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Atherosclerosis: cell biology and lipoproteins.

Getz GS, Reardon CA.

Curr Opin Lipidol. 2019 Dec 6. doi: 10.1097/MOL.0000000000000655. [Epub ahead of print] No abstract available.


Proceedings of the Ninth HDL (High-Density Lipoprotein) Workshop: Focus on Cardiovascular Disease.

Rodriguez A, Trigatti BL, Mineo C, Knaack D, Wilkins JT, Sahoo D, Asztalos BF, Mora S, Cuchel M, Pownall HJ, Rosales C, Bernatchez P, Ribeiro Martins da Silva A, Getz GS, Barber JL, Shearer GC, Zivkovic AM, Tietge UJF, Sacks FM, Connelly MA, Oda MN, Davidson WS, Sorci-Thomas MG, Vaisar T, Ruotolo G, Vickers KC, Martel C.

Arterioscler Thromb Vasc Biol. 2019 Dec;39(12):2457-2467. doi: 10.1161/ATVBAHA.119.313340. Epub 2019 Oct 10.


Invariant Natural Killer T-Cells and Total CD1d Restricted Cells Differentially Influence Lipid Metabolism and Atherosclerosis in Low Density Receptor Deficient Mice.

VanderLaan PA, Reardon CA, Cabana VG, Wang CR, Getz GS.

Int J Mol Sci. 2019 Sep 14;20(18). pii: E4566. doi: 10.3390/ijms20184566.


Apoproteins E, A-I, and SAA in Macrophage Pathobiology Related to Atherogenesis.

Getz GS, Reardon CA.

Front Pharmacol. 2019 May 21;10:536. doi: 10.3389/fphar.2019.00536. eCollection 2019. Review.


Apoprotein E and Reverse Cholesterol Transport.

Getz GS, Reardon CA.

Int J Mol Sci. 2018 Nov 6;19(11). pii: E3479. doi: 10.3390/ijms19113479. Review.


Diet, Microbes, and Murine Atherosclerosis.

Getz GS, Reardon CA.

Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):2269-2271. doi: 10.1161/ATVBAHA.118.311513. No abstract available.


Hypercholesterolemia-Induced Loss of Flow-Induced Vasodilation and Lesion Formation in Apolipoprotein E-Deficient Mice Critically Depend on Inwardly Rectifying K+ Channels.

Fancher IS, Ahn SJ, Adamos C, Osborn C, Oh MJ, Fang Y, Reardon CA, Getz GS, Phillips SA, Levitan I.

J Am Heart Assoc. 2018 Mar 3;7(5). pii: e007430. doi: 10.1161/JAHA.117.007430.


Lipid Transfer Proteins: Introduction to the Thematic Review Series.

Getz GS.

J Lipid Res. 2018 May;59(5):745-748. doi: 10.1194/jlr.R084020. Epub 2018 Feb 26. No abstract available.


Deficiency of Invariant Natural Killer T Cells Does Not Protect Against Obesity but Exacerbates Atherosclerosis in Ldlr-/- Mice.

Subramanian S, Goodspeed L, Wang S, Ding Y, O'Brien KD, Getz GS, Chait A, Reardon CA.

Int J Mol Sci. 2018 Feb 8;19(2). pii: E510. doi: 10.3390/ijms19020510.


T Cells in Atherosclerosis in Ldlr-/- and Apoe-/- Mice.

Getz GS, Reardon CA.

J Immunol Sci. 2018;2(3):69-76. doi: 10.29245/2578-3009/2018/3.1144. Epub 2018 Jun 27.


Plasminogen promotes cholesterol efflux by the ABCA1 pathway.

Pamir N, Hutchins PM, Ronsein GE, Wei H, Tang C, Das R, Vaisar T, Plow E, Schuster V, Koschinsky ML, Reardon CA, Weinberg R, Dichek DA, Marcovina S, Getz GS, Heinecke JW.

JCI Insight. 2017 Aug 3;2(15). pii: 92176. doi: 10.1172/jci.insight.92176. eCollection 2017 Aug 3.


Genetic control of apoprotein A-I and atheroprotection: some insights from inbred strains of mice.

