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Items: 1 to 50 of 79

1.

The Relative Biological Effect of Spread-Out Bragg Peak Protons in Sensitive and Resistant Tumor Cells.

Lin YF, Chen BP, Li W, Perko Z, Wang Y, Testa M, Schneider R, Lu HM, Gerweck LE.

Int J Part Ther. 2018 Winter;4(3):33-39. doi: 10.14338/IJPT-17-00025.1. Epub 2018 Mar 21.

2.

Topogram-based tube current modulation of head computed tomography for optimizing image quality while protecting the eye lens with shielding.

Lin MF, Chen CY, Lee YH, Li CW, Gerweck LE, Wang H, Chan WP.

Acta Radiol. 2019 Jan;60(1):61-67. doi: 10.1177/0284185118770894. Epub 2018 Apr 17.

PMID:
29665705
3.

MicroRNA-378 enhances radiation response in ectopic and orthotopic implantation models of glioblastoma.

Li W, Liu Y, Yang W, Han X, Li S, Liu H, Gerweck LE, Fukumura D, Loeffler JS, Yang BB, Jain RK, Huang P.

J Neurooncol. 2018 Jan;136(1):63-71. doi: 10.1007/s11060-017-2646-y. Epub 2017 Oct 28.

4.

At the Crossroads of Cancer Stem Cells, Radiation Biology, and Radiation Oncology.

Gerweck LE, Wakimoto H.

Cancer Res. 2016 Mar 1;76(5):994-8. doi: 10.1158/0008-5472.CAN-15-2455. Epub 2016 Feb 15. Review.

5.

Regulation of DNA Damage Response by Estrogen Receptor β-Mediated Inhibition of Breast Cancer Associated Gene 2.

Lee YH, Sun Y, Gerweck LE, Glickman RD.

Biomedicines. 2015 Apr 21;3(2):182-200. doi: 10.3390/biomedicines3020182.

6.

Radiobiological intercomparison of the 160 MeV and 230 MeV proton therapy beams at the Harvard Cyclotron Laboratory and at Massachusetts General Hospital.

Wouters BG, Skarsgard LD, Gerweck LE, Carabe-Fernandez A, Wong M, Durand RE, Nielson D, Bussiere MR, Wagner M, Biggs P, Paganetti H, Suit HD.

Radiat Res. 2015 Feb;183(2):174-87. doi: 10.1667/RR13795.1. Epub 2015 Jan 14. Erratum in: Radiat Res. 2015 Apr;183(4):e51.

PMID:
25587741
7.

Determinates of tumor response to radiation: tumor cells, tumor stroma and permanent local control.

Li W, Huang P, Chen DJ, Gerweck LE.

Radiother Oncol. 2014 Oct;113(1):146-9. doi: 10.1016/j.radonc.2014.09.006. Epub 2014 Oct 2.

8.

Lifetime increased cancer risk in mice following exposure to clinical proton beam-generated neutrons.

Gerweck LE, Huang P, Lu HM, Paganetti H, Zhou Y.

Int J Radiat Oncol Biol Phys. 2014 May 1;89(1):161-6. doi: 10.1016/j.ijrobp.2014.01.057.

9.

Modification of cell lethality at elevated temperatures the pH effect 1977.

Gerweck LE.

Radiat Res. 2012 Aug;178(2):AV198-203. No abstract available.

PMID:
22870970
10.

Dose-rate effects in external beam radiotherapy redux.

Ling CC, Gerweck LE, Zaider M, Yorke E.

Radiother Oncol. 2010 Jun;95(3):261-8. doi: 10.1016/j.radonc.2010.03.014. Epub 2010 Apr 1. Review.

PMID:
20363041
11.

Perivascular nitric oxide gradients normalize tumor vasculature.

Kashiwagi S, Tsukada K, Xu L, Miyazaki J, Kozin SV, Tyrrell JA, Sessa WC, Gerweck LE, Jain RK, Fukumura D.

Nat Med. 2008 Mar;14(3):255-7. doi: 10.1038/nm1730. Epub 2008 Feb 17.

