Gewirtz AT.

Curr Opin Gastroenterol. 2017 Nov;33(6):417-421. doi: 10.1097/MOG.0000000000000401. Review.

27.

The microbiota influences cell death and microglial colonization in the perinatal mouse brain.

Castillo-Ruiz A, Mosley M, George AJ, Mussaji LF, Fullerton EF, Ruszkowski EM, Jacobs AJ, Gewirtz AT, Chassaing B, Forger NG.

Brain Behav Immun. 2018 Jan;67:218-229. doi: 10.1016/j.bbi.2017.08.027. Epub 2017 Sep 7.

28.

Vasopressin deletion is associated with sex-specific shifts in the gut microbiome.

Fields CT, Chassaing B, Paul MJ, Gewirtz AT, de Vries GJ.

Gut Microbes. 2018 Jan 2;9(1):13-25. doi: 10.1080/19490976.2017.1356557. Epub 2017 Aug 11.

29.

Colonic Microbiota Encroachment Correlates With Dysglycemia in Humans.

Chassaing B, Raja SM, Lewis JD, Srinivasan S, Gewirtz AT.

Cell Mol Gastroenterol Hepatol. 2017 Apr 13;4(2):205-221. doi: 10.1016/j.jcmgh.2017.04.001. eCollection 2017 Sep.

30.

Supplementation of Low- and High-fat Diets with Fermentable Fiber Exacerbates Severity of DSS-induced Acute Colitis.

Miles JP, Zou J, Kumar MV, Pellizzon M, Ulman E, Ricci M, Gewirtz AT, Chassaing B.

Inflamm Bowel Dis. 2017 Jul;23(7):1133-1143. doi: 10.1097/MIB.0000000000001155.

31.

Infant Nutritional Status and Markers of Environmental Enteric Dysfunction are Associated with Midchildhood Anthropometry and Blood Pressure in Tanzania.

Locks LM, Mwiru RS, Mtisi E, Manji KP, McDonald CM, Liu E, Kupka R, Kisenge R, Aboud S, Gosselin K, Gillman M, Gewirtz AT, Fawzi WW, Duggan CP.

J Pediatr. 2017 Aug;187:225-233.e1. doi: 10.1016/j.jpeds.2017.04.005. Epub 2017 May 9.

32.

Genome Sequence of a Toxin-Positive Clostridium difficile Strain Isolated from Murine Feces.

Etienne-Mesmin L, Chassaing B, Adekunle O, Mattei LM, Edwards AN, McBride SM, Bushman FD, Gewirtz AT.

Genome Announc. 2017 Apr 6;5(14). pii: e00088-17. doi: 10.1128/genomeA.00088-17.

33.

Exposure to bacterial products lipopolysaccharide and flagellin and hepatocellular carcinoma: a nested case-control study.

Fedirko V, Tran HQ, Gewirtz AT, Stepien M, Trichopoulou A, Aleksandrova K, Olsen A, Tjønneland A, Overvad K, Carbonnel F, Boutron-Ruault MC, Severi G, Kühn T, Kaaks R, Boeing H, Bamia C, Lagiou P, Grioni S, Panico S, Palli D, Tumino R, Naccarati A, Peeters PH, Bueno-de-Mesquita HB, Weiderpass E, Castaño JM, Barricarte A, Sánchez MJ, Dorronsoro M, Quirós JR, Agudo A, Sjöberg K, Ohlsson B, Hemmingsson O, Werner M, Bradbury KE, Khaw KT, Wareham N, Tsilidis KK, Aune D, Scalbert A, Romieu I, Riboli E, Jenab M.

BMC Med. 2017 Apr 4;15(1):72. doi: 10.1186/s12916-017-0830-8.

34.

IL-36γ signaling controls the induced regulatory T cell-Th9 cell balance via NFκB activation and STAT transcription factors.

Harusato A, Abo H, Ngo VL, Yi SW, Mitsutake K, Osuka S, Kohlmeier JE, Li JD, Gewirtz AT, Nusrat A, Denning TL.

Mucosal Immunol. 2017 Nov;10(6):1455-1467. doi: 10.1038/mi.2017.21. Epub 2017 Mar 22.

35.

Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation.

Chassaing B, Van de Wiele T, De Bodt J, Marzorati M, Gewirtz AT.

Gut. 2017 Aug;66(8):1414-1427. doi: 10.1136/gutjnl-2016-313099. Epub 2017 Mar 21.

36.

Toxin-positive Clostridium difficile latently infect mouse colonies and protect against highly pathogenic C. difficile.

Etienne-Mesmin L, Chassaing B, Adekunle O, Mattei LM, Bushman FD, Gewirtz AT.

Gut. 2018 May;67(5):860-871. doi: 10.1136/gutjnl-2016-313510. Epub 2017 Feb 20.

PMID:
28219893
37.

Tryptophan: A gut microbiota-derived metabolites regulating inflammation.

Etienne-Mesmin L, Chassaing B, Gewirtz AT.

World J Gastrointest Pharmacol Ther. 2017 Feb 6;8(1):7-9. doi: 10.4292/wjgpt.v8.i1.7. Review.

38.

Hepatocyte Toll-Like Receptor 5 Promotes Bacterial Clearance and Protects Mice Against High-Fat Diet-Induced Liver Disease.

