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Items: 1 to 50 of 67

1.

IFN-γ enhances cell-mediated cytotoxicity against keratinocytes via JAK2/STAT1 in lichen planus.

Shao S, Tsoi LC, Sarkar MK, Xing X, Xue K, Uppala R, Berthier CC, Zeng C, Patrick M, Billi AC, Fullmer J, Beamer MA, Perez-White B, Getsios S, Schuler A, Voorhees JJ, Choi S, Harms P, Kahlenberg JM, Gudjonsson JE.

Sci Transl Med. 2019 Sep 25;11(511). pii: eaav7561. doi: 10.1126/scitranslmed.aav7561.

PMID:
31554739
2.

Biotin Identification Proteomics in Three-Dimensional Organotypic Human Skin Cultures.

Cable CJ, Kaplan N, Getsios S, Thomas PM, Perez White BE.

Methods Mol Biol. 2019 May 24. doi: 10.1007/7651_2019_239. [Epub ahead of print]

PMID:
31123999
3.

Atopic Dermatitis Is an IL-13-Dominant Disease with Greater Molecular Heterogeneity Compared to Psoriasis.

Tsoi LC, Rodriguez E, Degenhardt F, Baurecht H, Wehkamp U, Volks N, Szymczak S, Swindell WR, Sarkar MK, Raja K, Shao S, Patrick M, Gao Y, Uppala R, Perez White BE, Getsios S, Harms PW, Maverakis E, Elder JT, Franke A, Gudjonsson JE, Weidinger S.

J Invest Dermatol. 2019 Jul;139(7):1480-1489. doi: 10.1016/j.jid.2018.12.018. Epub 2019 Jan 11.

PMID:
30641038
4.

Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa.

Sarkar MK, Hile GA, Tsoi LC, Xing X, Liu J, Liang Y, Berthier CC, Swindell WR, Patrick MT, Shao S, Tsou PS, Uppala R, Beamer MA, Srivastava A, Bielas SL, Harms PW, Getsios S, Elder JT, Voorhees JJ, Gudjonsson JE, Kahlenberg JM.

Ann Rheum Dis. 2018 Nov;77(11):1653-1664. doi: 10.1136/annrheumdis-2018-213197. Epub 2018 Jul 18.

5.

EphA2 Transmembrane Domain Is Uniquely Required for Keratinocyte Migration by Regulating Ephrin-A1 Levels.

Ventrella R, Kaplan N, Hoover P, Perez White BE, Lavker RM, Getsios S.

J Invest Dermatol. 2018 Oct;138(10):2133-2143. doi: 10.1016/j.jid.2018.04.011. Epub 2018 Apr 26.

6.

EphA2/Ephrin-A1 Mediate Corneal Epithelial Cell Compartmentalization via ADAM10 Regulation of EGFR Signaling.

Kaplan N, Ventrella R, Peng H, Pal-Ghosh S, Arvanitis C, Rappoport JZ, Mitchell BJ, Stepp MA, Lavker RM, Getsios S.

Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):393-406. doi: 10.1167/iovs.17-22941.

7.

Transcriptional determinants of individualized inflammatory responses at anatomically separate sites.

Tsoi LC, Yang J, Liang Y, Sarkar MK, Xing X, Beamer MA, Aphale A, Raja K, Kozlow JH, Getsios S, Voorhees JJ, Kahlenberg JM, Elder JT, Gudjonsson JE.

J Allergy Clin Immunol. 2018 Feb;141(2):805-808. doi: 10.1016/j.jaci.2017.07.054. Epub 2017 Oct 13. No abstract available.

8.

Development of a novel human recellularized endometrium that responds to a 28-day hormone treatment.

Olalekan SA, Burdette JE, Getsios S, Woodruff TK, Kim JJ.

Biol Reprod. 2017 May 1;96(5):971-981. doi: 10.1093/biolre/iox039.

9.

Act1: A Psoriasis Susceptibility Gene Playing its Part in Keratinocytes.

Hobbs RP, Smith SH, Getsios S.

J Invest Dermatol. 2017 Jul;137(7):1410-1412. doi: 10.1016/j.jid.2017.01.023. Epub 2017 Apr 5. Review.

10.

A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle.

Xiao S, Coppeta JR, Rogers HB, Isenberg BC, Zhu J, Olalekan SA, McKinnon KE, Dokic D, Rashedi AS, Haisenleder DJ, Malpani SS, Arnold-Murray CA, Chen K, Jiang M, Bai L, Nguyen CT, Zhang J, Laronda MM, Hope TJ, Maniar KP, Pavone ME, Avram MJ, Sefton EC, Getsios S, Burdette JE, Kim JJ, Borenstein JT, Woodruff TK.