PMID:
18278052
12.

Influence of tumor cell and stroma sensitivity on tumor response to radiation.

Ogawa K, Boucher Y, Kashiwagi S, Fukumura D, Chen D, Gerweck LE.

Cancer Res. 2007 May 1;67(9):4016-21.

13.

Tumor cell radiosensitivity is a major determinant of tumor response to radiation.

Gerweck LE, Vijayappa S, Kurimasa A, Ogawa K, Chen DJ.

Cancer Res. 2006 Sep 1;66(17):8352-5.

14.

Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics.

Gerweck LE, Vijayappa S, Kozin S.

Mol Cancer Ther. 2006 May;5(5):1275-9.

15.

Relative biological effectiveness (RBE) values for proton beam therapy.

Paganetti H, Niemierko A, Ancukiewicz M, Gerweck LE, Goitein M, Loeffler JS, Suit HD.

Int J Radiat Oncol Biol Phys. 2002 Jun 1;53(2):407-21.

PMID:
12023146
16.

The pH difference between tumor and normal tissue offers a tumor specific target for the treatment of cancer.

Gerweck LE.

Drug Resist Updat. 2000 Feb;3(1):49-50. No abstract available.

PMID:
11498365
17.
19.

Relative biological effectiveness of proton beams in clinical therapy.

Gerweck LE, Kozin SV.

Radiother Oncol. 1999 Feb;50(2):135-42. Review.

PMID:
10368035
20.
21.

Enhancement of fractionated-dose irradiation by retinoic acid plus interferon.

Gerweck LE, Zaidi ST, Delaney TF.

Int J Radiat Oncol Biol Phys. 1998 Oct 1;42(3):611-5.

PMID:
9806522
23.

Tumor pH: implications for treatment and novel drug design.

Gerweck LE.

Semin Radiat Oncol. 1998 Jul;8(3):176-82. Review.

PMID:
9634494
24.

Effect of basic fibroblast growth factor on angiogenesis and growth of isografted bone: quantitative in vitro-in vivo analysis in mice.

Leunig M, Yuan F, Gerweck LE, Jain RK.

Int J Microcirc Clin Exp. 1997 Jan-Feb;17(1):1-9.

PMID:
9176719
25.

The effect of androgen deprivation and radiation therapy on an androgen-sensitive murine tumor: an in vitro and in vivo study.

Zietman AL, Nakfoor BM, Prince EA, Gerweck LE.

Cancer J Sci Am. 1997 Jan-Feb;3(1):31-6.

PMID:
9072305
26.

Heating or freezing bone. Effects on angiogenesis induction and growth potential in mice.

Leunig M, Yuan F, Berk DA, Gerweck LE, Jain RK.

Acta Orthop Scand. 1996 Aug;67(4):383-8.

PMID:
8792744
27.
28.
29.

PO2 in irradiated versus nonirradiated tumors of mice breathing oxygen at normal and elevated pressure.

Gerweck LE, Hetzel FW.

Int J Radiat Oncol Biol Phys. 1995 Jun 15;32(3):695-701.

PMID:
7790256
30.

Quantitative analysis of angiogenesis and growth of bone: effect of indomethacin exposure in a combined in vitro-in vivo approach.

Leunig M, Yuan F, Gerweck LE, Berk DA, Jain RK.

Res Exp Med (Berl). 1995;195(5):275-88.

PMID:
8578003
31.

Energy status parameters, hypoxia fraction and radiocurability across tumor types.

Gerweck LE, Koutcher J, Zaidi ST.

Acta Oncol. 1995;34(3):335-8.

PMID:
7779419
32.

Angiogenesis and growth of isografted bone: quantitative in vivo assay in nude mice.

Leunig M, Yuan F, Berk DA, Gerweck LE, Jain RK.

Lab Invest. 1994 Aug;71(2):300-7.

PMID:
7521447
33.

Influence of experimental factors on intrinsic radiosensitivity assays at low doses of radiation: cell multiplicity.

