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Items: 31

1.

Flavopiridol Inhibits TGF-β-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2.

Rostam MA, Shajimoon A, Kamato D, Mitra P, Piva TJ, Getachew R, Cao Y, Zheng W, Osman N, Little PJ.

J Pharmacol Exp Ther. 2018 Apr;365(1):156-164. doi: 10.1124/jpet.117.244483. Epub 2018 Feb 9.

PMID:
29438988
2.

Quantitative assessment of hand motor function in cervical spinal disorder patients using target tracking tests.

Lee SI, Huang A, Mortazavi B, Li C, Hoffman HA, Garst J, Lu DS, Getachew R, Espinal M, Razaghy M, Ghalehsari N, Paak BH, Ghavam AA, Afridi M, Ostowari A, Ghasemzadeh H, Lu DC, Sarrafzadeh M.

J Rehabil Res Dev. 2016;53(6):1007-1022. doi: 10.1682/JRRD.2014.12.0319.

3.

Multiple Growth Factors, But Not VEGF, Stimulate Glycosaminoglycan Hyperelongation in Retinal Choroidal Endothelial Cells.

Al Gwairi O, Osman N, Getachew R, Zheng W, Liang XL, Kamato D, Thach L, Little PJ.

Int J Biol Sci. 2016 Jul 18;12(9):1041-51. doi: 10.7150/ijbs.16134. eCollection 2016.

4.

An Investigation of Sodium Fusidate and Recombinant Cytochrome P450 Enzymes Inhibition In-Vitro.

Mishriky J, Balassone J, Bashour Z, Kaur S, Raman V, Getachew R, Osman N, Guidone D, Chan V, Little PJ.

Drug Metab Lett. 2016;10(3):180-186.

PMID:
27280598
5.

Evaluation of anti-malarial drugs' use in Fitche Hospital, North Shoa, Oromia Region, Ethiopia.

Getachew R, Amelo W, Bobasa EM.

J Pharm Bioallied Sci. 2016 Jan-Mar;8(1):39-42. doi: 10.4103/0975-7406.164294.

6.

Evaluation of the potential synergism of imatinib-related poly kinase inhibitors using growth factor stimulated proteoglycan synthesis as a model response.

Bernard R, Getachew R, Kamato D, Thach L, Osman N, Chan V, Zheng W, Little PJ.

J Pharm Pharmacol. 2016 Mar;68(3):368-78. doi: 10.1111/jphp.12530. Epub 2016 Feb 17.

PMID:
26888375
7.

Protease activated receptor-1 mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes.

Kamato D, Thach L, Getachew R, Burch M, Hollenberg MD, Zheng W, Little PJ, Osman N.

Cell Signal. 2016 Jan;28(1):110-9. doi: 10.1016/j.cellsig.2015.11.003. Epub 2015 Nov 5.

PMID:
26548632
8.

Transforming growth factor β-mediated site-specific Smad linker region phosphorylation in vascular endothelial cells.

Kamato D, Rostam MA, Piva TJ, Babaahmadi Rezaei H, Getachew R, Thach L, Bernard R, Zheng W, Little PJ, Osman N.

J Pharm Pharmacol. 2014 Dec;66(12):1722-33. doi: 10.1111/jphp.12298. Epub 2014 Oct 14.

PMID:
25316549
9.

Utilization of a novel digital measurement tool for quantitative assessment of upper extremity motor dexterity: a controlled pilot study.

Getachew R, Lee SI, Kimball JA, Yew AY, Lu DS, Li CH, Garst JH, Ghalehsari N, Paak BH, Razaghy M, Espinal M, Ostowari A, Ghavamrezaii AA, Pourtaheri S, Wu I, Sarrafzadeh M, Lu DC.

J Neuroeng Rehabil. 2014 Aug 13;11:121. doi: 10.1186/1743-0003-11-121.

10.

Atherogenic, fibrotic and glucose utilising actions of glucokinase activators on vascular endothelium and smooth muscle.

Al-aryahi S, Kamato D, Getachew R, Zheng W, Potocnik SJ, Cohen N, Guidone D, Osman N, Little PJ.

Cardiovasc Diabetol. 2014 Apr 15;13:80. doi: 10.1186/1475-2840-13-80.

11.

