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Items: 1 to 50 of 73

1.

Paradoxical effects of platelet-derived growth factor-A overexpression in malignant mesothelioma. Antiproliferative effects in vitro and tumorigenic stimulation in vivo.

Metheny-Barlow LJ, Flynn B, van Gijssel HE, Marrogi A, Gerwin BI.

Am J Respir Cell Mol Biol. 2001 Jun;24(6):694-702.

PMID:
11415934
2.
3.
4.

ErbB-2 kinase is required for constitutive stat 3 activation in malignant human lung epithelial cells.

Fernandes A, Hamburger AW, Gerwin BI.

Int J Cancer. 1999 Nov 12;83(4):564-70.

5.

Production of epidermal growth factor related ligands in tumorigenic and benign human lung epithelial cells.

Fernandes AM, Hamburger AW, Gerwin BI.

Cancer Lett. 1999 Jul 19;142(1):55-63.

PMID:
10424781
6.

Asbestos induction of extended lifespan in normal human mesothelial cells: interindividual susceptibility and SV40 T antigen.

Xu L, Flynn BJ, Ungar S, Pass HI, Linnainmaa K, Mattson K, Gerwin BI.

Carcinogenesis. 1999 May;20(5):773-83.

PMID:
10334193
7.

Resistance of pleural mesothelioma cell lines to apoptosis: relation to expression of Bcl-2 and Bax.

Narasimhan SR, Yang L, Gerwin BI, Broaddus VC.

Am J Physiol. 1998 Jul;275(1):L165-71. doi: 10.1152/ajplung.1998.275.1.L165.

PMID:
9688948
8.
9.

Oncogenes and tumor-suppressor genes in mesothelioma--a synopsis.

Lechner JF, Tesfaigzi J, Gerwin BI.

Environ Health Perspect. 1997 Sep;105 Suppl 5:1061-7. Review.

10.

TGF-beta1 resistance is not associated with alterations in TGF-beta type II receptors in immortalized human lung epithelial cells.

Hamburger AW, Smith T, Elliget K, Hagiwara K, Gerwin BI.

Cancer Lett. 1997 Feb 26;113(1-2):65-70.

PMID:
9065803
11.

High levels of MDM2 are not correlated with the presence of wild-type p53 in human malignant mesothelioma cell lines.

Ungar S, Van de Meeren A, Tammilehto L, Linnainmaa K, Mattson K, Gerwin BI.

Br J Cancer. 1996 Nov;74(10):1534-40.

12.

Cytokine signaling in mesothelial cells: receptor expression closes the autocrine loop.

Gerwin BI.

Am J Respir Cell Mol Biol. 1996 Jun;14(6):505-7. Review. No abstract available.

PMID:
8652178
13.

SV40-induced immortalization and ras-transformation of human bronchial epithelial cells.

Reddel RR, De Silva R, Duncan EL, Rogan EM, Whitaker NJ, Zahra DG, Ke Y, McMenamin MG, Gerwin BI, Harris CC.

Int J Cancer. 1995 Apr 10;61(2):199-205.

PMID:
7705948
14.

Asbestos and the mesothelial cell: a molecular trail to mitogenic stimuli and suppressor gene suspects.

Gerwin BI.

Am J Respir Cell Mol Biol. 1994 Nov;11(5):507-8. Review. No abstract available.

PMID:
7946379
15.
16.

Induction of anchorage independent growth and serum resistance in immortalized human bronchial epithelial cells by alteration of the cytoskeleton.

De Silva R, Englezou A, Schevzov G, Gerwin BI, Harris CC, Gunning P, Reddel RR.

Cell Mol Biol Res. 1994;40(4):323-35.

PMID:
7866433
17.

Biological consequences of overexpression of a transfected c-erbB-2 gene in immortalized human bronchial epithelial cells.

Noguchi M, Murakami M, Bennett W, Lupu R, Hui F Jr, Harris CC, Gerwin BI.

Cancer Res. 1993 May 1;53(9):2035-43.

18.

Development of tumorigenicity in simian virus 40-immortalized human bronchial epithelial cell lines.