Nat Commun. 2017 Mar 28;8:14584. doi: 10.1038/ncomms14584.

11.

Asymmetry at cell-cell interfaces direct cell sorting, boundary formation, and tissue morphogenesis.

Ventrella R, Kaplan N, Getsios S.

Exp Cell Res. 2017 Sep 1;358(1):58-64. doi: 10.1016/j.yexcr.2017.03.024. Epub 2017 Mar 18. Review.

12.

Endogenous Glucocorticoid Deficiency in Psoriasis Promotes Inflammation and Abnormal Differentiation.

Sarkar MK, Kaplan N, Tsoi LC, Xing X, Liang Y, Swindell WR, Hoover P, Aravind M, Baida G, Clark M, Voorhees JJ, Nair RP, Elder JT, Budunova I, Getsios S, Gudjonsson JE.

J Invest Dermatol. 2017 Jul;137(7):1474-1483. doi: 10.1016/j.jid.2017.02.972. Epub 2017 Mar 1. Erratum in: J Invest Dermatol. 2017 Dec;137(12):2665.

13.

EphA2 proteomics in human keratinocytes reveals a novel association with afadin and epidermal tight junctions.

Perez White BE, Ventrella R, Kaplan N, Cable CJ, Thomas PM, Getsios S.

J Cell Sci. 2017 Jan 1;130(1):111-118. doi: 10.1242/jcs.188169. Epub 2016 Nov 4.

14.

In Vitro Model of the Epidermis: Connecting Protein Function to 3D Structure.

Arnette C, Koetsier JL, Hoover P, Getsios S, Green KJ.

Methods Enzymol. 2016;569:287-308. doi: 10.1016/bs.mie.2015.07.015. Epub 2015 Aug 20. Review.

15.

Mind the Gap: Sex Bias in Basic Skin Research.

Kong BY, Haugh IM, Schlosser BJ, Getsios S, Paller AS.

J Invest Dermatol. 2016 Jan;136(1):12-14. doi: 10.1038/JID.2015.298.

16.

Junctions in human health and inherited disease.

Getsios S, Kelsell DP, Forge A.

Cell Tissue Res. 2015 Jun;360(3):435-8. doi: 10.1007/s00441-015-2171-2. Epub 2015 Apr 11. No abstract available.

17.

Desmosome regulation and signaling in disease.

Broussard JA, Getsios S, Green KJ.

Cell Tissue Res. 2015 Jun;360(3):501-12. doi: 10.1007/s00441-015-2136-5. Epub 2015 Feb 19. Review.

18.

microRNA-103/107 Family Regulates Multiple Epithelial Stem Cell Characteristics.

Peng H, Park JK, Katsnelson J, Kaplan N, Yang W, Getsios S, Lavker RM.

Stem Cells. 2015 May;33(5):1642-56. doi: 10.1002/stem.1962.

19.

Eph receptor and ephrin function in breast, gut, and skin epithelia.

Perez White BE, Getsios S.

Cell Adh Migr. 2014;8(4):327-38. doi: 10.4161/19336918.2014.970012. Review.

20.

FIH-1 disrupts an LRRK1/EGFR complex to positively regulate keratinocyte migration.

Peng H, Kaplan N, Yang W, Getsios S, Lavker RM.

Am J Pathol. 2014 Dec;184(12):3262-71. doi: 10.1016/j.ajpath.2014.08.014. Epub 2014 Nov 22.

21.

Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer.

Brooks YS, Ostano P, Jo SH, Dai J, Getsios S, Dziunycz P, Hofbauer GF, Cerveny K, Chiorino G, Lefort K, Dotto GP.

J Clin Invest. 2014 May;124(5):2260-76. doi: 10.1172/JCI72718. Epub 2014 Apr 17.

22.

FibronectinEDA promotes chronic cutaneous fibrosis through Toll-like receptor signaling.

Bhattacharyya S, Tamaki Z, Wang W, Hinchcliff M, Hoover P, Getsios S, White ES, Varga J.

Sci Transl Med. 2014 Apr 16;6(232):232ra50. doi: 10.1126/scitranslmed.3008264.

23.

iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier function.

Brooke MA, Etheridge SL, Kaplan N, Simpson C, O'Toole EA, Ishida-Yamamoto A, Marches O, Getsios S, Kelsell DP.

Hum Mol Genet. 2014 Aug 1;23(15):4064-76. doi: 10.1093/hmg/ddu120. Epub 2014 Mar 18.

24.

The retinoid-related orphan receptor RORα promotes keratinocyte differentiation via FOXN1.