Platelet-derived growth factor-stimulated versican synthesis but not glycosaminoglycan elongation in vascular smooth muscle is mediated via Akt phosphorylation.

Osman N, Getachew R, Thach L, Wang H, Su X, Zheng W, Little PJ.

Cell Signal. 2014 May;26(5):912-6. doi: 10.1016/j.cellsig.2014.01.019. Epub 2014 Jan 23.

PMID:
24462709
12.

Minimally invasive tubular surgery for transforaminal lumbar interbody fusion.

Kimball J, Yew A, Getachew R, Lu DC.

Neurosurg Focus. 2013 Jul;35(2 Suppl):Video 19. doi: 10.3171/2013.V2.FOCUS13227.

PMID:
23829849
13.

Suramin inhibits PDGF-stimulated receptor phosphorylation, proteoglycan synthesis and glycosaminoglycan hyperelongation in human vascular smooth muscle cells.

Little PJ, Rostam MA, Piva TJ, Getachew R, Kamato D, Guidone D, Ballinger ML, Zheng W, Osman N.

J Pharm Pharmacol. 2013 Jul;65(7):1055-63. doi: 10.1111/jphp.12064. Epub 2013 Apr 24.

PMID:
23738733
14.

(S)-[6]-Gingerol inhibits TGF-β-stimulated biglycan synthesis but not glycosaminoglycan hyperelongation in human vascular smooth muscle cells.

Kamato D, Babaahmadi Rezaei H, Getachew R, Thach L, Guidone D, Osman N, Roufogalis B, Duke CC, Tran VH, Zheng W, Little PJ.

J Pharm Pharmacol. 2013 Jul;65(7):1026-36. doi: 10.1111/jphp.12060. Epub 2013 Mar 27.

PMID:
23738730
15.

Siah2-deficient mice show impaired skin wound repair.

Musyoka JN, Liu MC, Pouniotis DS, Wong CS, Bowtell DD, Little PJ, Getachew R, Möller A, Darby IA.

Wound Repair Regen. 2013 May-Jun;21(3):437-47. doi: 10.1111/wrr.12045. Epub 2013 Apr 29.

PMID:
23627548
16.

Thrombin-mediated proteoglycan synthesis utilizes both protein-tyrosine kinase and serine/threonine kinase receptor transactivation in vascular smooth muscle cells.

Burch ML, Getachew R, Osman N, Febbraio MA, Little PJ.

J Biol Chem. 2013 Mar 8;288(10):7410-9. doi: 10.1074/jbc.M112.400259. Epub 2013 Jan 18.

17.

Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

Luo J, Elwood F, Britschgi M, Villeda S, Zhang H, Ding Z, Zhu L, Alabsi H, Getachew R, Narasimhan R, Wabl R, Fainberg N, James ML, Wong G, Relton J, Gambhir SS, Pollard JW, Wyss-Coray T.

J Exp Med. 2013 Jan 14;210(1):157-72. doi: 10.1084/jem.20120412. Epub 2013 Jan 7.

18.

Smad2-dependent glycosaminoglycan elongation in aortic valve interstitial cells enhances binding of LDL to proteoglycans.

Osman N, Grande-Allen KJ, Ballinger ML, Getachew R, Marasco S, O'Brien KD, Little PJ.

Cardiovasc Pathol. 2013 Mar-Apr;22(2):146-55. doi: 10.1016/j.carpath.2012.07.002. Epub 2012 Sep 21.

19.

Genistein inhibits PDGF-stimulated proteoglycan synthesis in vascular smooth muscle without blocking PDGFβ receptor phosphorylation.

Little PJ, Getachew R, Rezaei HB, Sanchez-Guerrero E, Khachigian LM, Wang H, Liao S, Zheng W, Ballinger ML, Osman N.

Arch Biochem Biophys. 2012 Sep 1;525(1):25-31. doi: 10.1016/j.abb.2012.05.025. Epub 2012 Jun 7.

PMID:
22683649
20.

G protein coupled receptor transactivation: extending the paradigm to include serine/threonine kinase receptors.

Burch ML, Osman N, Getachew R, Al-Aryahi S, Poronnik P, Zheng W, Hill MA, Little PJ.

Int J Biochem Cell Biol. 2012 May;44(5):722-7. doi: 10.1016/j.biocel.2012.01.018. Epub 2012 Feb 2. Review.

