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Items: 1 to 50 of 176

1.

Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity.

van Montfoort N, Camps MG, Khan S, Filippov DV, Weterings JJ, Griffith JM, Geuze HJ, van Hall T, Verbeek JS, Melief CJ, Ossendorp F.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6730-5. doi: 10.1073/pnas.0900969106. Epub 2009 Apr 3.

2.

SNX1 defines an early endosomal recycling exit for sortilin and mannose 6-phosphate receptors.

Mari M, Bujny MV, Zeuschner D, Geerts WJ, Griffith J, Petersen CM, Cullen PJ, Klumperman J, Geuze HJ.

Traffic. 2008 Mar;9(3):380-93. Epub 2007 Dec 9.

3.

Cryosectioning and immunolabeling.

Slot JW, Geuze HJ.

Nat Protoc. 2007;2(10):2480-91.

PMID:
17947990
4.

Slow endocytosis of the LDL receptor-related protein 1B: implications for a novel cytoplasmic tail conformation.

Knisely JM, Li Y, Griffith JM, Geuze HJ, Schwartz AL, Bu G.

Exp Cell Res. 2007 Sep 10;313(15):3298-307. Epub 2007 Jun 29.

5.

Formation of peroxisomes: present and past.

Tabak HF, Hoepfner D, Zand Av, Geuze HJ, Braakman I, Huynen MA.

Biochim Biophys Acta. 2006 Dec;1763(12):1647-54. Epub 2006 Sep 3. Review.

6.

The return of the peroxisome.

van der Zand A, Braakman I, Geuze HJ, Tabak HF.

J Cell Sci. 2006 Mar 15;119(Pt 6):989-94. Review.

7.

Characterization of the TGN exit signal of the human mannose 6-phosphate uncovering enzyme.

Nair P, Schaub BE, Huang K, Chen X, Murphy RF, Griffith JM, Geuze HJ, Rohrer J.

J Cell Sci. 2005 Jul 1;118(Pt 13):2949-56.

8.

3-D Structure of multilaminar lysosomes in antigen presenting cells reveals trapping of MHC II on the internal membranes.

Murk JL, Lebbink MN, Humbel BM, Geerts WJ, Griffith JM, Langenberg DM, Verreck FA, Verkleij AJ, Koster AJ, Geuze HJ, Kleijmeer MJ.

Traffic. 2004 Dec;5(12):936-45.

9.

Overall major histocompatibility complex class I expression is not downregulated in cervix cancer, as detected by immunoelectron microscopy.

van Eijkeren MA, Roovers JP, Oorschot V, Geuze HJ.

Int J Gynecol Cancer. 2004 Mar-Apr;14(2):317-21.

PMID:
15086732
10.

Mammalian GGAs act together to sort mannose 6-phosphate receptors.

Ghosh P, Griffith J, Geuze HJ, Kornfeld S.

J Cell Biol. 2003 Nov 24;163(4):755-66.

11.

Endosomal compartmentalization in three dimensions: implications for membrane fusion.

Murk JL, Humbel BM, Ziese U, Griffith JM, Posthuma G, Slot JW, Koster AJ, Verkleij AJ, Geuze HJ, Kleijmeer MJ.

Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13332-7. Epub 2003 Nov 3.

12.

Influence of aldehyde fixation on the morphology of endosomes and lysosomes: quantitative analysis and electron tomography.

Murk JL, Posthuma G, Koster AJ, Geuze HJ, Verkleij AJ, Kleijmeer MJ, Humbel BM.

J Microsc. 2003 Oct;212(Pt 1):81-90.

13.

Arabidopsis sterol endocytosis involves actin-mediated trafficking via ARA6-positive early endosomes.

Grebe M, Xu J, Möbius W, Ueda T, Nakano A, Geuze HJ, Rook MB, Scheres B.

Curr Biol. 2003 Aug 19;13(16):1378-87.

14.

Involvement of the endoplasmic reticulum in peroxisome formation.

Geuze HJ, Murk JL, Stroobants AK, Griffith JM, Kleijmeer MJ, Koster AJ, Verkleij AJ, Distel B, Tabak HF.

Mol Biol Cell. 2003 Jul;14(7):2900-7. Epub 2003 Apr 4.

15.

Peroxisomes start their life in the endoplasmic reticulum.

Tabak HF, Murk JL, Braakman I, Geuze HJ.

Traffic. 2003 Aug;4(8):512-8. Review.

