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Items: 18


Live-cell analysis of endogenous GFP-RPB1 uncovers rapid turnover of initiating and promoter-paused RNA Polymerase II.

Steurer B, Janssens RC, Geverts B, Geijer ME, Wienholz F, Theil AF, Chang J, Dealy S, Pothof J, van Cappellen WA, Houtsmuller AB, Marteijn JA.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4368-E4376. doi: 10.1073/pnas.1717920115. Epub 2018 Apr 9.


The Effect of F877L and T878A Mutations on Androgen Receptor Response to Enzalutamide.

Prekovic S, van Royen ME, Voet AR, Geverts B, Houtman R, Melchers D, Zhang KY, Van den Broeck T, Smeets E, Spans L, Houtsmuller AB, Joniau S, Claessens F, Helsen C.

Mol Cancer Ther. 2016 Jul;15(7):1702-12. doi: 10.1158/1535-7163.MCT-15-0892. Epub 2016 May 16.


Analysis of biomolecular dynamics by FRAP and computer simulation.

Geverts B, van Royen ME, Houtsmuller AB.

Methods Mol Biol. 2015;1251:109-33. doi: 10.1007/978-1-4939-2080-8_7.


Quantitation of glucocorticoid receptor DNA-binding dynamics by single-molecule microscopy and FRAP.

Groeneweg FL, van Royen ME, Fenz S, Keizer VI, Geverts B, Prins J, de Kloet ER, Houtsmuller AB, Schmidt TS, Schaaf MJ.

PLoS One. 2014 Mar 14;9(3):e90532. doi: 10.1371/journal.pone.0090532. eCollection 2014.


Androgen receptor complexes probe DNA for recognition sequences by short random interactions.

Van Royen ME, van Cappellen WA, Geverts B, Schmidt T, Houtsmuller AB, Schaaf MJ.

J Cell Sci. 2014 Apr 1;127(Pt 7):1406-16. doi: 10.1242/jcs.135228. Epub 2014 Jan 30.


The leukemia-associated fusion protein MN1-TEL blocks TEL-specific recognition sequences.

ter Haar WM, Meester-Smoor MA, van Wely KH, Schot CC, Janssen MJ, Geverts B, Bonten J, Grosveld GC, Houtsmuller AB, Zwarthoff EC.

PLoS One. 2012;7(9):e46085. doi: 10.1371/journal.pone.0046085. Epub 2012 Sep 26.


The residence time of focal adhesion kinase (FAK) and paxillin at focal adhesions in renal epithelial cells is determined by adhesion size, strength and life cycle status.

Le Dévédec SE, Geverts B, de Bont H, Yan K, Verbeek FJ, Houtsmuller AB, van de Water B.

J Cell Sci. 2012 Oct 1;125(Pt 19):4498-506. doi: 10.1242/jcs.104273. Epub 2012 Jul 5.


Nuclear proteins: finding and binding target sites in chromatin.

van Royen ME, Zotter A, Ibrahim SM, Geverts B, Houtsmuller AB.

Chromosome Res. 2011 Jan;19(1):83-98. doi: 10.1007/s10577-010-9172-5.


Chromatin interaction of TATA-binding protein is dynamically regulated in human cells.

de Graaf P, Mousson F, Geverts B, Scheer E, Tora L, Houtsmuller AB, Timmers HT.

J Cell Sci. 2010 Aug 1;123(Pt 15):2663-71. doi: 10.1242/jcs.064097. Epub 2010 Jul 13.


A 629RKLKK633 motif in the hinge region controls the androgen receptor at multiple levels.

Tanner TM, Denayer S, Geverts B, Van Tilborgh N, Kerkhofs S, Helsen C, Spans L, Dubois V, Houtsmuller AB, Claessens F, Haelens A.

Cell Mol Life Sci. 2010 Jun;67(11):1919-27. doi: 10.1007/s00018-010-0302-1. Epub 2010 Feb 26.


Fluorescence recovery after photobleaching (FRAP) to study nuclear protein dynamics in living cells.

van Royen ME, Farla P, Mattern KA, Geverts B, Trapman J, Houtsmuller AB.

Methods Mol Biol. 2009;464:363-85. doi: 10.1007/978-1-60327-461-6_20.


Cellular concentrations of DDB2 regulate dynamic binding of DDB1 at UV-induced DNA damage.

Alekseev S, Luijsterburg MS, Pines A, Geverts B, Mari PO, Giglia-Mari G, Lans H, Houtsmuller AB, Mullenders LH, Hoeijmakers JH, Vermeulen W.

Mol Cell Biol. 2008 Dec;28(24):7402-13. doi: 10.1128/MCB.01108-08. Epub 2008 Oct 20.


Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC.

Hoogstraten D, Bergink S, Ng JM, Verbiest VH, Luijsterburg MS, Geverts B, Raams A, Dinant C, Hoeijmakers JH, Vermeulen W, Houtsmuller AB.

J Cell Sci. 2008 Sep 1;121(Pt 17):2850-9. doi: 10.1242/jcs.031708. Epub 2008 Aug 5. Erratum in: J Cell Sci. 2008 Dec 1;121(Pt 23):3991. Ng, Jessica M Y [added]. J Cell Sci. 2008 Sep 1;121(Pt 17):2972.


Human USP3 is a chromatin modifier required for S phase progression and genome stability.

Nicassio F, Corrado N, Vissers JH, Areces LB, Bergink S, Marteijn JA, Geverts B, Houtsmuller AB, Vermeulen W, Di Fiore PP, Citterio E.

Curr Biol. 2007 Nov 20;17(22):1972-7. Epub 2007 Nov 1.


UTF1 is a chromatin-associated protein involved in ES cell differentiation.

van den Boom V, Kooistra SM, Boesjes M, Geverts B, Houtsmuller AB, Monzen K, Komuro I, Essers J, Drenth-Diephuis LJ, Eggen BJ.

J Cell Biol. 2007 Sep 10;178(6):913-24. Epub 2007 Sep 4.


Dynamic in vivo interaction of DDB2 E3 ubiquitin ligase with UV-damaged DNA is independent of damage-recognition protein XPC.

Luijsterburg MS, Goedhart J, Moser J, Kool H, Geverts B, Houtsmuller AB, Mullenders LH, Vermeulen W, van Driel R.

J Cell Sci. 2007 Aug 1;120(Pt 15):2706-16. Epub 2007 Jul 17.


Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin.

Xouri G, Squire A, Dimaki M, Geverts B, Verveer PJ, Taraviras S, Nishitani H, Houtsmuller AB, Bastiaens PI, Lygerou Z.

EMBO J. 2007 Mar 7;26(5):1303-14. Epub 2007 Feb 22.


The androgen receptor ligand-binding domain stabilizes DNA binding in living cells.

Farla P, Hersmus R, Geverts B, Mari PO, Nigg AL, Dubbink HJ, Trapman J, Houtsmuller AB.

J Struct Biol. 2004 Jul;147(1):50-61.


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