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Items: 31

1.

Bordetella pertussis population dynamics and phylogeny in Japan after adoption of acellular pertussis vaccines.

Zomer A, Otsuka N, Hiramatsu Y, Kamachi K, Nishimura N, Ozaki T, Poolman J, Geurtsen J.

Microb Genom. 2018 May;4(5). doi: 10.1099/mgen.0.000180. Epub 2018 May 17.

2.

A unique PE_PGRS protein inhibiting host cell cytosolic defenses and sustaining full virulence of Mycobacterium marinum in multiple hosts.

Singh VK, Berry L, Bernut A, Singh S, Carrère-Kremer S, Viljoen A, Alibaud L, Majlessi L, Brosch R, Chaturvedi V, Geurtsen J, Drancourt M, Kremer L.

Cell Microbiol. 2016 Nov;18(11):1489-1507. doi: 10.1111/cmi.12606. Epub 2016 Jun 1.

PMID:
27120981
3.

Metabolic Network for the Biosynthesis of Intra- and Extracellular α-Glucans Required for Virulence of Mycobacterium tuberculosis.

Koliwer-Brandl H, Syson K, van de Weerd R, Chandra G, Appelmelk B, Alber M, Ioerger TR, Jacobs WR Jr, Geurtsen J, Bornemann S, Kalscheuer R.

PLoS Pathog. 2016 Aug 11;12(8):e1005768. doi: 10.1371/journal.ppat.1005768. eCollection 2016 Aug.

4.

Inorganic Phosphate Limitation Modulates Capsular Polysaccharide Composition in Mycobacteria.

van de Weerd R, Boot M, Maaskant J, Sparrius M, Verboom T, van Leeuwen LM, Burggraaf MJ, Paauw NJ, Dainese E, Manganelli R, Bitter W, Appelmelk BJ, Geurtsen J.

J Biol Chem. 2016 May 27;291(22):11787-99. doi: 10.1074/jbc.M116.722454. Epub 2016 Apr 4.

5.

Bordetella pertussis filamentous hemagglutinin itself does not trigger anti-inflammatory interleukin-10 production by human dendritic cells.

Villarino Romero R, Hasan S, Faé K, Holubova J, Geurtsen J, Schwarzer M, Wiertsema S, Osicka R, Poolman J, Sebo P.

Int J Med Microbiol. 2016 Jan;306(1):38-47. doi: 10.1016/j.ijmm.2015.11.003. Epub 2015 Nov 30.

PMID:
26699834
6.

A murine monoclonal antibody to glycogen: characterization of epitope-fine specificity by saturation transfer difference (STD) NMR spectroscopy and its use in mycobacterial capsular α-glucan research.

van de Weerd R, Berbís MA, Sparrius M, Maaskant JJ, Boot M, Paauw NJ, de Vries N, Boon L, Baba O, Cañada FJ, Geurtsen J, Jiménez-Barbero J, Appelmelk BJ.

Chembiochem. 2015 Apr 13;16(6):977-89. doi: 10.1002/cbic.201402713. Epub 2015 Mar 12.

PMID:
25766777
7.

A new dehydratase conferring innate resistance to thiacetazone and intra-amoebal survival of Mycobacterium smegmatis.

Carrère-Kremer S, Blaise M, Singh VK, Alibaud L, Tuaillon E, Halloum I, van de Weerd R, Guérardel Y, Drancourt M, Takiff H, Geurtsen J, Kremer L.

Mol Microbiol. 2015 Jun;96(5):1085-102. doi: 10.1111/mmi.12992. Epub 2015 Mar 28.

8.

Importance of (antibody-dependent) complement-mediated serum killing in protection against Bordetella pertussis.

Geurtsen J, Fae KC, van den Dobbelsteen GP.

Expert Rev Vaccines. 2014 Oct;13(10):1229-40. doi: 10.1586/14760584.2014.944901. Epub 2014 Aug 1. Review.

PMID:
25081731
9.

Structure and function of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo.

Romano M, van de Weerd R, Brouwer FC, Roviello GN, Lacroix R, Sparrius M, van den Brink-van Stempvoort G, Maaskant JJ, van der Sar AM, Appelmelk BJ, Geurtsen JJ, Berisio R.

Structure. 2014 May 6;22(5):719-30. doi: 10.1016/j.str.2014.01.014. Epub 2014 Apr 3.

10.

Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity.

Stoop EJ, Mishra AK, Driessen NN, van Stempvoort G, Bouchier P, Verboom T, van Leeuwen LM, Sparrius M, Raadsen SA, van Zon M, van der Wel NN, Besra GS, Geurtsen J, Bitter W, Appelmelk BJ, van der Sar AM.