Reddel RR, Salghetti SE, Willey JC, Ohnuki Y, Ke Y, Gerwin BI, Lechner JF, Harris CC.

Cancer Res. 1993 Mar 1;53(5):985-91.

19.

Tumorigenic conversion of human mesothelial cells as a consequence of platelet-derived growth factor-A chain overexpression.

Van der Meeren A, Seddon MB, Betsholtz CA, Lechner JF, Gerwin BI.

Am J Respir Cell Mol Biol. 1993 Feb;8(2):214-21.

PMID:
8427711
20.

Human mesothelioma cells and asbestos-exposed mesothelial cells are selectively resistant to amosite toxicity: a possible mechanism for tumor promotion by asbestos.

Gabrielson EW, Van der Meeren A, Reddel RR, Reddel H, Gerwin BI, Harris CC.

Carcinogenesis. 1992 Aug;13(8):1359-63.

PMID:
1323425
21.

p53 and Kirsten-ras mutations in human mesothelioma cell lines.

Metcalf RA, Welsh JA, Bennett WP, Seddon MB, Lehman TA, Pelin K, Linnainmaa K, Tammilehto L, Mattson K, Gerwin BI, et al.

Cancer Res. 1992 May 1;52(9):2610-5.

22.

Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor beta 1.

Gerwin BI, Spillare E, Forrester K, Lehman TA, Kispert J, Welsh JA, Pfeifer AM, Lechner JF, Baker SJ, Vogelstein B, et al.

Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2759-63.

23.

Overexpression of the p185erB-2 tyrosine kinase growth factor receptor: control or chaos.

Gerwin BI.

Am J Respir Cell Mol Biol. 1992 Apr;6(4):357-8. Review. No abstract available.

PMID:
1347998
24.

A human bronchial epithelial cell strain with unusual in vitro growth potential which undergoes neoplastic transformation after SV40 T antigen gene transfection.

Reddel RR, Hsu IC, Mass MJ, Hukku B, Gerwin BI, Salghetti SE, Somers AN, Galati AJ, Gunning WT 3rd, Harris CC, et al.

Int J Cancer. 1991 Jul 9;48(5):764-73.

PMID:
1712759
25.

Oncogenes and tumor-suppressor genes.

Lehman TA, Reddel R, Peiifer AM, Spillare E, Kaighn ME, Weston A, Gerwin BI, Harris CC.

Environ Health Perspect. 1991 Jun;93:133-44. Review.

26.

TGF-beta 1 modulation of urokinase and PAI-1 expression in human bronchial epithelial cells.

Gerwin BI, Keski-Oja J, Seddon M, Lechner JF, Harris CC.

Am J Physiol. 1990 Oct;259(4 Pt 1):L262-9.

PMID:
2221087
27.
28.

Asbestos-related malignant mesothelioma: growth, cytology, tumorigenicity and consistent chromosome findings in cell lines from five patients.

Pelin-Enlund K, Husgafvel-Pursiainen K, Tammilehto L, Klockars M, Jantunen K, Gerwin BI, Harris CC, Tuomi T, Vanhala E, Mattson K, et al.

Carcinogenesis. 1990 Apr;11(4):673-81.

PMID:
2323006
29.

Expression of chromosomal proteins HMG-14 and HMG-17 in transformed human cells.

Crippa MP, Pash JM, Gerwin BI, Smithgall TE, Glazer RI, Bustin M.

Cancer Res. 1990 Apr 1;50(7):2022-6.

30.

Tumorigenicity of human mesothelial cell line transfected with EJ-ras oncogene.

Reddel RR, Malan-Shibley L, Gerwin BI, Metcalf RA, Harris CC.

J Natl Cancer Inst. 1989 Jun 21;81(12):945-8.

PMID:
2733039
31.

Establishment of a human in vitro mesothelial cell model system for investigating mechanisms of asbestos-induced mesothelioma.

Ke Y, Reddel RR, Gerwin BI, Reddel HK, Somers AN, McMenamin MG, LaVeck MA, Stahel RA, Lechner JF, Harris CC.

Am J Pathol. 1989 May;134(5):979-91.

32.

Differential responses to growth factors by normal human mesothelial cultures from individual donors.