PMID:
22326998
21.

TGF-β stimulates biglycan core protein synthesis but not glycosaminoglycan chain elongation via Akt phosphorylation in vascular smooth muscle.

Osman N, Getachew R, Burch M, Lancaster G, Wang R, Wang H, Zheng W, Little PJ.

Growth Factors. 2011 Oct;29(5):203-10. doi: 10.3109/08977194.2011.615747.

PMID:
21913799
22.

Endothelin-1 stimulation of proteoglycan synthesis in vascular smooth muscle is mediated by endothelin receptor transactivation of the transforming growth factor-[beta] type I receptor.

Little PJ, Burch ML, Getachew R, Al-aryahi S, Osman N.

J Cardiovasc Pharmacol. 2010 Oct;56(4):360-8. doi: 10.1097/FJC.0b013e3181ee6811.

PMID:
20625315
23.

PDGF beta-receptor kinase activity and ERK1/2 mediate glycosaminoglycan elongation on biglycan and increases binding to LDL.

Getachew R, Ballinger ML, Burch ML, Reid JJ, Khachigian LM, Wight TN, Little PJ, Osman N.

Endocrinology. 2010 Sep;151(9):4356-67. doi: 10.1210/en.2010-0027. Epub 2010 Jul 7.

PMID:
20610572
24.

Thrombin stimulation of proteoglycan synthesis in vascular smooth muscle is mediated by protease-activated receptor-1 transactivation of the transforming growth factor beta type I receptor.

Burch ML, Ballinger ML, Yang SN, Getachew R, Itman C, Loveland K, Osman N, Little PJ.

J Biol Chem. 2010 Aug 27;285(35):26798-805. doi: 10.1074/jbc.M109.092767. Epub 2010 Jun 22.

25.

TGF-beta stimulates biglycan synthesis via p38 and ERK phosphorylation of the linker region of Smad2.

Burch ML, Yang SN, Ballinger ML, Getachew R, Osman N, Little PJ.

Cell Mol Life Sci. 2010 Jun;67(12):2077-90. doi: 10.1007/s00018-010-0315-9. Epub 2010 Mar 7.

PMID:
20213272
26.

Characterisation of Ki11502 as a potent inhibitor of PDGF beta receptor-mediated proteoglycan synthesis in vascular smooth muscle cells.

Getachew R, Ballinger ML, Burch ML, Little PJ, Osman N.

Eur J Pharmacol. 2010 Jan 25;626(2-3):186-92. doi: 10.1016/j.ejphar.2009.09.066. Epub 2009 Oct 8.

PMID:
19818754
27.

Growth factor-mediated hyper-elongation of glycosaminoglycan chains on biglycan requires transcription and translation.

Yang SN, Burch ML, Getachew R, Ballinger ML, Osman N, Little PJ.

Arch Physiol Biochem. 2009 Jul;115(3):147-54. doi: 10.1080/13813450903110754.

PMID:
19580379
28.

p38 MAP kinase mediated proteoglycan synthesis as a target for the prevention of atherosclerosis.

Osman N, Ballinger ML, Dadlani HM, Getachew R, Burch ML, Little PJ.

Cardiovasc Hematol Disord Drug Targets. 2008 Dec;8(4):287-92. Review.

PMID:
19075640
29.

Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation.

Kwon HS, Brent MM, Getachew R, Jayakumar P, Chen LF, Schnolzer M, McBurney MW, Marmorstein R, Greene WC, Ott M.

Cell Host Microbe. 2008 Mar 13;3(3):158-67. doi: 10.1016/j.chom.2008.02.002.

30.

Smad and p38 MAP kinase-mediated signaling of proteoglycan synthesis in vascular smooth muscle.

Dadlani H, Ballinger ML, Osman N, Getachew R, Little PJ.

J Biol Chem. 2008 Mar 21;283(12):7844-52. doi: 10.1074/jbc.M703125200. Epub 2008 Jan 25.

31.

Severe calcinosis cutis in an infant.

Puvabanditsin S, Garrow E, Titapiwatanakun R, Getachew R, Patel JB.

Pediatr Radiol. 2005 May;35(5):539-42. Epub 2004 Nov 23.

PMID:
15565339

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