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Items: 1 to 50 of 100

1.

Lobe IB of the ATPase domain of Kar2p/BiP interacts with Ire1p to negatively regulate the unfolded protein response in Saccharomyces cerevisiae.

Todd-Corlett A, Jones E, Seghers C, Gething MJ.

J Mol Biol. 2007 Mar 30;367(3):770-87. Epub 2007 Jan 9.

PMID:
17276461
2.

SCFCdc4-mediated degradation of the Hac1p transcription factor regulates the unfolded protein response in Saccharomyces cerevisiae.

Pal B, Chan NC, Helfenbaum L, Tan K, Tansey WP, Gething MJ.

Mol Biol Cell. 2007 Feb;18(2):426-40. Epub 2006 Nov 15.

3.

The unfolded protein response transducer Ire1p contains a nuclear localization sequence recognized by multiple beta importins.

Goffin L, Vodala S, Fraser C, Ryan J, Timms M, Meusburger S, Catimel B, Nice EC, Silver PA, Xiao CY, Jans DA, Gething MJ.

Mol Biol Cell. 2006 Dec;17(12):5309-23. Epub 2006 Oct 11.

4.

Association of stress proteins with autoantigens: a possible mechanism for triggering autoimmunity?

Purcell AW, Todd A, Kinoshita G, Lynch TA, Keech CL, Gething MJ, Gordon TP.

Clin Exp Immunol. 2003 May;132(2):193-200.

5.

The yeast inositol polyphosphate 5-phosphatase Inp54p localizes to the endoplasmic reticulum via a C-terminal hydrophobic anchoring tail: regulation of secretion from the endoplasmic reticulum.

Wiradjaja F, Ooms LM, Whisstock JC, McColl B, Helfenbaum L, Sambrook JF, Gething MJ, Mitchell CA.

J Biol Chem. 2001 Mar 9;276(10):7643-53. Epub 2000 Dec 14.

6.
7.

Presenilin mutants subvert chaperone function.

Gething MJ.

Nat Cell Biol. 2000 Feb;2(2):E21-3.

PMID:
10655596
8.

Role and regulation of the ER chaperone BiP.

Gething MJ.

Semin Cell Dev Biol. 1999 Oct;10(5):465-72. Review.

PMID:
10597629
9.

BiP-binding sequences in HIV gp160. Implications for the binding specificity of bip.

Knarr G, Modrow S, Todd A, Gething MJ, Buchner J.

J Biol Chem. 1999 Oct 15;274(42):29850-7.

11.

Substrate binding induces depolymerization of the C-terminal peptide binding domain of murine GRP78/BiP.

Chevalier M, King L, Wang C, Gething MJ, Elguindi E, Blond SY.

J Biol Chem. 1998 Oct 9;273(41):26827-35.

12.

HSP70 binding sites in the tumor suppressor protein p53.

Fourie AM, Hupp TR, Lane DP, Sang BC, Barbosa MS, Sambrook JF, Gething MJ.

J Biol Chem. 1997 Aug 1;272(31):19471-9.

13.

Protein folding. The difference with prokaryotes.

Gething MJ.

Nature. 1997 Jul 24;388(6640):329, 331. No abstract available.

PMID:
9237748
14.

Molecular chaperones: clasping the prize.

Gething MJ.

Curr Biol. 1996 Dec 1;6(12):1573-6. Review.

15.

Normal protein folding machinery.

Hartman D, Gething MJ.

EXS. 1996;77:3-24. Review.

PMID:
8856966
16.

BiP binding sequences in antibodies.

Knarr G, Gething MJ, Modrow S, Buchner J.

J Biol Chem. 1995 Nov 17;270(46):27589-94.

17.

Tissue-type plasminogen activator-induced invasion and metastasis of murine melanomas.

Alizadeh H, Ma D, Berman M, Bellingham D, Comerford SA, Gething MJ, Sambrook JF, Niederkorn JY.

Curr Eye Res. 1995 Jun;14(6):449-58.

PMID:
7671626
18.

Binding sites for Hsp70 molecular chaperones in natural proteins.

Gething MJ, Blond-Elguindi S, Buchner J, Fourie A, Knarr G, Modrow S, Nanu L, Segal M, Sambrook J.

Cold Spring Harb Symp Quant Biol. 1995;60:417-28. No abstract available.

PMID:
8824415
19.

Common and divergent peptide binding specificities of hsp70 molecular chaperones.

Fourie AM, Sambrook JF, Gething MJ.

J Biol Chem. 1994 Dec 2;269(48):30470-8.

20.

The pro region of human intestinal lactase-phlorizin hydrolase.

Naim HY, Jacob R, Naim H, Sambrook JF, Gething MJ.

J Biol Chem. 1994 Oct 28;269(43):26933-43. Erratum in: J Biol Chem 1994 Jan 13;270(2):986.

21.

The cellular response to unfolded proteins: intercompartmental signaling.

McMillan DR, Gething MJ, Sambrook J.

Curr Opin Biotechnol. 1994 Oct;5(5):540-5. Review.

PMID:
7765470
22.

Expression of lactase-phlorizin hydrolase in sheep is regulated at the RNA level.

Lacey SW, Naim HY, Magness RR, Gething MJ, Sambrook JF.

Biochem J. 1994 Sep 15;302 ( Pt 3):929-35.

23.

Interleukin-1 promotes hyperglycemia and insulitis in mice normally resistant to streptozotocin-induced diabetes.