Cell Microbiol. 2013 Dec;15(12):2093-108. doi: 10.1111/cmi.12175. Epub 2013 Aug 22.

11.

Differential arabinan capping of lipoarabinomannan modulates innate immune responses and impacts T helper cell differentiation.

Mishra AK, Alves JE, Krumbach K, Nigou J, Castro AG, Geurtsen J, Eggeling L, Saraiva M, Besra GS.

J Biol Chem. 2012 Dec 28;287(53):44173-83. doi: 10.1074/jbc.M112.402396. Epub 2012 Nov 9.

12.

Lipoarabinomannan mannose caps do not affect mycobacterial virulence or the induction of protective immunity in experimental animal models of infection and have minimal impact on in vitro inflammatory responses.

Afonso-Barroso A, Clark SO, Williams A, Rosa GT, Nóbrega C, Silva-Gomes S, Vale-Costa S, Ummels R, Stoker N, Movahedzadeh F, van der Ley P, Sloots A, Cot M, Appelmelk BJ, Puzo G, Nigou J, Geurtsen J, Appelberg R.

Cell Microbiol. 2013 Apr;15(4):660-74. doi: 10.1111/cmi.12065. Epub 2012 Nov 21.

PMID:
23121245
13.

Cyanovirin-N inhibits mannose-dependent Mycobacterium-C-type lectin interactions but does not protect against murine tuberculosis.

Driessen NN, Boshoff HI, Maaskant JJ, Gilissen SA, Vink S, van der Sar AM, Vandenbroucke-Grauls CM, Bewley CA, Appelmelk BJ, Geurtsen J.

J Immunol. 2012 Oct 1;189(7):3585-92. Epub 2012 Aug 31.

14.

Unexpected link between lipooligosaccharide biosynthesis and surface protein release in Mycobacterium marinum.

van der Woude AD, Sarkar D, Bhatt A, Sparrius M, Raadsen SA, Boon L, Geurtsen J, van der Sar AM, Luirink J, Houben EN, Besra GS, Bitter W.

J Biol Chem. 2012 Jun 8;287(24):20417-29. doi: 10.1074/jbc.M111.336461. Epub 2012 Apr 13.

15.

Lipoarabinomannan biosynthesis in Corynebacterineae: the interplay of two α(1→2)-mannopyranosyltransferases MptC and MptD in mannan branching.

Mishra AK, Krumbach K, Rittmann D, Appelmelk B, Pathak V, Pathak AK, Nigou J, Geurtsen J, Eggeling L, Besra GS.

Mol Microbiol. 2011 Jun;80(5):1241-59. doi: 10.1111/j.1365-2958.2011.07640.x. Epub 2011 Apr 4.

16.

Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins.

Sani M, Houben EN, Geurtsen J, Pierson J, de Punder K, van Zon M, Wever B, Piersma SR, Jiménez CR, Daffé M, Appelmelk BJ, Bitter W, van der Wel N, Peters PJ.

PLoS Pathog. 2010 Mar 5;6(3):e1000794. doi: 10.1371/journal.ppat.1000794.

17.

A truncated lipoglycan from mycobacteria with altered immunological properties.

Birch HL, Alderwick LJ, Appelmelk BJ, Maaskant J, Bhatt A, Singh A, Nigou J, Eggeling L, Geurtsen J, Besra GS.

Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2634-9. doi: 10.1073/pnas.0915082107. Epub 2010 Jan 25.

18.

Identification of mycobacterial alpha-glucan as a novel ligand for DC-SIGN: involvement of mycobacterial capsular polysaccharides in host immune modulation.

Geurtsen J, Chedammi S, Mesters J, Cot M, Driessen NN, Sambou T, Kakutani R, Ummels R, Maaskant J, Takata H, Baba O, Terashima T, Bovin N, Vandenbroucke-Grauls CM, Nigou J, Puzo G, Lemassu A, Daffé M, Appelmelk BJ.

J Immunol. 2009 Oct 15;183(8):5221-31. doi: 10.4049/jimmunol.0900768. Epub 2009 Sep 25.

19.

Role of phosphatidylinositol mannosides in the interaction between mycobacteria and DC-SIGN.

Driessen NN, Ummels R, Maaskant JJ, Gurcha SS, Besra GS, Ainge GD, Larsen DS, Painter GF, Vandenbroucke-Grauls CM, Geurtsen J, Appelmelk BJ.

Infect Immun. 2009 Oct;77(10):4538-47. doi: 10.1128/IAI.01256-08. Epub 2009 Aug 3.

20.

Identification of a novel lipopolysaccharide core biosynthesis gene cluster in Bordetella pertussis, and influence of core structure and lipid A glucosamine substitution on endotoxic activity.