Getz GS, Reardon CA.

Curr Opin Lipidol. 2017 Oct;28(5):403-407. doi: 10.1097/MOL.0000000000000442. Review.


Natural killer T cells in atherosclerosis.

Getz GS, Reardon CA.

Nat Rev Cardiol. 2017 May;14(5):304-314. doi: 10.1038/nrcardio.2017.2. Epub 2017 Jan 27. Review.


Serum amyloid A and atherosclerosis.

Getz GS, Krishack PA, Reardon CA.

Curr Opin Lipidol. 2016 Oct;27(5):531-5. doi: 10.1097/MOL.0000000000000331. Review.


Do the Apoe-/- and Ldlr-/- Mice Yield the Same Insight on Atherogenesis?

Getz GS, Reardon CA.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1734-41. doi: 10.1161/ATVBAHA.116.306874. Epub 2016 Jul 7. Review.


Serum amyloid A regulates monopoiesis in hyperlipidemic Ldlr(-/-) mice.

Krishack PA, Sontag TJ, Getz GS, Reardon CA.

FEBS Lett. 2016 Aug;590(16):2650-60. doi: 10.1002/1873-3468.12269. Epub 2016 Jul 8.


The western-type diet induces anti-HMGB1 autoimmunity in Apoe(-/-) mice.

Pan Y, Ke H, Yan Z, Geng Y, Asner N, Palani S, Munirathinam G, Dasari S, Nitiss KC, Bliss S, Patel P, Shen H, Reardon CA, Getz GS, Chen A, Zheng G.

Atherosclerosis. 2016 Aug;251:31-38. doi: 10.1016/j.atherosclerosis.2016.05.027. Epub 2016 May 19.


Enzymatically Modified Low-Density Lipoprotein Promotes Foam Cell Formation in Smooth Muscle Cells via Macropinocytosis and Enhances Receptor-Mediated Uptake of Oxidized Low-Density Lipoprotein.

Chellan B, Reardon CA, Getz GS, Hofmann Bowman MA.

Arterioscler Thromb Vasc Biol. 2016 Jun;36(6):1101-13. doi: 10.1161/ATVBAHA.116.307306. Epub 2016 Apr 14.


ApoE knockout and knockin mice: the history of their contribution to the understanding of atherogenesis.

Getz GS, Reardon CA.

J Lipid Res. 2016 May;57(5):758-66. doi: 10.1194/jlr.R067249. Epub 2016 Mar 25.


Proteomic analysis of HDL from inbred mouse strains implicates APOE associated with HDL in reduced cholesterol efflux capacity via the ABCA1 pathway.

Pamir N, Hutchins P, Ronsein G, Vaisar T, Reardon CA, Getz GS, Lusis AJ, Heinecke JW.

J Lipid Res. 2016 Feb;57(2):246-57. doi: 10.1194/jlr.M063701. Epub 2015 Dec 15.


Use of Mouse Models in Atherosclerosis Research.

Getz GS, Reardon CA.

Methods Mol Biol. 2015;1339:1-16. doi: 10.1007/978-1-4939-2929-0_1. Review.


Atherogenic lipids and macrophage subsets.

Getz GS, Reardon CA.

Curr Opin Lipidol. 2015 Oct;26(5):357-61. doi: 10.1097/MOL.0000000000000217. Review.


Serum Amyloid A Facilitates Early Lesion Development in Ldlr-/- Mice.

Krishack PA, Bhanvadia CV, Lukens J, Sontag TJ, De Beer MC, Getz GS, Reardon CA.

J Am Heart Assoc. 2015 Jul 17;4(7). pii: e001858. doi: 10.1161/JAHA.115.001858.


Inhibition of atherosclerosis-promoting microRNAs via targeted polyelectrolyte complex micelles.

Kuo CH, Leon L, Chung EJ, Huang RT, Sontag TJ, Reardon CA, Getz GS, Tirrell M, Fang Y.

J Mater Chem B. 2014 Dec 14;2(46):8142-8153.


Alginic acid cell entrapment: a novel method for measuring in vivo macrophage cholesterol homeostasis.