Dai J, Brooks Y, Lefort K, Getsios S, Dotto GP.

PLoS One. 2013 Jul 29;8(7):e70392. doi: 10.1371/journal.pone.0070392. Print 2013.

25.

Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development.

Hamanaka RB, Glasauer A, Hoover P, Yang S, Blatt H, Mullen AR, Getsios S, Gottardi CJ, DeBerardinis RJ, Lavker RM, Chandel NS.

Sci Signal. 2013 Feb 5;6(261):ra8. doi: 10.1126/scisignal.2003638.

26.

Alteration of the EphA2/Ephrin-A signaling axis in psoriatic epidermis.

Gordon K, Kochkodan JJ, Blatt H, Lin SY, Kaplan N, Johnston A, Swindell WR, Hoover P, Schlosser BJ, Elder JT, Gudjonsson JE, Getsios S.

J Invest Dermatol. 2013 Mar;133(3):712-722. doi: 10.1038/jid.2012.391. Epub 2012 Nov 29.

27.

p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome.

Ferone G, Mollo MR, Thomason HA, Antonini D, Zhou H, Ambrosio R, De Rosa L, Salvatore D, Getsios S, van Bokhoven H, Dixon J, Missero C.

Hum Mol Genet. 2013 Feb 1;22(3):531-43. doi: 10.1093/hmg/dds464. Epub 2012 Oct 29.

28.

microRNA-31/factor-inhibiting hypoxia-inducible factor 1 nexus regulates keratinocyte differentiation.

Peng H, Kaplan N, Hamanaka RB, Katsnelson J, Blatt H, Yang W, Hao L, Bryar PJ, Johnson RS, Getsios S, Chandel NS, Lavker RM.

Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14030-4. doi: 10.1073/pnas.1111292109. Epub 2012 Aug 13.

29.

EphA2/Ephrin-A1 signaling complexes restrict corneal epithelial cell migration.

Kaplan N, Fatima A, Peng H, Bryar PJ, Lavker RM, Getsios S.

Invest Ophthalmol Vis Sci. 2012 Feb 23;53(2):936-45. doi: 10.1167/iovs.11-8685. Print 2012 Feb.

30.

Eph/ephrin signaling in epidermal differentiation and disease.

Lin S, Wang B, Getsios S.

Semin Cell Dev Biol. 2012 Feb;23(1):92-101. doi: 10.1016/j.semcdb.2011.10.017. Epub 2011 Oct 21. Review.

31.

Keratinocyte expression of calcitonin gene-related peptide β: implications for neuropathic and inflammatory pain mechanisms.

Hou Q, Barr T, Gee L, Vickers J, Wymer J, Borsani E, Rodella L, Getsios S, Burdo T, Eisenberg E, Guha U, Lavker R, Kessler J, Chittur S, Fiorino D, Rice F, Albrecht P.

Pain. 2011 Sep;152(9):2036-51. doi: 10.1016/j.pain.2011.04.033. Epub 2011 Jun 17.

32.

Plakoglobin rescues adhesive defects induced by ectodomain truncation of the desmosomal cadherin desmoglein 1: implications for exfoliative toxin-mediated skin blistering.

Simpson CL, Kojima S, Cooper-Whitehair V, Getsios S, Green KJ.

Am J Pathol. 2010 Dec;177(6):2921-37. doi: 10.2353/ajpath.2010.100397. Epub 2010 Nov 12.

33.

Ligand targeting of EphA2 enhances keratinocyte adhesion and differentiation via desmoglein 1.

Lin S, Gordon K, Kaplan N, Getsios S.

Mol Biol Cell. 2010 Nov 15;21(22):3902-14. doi: 10.1091/mbc.E10-03-0242. Epub 2010 Sep 22.

34.

Insights from a desmoplakin mutation identified in lethal acantholytic epidermolysis bullosa.

Hobbs RP, Han SY, van der Zwaag PA, Bolling MC, Jongbloed JD, Jonkman MF, Getsios S, Paller AS, Green KJ.

J Invest Dermatol. 2010 Nov;130(11):2680-3. doi: 10.1038/jid.2010.189. Epub 2010 Jul 8. No abstract available.

35.

From cell signaling to novel therapeutic concepts: international pemphigus meeting on advances in pemphigus research and therapy.

Getsios S, Waschke J, Borradori L, Hertl M, Müller EJ.

J Invest Dermatol. 2010 Jul;130(7):1764-8. doi: 10.1038/jid.2010.111. No abstract available.

36.

MicroRNA-205 promotes keratinocyte migration via the lipid phosphatase SHIP2.