Etienne-Mesmin L, Vijay-Kumar M, Gewirtz AT, Chassaing B.

Cell Mol Gastroenterol Hepatol. 2016 May 5;2(5):584-604. doi: 10.1016/j.jcmgh.2016.04.007. eCollection 2016 Sep.

39.

Western diet induces colonic nitrergic myenteric neuropathy and dysmotility in mice via saturated fatty acid- and lipopolysaccharide-induced TLR4 signalling.

Reichardt F, Chassaing B, Nezami BG, Li G, Tabatabavakili S, Mwangi S, Uppal K, Liang B, Vijay-Kumar M, Jones D, Gewirtz AT, Srinivasan S.

J Physiol. 2017 Mar 1;595(5):1831-1846. doi: 10.1113/JP273269. Epub 2017 Feb 8.

40.

Swimming Motility Mediates the Formation of Neutrophil Extracellular Traps Induced by Flagellated Pseudomonas aeruginosa.

Floyd M, Winn M, Cullen C, Sil P, Chassaing B, Yoo DG, Gewirtz AT, Goldberg JB, McCarter LL, Rada B.

PLoS Pathog. 2016 Nov 17;12(11):e1005987. doi: 10.1371/journal.ppat.1005987. eCollection 2016 Nov.

41.

Dietary Emulsifier-Induced Low-Grade Inflammation Promotes Colon Carcinogenesis.

Viennois E, Merlin D, Gewirtz AT, Chassaing B.

Cancer Res. 2017 Jan 1;77(1):27-40. doi: 10.1158/0008-5472.CAN-16-1359. Epub 2016 Nov 7.

42.

Role of vitamin D on gut microbiota in cystic fibrosis.

Kanhere M, Chassaing B, Gewirtz AT, Tangpricha V.

J Steroid Biochem Mol Biol. 2018 Jan;175:82-87. doi: 10.1016/j.jsbmb.2016.11.001. Epub 2016 Nov 3. Review.

43.

IL-17A-mediated neutrophil recruitment limits expansion of segmented filamentous bacteria.

Flannigan KL, Ngo VL, Geem D, Harusato A, Hirota SA, Parkos CA, Lukacs NW, Nusrat A, Gaboriau-Routhiau V, Cerf-Bensussan N, Gewirtz AT, Denning TL.

Mucosal Immunol. 2017 May;10(3):673-684. doi: 10.1038/mi.2016.80. Epub 2016 Sep 14.

44.

Contribution of Mesenteric Lymph Nodes and GALT to the Intestinal Foxp3+ Regulatory T-Cell Compartment.

Geem D, Ngo V, Harusato A, Chassaing B, Gewirtz AT, Newberry RD, Denning TL.

Cell Mol Gastroenterol Hepatol. 2016 May;2(3):274-280.

45.

Corralling Colonic Flagellated Microbiota.

Ley RE, Gewirtz AT.

N Engl J Med. 2016 Jul 7;375(1):85-7. doi: 10.1056/NEJMcibr1604801. No abstract available.

PMID:
27406353
46.

Corrigendum: Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome.

Chassaing B, Koren O, Goodrich JK, Poole AC, Srinivasan S, Ley RE, Gewirtz AT.

Nature. 2016 Aug 11;536(7615):238. doi: 10.1038/nature18000. Epub 2016 May 4. No abstract available.

PMID:
27144359
47.

Elevations in serum anti-flagellin and anti-LPS Igs are related to growth faltering in young Tanzanian children.

McDonald CM, Manji KP, Gosselin K, Tran H, Liu E, Kisenge R, Aboud S, Fawzi WW, Gewirtz AT, Duggan CP.

Am J Clin Nutr. 2016 Jun;103(6):1548-54. doi: 10.3945/ajcn.116.131409. Epub 2016 Apr 27.

48.

Sex steroid deficiency-associated bone loss is microbiota dependent and prevented by probiotics.

Li JY, Chassaing B, Tyagi AM, Vaccaro C, Luo T, Adams J, Darby TM, Weitzmann MN, Mulle JG, Gewirtz AT, Jones RM, Pacifici R.

J Clin Invest. 2016 Jun 1;126(6):2049-63. doi: 10.1172/JCI86062. Epub 2016 Apr 25.

49.

Absence of TLR11 in Mice Does Not Confer Susceptibility to Salmonella Typhi.

Song J, Wilhelm CL, Wangdi T, Maira-Litran T, Lee SJ, Raetz M, Sturge CR, Mirpuri J, Pei J, Grishin NV, McSorley SJ, Gewirtz AT, Bäumler AJ, Pier GB, Galán JE, Yarovinsky F.

Cell. 2016 Feb 25;164(5):827-8. doi: 10.1016/j.cell.2016.02.015. No abstract available.

50.

A Novel Vaccination Strategy Mediating the Induction of Lung-Resident Memory CD8 T Cells Confers Heterosubtypic Immunity against Future Pandemic Influenza Virus.

Lee YN, Lee YT, Kim MC, Gewirtz AT, Kang SM.

J Immunol. 2016 Mar 15;196(6):2637-45. doi: 10.4049/jimmunol.1501637. Epub 2016 Feb 10.

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