16.

Recycling compartments and the internal vesicles of multivesicular bodies harbor most of the cholesterol found in the endocytic pathway.

Möbius W, van Donselaar E, Ohno-Iwashita Y, Shimada Y, Heijnen HF, Slot JW, Geuze HJ.

Traffic. 2003 Apr;4(4):222-31.

17.

Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation.

Wubbolts R, Leckie RS, Veenhuizen PT, Schwarzmann G, Möbius W, Hoernschemeyer J, Slot JW, Geuze HJ, Stoorvogel W.

J Biol Chem. 2003 Mar 28;278(13):10963-72. Epub 2003 Jan 7.

18.

MHC class II compartments in human dendritic cells undergo profound structural changes upon activation.

Barois N, de Saint-Vis B, Lebecque S, Geuze HJ, Kleijmeer MJ.

Traffic. 2002 Dec;3(12):894-905.

19.

The plasticity of multivesicular bodies and the regulation of antigen presentation.

Murk JL, Stoorvogel W, Kleijmeer MJ, Geuze HJ.

Semin Cell Dev Biol. 2002 Aug;13(4):303-11. Review.

PMID:
12243730
20.

Proteasome regulates the delivery of LDL receptor-related protein into the degradation pathway.

Melman L, Geuze HJ, Li Y, McCormick LM, Van Kerkhof P, Strous GJ, Schwartz AL, Bu G.

Mol Biol Cell. 2002 Sep;13(9):3325-35.

21.

Cooperation of GGAs and AP-1 in packaging MPRs at the trans-Golgi network.

Doray B, Ghosh P, Griffith J, Geuze HJ, Kornfeld S.

Science. 2002 Sep 6;297(5587):1700-3.

22.

The biogenesis and functions of exosomes.

Stoorvogel W, Kleijmeer MJ, Geuze HJ, Raposo G.

Traffic. 2002 May;3(5):321-30. Review.

23.

The ER to Golgi interface is the major concentration site of secretory proteins in the exocrine pancreatic cell.

Oprins A, Rabouille C, Posthuma G, Klumperman J, Geuze HJ, Slot JW.

Traffic. 2001 Nov;2(11):831-8.

24.

Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic perfringolysin O.

Möbius W, Ohno-Iwashita Y, van Donselaar EG, Oorschot VM, Shimada Y, Fujimoto T, Heijnen HF, Geuze HJ, Slot JW.

J Histochem Cytochem. 2002 Jan;50(1):43-55.

PMID:
11748293
25.

Peri-Golgi vesicles contain retrograde but not anterograde proteins consistent with the cisternal progression model of intra-Golgi transport.

Martinez-Menárguez JA, Prekeris R, Oorschot VM, Scheller R, Slot JW, Geuze HJ, Klumperman J.

J Cell Biol. 2001 Dec 24;155(7):1213-24. Epub 2001 Dec 17.

26.

Rab4 regulates formation of synaptic-like microvesicles from early endosomes in PC12 cells.

de Wit H, Lichtenstein Y, Kelly RB, Geuze HJ, Klumperman J, van der Sluijs P.

Mol Biol Cell. 2001 Nov;12(11):3703-15.

27.

Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells.

Kleijmeer M, Ramm G, Schuurhuis D, Griffith J, Rescigno M, Ricciardi-Castagnoli P, Rudensky AY, Ossendorp F, Melief CJ, Stoorvogel W, Geuze HJ.

J Cell Biol. 2001 Oct 1;155(1):53-63.

28.

Antigen loading of MHC class I molecules in the endocytic tract.

Kleijmeer MJ, Escola JM, UytdeHaag FG, Jakobson E, Griffith JM, Osterhaus AD, Stoorvogel W, Melief CJ, Rabouille C, Geuze HJ.

Traffic. 2001 Feb;2(2):124-37.

29.

The dileucine motif within the tail of MPR46 is required for sorting of the receptor in endosomes.

Tikkanen R, Obermüller S, Denzer K, Pungitore R, Geuze HJ, von Figura K, Höning S.

Traffic. 2000 Aug;1(8):631-40.

30.

Immunoelectron microscopy of antigen processing in dendritic cells.

Kleijmeer MJ, Posthuma G, Geuze HJ.

Methods Mol Med. 2001;64:387-411. doi: 10.1385/1-59259-150-7:387.

PMID:
21374277
31.