Gerweck LE, Dullea R, Zaidi ST, Budach W, Hartford A.

Radiat Res. 1994 Jun;138(3):361-6.

PMID:
8184010
34.

Multivariate determinants of radiocurability. I: Prediction of single fraction tumor control doses.

Gerweck LE, Zaidi ST, Zietman A.

Int J Radiat Oncol Biol Phys. 1994 Apr 30;29(1):57-66.

PMID:
8175446
35.

Energy status and radiobiological hypoxia at specified oxygen concentrations.

Gerweck LE, Seneviratne T, Gerweck KK.

Radiat Res. 1993 Jul;135(1):69-74.

PMID:
8327663
36.

Energy status in the murine FSaII and MCaIV tumors under aerobic and hypoxic conditions: an in-vivo and in-vitro analysis.

Gerweck LE, Koutcher JA, Zaidi ST, Seneviratne T.

Int J Radiat Oncol Biol Phys. 1992;23(3):557-61.

PMID:
1612956
37.

Regulation of pH in murine tumor and muscle.

Gerweck LE, Rhee JG, Koutcher JA, Song CW, Urano M.

Radiat Res. 1991 May;126(2):206-9.

PMID:
2023990
38.

The simultaneous determination of intracellular pH and cell energy status.

Gerweck LE, Fellenz MP.

Radiat Res. 1991 Mar;125(3):257-61.

PMID:
2000448
39.

31P NMR spectra of extremity sarcomas: diversity of metabolic profiles and changes in response to chemotherapy.

Koutcher JA, Ballon D, Graham M, Healey JH, Casper ES, Heelan R, Gerweck LE.

Magn Reson Med. 1990 Oct;16(1):19-34.

PMID:
2175008
40.

Relationship of changes in pH and energy status to hypoxic cell fraction and hyperthermia sensitivity.

Koutcher JA, Barnett D, Kornblith AB, Cowburn D, Brady TJ, Gerweck LE.

Int J Radiat Oncol Biol Phys. 1990 Jun;18(6):1429-35.

PMID:
2370193
41.
42.

Relationship between energy status, hypoxic cell fraction, and hyperthermic sensitivity in a murine fibrosarcoma.

Gerweck LE, Urano M, Koutcher J, Fellenz MP, Kahn J.

Radiat Res. 1989 Mar;117(3):448-58.

PMID:
2928469
43.
44.

FSaII mouse tumor metabolic changes with different doses of glucose measured by 31P nuclear magnetic resonance.

Koutcher JA, Fellenz MP, Vaupel PW, Gerweck LE.

Cancer Res. 1988 Nov 1;48(21):5917-21.

45.

Biological and clinical aspects of hyperthermia in cancer therapy.

Oleson JR, Calderwood SK, Coughlin CT, Dewhirst MW, Gerweck LE, Gibbs FA Jr, Kapp DS.

Am J Clin Oncol. 1988 Jun;11(3):368-80. Review. No abstract available.

PMID:
3289367
46.

Lonidamine-induced, pH dependent inhibition of cellular oxygen utilization.

Stryker JA, Gerweck LE.

Radiat Res. 1988 Feb;113(2):356-61.

PMID:
3340739
47.

Variability in the kinetics of thermotolerance decay in three cell lines.

Gerweck LE, Majima H.

Radiat Res. 1987 Nov;112(2):365-73.

PMID:
3685262
48.

Cell proliferation, protein turnover, and the decay of thermotolerance in CHO cells.

Gerweck LE, Epstein LF.

Radiat Res. 1986 Jun;106(3):311-20.

PMID:
3714978
49.

Temperature-dependent influence of thiols upon glutathione levels in Chinese hamster ovary cells at cytotoxic concentrations.

Issels RD, Bourier S, Biaglow JE, Gerweck LE, Wilmanns W.

Cancer Res. 1985 Dec;45(12 Pt 1):6219-24.

50.

Hyperthermia in cancer therapy: the biological basis and unresolved questions.

Gerweck LE.

Cancer Res. 1985 Aug;45(8):3408-14. Review. No abstract available.

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