Lechner JF, LaVeck MA, Gerwin BI, Matis EA.

J Cell Physiol. 1989 May;139(2):295-300.

PMID:
2497107
33.

Effects of palytoxin or ouabain on growth and squamous differentiation of human bronchial epithelial cells in vitro.

Bonnard C, Lechner JF, Gerwin BI, Fujiki H, Harris CC.

Carcinogenesis. 1988 Dec;9(12):2245-9.

PMID:
2903801
34.

Dissimilar peptide growth factors can induce normal human mesothelial cell multiplication.

Laveck MA, Somers AN, Moore LL, Gerwin BI, Lechner JF.

In Vitro Cell Dev Biol. 1988 Nov;24(11):1077-84.

PMID:
2461356
35.
36.

Stimulation of DNA synthesis in cultured primary human mesothelial cells by specific growth factors.

Gabrielson EW, Gerwin BI, Harris CC, Roberts AB, Sporn MB, Lechner JF.

FASEB J. 1988 Aug;2(11):2717-21.

PMID:
3260881
37.

Human bronchial epithelial cells with integrated SV40 virus T antigen genes retain the ability to undergo squamous differentiation.

Ke Y, Reddel RR, Gerwin BI, Miyashita M, McMenamin M, Lechner JF, Harris CC.

Differentiation. 1988 Jun;38(1):60-6.

PMID:
2846394
38.
39.

Comparison of production of transforming growth factor-beta and platelet-derived growth factor by normal human mesothelial cells and mesothelioma cell lines.

Gerwin BI, Lechner JF, Reddel RR, Roberts AB, Robbins KC, Gabrielson EW, Harris CC.

Cancer Res. 1987 Dec 1;47(23):6180-4.

40.

Functional analysis of reverse transcription by a frameshift pol mutant of murine leukemia virus.

Messer LI, Currey KM, O'Neill BJ, Maizel JV Jr, Levin JG, Gerwin BI.

Virology. 1985 Oct 15;146(1):146-52.

PMID:
2412343
41.
42.

Sites of single-strand breaks in DNA treated with a diol-epoxide of benz[a]anthracene.

Cooper CS, Gerwin BI, Scheiner LA.

Carcinogenesis. 1983 Dec;4(12):1645-9.

PMID:
6317219
43.

Molecular properties of a gag- pol- env+ murine leukemia virus from cultured AKR lymphoma cells.

Rein A, Lowy DR, Gerwin BI, Ruscetti SK, Bassin RH.

J Virol. 1982 Feb;41(2):626-34.

44.

Macromolecular requirements for abrogation of Fv-1 restriction by murine leukemia viruses.

Bassin RH, Gerwin BI, Levin JG, Duran-Troise G, Benjers BM, Rein A.

J Virol. 1980 Aug;35(2):287-97.

45.

Isolation of a replication-defective murine leukaemia virus from cultured AKR leukaemia cells.

Rein A, Athan E, Benjers BM, Bassin RH, Gerwin BI, Slocum DR.

Nature. 1979 Dec 13;282(5740):753-4.

PMID:
229420
46.

Mechanism of restriction of murine leukemia viruses varies between different strains of Fv-1n mice.

Benjers BM, Bassin RH, Rein A, Gerwin BI, Duran-Troise G.

Int J Cancer. 1979 Nov 15;24(5):600-7. No abstract available.

PMID:
231017
47.

Mutant of B-tropic murine leukemia virus synthesizing an altered polymerase molecule.

Gerwin BI, Rein A, Levin JG, Bassin RH, Benjers BM, Kashmiri SV, Hopkins D, O'Neill BJ.

J Virol. 1979 Sep;31(3):741-51.

48.

Rescue and transmission of a replication-defective variant of moloney murine leukemia virus.

Rein A, Benjers BM, Gerwin BI, Bassin RH, Slocum DR.

J Virol. 1979 Feb;29(2):494-500.

49.
50.

A replication-defective variant of Moloney murine leukemia virus. I. Biological characterization.

Rein AL, Gerwin BI, Bassin RH, Schwarm L, Schidlovsky G.

J Virol. 1978 Jan;25(1):146-56.

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