Yu J, Peng H, Ruan Q, Fatima A, Getsios S, Lavker RM.

FASEB J. 2010 Oct;24(10):3950-9. doi: 10.1096/fj.10-157404. Epub 2010 Jun 7.

37.

Intercellular junction assembly, dynamics, and homeostasis.

Green KJ, Getsios S, Troyanovsky S, Godsel LM.

Cold Spring Harb Perspect Biol. 2010 Feb;2(2):a000125. doi: 10.1101/cshperspect.a000125. Review.

38.

RNA interference in keratinocytes and an organotypic model of human epidermis.

Simpson CL, Kojima S, Getsios S.

Methods Mol Biol. 2010;585:127-46. doi: 10.1007/978-1-60761-380-0_10.

PMID:
19908001
39.

Desmoglein 1-dependent suppression of EGFR signaling promotes epidermal differentiation and morphogenesis.

Getsios S, Simpson CL, Kojima S, Harmon R, Sheu LJ, Dusek RL, Cornwell M, Green KJ.

J Cell Biol. 2009 Jun 29;185(7):1243-58. doi: 10.1083/jcb.200809044. Epub 2009 Jun 22.

40.

MicroRNA-184 antagonizes microRNA-205 to maintain SHIP2 levels in epithelia.

Yu J, Ryan DG, Getsios S, Oliveira-Fernandes M, Fatima A, Lavker RM.

Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19300-5. doi: 10.1073/pnas.0803992105. Epub 2008 Nov 25.

41.

EGFR and ADAMs cooperate to regulate shedding and endocytic trafficking of the desmosomal cadherin desmoglein 2.

Klessner JL, Desai BV, Amargo EV, Getsios S, Green KJ.

Mol Biol Cell. 2009 Jan;20(1):328-37. doi: 10.1091/mbc.E08-04-0356. Epub 2008 Nov 5.

42.

Enhancement of UVB-induced apoptosis by apigenin in human keratinocytes and organotypic keratinocyte cultures.

Abu-Yousif AO, Smith KA, Getsios S, Green KJ, Van Dross RT, Pelling JC.

Cancer Res. 2008 Apr 15;68(8):3057-65. doi: 10.1158/0008-5472.CAN-07-2763.

43.

Plakoglobin deficiency protects keratinocytes from apoptosis.

Dusek RL, Godsel LM, Chen F, Strohecker AM, Getsios S, Harmon R, Müller EJ, Caldelari R, Cryns VL, Green KJ.

J Invest Dermatol. 2007 Apr;127(4):792-801. Epub 2006 Nov 16.

44.

The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes.

Dusek RL, Getsios S, Chen F, Park JK, Amargo EV, Cryns VL, Green KJ.

J Biol Chem. 2006 Feb 10;281(6):3614-24. Epub 2005 Nov 14.

45.

Mechanisms of plakoglobin-dependent adhesion: desmosome-specific functions in assembly and regulation by epidermal growth factor receptor.

Yin T, Getsios S, Caldelari R, Godsel LM, Kowalczyk AP, Müller EJ, Green KJ.

J Biol Chem. 2005 Dec 2;280(48):40355-63. Epub 2005 Sep 23.

46.

Plakoglobin suppresses keratinocyte motility through both cell-cell adhesion-dependent and -independent mechanisms.

Yin T, Getsios S, Caldelari R, Kowalczyk AP, Müller EJ, Jones JC, Green KJ.

Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5420-5. Epub 2005 Apr 1.

47.

Coordinated expression of desmoglein 1 and desmocollin 1 regulates intercellular adhesion.

Getsios S, Amargo EV, Dusek RL, Ishii K, Sheu L, Godsel LM, Green KJ.

Differentiation. 2004 Oct;72(8):419-33.

PMID:
15606501
48.

Epidermal growth factor receptor inhibition promotes desmosome assembly and strengthens intercellular adhesion in squamous cell carcinoma cells.

Lorch JH, Klessner J, Park JK, Getsios S, Wu YL, Stack MS, Green KJ.

J Biol Chem. 2004 Aug 27;279(35):37191-200. Epub 2004 Jun 16.

49.

Working out the strength and flexibility of desmosomes.

Getsios S, Huen AC, Green KJ.

Nat Rev Mol Cell Biol. 2004 Apr;5(4):271-81. Review. No abstract available.

PMID:
15071552
50.

The molecular composition and function of desmosomes.

Godsel LM, Getsios S, Huen AC, Green KJ.

Handb Exp Pharmacol. 2004;(165):137-93. doi: 10.1007/978-3-540-68170-0_6.

PMID:
20455093

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