Sontag TJ, Chellan B, Bhanvadia CV, Getz GS, Reardon CA.

J Lipid Res. 2015 Feb;56(2):470-83. doi: 10.1194/jlr.D052985. Epub 2014 Dec 1.


Selective suppression of adipose tissue apoE expression impacts systemic metabolic phenotype and adipose tissue inflammation.

Huang ZH, Reardon CA, Getz GS, Maeda N, Mazzone T.

J Lipid Res. 2015 Feb;56(2):215-26. doi: 10.1194/jlr.M050567. Epub 2014 Nov 24.


The apolipoprotein-AI mimetic peptide L4F at a modest dose does not attenuate weight gain, inflammation, or atherosclerosis in LDLR-null mice.

Averill MM, Kim EJ, Goodspeed L, Wang S, Subramanian S, Den Hartigh LJ, Tang C, Ding Y, Reardon CA, Getz GS, Chait A.

PLoS One. 2014 Oct 6;9(10):e109252. doi: 10.1371/journal.pone.0109252. eCollection 2014.


Mimetic peptides of human apoA-I helix 10 get together to lower lipids and ameliorate atherosclerosis: is the action in the gut?

Wool GD, Reardon CA, Getz GS.

J Lipid Res. 2014 Oct;55(10):1983-5. doi: 10.1194/jlr.E053538. Epub 2014 Aug 1. No abstract available.


Cutting edge: Dexamethasone potentiates the responses of both regulatory T cells and B-1 cells to antigen immunization in the ApoE(-/-) mouse model of atherosclerosis.

Chen A, Geng Y, Ke H, Constant L, Yan Z, Pan Y, Lee P, Tan I, Williams K, George S, Munirathinam G, Reardon CA, Getz GS, Wang B, Zheng G.

J Immunol. 2014 Jul 1;193(1):35-9. doi: 10.4049/jimmunol.1302469. Epub 2014 Jun 4.


Myeloperoxidase-mediated dysfunctional high-density lipoprotein.

Getz GS, Reardon CA.

Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):695-6. doi: 10.1161/ATVBAHA.114.303282. No abstract available.


PCSK9 in South African variants of familial hypercholesterolemia.

Getz GS.

J Am Coll Cardiol. 2014 Jun 10;63(22):2374-5. doi: 10.1016/j.jacc.2014.01.059. Epub 2014 Mar 12. No abstract available.


The structure/function of apoprotein A-I mimetic peptides: an update.

Getz GS, Reardon CA.

Curr Opin Endocrinol Diabetes Obes. 2014 Apr;21(2):129-33. doi: 10.1097/MED.0000000000000045. Review.


Apolipoprotein A-I protection against atherosclerosis is dependent on genetic background.

Sontag TJ, Krishack PA, Lukens JR, Bhanvadia CV, Getz GS, Reardon CA.

Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):262-9. doi: 10.1161/ATVBAHA.113.302831. Epub 2013 Dec 12.


Increased levels of invariant natural killer T lymphocytes worsen metabolic abnormalities and atherosclerosis in obese mice.

Subramanian S, Turner MS, Ding Y, Goodspeed L, Wang S, Buckner JH, O'Brien K, Getz GS, Reardon CA, Chait A.

J Lipid Res. 2013 Oct;54(10):2831-41. doi: 10.1194/jlr.M041020. Epub 2013 Aug 6.


Differing rates of cholesterol absorption among inbred mouse strains yield differing levels of HDL-cholesterol.

Sontag TJ, Chellan B, Getz GS, Reardon CA.

J Lipid Res. 2013 Sep;54(9):2515-24. doi: 10.1194/jlr.M040055. Epub 2013 Jun 27.


ApoA-I mimetics: tomatoes to the rescue.

Getz GS, Reardon CA.

J Lipid Res. 2013 Apr;54(4):878-80. doi: 10.1194/jlr.E037572. Epub 2013 Mar 7. No abstract available.


LIGHT/TNFSR14 can regulate hepatic lipase expression by hepatocytes independent of T cells and Kupffer cells.