Geurtsen J, Dzieciatkowska M, Steeghs L, Hamstra HJ, Boleij J, Broen K, Akkerman G, El Hassan H, Li J, Richards JC, Tommassen J, van der Ley P.

Infect Immun. 2009 Jul;77(7):2602-11. doi: 10.1128/IAI.00033-09. Epub 2009 Apr 13.

21.

Supplementation of whole-cell pertussis vaccines with lipopolysaccharide analogs: modification of vaccine-induced immune responses.

Geurtsen J, Fransen F, Vandebriel RJ, Gremmer ER, de la Fonteyne-Blankestijn LJ, Kuipers B, Tommassen J, van der Ley P.

Vaccine. 2008 Feb 13;26(7):899-906. doi: 10.1016/j.vaccine.2007.12.012. Epub 2007 Dec 31.

PMID:
18207288
22.

The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction.

Appelmelk BJ, den Dunnen J, Driessen NN, Ummels R, Pak M, Nigou J, Larrouy-Maumus G, Gurcha SS, Movahedzadeh F, Geurtsen J, Brown EJ, Eysink Smeets MM, Besra GS, Willemsen PT, Lowary TL, van Kooyk Y, Maaskant JJ, Stoker NG, van der Ley P, Puzo G, Vandenbroucke-Grauls CM, Wieland CW, van der Poll T, Geijtenbeek TB, van der Sar AM, Bitter W.

Cell Microbiol. 2008 Apr;10(4):930-44. Epub 2007 Dec 5.

PMID:
18070119
23.

A novel secondary acyl chain in the lipopolysaccharide of Bordetella pertussis required for efficient infection of human macrophages.

Geurtsen J, Angevaare E, Janssen M, Hamstra HJ, ten Hove J, de Haan A, Kuipers B, Tommassen J, van der Ley P.

J Biol Chem. 2007 Dec 28;282(52):37875-84. Epub 2007 Oct 29.

24.

Consequences of the expression of lipopolysaccharide-modifying enzymes for the efficacy and reactogenicity of whole-cell pertussis vaccines.

Geurtsen J, Vandebriel RJ, Gremmer ER, Kuipers B, Tommassen J, van der Ley P.

Microbes Infect. 2007 Jul;9(9):1096-103. Epub 2007 May 17.

PMID:
17644385
25.

Lipopolysaccharide analogs improve efficacy of acellular pertussis vaccine and reduce type I hypersensitivity in mice.

Geurtsen J, Banus HA, Gremmer ER, Ferguson H, de la Fonteyne-Blankestijn LJ, Vermeulen JP, Dormans JA, Tommassen J, van der Ley P, Mooi FR, Vandebriel RJ.

Clin Vaccine Immunol. 2007 Jul;14(7):821-9. Epub 2007 May 9.

26.

Expression of the lipopolysaccharide-modifying enzymes PagP and PagL modulates the endotoxic activity of Bordetella pertussis.

Geurtsen J, Steeghs L, Hamstra HJ, Ten Hove J, de Haan A, Kuipers B, Tommassen J, van der Ley P.

Infect Immun. 2006 Oct;74(10):5574-85.

27.

Crystal structure and catalytic mechanism of the LPS 3-O-deacylase PagL from Pseudomonas aeruginosa.

Rutten L, Geurtsen J, Lambert W, Smolenaers JJ, Bonvin AM, de Haan A, van der Ley P, Egmond MR, Gros P, Tommassen J.

Proc Natl Acad Sci U S A. 2006 May 2;103(18):7071-6. Epub 2006 Apr 21.

28.

Dissemination of lipid A deacylases (pagL) among gram-negative bacteria: identification of active-site histidine and serine residues.

Geurtsen J, Steeghs L, Hove JT, van der Ley P, Tommassen J.

J Biol Chem. 2005 Mar 4;280(9):8248-59. Epub 2004 Dec 20.

29.

Lipopolysaccharide transport to the bacterial outer membrane in spheroplasts.

Tefsen B, Geurtsen J, Beckers F, Tommassen J, de Cock H.

J Biol Chem. 2005 Feb 11;280(6):4504-9. Epub 2004 Dec 2.

30.

Identification of an outer membrane protein required for the transport of lipopolysaccharide to the bacterial cell surface.

Bos MP, Tefsen B, Geurtsen J, Tommassen J.

Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9417-22. Epub 2004 Jun 10.

31.

Role of a highly conserved bacterial protein in outer membrane protein assembly.

Voulhoux R, Bos MP, Geurtsen J, Mols M, Tommassen J.

Science. 2003 Jan 10;299(5604):262-5.

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