Subcellular distribution of CFTR in rat intestine supports a physiologic role for CFTR regulation by vesicle traffic.

Ameen NA, van Donselaar E, Posthuma G, de Jonge H, McLaughlin G, Geuze HJ, Marino C, Peters PJ.

Histochem Cell Biol. 2000 Sep;114(3):219-28.

PMID:
11083465
32.

Exosome: from internal vesicle of the multivesicular body to intercellular signaling device.

Denzer K, Kleijmeer MJ, Heijnen HF, Stoorvogel W, Geuze HJ.

J Cell Sci. 2000 Oct;113 Pt 19:3365-74. Review.

34.

Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface.

Denzer K, van Eijk M, Kleijmeer MJ, Jakobson E, de Groot C, Geuze HJ.

J Immunol. 2000 Aug 1;165(3):1259-65.

35.

Immature dendritic cells acquire CD8(+) cytotoxic T lymphocyte priming capacity upon activation by T helper cell-independent or -dependent stimuli.

Schuurhuis DH, Laban S, Toes RE, Ricciardi-Castagnoli P, Kleijmeer MJ, van der Voort EI, Rea D, Offringa R, Geuze HJ, Melief CJ, Ossendorp F.

J Exp Med. 2000 Jul 3;192(1):145-50.

36.

Synaptic assembly of the brain in the absence of neurotransmitter secretion.

Verhage M, Maia AS, Plomp JJ, Brussaard AB, Heeroma JH, Vermeer H, Toonen RF, Hammer RE, van den Berg TK, Missler M, Geuze HJ, Südhof TC.

Science. 2000 Feb 4;287(5454):864-9.

37.

Enzymatic reduction of disulfide bonds in lysosomes: characterization of a gamma-interferon-inducible lysosomal thiol reductase (GILT).

Arunachalam B, Phan UT, Geuze HJ, Cresswell P.

Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):745-50.

38.

Synaptic vesicles form by budding from tubular extensions of sorting endosomes in PC12 cells.

de Wit H, Lichtenstein Y, Geuze HJ, Kelly RB, van der Sluijs P, Klumperman J.

Mol Biol Cell. 1999 Dec;10(12):4163-76.

40.
41.

The FcgammaRIa (CD64) ligand binding chain triggers major histocompatibility complex class II antigen presentation independently of its associated FcR gamma-chain.

van Vugt MJ, Kleijmeer MJ, Keler T, Zeelenberg I, van Dijk MA, Leusen JH, Geuze HJ, van de Winkel JG.

Blood. 1999 Jul 15;94(2):808-17.

PMID:
10397749
42.

A future for electron microscopy in cell biology?

Geuze HJ.

Trends Cell Biol. 1999 Mar;9(3):92-3. No abstract available.

PMID:
10201073
43.

Peptide loading in the endoplasmic reticulum accelerates trafficking of peptide:MHC class II complexes in B cells.

Morkowski S, Raposo G, Geuze HJ, Rudensky AY.

J Biomed Sci. 1999 Jan;6(1):53-63.

PMID:
9933743
44.

Procollagen traverses the Golgi stack without leaving the lumen of cisternae: evidence for cisternal maturation.

Bonfanti L, Mironov AA Jr, Martínez-Menárguez JA, Martella O, Fusella A, Baldassarre M, Buccione R, Geuze HJ, Mironov AA, Luini A.

Cell. 1998 Dec 23;95(7):993-1003.

45.

The tetraspan protein CD82 is a resident of MHC class II compartments where it associates with HLA-DR, -DM, and -DO molecules.

Hammond C, Denzin LK, Pan M, Griffith JM, Geuze HJ, Cresswell P.

J Immunol. 1998 Oct 1;161(7):3282-91.

46.

Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes.

Escola JM, Kleijmeer MJ, Stoorvogel W, Griffith JM, Yoshie O, Geuze HJ.

J Biol Chem. 1998 Aug 7;273(32):20121-7.

47.

The role of endosomes and lysosomes in MHC class II functioning.

Geuze HJ.

Immunol Today. 1998 Jun;19(6):282-7. Review. No abstract available.

PMID:
9639994
48.
49.

Multivesicular bodies are an intermediate stage in the formation of platelet alpha-granules.

Heijnen HF, Debili N, Vainchencker W, Breton-Gorius J, Geuze HJ, Sixma JJ.

Blood. 1998 Apr 1;91(7):2313-25.

PMID:
9516129

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