Chellan B, Koroleva EP, Sontag TJ, Tumanov AV, Fu YX, Getz GS, Reardon CA.

PLoS One. 2013;8(1):e54719. doi: 10.1371/journal.pone.0054719. Epub 2013 Jan 23.


ApoE derived from adipose tissue does not suppress atherosclerosis or correct hyperlipidemia in apoE knockout mice.

Huang ZH, Reardon CA, Subbaiah PV, Getz GS, Mazzone T.

J Lipid Res. 2013 Jan;54(1):202-13. doi: 10.1194/jlr.M031906. Epub 2012 Oct 15.


Dexamethasone promotes tolerance in vivo by enriching CD11clo CD40lo tolerogenic macrophages.

Zheng G, Zhong S, Geng Y, Munirathinam G, Cha I, Reardon C, Getz GS, van Rooijen N, Kang Y, Wang B, Chen A.

Eur J Immunol. 2013 Jan;43(1):219-27. doi: 10.1002/eji.201242468. Epub 2012 Nov 7.


Calpain inhibition as a potential treatment of Alzheimer's disease.

Getz GS.

Am J Pathol. 2012 Aug;181(2):388-91. doi: 10.1016/j.ajpath.2012.04.027. Epub 2012 Jun 22. No abstract available.


Vitamin D receptor signaling inhibits atherosclerosis in mice.

Szeto FL, Reardon CA, Yoon D, Wang Y, Wong KE, Chen Y, Kong J, Liu SQ, Thadhani R, Getz GS, Li YC.

Mol Endocrinol. 2012 Jul;26(7):1091-101. doi: 10.1210/me.2011-1329. Epub 2012 May 25.


Sailing to Byzantium: Eugene P. Kennedy (1919-2011).

Getz GS.

FASEB J. 2012 May;26(5):1771-3. doi: 10.1096/fj.12-0502ufm. No abstract available.


Naturally occurring variant of mouse apolipoprotein A-I alters the lipid and HDL association properties of the protein.

Sontag TJ, Carnemolla R, Vaisar T, Reardon CA, Getz GS.

J Lipid Res. 2012 May;53(5):951-63. doi: 10.1194/jlr.M021154. Epub 2012 Mar 8.


Animal models of atherosclerosis.

Getz GS, Reardon CA.

Arterioscler Thromb Vasc Biol. 2012 May;32(5):1104-15. doi: 10.1161/ATVBAHA.111.237693. Epub 2012 Mar 1. Review.


Preferential interactions between ApoE-containing lipoproteins and Aβ revealed by a detection method that combines size exclusion chromatography with non-reducing gel-shift.

LaDu MJ, Munson GW, Jungbauer L, Getz GS, Reardon CA, Tai LM, Yu C.

Biochim Biophys Acta. 2012 Feb;1821(2):295-302. doi: 10.1016/j.bbalip.2011.11.005. Epub 2011 Nov 23.


Atherosclerosis: beyond cholesterol.

Getz GS, Reardon CA.

Curr Opin Lipidol. 2011 Dec;22(6):507-8. doi: 10.1097/MOL.0b013e32834d179e. No abstract available.


Apolipoprotein A-I and A-I mimetic peptides: a role in atherosclerosis.

Getz GS, Reardon CA.

J Inflamm Res. 2011;4:83-92. doi: 10.2147/JIR.S12983. Epub 2011 Jun 2.


Human oxidation-specific antibodies reduce foam cell formation and atherosclerosis progression.

Tsimikas S, Miyanohara A, Hartvigsen K, Merki E, Shaw PX, Chou MY, Pattison J, Torzewski M, Sollors J, Friedmann T, Lai NC, Hammond HK, Getz GS, Reardon CA, Li AC, Banka CL, Witztum JL.

J Am Coll Cardiol. 2011 Oct 11;58(16):1715-27. doi: 10.1016/j.jacc.2011.07.017.


Natural killer T cells in lipoprotein metabolism and atherosclerosis.

Getz GS, Vanderlaan PA, Reardon CA.

Thromb Haemost. 2011 Nov;106(5):814-9. doi: 10.1160/TH11-05-0336. Epub 2011 Sep 22. Review.

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