Zunino SJ, Simons LF, Sambrook JF, Gething MJ.

Am J Pathol. 1994 Sep;145(3):661-70.

25.

Characterization of intraocular tumors arising in transgenic mice.

Anand R, Ma D, Alizadeh H, Comerford SA, Sambrook JF, Gething MJ, McLean IW, Niederkorn JY.

Invest Ophthalmol Vis Sci. 1994 Aug;35(9):3533-9.

PMID:
8056529
26.

Rejection of intraocular tumors from transgenic mice by tumor-infiltrating lymphocytes.

Ma D, Alizadeh H, Comerford SA, Gething MJ, Sambrook JF, Anand R, Niederkorn JY.

Curr Eye Res. 1994 May;13(5):361-9.

PMID:
7914482
27.

Capacity of simian virus 40 T antigen to induce self-tolerance but not immunological privilege in the anterior chamber of the eye.

Ma D, Comerford S, Bellingham D, Sambrook J, Gething MJ, Alizadeh H, Anand R, Mellon J, Niederkorn JY.

Transplantation. 1994 Mar 15;57(5):718-25.

PMID:
8140635
28.

Inhibitor-resistant tissue-type plasminogen activator: an improved thrombolytic agent in vitro.

Shohet RV, Spitzer S, Madison EL, Bassel-Duby R, Gething MJ, Sambrook JF.

Thromb Haemost. 1994 Jan;71(1):124-8.

PMID:
8165630
29.

Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP.

Blond-Elguindi S, Cwirla SE, Dower WJ, Lipshutz RJ, Sprang SR, Sambrook JF, Gething MJ.

Cell. 1993 Nov 19;75(4):717-28.

PMID:
7902213
30.

Converting tissue plasminogen activator to a zymogen: a regulatory triad of Asp-His-Ser.

Madison EL, Kobe A, Gething MJ, Sambrook JF, Goldsmith EJ.

Science. 1993 Oct 15;262(5132):419-21.

PMID:
8211162
31.
32.
33.

Proline isomerases function during heat shock.

Sykes K, Gething MJ, Sambrook J.

Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5853-7.

34.

Presentation of newly synthesized glycoproteins to CD4+ T lymphocytes. An analysis using influenza hemagglutinin transport mutants.

Kittlesen DJ, Brown LR, Braciale VL, Sambrook JP, Gething MJ, Braciale TJ.

J Exp Med. 1993 Apr 1;177(4):1021-30.

35.
36.

Glycosylation requirements for intracellular transport and function of the hemagglutinin of influenza virus.

Gallagher PJ, Henneberry JM, Sambrook JF, Gething MJ.

J Virol. 1992 Dec;66(12):7136-45.

37.

Cell-free synthesis of enzymically active tissue-type plasminogen activator. Protein folding determines the extent of N-linked glycosylation.

Bulleid NJ, Bassel-Duby RS, Freedman RB, Sambrook JF, Gething MJ.

Biochem J. 1992 Aug 15;286 ( Pt 1):275-80.

39.

A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins.

Mori K, Sant A, Kohno K, Normington K, Gething MJ, Sambrook JF.

EMBO J. 1992 Jul;11(7):2583-93.

40.

Disulfide bond formation during the folding of influenza virus hemagglutinin.

Segal MS, Bye JM, Sambrook JF, Gething MJ.

J Cell Biol. 1992 Jul;118(2):227-44.

41.

Tyrosine 67 in the epidermal growth factor-like domain of tissue-type plasminogen activator is important for clearance by a specific hepatic receptor.

Bassel-Duby R, Jiang NY, Bittick T, Madison E, McGookey D, Orth K, Shohet R, Sambrook J, Gething MJ.

J Biol Chem. 1992 May 15;267(14):9668-77.

42.

Protein folding in the cell.

Gething MJ, Sambrook J.

Nature. 1992 Jan 2;355(6355):33-45. Review.

PMID:
1731198
43.

Molecular chaperones: individualists or groupies?

Gething MJ.

Curr Opin Cell Biol. 1991 Aug;3(4):610-4. Review. No abstract available.

PMID:
1685325
45.

Restoration of serine protease-inhibitor interaction by protein engineering.

Madison EL, Goldsmith EJ, Gething MJ, Sambrook JF, Gerard RD.

J Biol Chem. 1990 Dec 15;265(35):21423-6.

46.

Complementing mutant alleles define three loci involved in mannosylation of Man5-GlcNAc2-P-P-dolichol in Chinese hamster ovary cells.

Beck PJ, Gething MJ, Sambrook J, Lehrman MA.

Somat Cell Mol Genet. 1990 Nov;16(6):539-48.

PMID:
2267628
47.
48.

The functional efficiency of a mammalian signal peptide is directly related to its hydrophobicity.

Bird P, Gething MJ, Sambrook J.

J Biol Chem. 1990 May 25;265(15):8420-5.

49.

The expression of influenza virus hemagglutinin in the pancreatic beta cells of transgenic mice results in autoimmune diabetes.

Roman LM, Simons LF, Hammer RE, Sambrook JF, Gething MJ.

Cell. 1990 May 4;61(3):383-96.

PMID:
2185889
50.

Amino acid residues that affect interaction of tissue-type plasminogen activator with plasminogen activator inhibitor 1.

Madison EL, Goldsmith EJ, Gerard RD, Gething MJ, Sambrook JF, Bassel-Duby RS.

Proc Natl Acad Sci U S A. 1990 May;87(9):3530-3.

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